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Showing 841 to 852 of 852 entries
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Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons.

eLife

He XJ, Patel J, Weiss CE, Ma X, Bloodgood BL, Banghart MR.
PMID: 34787079
Elife. 2021 Nov 17;10. doi: 10.7554/eLife.69746.

Functional interactions between G protein-coupled receptors are poised to enhance neuronal sensitivity to neuromodulators and therapeutic drugs. Mu and delta opioid receptors (MORs and DORs) can interact when overexpressed in the same cells, but whether co-expression of endogenous MORs...

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He XJ, Patel J, Weiss CE, et al. Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons. Elife. 2021;10doi: 10.7554/eLife.69746.
He, X. J., Patel, J., Weiss, C. E., Ma, X., Bloodgood, B. L., & Banghart, M. R. (2021). Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons. eLife, 10. https://doi.org/10.7554/eLife.69746
He, Xinyi Jenny, et al. "Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons." eLife vol. 10 (2021). doi: https://doi.org/10.7554/eLife.69746
He XJ, Patel J, Weiss CE, Ma X, Bloodgood BL, Banghart MR. Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons. Elife. 2021 Nov 17;10. doi: 10.7554/eLife.69746. PMID: 34787079; PMCID: PMC8716102.
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Something's fishy: cardiovascular ATP-sensitive K.

The Journal of physiology

Jackson WF.
PMID: 34951483
J Physiol. 2022 Jan;600(2):169-170. doi: 10.1113/JP282628. Epub 2022 Jan 03.

No abstract available.

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Jackson WF. Something's fishy: cardiovascular ATP-sensitive K. J Physiol. 2022;600(2):169-170doi: 10.1113/JP282628.
Jackson, W. F. (2022). Something's fishy: cardiovascular ATP-sensitive K. The Journal of physiology, 600(2), 169-170. https://doi.org/10.1113/JP282628
Jackson, William F. "Something's fishy: cardiovascular ATP-sensitive K." The Journal of physiology vol. 600,2 (2022): 169-170. doi: https://doi.org/10.1113/JP282628
Jackson WF. Something's fishy: cardiovascular ATP-sensitive K. J Physiol. 2022 Jan;600(2):169-170. doi: 10.1113/JP282628. Epub 2022 Jan 03. PMID: 34951483.
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Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages.

Pharmacological reports : PR

Selezneva A, Yoshida M, Gibb A, Willis D.
PMID: 33713314
Pharmacol Rep. 2021 Jun;73(3):881-890. doi: 10.1007/s43440-021-00229-z. Epub 2021 Mar 13.

BACKGROUND: Macrophages are important cells of the innate immune system and contribute to a variety of physiological and pathophysiological responses. Monovalent and divalent ion channels have been studied in macrophage function, and while much research is still required, a...

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Selezneva A, Yoshida M, Gibb A, et al. Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages. Pharmacol Rep. 2021;73(3):881-890doi: 10.1007/s43440-021-00229-z.
Selezneva, A., Yoshida, M., Gibb, A., & Willis, D. (2021). Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages. Pharmacological reports : PR, 73(3), 881-890. https://doi.org/10.1007/s43440-021-00229-z
Selezneva, Anna, et al. "Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages." Pharmacological reports : PR vol. 73,3 (2021): 881-890. doi: https://doi.org/10.1007/s43440-021-00229-z
Selezneva A, Yoshida M, Gibb A, Willis D. Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages. Pharmacol Rep. 2021 Jun;73(3):881-890. doi: 10.1007/s43440-021-00229-z. Epub 2021 Mar 13. PMID: 33713314; PMCID: PMC8180476.
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Deletion of the Wilms' Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development.

Frontiers in cell and developmental biology

Díaz Del Moral S, Barrena S, Hernández-Torres F, Aránega A, Villaescusa JM, Gómez Doblas JJ, Franco D, Jiménez-Navarro M, Muñoz-Chápuli R, Carmona R.
PMID: 34368133
Front Cell Dev Biol. 2021 Jul 22;9:683861. doi: 10.3389/fcell.2021.683861. eCollection 2021.

Expression of Wilms' tumor suppressor transcription factor (WT1) in the embryonic epicardium is essential for cardiac development, but its myocardial expression is little known. We have found that WT1 is expressed at low levels in 20-25% of the embryonic...

