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Showing 13 to 24 of 199 entries
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Influences of Dietary Added Sugar Consumption on Striatal Food-Cue Reactivity and Postprandial GLP-1 Response.

Frontiers in psychiatry

Dorton HM, Luo S, Monterosso JR, Page KA.
PMID: 29403396
Front Psychiatry. 2018 Jan 04;8:297. doi: 10.3389/fpsyt.2017.00297. eCollection 2017.

Sugar consumption in the United States exceeds recommendations from the American Heart Association. Overconsumption of sugar is linked to risk for obesity and metabolic disease. Animal studies suggest that high-sugar diets alter functions in brain regions associated with reward...

Binding of Natural Peptide Ligands to the Neuropeptide Y5 Receptor.

Angewandte Chemie (International ed. in English)

Rudolf S, Kaempf K, Vu O, Meiler J, Beck-Sickinger AG, Coin I.
PMID: 34822209
Angew Chem Int Ed Engl. 2021 Nov 25; doi: 10.1002/anie.202108738. Epub 2021 Nov 25.

The binding mode of natural peptide ligands to the Y 5 G protein-coupled receptor (Y 5 R), an attractive therapeutic target for the treatment of obesity, is largely unknown. Here, we apply complementary biochemical and computational approaches, including scanning...

Blood Sampling From Rat Ileal Mesenteric Vein Revealed a Major Role of Dietary Protein in Meal-Induced GLP-1 Response.

Frontiers in endocrinology

Hira T, Sekishita M, Hara H.
PMID: 34149624
Front Endocrinol (Lausanne). 2021 Jun 02;12:689685. doi: 10.3389/fendo.2021.689685. eCollection 2021.

The present study was conducted to examine region-dependent glucagon-like peptide-1 (GLP-1) responses to "meal ingestion" under physiological (conscious and unrestrained) conditions using rats with a catheter inserted into either the portal vein (PV) or the ileal mesenteric vein (ILMV)....

Anorexigenic Effects of Intermittent Hypoxia on the Gut-Brain Axis in Sleep Apnea Syndrome.

International journal of molecular sciences

Shobatake R, Ota H, Takahashi N, Ueno S, Sugie K, Takasawa S.
PMID: 35008784
Int J Mol Sci. 2021 Dec 29;23(1). doi: 10.3390/ijms23010364.

Sleep apnea syndrome (SAS) is a breathing disorder characterized by recurrent episodes of upper-airway collapse, resulting in intermittent hypoxia (IH) during sleep. Experimental studies with animals and cellular models have indicated that IH leads to attenuation of glucose-induced insulin...

The role of cholecystokinin and peptide YY in feed intake in Atlantic halibut (Hippoglossus hippoglossus) larvae.

Neuropeptides

Gomes AS, Lygre E, Harboe T, Zimmermann F, Jordal AO, Hamre K, Rønnestad I.
PMID: 34741845
Neuropeptides. 2021 Oct 28;91:102202. doi: 10.1016/j.npep.2021.102202. Epub 2021 Oct 28.

Control of appetite and feed intake in fish larvae are still largely unexplored. Two of the key players in controlling vertebrate's feed intake are cholecystokinin (CCK) and peptide YY (PYY). Here we investigated the mRNA expression of pyy, cck...

Effects of menstrual cycle on appetite-regulating hormones and energy intake in response to cycling exercise in physically active women.

Journal of applied physiology (Bethesda, Md. : 1985)

Kamemoto K, Yamada M, Matsuda T, Ogata H, Ishikawa A, Kanno M, Miyashita M, Sakamaki-Sunaga M.
PMID: 34882026
J Appl Physiol (1985). 2022 Jan 01;132(1):224-235. doi: 10.1152/japplphysiol.01117.2020. Epub 2021 Dec 09.

Although ample evidence supports the notion that an acute bout of endurance exercise performed at or greater than 70% of maximum oxygen uptake suppresses appetite partly through changes in appetite-regulating hormones, no study has directly compared the influence between...

Ligilactobacillus Salivarius LCK11 Prevents Obesity by Promoting PYY Secretion to Inhibit Appetite and Regulating Gut Microbiota in C57BL/6J Mice.

