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Showing 553 to 563 of 563 entries
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Pharmacological Medical Treatment of Epilepsy in Patients with Dementia: A Systematic Review.

Current Alzheimer research

Musaeus CS, Nilsson C, Cooper C, Kramberger MG, Verdelho A, Stefanova E, Religa D, Waldemar G, Frederiksen KS.
PMID: 34825872
Curr Alzheimer Res. 2021;18(9):689-694. doi: 10.2174/1567205018666211126121529.

BACKGROUND: Patients with dementia have an increased risk of developing epilepsy, especially in patients with vascular dementia and Alzheimer's disease. In selecting the optimal anti- epileptic drug (AED), the possible side effects such as drowsiness and worsening of cognitive...

Relevant pharmacological interactions between alkylating agents and antiepileptic drugs: Preclinical and clinical data.

Pharmacological research

Cucchiara F, Ferraro S, Luci G, Bocci G.
PMID: 34785318
Pharmacol Res. 2021 Nov 14;175:105976. doi: 10.1016/j.phrs.2021.105976. Epub 2021 Nov 14.

Seizures are relatively common in cancer patients, and co-administration of chemotherapeutic and antiepileptic drugs (AEDs) is highly probable and necessary in many cases. Nonetheless, clinically relevant interactions between chemotherapeutic drugs and AEDs are rarely summarized and pharmacologically described. These...

Status of epileptic spasms: A study of 21 children.

Epilepsy & behavior : E&B

Caraballo R, Semprino M, Fasulo L, Reyes G, Chacón S, Gallo A, Buompadre C.
PMID: 34864379
Epilepsy Behav. 2021 Dec 01;126:108451. doi: 10.1016/j.yebeh.2021.108451. Epub 2021 Dec 01.

OBJECTIVE: We studied cases with long-lasting epileptic spasms (ES) considered as a spasm status analyzing type of epilepsy, epileptic syndrome, etiology, treatment, and outcome in 21 patients.METHODS: We evaluated the charts of 21 patients seen between June 2006 and...

Relevant pharmacological interactions between alkylating agents and antiepileptic drugs: Preclinical and clinical data.

Pharmacological research

Cucchiara F, Ferraro S, Luci G, Bocci G.
PMID: 34785318
Pharmacol Res. 2021 Nov 14;175:105976. doi: 10.1016/j.phrs.2021.105976. Epub 2021 Nov 14.

Seizures are relatively common in cancer patients, and co-administration of chemotherapeutic and antiepileptic drugs (AEDs) is highly probable and necessary in many cases. Nonetheless, clinically relevant interactions between chemotherapeutic drugs and AEDs are rarely summarized and pharmacologically described. These...

Evaluation of diazepam as a drug treatment for water hemlock (Cicuta species) poisoning in Spanish goats.

Toxicon : official journal of the International Society on Toxinology

Green BT, Stonecipher CA, Welch KD, Lee ST, Cook D.
PMID: 34871669
Toxicon. 2022 Jan 15;205:79-83. doi: 10.1016/j.toxicon.2021.12.003. Epub 2021 Dec 03.

Water hemlocks (Cicuta spp.) are toxic members of the Apiaceae plant family. The best drug treatment for the convulsions associated with acute water hemlock poisoning in livestock and humans has not been determined experimentally. This work compared the therapeutic...

Relevant pharmacological interactions between alkylating agents and antiepileptic drugs: Preclinical and clinical data.

Pharmacological research

Cucchiara F, Ferraro S, Luci G, Bocci G.
PMID: 34785318
Pharmacol Res. 2021 Nov 14;175:105976. doi: 10.1016/j.phrs.2021.105976. Epub 2021 Nov 14.

Seizures are relatively common in cancer patients, and co-administration of chemotherapeutic and antiepileptic drugs (AEDs) is highly probable and necessary in many cases. Nonetheless, clinically relevant interactions between chemotherapeutic drugs and AEDs are rarely summarized and pharmacologically described. These...

Association between anti-seizure medication and outcomes in infants.

Journal of perinatology : official journal of the California Perinatal Association

Sewell EK, Hamrick SEG, Patel RM, Bennett M, Tolia VN, Ahmad KA.
PMID: 34671100
J Perinatol. 2021 Oct 20; doi: 10.1038/s41372-021-01240-1. Epub 2021 Oct 20.

OBJECTIVE: To compare treatment failure between: (1) infants treated with phenobarbital versus levetiracetam for first-line treatment and (2) infants treated with phenytoin versus levetiracetam for second-line treatment following phenobarbital.STUDY DESIGN: This retrospective cohort study included infants with seizures receiving...

Status of epileptic spasms: A study of 21 children.

Epilepsy & behavior : E&B

Caraballo R, Semprino M, Fasulo L, Reyes G, Chacón S, Gallo A, Buompadre C.
PMID: 34864379
Epilepsy Behav. 2021 Dec 01;126:108451. doi: 10.1016/j.yebeh.2021.108451. Epub 2021 Dec 01.

OBJECTIVE: We studied cases with long-lasting epileptic spasms (ES) considered as a spasm status analyzing type of epilepsy, epileptic syndrome, etiology, treatment, and outcome in 21 patients.METHODS: We evaluated the charts of 21 patients seen between June 2006 and...

Direct Comparison of the Lowest Effect Concentrations of Mutagenic Reference Substances in Two Ames Test Formats.

Toxics

Rainer B, Pinter E, Prielinger L, Coppola C, Marin-Kuan M, Schilter B, Apprich S, Tacker M.
PMID: 34209992
Toxics. 2021 Jun 29;9(7). doi: 10.3390/toxics9070152.

The Ames assay is the standard assay for identifying DNA-reactive genotoxic substances. Multiple formats are available and the correct choice of an assay protocol is essential for achieving optimal performance, including fit for purpose detection limits and required screening...

Novel Therapeutics for Neonatal Seizures.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Ziobro JM, Eschbach K, Shellhaas RA.
PMID: 34386906
Neurotherapeutics. 2021 Jul;18(3):1564-1581. doi: 10.1007/s13311-021-01085-8. Epub 2021 Aug 12.

Neonatal seizures are a common neurologic emergency for which therapies have not significantly changed in decades. Improvements in diagnosis and pathophysiologic understanding of the distinct features of acute symptomatic seizures and neonatal-onset epilepsies present exceptional opportunities for development of...

Relevant pharmacological interactions between alkylating agents and antiepileptic drugs: Preclinical and clinical data.

Pharmacological research

Cucchiara F, Ferraro S, Luci G, Bocci G.
PMID: 34785318
Pharmacol Res. 2022 Jan;175:105976. doi: 10.1016/j.phrs.2021.105976. Epub 2021 Nov 14.

Seizures are relatively common in cancer patients, and co-administration of chemotherapeutic and antiepileptic drugs (AEDs) is highly probable and necessary in many cases. Nonetheless, clinically relevant interactions between chemotherapeutic drugs and AEDs are rarely summarized and pharmacologically described. These...

Showing 553 to 563 of 563 entries