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Díaz Del Moral S, Barrena S, Hernández-Torres F, et al. Deletion of the Wilms' Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development. Front Cell Dev Biol. 2021;9:683861doi: 10.3389/fcell.2021.683861.
Díaz Del Moral, S., Barrena, S., Hernández-Torres, F., Aránega, A., Villaescusa, J. M., Gómez Doblas, J. J., Franco, D., Jiménez-Navarro, M., Muñoz-Chápuli, R., & Carmona, R. (2021). Deletion of the Wilms' Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development. Frontiers in cell and developmental biology, 9683861. https://doi.org/10.3389/fcell.2021.683861
Díaz Del Moral, Sandra, et al. "Deletion of the Wilms' Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development." Frontiers in cell and developmental biology vol. 9 (2021): 683861. doi: https://doi.org/10.3389/fcell.2021.683861
Díaz Del Moral S, Barrena S, Hernández-Torres F, Aránega A, Villaescusa JM, Gómez Doblas JJ, Franco D, Jiménez-Navarro M, Muñoz-Chápuli R, Carmona R. Deletion of the Wilms' Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development. Front Cell Dev Biol. 2021 Jul 22;9:683861. doi: 10.3389/fcell.2021.683861. eCollection 2021. PMID: 34368133; PMCID: PMC8339973.
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Amiodarone-Induced Neutropenia: An Uncommon Side Effect of a Common Drug.

Cureus

Kohli A, Sharma AV.
PMID: 33194480
Cureus. 2020 Oct 12;12(10):e10913. doi: 10.7759/cureus.10913.

Amiodarone is widely used as an antiarrhythmic agent for the treatment of both supraventricular and ventricular arrhythmias in various inpatient as well as outpatient settings. Classified as a class III antiarrhythmic agent, it acts mainly by inhibition of potassium...

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Kohli A, Sharma AV. Amiodarone-Induced Neutropenia: An Uncommon Side Effect of a Common Drug. Cureus. 2020;12(10):e10913doi: 10.7759/cureus.10913.
Kohli, A., & Sharma, A. V. (2020). Amiodarone-Induced Neutropenia: An Uncommon Side Effect of a Common Drug. Cureus, 12(10), e10913. https://doi.org/10.7759/cureus.10913
Kohli, Akshay, and Sharma, Avinash V. "Amiodarone-Induced Neutropenia: An Uncommon Side Effect of a Common Drug." Cureus vol. 12,10 (2020): e10913. doi: https://doi.org/10.7759/cureus.10913
Kohli A, Sharma AV. Amiodarone-Induced Neutropenia: An Uncommon Side Effect of a Common Drug. Cureus. 2020 Oct 12;12(10):e10913. doi: 10.7759/cureus.10913. PMID: 33194480; PMCID: PMC7657372.
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Physiological role of K.

Peptides

Demirel S, Sahinturk S, Isbil N, Ozyener F.
PMID: 34748790
Peptides. 2021 Nov 05;147:170685. doi: 10.1016/j.peptides.2021.170685. Epub 2021 Nov 05.

Irisin, an exercise-induced myokine, has been shown to have a peripheral vasodilator effect. However, little is known about the mechanisms underlying its effects. In this study, it was aimed to investigate the vasoactive effects of irisin on rat thoracic...

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Demirel S, Sahinturk S, Isbil N, et al. Physiological role of K. Peptides. 2021;147:170685doi: 10.1016/j.peptides.2021.170685.
Demirel, S., Sahinturk, S., Isbil, N., & Ozyener, F. (2021). Physiological role of K. Peptides, 147170685. https://doi.org/10.1016/j.peptides.2021.170685
Demirel, Sadettin, et al. "Physiological role of K." Peptides vol. 147 (2021): 170685. doi: https://doi.org/10.1016/j.peptides.2021.170685
Demirel S, Sahinturk S, Isbil N, Ozyener F. Physiological role of K. Peptides. 2021 Nov 05;147:170685. doi: 10.1016/j.peptides.2021.170685. Epub 2021 Nov 05. PMID: 34748790.
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Antibodies Targeting K.

Bioelectricity

Hernandez-Resendiz I, Hartung F, Pardo LA.
PMID: 34471820
Bioelectricity. 2019 Sep 01;1(3):180-187. doi: 10.1089/bioe.2019.0022. Epub 2019 Sep 16.

Voltage-gated potassium channels are transmembrane proteins that allow flow of potassium across the membrane to regulate ion homeostasis, cell proliferation, migration, cell volume, and specific processes such as muscular contraction. Aberrant function or expression of potassium channels can underlie...

