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Showing 1513 to 1524 of 1539 entries
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Compounding and quality control of two pediatric topiramate pharmaceutical preparations.

Die Pharmazie

Mékidèche T, Curti C, Lamy E, Jean C, Peres PB, Vanelle P.
PMID: 33849699
Pharmazie. 2021 Apr 01;76(4):150-154. doi: 10.1691/ph.2021.0176.

In pediatric wards, topiramate is prescribed as an antiepileptic at non-licensed dosages. Compounding is the best way to obtain topiramate drug adapted to pediatric patients, but this practice requires to control the quality of batches and to manage a...

Simultaneous determination of sitagliptin and metformin in pharmaceutical preparations by capillary zone electrophoresis and its application to human plasma analysis.

Analytical chemistry insights

Salim M, El-Enany N, Belal F, Walash M, Patonay G.
PMID: 22904611
Anal Chem Insights. 2012;7:31-46. doi: 10.4137/ACI.S9940. Epub 2012 Jul 30.

A novel, quick, reliable and simple capillary zone electrophoresis CZE method was developed and validated for the simultaneous determination of sitagliptin (SG) and metformin (MF) in pharmaceutical preparations. Separation was carried out in fused silica capillary (50.0 cm total...

A Mobile Device App to Reduce Medication Errors and Time to Drug Delivery During Pediatric Cardiopulmonary Resuscitation: Study Protocol of a Multicenter Randomized Controlled Crossover Trial.

JMIR research protocols

Siebert JN, Ehrler F, Lovis C, Combescure C, Haddad K, Gervaix A, Manzano S.
PMID: 28830854
JMIR Res Protoc. 2017 Aug 22;6(8):e167. doi: 10.2196/resprot.7901.

BACKGROUND: During pediatric cardiopulmonary resuscitation (CPR), vasoactive drug preparation for continuous infusions is complex and time-consuming. The need for individual specific weight-based drug dose calculation and preparation places children at higher risk than adults for medication errors. Following an...

Medication Errors in Patients with Enteral Feeding Tubes in the Intensive Care Unit.

Journal of research in pharmacy practice

Sohrevardi SM, Jarahzadeh MH, Mirzaei E, Mirjalili M, Tafti AD, Heydari B.
PMID: 28616433
J Res Pharm Pract. 2017 Apr-Jun;6(2):100-105. doi: 10.4103/jrpp.JRPP_17_9.

OBJECTIVE: Most patients admitted to Intensive Care Units (ICU) have problems in using oral medication or ingesting solid forms of drugs. Selecting the most suitable dosage form in such patients is a challenge. The current study was conducted to...

Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue.

Experimental and therapeutic medicine

Karaarslan N, Yilmaz I, Sirin DY, Ozbek H, Kaplan N, Kaya YE, Akyuva Y, Gurbuz MS, Oznam K, Ates O.
PMID: 30112057
Exp Ther Med. 2018 Aug;16(2):1259-1265. doi: 10.3892/etm.2018.6289. Epub 2018 Jun 12.

The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clinicians, exert toxic effects on human primary nucleus pulposus (NP) and annulus fibrosis (AF). Primary...

Essential Medication Information for Patients: Ensuring Access.

Therapeutic innovation & regulatory science

Pearsall BM, Araojo R, Hinton D.
PMID: 30227511
Ther Innov Regul Sci. 2014 Mar;48(2):162-164. doi: 10.1177/2168479013507437.

The US Food and Drug Administration (FDA) is developing a new framework to provide patients with quality, up-to-date prescription product information that will promote the safe use of prescribed medication. The goal of this new Patient Medication Information is...

Qualitative and Quantitative Microbiological Studies of Paediatric Artemether-Lumefantrine Dry Powders and Paracetamol Syrups Obtained from Selected Drug Stores in Accra, Ghana.

Journal of tropical medicine

Opoku S, Nyanor I.
PMID: 31379951
J Trop Med. 2019 Jul 14;2019:7062016. doi: 10.1155/2019/7062016. eCollection 2019.

Infants and children under five years generally have high susceptibility to pathogenic and opportunistic infections due to immaturity and inexperience of their immune responses. The lives of these young children are threatened when they consume pharmaceutical preparations of poor...

Analysis of penicillamine using Cu-modified graphene quantum dots synthesized from uric acid as single precursor.

Journal of pharmaceutical analysis

Durán GM, Benavidez TE, Contento AM, Ríos A, García CD.
PMID: 29404056
J Pharm Anal. 2017 Oct;7(5):324-331. doi: 10.1016/j.jpha.2017.07.002. Epub 2017 Jul 06.

A simple methodology was developed to quantify penicillamine (PA) in pharmaceutical samples, using the selective interaction of the drug with Cu-modified graphene quantum dots (Cu-GQDs). The proposed strategy combines the advantages of carbon dots (over other nanoparticles) with the...

[Judicial recourse and access to health technologies: opportunities and risksJudicialização e acesso a tecnologias em saúde: oportunidades e riscos].

Revista panamericana de salud publica = Pan American journal of public health

Vidal J, Di Fabio YJL.
PMID: 31384265
Rev Panam Salud Publica. 2017 Dec 05;41:e137. doi: 10.26633/RPSP.2017.137. eCollection 2017.

Use of litigation to ensure and guarantee access to medical inputs constitutes one of the most effective strategies to ensure observance (or remedy the violation) of the right to health, often in relation to other fundamental human rights such...

Impact of Medical Conditions and Medications on Road Traffic Safety.

Oman medical journal

Chitme HR, Al-Kashmiri A, Al-Thehli HM, Al-Qanoobi MJ, Al-Mushefri MM, Venuvgopal J.
PMID: 30038731
Oman Med J. 2018 Jul;33(4):316-321. doi: 10.5001/omj.2018.58.

OBJECTIVES: Many medical conditions and medicines with therapeutic importance have been shown to impair driving skills, causing road traffic accidents, which leads to great human and economic suffering in Oman. The primary purpose of this study was to assess...

Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines.

American journal of translational research

Zgair A, Wong JC, Lee JB, Mistry J, Sivak O, Wasan KM, Hennig IM, Barrett DA, Constantinescu CS, Fischer PM, Gershkovich P.
PMID: 27648135
Am J Transl Res. 2016 Aug 15;8(8):3448-59. eCollection 2016.

There has been an escalating interest in the medicinal use of Cannabis sativa in recent years. Cannabis is often administered orally with fat-containing foods, or in lipid-based pharmaceutical preparations. However, the impact of lipids on the exposure of patients...

Specific features of rational pharmacotherapy in elderly patients.

European journal of hospital pharmacy : science and practice

Ermakov D, Fomina E, Kartashova O.
PMID: 34795002
Eur J Hosp Pharm. 2021 Nov 18; doi: 10.1136/ejhpharm-2021-002980. Epub 2021 Nov 18.

OBJECTIVE: It is well-known that finding an optimum medication at the correct dose for elderly patients is challenging for the practitioner. This study aimed to examine the main trends in prescribing medications for elderly patients and their compliance with...

Showing 1513 to 1524 of 1539 entries