Molecular nutrition & food research

Liang C, Zhou XH, Jiao YH, Guo MJ, Meng L, Gong PM, Lyu LZ, Niu HY, Wu YF, Chen SW, Han X, Zhang LW.
PMID: 34272917
Mol Nutr Food Res. 2021 Sep;65(17):e2100136. doi: 10.1002/mnfr.202100136. Epub 2021 Jul 17.

SCOPE: Obesity is a common disease worldwide and there is an urgent need for strategies to preventing obesity.METHODS AND RESULTS: The anti-obesity effect and mechanism of Ligilactobacillus salivarius LCK11 (LCK11) is studied using a C57BL/6J male mouse model in...

Peptide-YY.

Molecular metabolism

Boland BB, Laker RC, O'Brien S, Sitaula S, Sermadiras I, Nielsen JC, Barkholt P, Roostalu U, Hecksher-Sørensen J, Sejthen SR, Thorbek DD, Suckow A, Burmeister N, Oldham S, Will S, Howard VG, Gill BM, Newton P, Naylor J, Hornigold DC, Austin J, Lantier L, McGuinness OP, Trevaskis JL, Grimsby JS, Rhodes CJ.
PMID: 34781035
Mol Metab. 2021 Nov 12;101392. doi: 10.1016/j.molmet.2021.101392. Epub 2021 Nov 12.

OBJECTIVE: Obesity-linked type 2 diabetes (T2D) is a worldwide health concern and many novel approaches are being considered for its treatment and subsequent prevention of serious comorbidities. Co-administration of glucagon like peptide 1 (Fc-GLP-1) and peptide YYMETHODS: In this...

Effect of inulin-type fructans on appetite in patients with type 2 diabetes: a randomised controlled crossover trial.

Journal of nutritional science

Birkeland E, Gharagozlian S, Birkeland KI, Holm OKS, Thorsby PM, Aas AM.
PMID: 34589204
J Nutr Sci. 2021 Sep 10;10:e72. doi: 10.1017/jns.2021.70. eCollection 2021.

The aim of the study was to investigate the effect of prebiotic fibres on appetite-regulating hormones, subjective feeling of appetite and energy intake in subjects with type 2 diabetes. Data presented are secondary outcomes of a study investigating the...

Pleurotus eryngii improves postprandial glycaemia, hunger and fullness perception, and enhances ghrelin suppression in people with metabolically unhealthy obesity.

Pharmacological research

Kleftaki SA, Simati S, Amerikanou C, Gioxari A, Tzavara C, Zervakis GI, Kalogeropoulos N, Kokkinos A, Kaliora AC.
PMID: 34798266
Pharmacol Res. 2021 Nov 16;175:105979. doi: 10.1016/j.phrs.2021.105979. Epub 2021 Nov 16.

The aim of this study was to examine potential postprandial benefits of Pleurotus eryngii in nineteen volunteers with metabolically unhealthy obesity. An acute, randomized, crossover-designed trial comparing a meal with Pleurotus eryngii and a control meal was performed. The...

Enterohormone therapy for short bowel syndrome.

Current opinion in endocrinology, diabetes, and obesity

Verbiest A, Wauters L, Vanuytsel T, Storm V, Reinwand DA.
PMID: 35034035
Curr Opin Endocrinol Diabetes Obes. 2022 Jan 14; doi: 10.1097/MED.0000000000000710. Epub 2022 Jan 14.

PURPOSE OF THIS REVIEW: Short bowel syndrome (SBS) patients are at risk to develop intestinal failure when the decreased absorption of macronutrients, water, and electrolytes necessitates parenteral support for survival. The adverse effects of SBS and parenteral support negatively...

Pleurotus eryngii improves postprandial glycaemia, hunger and fullness perception, and enhances ghrelin suppression in people with metabolically unhealthy obesity.

Pharmacological research

Kleftaki SA, Simati S, Amerikanou C, Gioxari A, Tzavara C, Zervakis GI, Kalogeropoulos N, Kokkinos A, Kaliora AC.
PMID: 34798266
Pharmacol Res. 2021 Nov 16;175:105979. doi: 10.1016/j.phrs.2021.105979. Epub 2021 Nov 16.

The aim of this study was to examine potential postprandial benefits of Pleurotus eryngii in nineteen volunteers with metabolically unhealthy obesity. An acute, randomized, crossover-designed trial comparing a meal with Pleurotus eryngii and a control meal was performed. The...

Showing 13 to 24 of 199 entries