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Showing 13 to 24 of 846 entries
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A standalone perfusion platform for drug testing and target validation in micro-vessel networks.

Biomicrofluidics

Zhang B, Peticone C, Murthy SK, Radisic M.
PMID: 24404058
Biomicrofluidics. 2013 Aug 26;7(4):44125. doi: 10.1063/1.4818837. eCollection 2013.

Studying the effects of pharmacological agents on human endothelium includes the routine use of cell monolayers cultivated in multi-well plates. This configuration fails to recapitulate the complex architecture of vascular networks in vivo and does not capture the relationship...

The long-term ingestion of a diet high in extra virgin olive oil produces obesity and insulin resistance but protects endothelial function in rats: a preliminary study.

Diabetology & metabolic syndrome

Keita H, Ramírez-San Juan E, Paniagua-Castro N, Garduño-Siciliano L, Quevedo L.
PMID: 24330822
Diabetol Metab Syndr. 2013 Sep 18;5(1):53. doi: 10.1186/1758-5996-5-53.

BACKGROUND: It has been hypothesized that fatty acids derived from a diet high in saturated fat may negatively affect endothelial function more significantly than a diet high in unsaturated fat; nevertheless, the effects of the long-term ingestion of monounsaturated...

Restoration of Endothelial Function in Pparα (-/-) Mice by Tempol.

PPAR research

Silswal N, Parelkar N, Andresen J, Wacker MJ.
PMID: 26649033
PPAR Res. 2015;2015:728494. doi: 10.1155/2015/728494. Epub 2015 Nov 15.

Peroxisome proliferator activated receptor alpha (PPARα) is one of the PPAR isoforms belonging to the nuclear hormone receptor superfamily that regulates genes involved in lipid and lipoprotein metabolism. PPARα is present in the vascular wall and is thought to...

Sustained Hypoxic Pulmonary Vasoconstriction in the Isolated Perfused Rat Lung: Effect of α1-adrenergic Receptor Agonist.

Iranian journal of medical sciences

Ketabchi F, Karimi Z, S Moosavi SM.
PMID: 24850985
Iran J Med Sci. 2014 May;39(3):275-81.

BACKGROUND: Alveolar hypoxia induces monophasic pulmonary vasoconstriction in vivo, biphasic vasoconstriction in the isolated pulmonary artery, and controversial responses in the isolated perfused lung. Pulmonary vascular responses to sustained alveolar hypoxia have not been addressed in the isolated perfused...

Anesthetic management for cesarean section in a patient with uncorrected double-outlet right ventricle.

SpringerPlus

Gu J, Cai Y, Liu B, Lv S.
PMID: 27069835
Springerplus. 2016 Apr 06;5:415. doi: 10.1186/s40064-016-2075-y. eCollection 2016.

BACKGROUND: We describe the anesthetic management for cesarean section in a pregnant woman with uncorrected double-outlet right ventricle. The anesthetic method, treatment of complications and lessons are discussed.CASE PRESENTATION: A 28-year-old woman visited our emergency room for progressive dyspnea...

Variable selection models based on multiple imputation with an application for predicting median effective dose and maximum effect.

Journal of statistical computation and simulation

Wan Y, Datta S, Conklin DJ, Kong M.
PMID: 26412909
J Stat Comput Simul. 2015;85(9):1902-1916. doi: 10.1080/00949655.2014.907801.

The statistical methods for variable selection and prediction could be challenging when missing covariates exist. Although multiple imputation (MI) is a universally accepted technique for solving missing data problem, how to combine the MI results for variable selection is...

Rats undernourished in utero have altered Ca2+ signaling and reduced fertility in adulthood.

Physiological reports

Muzi-Filho H, Souza AM, Bezerra CG, Boldrini LC, Takiya CM, Oliveira FL, Nesi RT, Valença SS, Silva AM, Zapata-Sudo G, Sudo RT, Einicker-Lamas M, Vieyra A, Lara LS, Cunha VM.
PMID: 26508737
Physiol Rep. 2015 Oct;3(10). doi: 10.14814/phy2.12587.

Epidemiological and animal studies have shown that placental undernutrition impairs reproduction in adult offspring, but the underlying molecular mechanisms within the male genital tract remain unknown. Due to its special physiological characteristics in transport and the modulation of the...

Vascular Dysfunction in Horses with Endocrinopathic Laminitis.

PloS one

Morgan RA, Keen JA, Walker BR, Hadoke PW.
PMID: 27684374
PLoS One. 2016 Sep 29;11(9):e0163815. doi: 10.1371/journal.pone.0163815. eCollection 2016.

Endocrinopathic laminitis (EL) is a vascular condition of the equine hoof resulting in severe lameness with both welfare and economic implications. EL occurs in association with equine metabolic syndrome and equine Cushing's disease. Vascular dysfunction, most commonly due to...

Catecholamines induce metamorphosis in the hydrozoan Halocordyle disticha but not in Hydractinia echinata.

Roux's archives of developmental biology : the official organ of the EDBO

Edwards NC, Thomas MB, Long BA, Amyotte SJ.
PMID: 28305639
Rouxs Arch Dev Biol. 1987 Sep;196(6):381-384. doi: 10.1007/BF00375776.

Planula larvae of the marine hydroids Halocordyle disticha and Hydractinia echinata were treated with the catecholamines epinephrine, norepinephrine and dopamine, as well as with certain of their precursors and agonists. Norepinephrine, L-dopa, dopamine and the dopamine agonist ADTN at...

Thoracic spinal anesthesia is safe for patients undergoing abdominal cancer surgery.

Anesthesia, essays and researches

Ellakany MH.
PMID: 25886230
Anesth Essays Res. 2014 May-Aug;8(2):223-8. doi: 10.4103/0259-1162.134516.

AIM: A double-blinded randomized controlled study to compare discharge time and patient satisfaction between two groups of patients submitted to open surgeries for abdominal malignancies using segmental thoracic spinal or general anesthesia.BACKGROUND: Open surgeries for abdominal malignancy are usually...

Chemical Composition and Vasorelaxant and Antispasmodic Effects of Essential Oil from Rosa indica L. Petals.

Evidence-based complementary and alternative medicine : eCAM

Rasheed HM, Khan T, Wahid F, Khan R, Shah AJ.
PMID: 26357519
Evid Based Complement Alternat Med. 2015;2015:279247. doi: 10.1155/2015/279247. Epub 2015 Aug 19.

Rosa indica L. belongs to the family Rosaceae and is locally known as gulaab. It has different traditional uses in cardiovascular and gastrointestinal disorders but there is no scientific data available in this regard. Therefore, the basic aim of...

Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation.

Journal of ophthalmology

Yu AY, Guo H, Wang QM, Bao FJ, Huang JH.
PMID: 26904274
J Ophthalmol. 2016;2016:4917659. doi: 10.1155/2016/4917659. Epub 2016 Jan 20.

Objective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation. Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled. To dilate pupil, one eye was randomly selected to receive intracamerally 1 mL...

Showing 13 to 24 of 846 entries