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Showing 25 to 30 of 30 entries
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A case of the serotonin syndrome secondary to phenelzine monotherapy at therapeutic dosing.

Case reports in medicine

Malik A, Junglee N.
PMID: 25861278
Case Rep Med. 2015;2015:931963. doi: 10.1155/2015/931963. Epub 2015 Mar 16.

A 27-year-old Caucasian female with a history of depression was admitted to our local hospital with vague events that occurred a day before. This included an episode of dysarthria, and unsteadiness, followed by feeling generally unwell. Two weeks prior...

Transdermal selegiline for the treatment of major depressive disorder.

Neuropsychiatric disease and treatment

Lee KC, Chen JJ.
PMID: 19300583
Neuropsychiatr Dis Treat. 2007;3(5):527-37.

Non-selective inhibition of monoamine oxidase (MAO) enzymes (ie, isoforms A and B) in the brain are associated with clinically significant antidepressant effects. In the US, the selegiline transdermal system (STS; EMSAM) is the first antidepressant transdermal delivery system to...

MAO-inhibitors in Parkinson's Disease.

Experimental neurobiology

Riederer P, Laux G.
PMID: 22110357
Exp Neurobiol. 2011 Mar;20(1):1-17. doi: 10.5607/en.2011.20.1.1. Epub 2011 Mar 31.

Monoamine oxidase inhibitors (MAO-I) belong to the earliest drugs tried in Parkinson's disease (PD). They have been used with or without levodopa (L-DOPA). Non-selective MAO-I due to their side-effect/adverse reaction profile, like tranylcypromine have limited use in the treatment...

Administration of supplemental L-tyrosine with phenelzine: a clinical literature review.

Clinical pharmacology : advances and applications

Hinz M, Stein A, Cole T, Ryan P.
PMID: 25092999
Clin Pharmacol. 2014 Jul 22;6:107-10. doi: 10.2147/CPAA.S67271. eCollection 2014.

The subject of this literature review is the alleged relationship between L-tyrosine, phenelzine, and hypertensive crisis. Phenelzine (Nardil(®)) prescribing information notes: "The potentiation of sympathomimetic substances and related compounds by MAO inhibitors may result in hypertensive crises (see WARNINGS)....

Optimal treatment of social phobia: systematic review and meta-analysis.

Neuropsychiatric disease and treatment

Canton J, Scott KM, Glue P.
PMID: 22665997
Neuropsychiatr Dis Treat. 2012;8:203-15. doi: 10.2147/NDT.S23317. Epub 2012 May 03.

This article proposes a number of recommendations for the treatment of generalized social phobia, based on a systematic literature review and meta-analysis. An optimal treatment regimen would include a combination of medication and psychotherapy, along with an assertive clinical...

"Ping-pong gaze" secondary to monoamine oxidase inhibitor overdose.

Journal of pharmacology & pharmacotherapeutics

Attaway A, Sroujieh L, Mersfelder TL, Butler C, Ouellette D.
PMID: 27127395
J Pharmacol Pharmacother. 2016 Jan-Mar;7(1):34-7. doi: 10.4103/0976-500X.179360.

An infrequent manifestation of monoamine oxidase inhibitor (MAOI) toxicity is "ping-pong gaze" (PPG). We describe the case of a 26-year-old female who was found unresponsive after taking 40 tablets of phenelzine. On presentation to the hospital, her eyes were...

Showing 25 to 30 of 30 entries