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Showing 61 to 69 of 69 entries
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Vascular responses after alpha adrenergic receptor blockade: II. Responses of venous and arterial segments to adrenergic stimulation in the forelimb of dog.

The Journal of clinical investigation

Abboud FM, Eckstein JW.
PMID: 16695932
J Clin Invest. 1968 Jan;47(1):10-9. doi: 10.1172/JCI105700.

The effects of nerve stimulation and of intraarterial injections of norepinephrine on arterial and venous resistances were studied in the perfused forelimb of dog before and after administration of the alpha adrenergic receptor blocker phenoxybenzamine.Pressures were recorded from the...

A rare cause of severe Cushing's syndrome.

Endocrinology, diabetes & metabolism case reports

Zaman S, Patel B, Glynne P, Vanderpump M, Alsafi A, Khan S, Flora R, Palazzo F, Wernig F.
PMID: 32168466
Endocrinol Diabetes Metab Case Rep. 2020 Mar 13;2020. doi: 10.1530/EDM-20-0011. Epub 2020 Mar 13.

SUMMARY: Ectopic adrenocorticotropic hormone (ACTH) production is an uncommon cause of Cushing's syndrome and, rarely, the source can be a phaeochromocytoma. A 55-year-old man presented following an episode of presumed gastroenteritis with vomiting and general malaise. Further episodes of...

Rupture of pheochromocytoma caused by phenoxybenzamine - A case report.

Urology case reports

Vasudeva Pai H.
PMID: 30009134
Urol Case Rep. 2018 Jul 06;20:70-71. doi: 10.1016/j.eucr.2018.07.005. eCollection 2018 Sep.

No abstract available.

Identification of diagnostic and prognostic biomarkers, and candidate targeted agents for hepatitis B virus-associated early stage hepatocellular carcinoma based on RNA-sequencing data.

Oncology letters

Zeng Z, Cao Z, Tang Y.
PMID: 32968453
Oncol Lett. 2020 Nov;20(5):231. doi: 10.3892/ol.2020.12094. Epub 2020 Sep 11.

Primary liver cancer is a rapidly progressing neoplasm with high morbidity and mortality rates. The present study aimed to identify potential diagnostic and prognostic biomarkers, and candidate targeted agents for hepatitis B virus (HBV)-associated early stage hepatocellular carcinoma (HCC)....

Double trouble: two cases of dual adrenal pathologies in one adrenal mass.

Endocrinology, diabetes & metabolism case reports

Chortis V, May CJH, Skordilis K, Ayuk J, Arlt W, Crowley RK.
PMID: 30909165
Endocrinol Diabetes Metab Case Rep. 2019 Mar 23;2019. doi: 10.1530/EDM-18-0151. Epub 2019 Mar 23.

Context Adrenal incidentalomas (AI) represent an increasingly common problem in modern endocrine practice. The diagnostic approach to AIs can be challenging and occasionally reveals surprising features. Here we describe two rare cases of complex adrenal lesions consisting of phaeochromocytomas...

Alpha-blockade during congenital heart surgery admissions: analysis from national database.

Cardiology in the young

Lee B, Villarreal EG, Mossad EB, Rausa J, Bronicki RA, Flores S, Loomba RS.
PMID: 34530952
Cardiol Young. 2021 Sep 17;1-7. doi: 10.1017/S1047951121003875. Epub 2021 Sep 17.

INTRODUCTION: The effects of alpha-blockade on haemodynamics during and following congenital heart surgery are well documented, but data on patient outcomes, mortality, and hospital charges are limited. The purpose of this study was to characterise the use of alpha-blockade...

Identification of Novel Kinase-Transcription Factor-mRNA-miRNA Regulatory Network in Nasopharyngeal Carcinoma by Bioinformatics Analysis.

International journal of general medicine

Gao L, Zhou L, Huang X.
PMID: 34744455
Int J Gen Med. 2021 Oct 30;14:7453-7469. doi: 10.2147/IJGM.S327657. eCollection 2021.

PURPOSE: Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors of the head and neck. This study aimed to investigate the crucial genes and regulatory networks involved in the carcinogenesis of NPC using a bioinformatics approach.METHODS: Five...

Standardization of the Rat Dorsal Random Pattern (McFarlane) Flap Model and Evaluation of the Pharmacological Agents Aiming to Salvage Partial Flap Necrosis: A Systematic Review and a Meta-analysis.

Annals of plastic surgery

Üstün GG, Öztürk S, Koçer U.
PMID: 34818287
Ann Plast Surg. 2021 Dec 01;87(6):e145-e152. doi: 10.1097/SAP.0000000000002919.

INTRODUCTION: Partial flap necrosis is a common complication after surgery. McFarlane flap model has been used for assessment of various agents' effects on random flap survival. The aim of this study was to review the methodology of studies using...

The numerical probability of carcinogenicity to humans of some pharmaceutical drugs: Alkylating agents, topoisomerase inhibitors or poisons, and DNA intercalators.

Fundamental & clinical pharmacology

Suarez-Torres JD, Orozco CA, Ciangherotti CE.
PMID: 33772863
Fundam Clin Pharmacol. 2021 Dec;35(6):1069-1089. doi: 10.1111/fcp.12674. Epub 2021 Apr 27.

The nonclinical branch of regulatory pharmacology has traditionally relied on the sensitivity and specificity of regulatorily recommended bioassays. Nonetheless, any predictive testing (eg, safety pharmacology) with less than 100% sensitivity or 100% specificity is prone to deliver false positive...

Showing 61 to 69 of 69 entries