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Hernandez-Resendiz I, Hartung F, Pardo LA. Antibodies Targeting K. Bioelectricity. 2019;1(3):180-187doi: 10.1089/bioe.2019.0022.
Hernandez-Resendiz, I., Hartung, F., & Pardo, L. A. (2019). Antibodies Targeting K. Bioelectricity, 1(3), 180-187. https://doi.org/10.1089/bioe.2019.0022
Hernandez-Resendiz, Ileana, et al. "Antibodies Targeting K." Bioelectricity vol. 1,3 (2019): 180-187. doi: https://doi.org/10.1089/bioe.2019.0022
Hernandez-Resendiz I, Hartung F, Pardo LA. Antibodies Targeting K. Bioelectricity. 2019 Sep 01;1(3):180-187. doi: 10.1089/bioe.2019.0022. Epub 2019 Sep 16. PMID: 34471820; PMCID: PMC8370288.
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GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and K.

Frontiers in pharmacology

Abramavicius S, Petersen AG, Renaltan NS, Prat-Duran J, Torregrossa R, Stankevicius E, Whiteman M, Simonsen U.
PMID: 33841145
Front Pharmacol. 2021 Mar 26;12:613989. doi: 10.3389/fphar.2021.613989. eCollection 2021.

Donors of H

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Abramavicius S, Petersen AG, Renaltan NS, et al. GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and K. Front Pharmacol. 2021;12:613989doi: 10.3389/fphar.2021.613989.
Abramavicius, S., Petersen, A. G., Renaltan, N. S., Prat-Duran, J., Torregrossa, R., Stankevicius, E., Whiteman, M., & Simonsen, U. (2021). GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and K. Frontiers in pharmacology, 12613989. https://doi.org/10.3389/fphar.2021.613989
Abramavicius, Silvijus, et al. "GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and K." Frontiers in pharmacology vol. 12 (2021): 613989. doi: https://doi.org/10.3389/fphar.2021.613989
Abramavicius S, Petersen AG, Renaltan NS, Prat-Duran J, Torregrossa R, Stankevicius E, Whiteman M, Simonsen U. GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and K. Front Pharmacol. 2021 Mar 26;12:613989. doi: 10.3389/fphar.2021.613989. eCollection 2021. PMID: 33841145; PMCID: PMC8032876.
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Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits.

Frontiers in neuroanatomy

Datta D, Enwright JF, Arion D, Paspalas CD, Morozov YM, Lewis DA, Arnsten AFT.
PMID: 33328902
Front Neuroanat. 2020 Nov 20;14:578483. doi: 10.3389/fnana.2020.578483. eCollection 2020.

cAMP signaling has powerful, negative effects on cognitive functions of the primate dorsolateral prefrontal cortex (dlPFC), opening potassium channels to reduce firing and impair working memory, and increasing tau phosphorylation in aging neurons. This contrasts with cAMP actions in...

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Datta D, Enwright JF, Arion D, et al. Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits. Front Neuroanat. 2020;14:578483doi: 10.3389/fnana.2020.578483.
Datta, D., Enwright, J. F., Arion, D., Paspalas, C. D., Morozov, Y. M., Lewis, D. A., & Arnsten, A. F. T. (2020). Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits. Frontiers in neuroanatomy, 14578483. https://doi.org/10.3389/fnana.2020.578483
Datta, Dibyadeep, et al. "Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits." Frontiers in neuroanatomy vol. 14 (2020): 578483. doi: https://doi.org/10.3389/fnana.2020.578483
Datta D, Enwright JF, Arion D, Paspalas CD, Morozov YM, Lewis DA, Arnsten AFT. Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits. Front Neuroanat. 2020 Nov 20;14:578483. doi: 10.3389/fnana.2020.578483. eCollection 2020. PMID: 33328902; PMCID: PMC7714912.
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Alternative Targets for Modulators of Mitochondrial Potassium Channels.

Molecules (Basel, Switzerland)

Wrzosek A, Gałecka S, Żochowska M, Olszewska A, Kulawiak B.
PMID: 35011530
Molecules. 2022 Jan 04;27(1). doi: 10.3390/molecules27010299.

Mitochondrial potassium channels control potassium influx into the mitochondrial matrix and thus regulate mitochondrial membrane potential, volume, respiration, and synthesis of reactive oxygen species (ROS). It has been found that pharmacological activation of mitochondrial potassium channels during ischemia/reperfusion (I/R)...

