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Correction: Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo.

PloS one

Nirvanappa AC, Mohan CD, Rangappa S, Ananda H, Sukhorukov AY, Shanmugam MK, Sundaram MS, Nayaka SC, Girish KS, Chinnathambi A, Zayed ME, Alharbi SA, Sethi G, Basappa, Rangappa KS.
PMID: 28384360
PLoS One. 2017 Apr 06;12(4):e0175659. doi: 10.1371/journal.pone.0175659. eCollection 2017.

[This corrects the article DOI: 10.1371/journal.pone.0163209.].

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Nirvanappa AC, Mohan CD, Rangappa S, et al. Correction: Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo. PLoS One. 2017;12(4):e0175659doi: 10.1371/journal.pone.0175659.
Nirvanappa, A. C., Mohan, C. D., Rangappa, S., Ananda, H., Sukhorukov, A. Y., Shanmugam, M. K., Sundaram, M. S., Nayaka, S. C., Girish, K. S., Chinnathambi, A., Zayed, M. E., Alharbi, S. A., Sethi, G., Basappa, & Rangappa, K. S. (2017). Correction: Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo. PloS one, 12(4), e0175659. https://doi.org/10.1371/journal.pone.0175659
Nirvanappa, Anilkumar C, et al. "Correction: Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo." PloS one vol. 12,4 (2017): e0175659. doi: https://doi.org/10.1371/journal.pone.0175659
Nirvanappa AC, Mohan CD, Rangappa S, Ananda H, Sukhorukov AY, Shanmugam MK, Sundaram MS, Nayaka SC, Girish KS, Chinnathambi A, Zayed ME, Alharbi SA, Sethi G, Basappa, Rangappa KS. Correction: Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo. PLoS One. 2017 Apr 06;12(4):e0175659. doi: 10.1371/journal.pone.0175659. eCollection 2017. PMID: 28384360; PMCID: PMC5383341.
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Rh(II)/Mg(O.

Organic letters

Ko YO, Jeon HJ, Jung DJ, Kim UB, Lee SG.
PMID: 27978637
Org Lett. 2016 Dec 16;18(24):6432-6435. doi: 10.1021/acs.orglett.6b03328. Epub 2016 Dec 01.

A novel, one-pot route for the synthesis of nonaromatic ring-fused 1,4-oxazepines and 1,4-oxazines has been developed. The reaction features a sequential rhodium(II)-catalyzed reaction of N-sulfonyl-1,2,3-triazoles with glycidols, followed by a regioselective Lewis acid Mg(O

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Ko YO, Jeon HJ, Jung DJ, et al. Rh(II)/Mg(O. Org Lett. 2016;18(24):6432-6435doi: 10.1021/acs.orglett.6b03328.
Ko, Y. O., Jeon, H. J., Jung, D. J., Kim, U. B., & Lee, S. G. (2016). Rh(II)/Mg(O. Organic letters, 18(24), 6432-6435. https://doi.org/10.1021/acs.orglett.6b03328
Ko, Young Ok, et al. "Rh(II)/Mg(O." Organic letters vol. 18,24 (2016): 6432-6435. doi: https://doi.org/10.1021/acs.orglett.6b03328
Ko YO, Jeon HJ, Jung DJ, Kim UB, Lee SG. Rh(II)/Mg(O. Org Lett. 2016 Dec 16;18(24):6432-6435. doi: 10.1021/acs.orglett.6b03328. Epub 2016 Dec 01. PMID: 27978637.
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Reaction of phosphinylated nitrosoalkenes with electron-rich heterocycles. Electrophilic aromatic substitution vs. cycloaddition.

Organic & biomolecular chemistry

de Los Santos JM, Rubiales G, Sbai ZE, Ochoa de Retana AM, Palacios F.
PMID: 27976778
Org Biomol Chem. 2017 Jan 18;15(3):662-671. doi: 10.1039/c6ob02486f.

