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Showing 13 to 24 of 563 entries
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Comparison on effects of phenobarbital and nicotine on nuclear protein synthesis in rat liver.

FEBS letters

Ruddon RW, Rainey CH.
PMID: 11945748
FEBS Lett. 1971 Apr 30;14(3):170-174. doi: 10.1016/0014-5793(71)80096-0.

No abstract available.

Neonatal Seizures.

Current treatment options in neurology

Painter MJ, Alvin J.
PMID: 11282039
Curr Treat Options Neurol. 2001 May;3(3):237-248. doi: 10.1007/s11940-001-0005-x.

Neonatal seizures are frequently manifested by subtle movements that are referable to brain stem structure, ie, nystagmus, conjugate eye movements, posturing, sucking movements, and so forth. Electroencephalogram (EEG) confirmation of abnormal movements is essential in diagnosing seizures in the...

Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor.

Nuclear receptor

Arnold KA, Eichelbaum M, Burk O.
PMID: 15043764
Nucl Recept. 2004 Mar 25;2(1):1. doi: 10.1186/1478-1336-2-1.

BACKGROUND: The constitutive androstane receptor (CAR) plays a key role in the control of drug metabolism and transport by mediating the phenobarbital-type induction of many phase I and II drug metabolizing enzymes and drug transporters. RESULTS: We identified transcripts...

Influence of phenobarbital treatment on the turnover of rat liver microsomal lipids.

FEBS letters

Eriksson LC, Dallner G.
PMID: 11946951
FEBS Lett. 1973 Feb 01;29(3):351-354. doi: 10.1016/0014-5793(73)80057-2.

No abstract available.

Inhibitory effect of nitric oxide on the metabolism of halogenated volatile anesthetics by cytochrome P-450.

Journal of anesthesia

Masaki E.
PMID: 14530945
J Anesth. 1999;13(2):83-9. doi: 10.1007/s005400050031.

PURPOSE: This study was undertaken to examine the effect of nitric oxide (NO) on the metabolism of halogenated volatile anesthetics (HVA) by cytochrome P-450 (CYP) under both aerobic and anaerobic conditions using rat hepatic microsomes.METHODS: A microsomal fraction was...

Effect of carbon monoxide and phenobarbital on hydroxylation of bile acids by rat liver microsomes.

FEBS letters

Einarsson K, Johansson G.
PMID: 11947176
FEBS Lett. 1969 Aug;4(3):177-180. doi: 10.1016/0014-5793(69)80228-0.

No abstract available.

Homogeneous immunoassay of phenobarbital by phase-resolved fluorescence spectroscopy.

Talanta

Bright FV, McGown LB.
PMID: 18963776
Talanta. 1985 Jan;32(1):15-8. doi: 10.1016/0039-9140(85)80006-0.

A new technique for determination of phenobarbital by homogeneous fluoroimmunoassay is described. Simultaneous determination of free and antibody-bound fluorescein-labelled phenobarbital is accomplished by making phase-resolved fluorescence measurements, in which selectivity is provided by the difference between the fluorescence lifetimes...

Characterization of insulin-like-growth factor II (IGF II) mRNA positive hepatic altered foci and IGF II expression in hepatocellular carcinoma during diethylnitrosamine-induced hepatocarcinogenesis in rats.

Journal of carcinogenesis

Mukherjee B, Ghosh S, Das T, Doloi M.
PMID: 16092956
J Carcinog. 2005 Aug 10;4:12. doi: 10.1186/1477-3163-4-12.

BACKGROUND: Insulin-like-growth factor II (IGF II) has been implicated in the pathogenesis of neoplasm of different tissues, including liver of rats and men. This growth factor is believed to exert its effect during cellular proliferation. During the process of...

Childhood epilepsy: Management in resource-limited setting.

Annals of Indian Academy of Neurology

Valvi C, Daga S, Kabade U, Agarwal M.
PMID: 19966976
Ann Indian Acad Neurol. 2008 Jan;11(1):33-6. doi: 10.4103/0972-2327.40223.

OBJECTIVE: To optimize the use of phenobarbital and/or phenytoin as frontline drugs for treatment of childhood epilepsy.DESIGN: Before-and -after study.SETTING: Epilepsy clinic at paediatric OPD, Sassoon General Hospital, Pune.MATERIALS AND METHODS: Epilepsy is a condition in which seizures are...

Effects of various inducers on the expression of cytochromes P-450 IIC8, 9, 10 and IIIA in cultured adult human hepatocytes.

Toxicology in vitro : an international journal published in association with BIBRA

Morel F, Beaune P, Ratanasavanh D, Flinois JP, Guengerich FP, Guillouzo A.
PMID: 20702214
Toxicol In Vitro. 1990;4(4):458-60. doi: 10.1016/0887-2333(90)90100-8.

Primary cultures of adult human hepatocytes were used to determine the capability of the human liver to respond to phenobarbital, 3-methylcholanthrene, troleandomycin and rifampicin, four compounds known to be potent inducers of hepatic cytochrome P-450 in various animal species....

The cytotoxicity of halothane in isolated hepatocytes: Evidence for two different mechanisms.

Toxicology in vitro : an international journal published in association with BIBRA

van Iersel AA, de Boer AJ, van Holsteijn CW, Blaauboer BJ.
PMID: 20702341
Toxicol In Vitro. 1988;2(2):75-81. doi: 10.1016/0887-2333(88)90017-3.

The effect of halothane on the functional properties of isolated hepatocytes was investigated. Glycogen levels and the oxygen consumption of hepatocytes, isolated from both control and phenobarbital-induced rats, decreased dose-dependently after exposure to halothane, irrespective of the oxygen concentration...

Enhanced sensitivity of perifused primary rat hepatocytes to mitogens and growth modulation by carcinogens.

Toxicology in vitro : an international journal published in association with BIBRA

Gebhardt R, Fischer S.
PMID: 20650111
Toxicol In Vitro. 1995 Aug;9(4):445-51. doi: 10.1016/0887-2333(95)00050-i.

Comparison of stationary cultivation (repeated changes of medium) with perifusion (continuous flow of medium) revealed that perifused hepatocytes show enhanced basal proliferation and are more sensitive to insulin and EGF. Similarly, the sensitivity of bromodeoxyuridine incorporation to inhibition by...

Showing 13 to 24 of 563 entries