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Wrzosek A, Gałecka S, Żochowska M, et al. Alternative Targets for Modulators of Mitochondrial Potassium Channels. Molecules. 2022;27(1)doi: 10.3390/molecules27010299.
Wrzosek, A., Gałecka, S., Żochowska, M., Olszewska, A., & Kulawiak, B. (2022). Alternative Targets for Modulators of Mitochondrial Potassium Channels. Molecules (Basel, Switzerland), 27(1), . https://doi.org/10.3390/molecules27010299
Wrzosek, Antoni, et al. "Alternative Targets for Modulators of Mitochondrial Potassium Channels." Molecules (Basel, Switzerland) vol. 27,1 (2022). doi: https://doi.org/10.3390/molecules27010299
Wrzosek A, Gałecka S, Żochowska M, Olszewska A, Kulawiak B. Alternative Targets for Modulators of Mitochondrial Potassium Channels. Molecules. 2022 Jan 04;27(1). doi: 10.3390/molecules27010299. PMID: 35011530; PMCID: PMC8746388.
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Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus.

iScience

Oulé M, Atucha E, Wells TM, Macharadze T, Sauvage MM, Kreutz MR, Lopez-Rojas J.
PMID: 34386734
iScience. 2021 Jul 16;24(8):102876. doi: 10.1016/j.isci.2021.102876. eCollection 2021 Aug 20.

The capacity to distinguish comparable experiences is fundamental for the recall of similar memories and has been proposed to require pattern separation in the dentate gyrus (DG). However, the cellular mechanisms by which mature granule cells (GCs) of the...

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Oulé M, Atucha E, Wells TM, et al. Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus. iScience. 2021;24(8):102876doi: 10.1016/j.isci.2021.102876.
Oulé, M., Atucha, E., Wells, T. M., Macharadze, T., Sauvage, M. M., Kreutz, M. R., & Lopez-Rojas, J. (2021). Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus. iScience, 24(8), 102876. https://doi.org/10.1016/j.isci.2021.102876
Oulé, Marie, et al. "Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus." iScience vol. 24,8 (2021): 102876. doi: https://doi.org/10.1016/j.isci.2021.102876
Oulé M, Atucha E, Wells TM, Macharadze T, Sauvage MM, Kreutz MR, Lopez-Rojas J. Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus. iScience. 2021 Jul 16;24(8):102876. doi: 10.1016/j.isci.2021.102876. eCollection 2021 Aug 20. PMID: 34386734; PMCID: PMC8346659.
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The Molecular Basis for the Calcium-Dependent Slow Afterhyperpolarization in CA1 Hippocampal Pyramidal Neurons.

Frontiers in physiology

Sahu G, Turner RW.
PMID: 35002757
Front Physiol. 2021 Dec 22;12:759707. doi: 10.3389/fphys.2021.759707. eCollection 2021.

Neuronal signal transmission depends on the frequency, pattern, and timing of spike output, each of which are shaped by spike afterhyperpolarizations (AHPs). There are classically three post-spike AHPs of increasing duration categorized as fast, medium and slow AHPs that...

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Sahu G, Turner RW. The Molecular Basis for the Calcium-Dependent Slow Afterhyperpolarization in CA1 Hippocampal Pyramidal Neurons. Front Physiol. 2021;12:759707doi: 10.3389/fphys.2021.759707.
Sahu, G., & Turner, R. W. (2021). The Molecular Basis for the Calcium-Dependent Slow Afterhyperpolarization in CA1 Hippocampal Pyramidal Neurons. Frontiers in physiology, 12759707. https://doi.org/10.3389/fphys.2021.759707
Sahu, Giriraj, and Turner, Ray W. "The Molecular Basis for the Calcium-Dependent Slow Afterhyperpolarization in CA1 Hippocampal Pyramidal Neurons." Frontiers in physiology vol. 12 (2021): 759707. doi: https://doi.org/10.3389/fphys.2021.759707
Sahu G, Turner RW. The Molecular Basis for the Calcium-Dependent Slow Afterhyperpolarization in CA1 Hippocampal Pyramidal Neurons. Front Physiol. 2021 Dec 22;12:759707. doi: 10.3389/fphys.2021.759707. eCollection 2021. PMID: 35002757; PMCID: PMC8730529.
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