The behavior of phosphinyl nitrosoalkenes with indole, pyrrole and 2,5-dimethylpyrrole is described. The reaction of nitrosoalkenes with indole leads to the formation of 3-substituted indoles. While a concerted asynchronous [4 + 2] cycloaddition process may explain the formation of...

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de Los Santos JM, Rubiales G, Sbai ZE, et al. Reaction of phosphinylated nitrosoalkenes with electron-rich heterocycles. Electrophilic aromatic substitution vs. cycloaddition. Org Biomol Chem. 2017;15(3):662-671doi: 10.1039/c6ob02486f.
de Los Santos, J. M., Rubiales, G., Sbai, Z. E., Ochoa de Retana, A. M., & Palacios, F. (2017). Reaction of phosphinylated nitrosoalkenes with electron-rich heterocycles. Electrophilic aromatic substitution vs. cycloaddition. Organic & biomolecular chemistry, 15(3), 662-671. https://doi.org/10.1039/c6ob02486f
de Los Santos, Jesús M, et al. "Reaction of phosphinylated nitrosoalkenes with electron-rich heterocycles. Electrophilic aromatic substitution vs. cycloaddition." Organic & biomolecular chemistry vol. 15,3 (2017): 662-671. doi: https://doi.org/10.1039/c6ob02486f
de Los Santos JM, Rubiales G, Sbai ZE, Ochoa de Retana AM, Palacios F. Reaction of phosphinylated nitrosoalkenes with electron-rich heterocycles. Electrophilic aromatic substitution vs. cycloaddition. Org Biomol Chem. 2017 Jan 18;15(3):662-671. doi: 10.1039/c6ob02486f. PMID: 27976778.
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3,4-Dihydro-1,3-oxazines from Dcycloheexylcarbodiimide.

Journal of medicinal chemistry

May EL.
PMID: 22185171
J Med Chem. 1967 May 01;10(3):505-6. doi: 10.1021/jm00315a055.

No abstract available.

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May EL. 3,4-Dihydro-1,3-oxazines from Dcycloheexylcarbodiimide. J Med Chem. 1967;10(3):505-6doi: 10.1021/jm00315a055.
May, E. L. (1967). 3,4-Dihydro-1,3-oxazines from Dcycloheexylcarbodiimide. Journal of medicinal chemistry, 10(3), 505-6. https://doi.org/10.1021/jm00315a055
May, E L. "3,4-Dihydro-1,3-oxazines from Dcycloheexylcarbodiimide." Journal of medicinal chemistry vol. 10,3 (1967): 505-6. doi: https://doi.org/10.1021/jm00315a055
May EL. 3,4-Dihydro-1,3-oxazines from Dcycloheexylcarbodiimide. J Med Chem. 1967 May 01;10(3):505-6. doi: 10.1021/jm00315a055. PMID: 22185171.
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The Elusive Seven-Membered Cyclic Imino Ether Tetrahydrooxazepine.

Journal of the American Chemical Society

Verbraeken B, Hullaert J, van Guyse J, Van Hecke K, Winne J, Hoogenboom R.
PMID: 30508478
J Am Chem Soc. 2018 Dec 19;140(50):17404-17408. doi: 10.1021/jacs.8b10918. Epub 2018 Dec 10.

Cyclic imino ether heterocycles are used as ligands in transition metal catalysis, in various drugs and as reactive monomers in living cationic ring-opening polymerization (CROP). While five- and six-membered cyclic imino ethers, i.e. 2-oxazolines and 4,5-dihydro-1,3-oxazines, have extensively been...

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Verbraeken B, Hullaert J, van Guyse J, et al. The Elusive Seven-Membered Cyclic Imino Ether Tetrahydrooxazepine. J Am Chem Soc. 2018;140(50):17404-17408doi: 10.1021/jacs.8b10918.
Verbraeken, B., Hullaert, J., van Guyse, J., Van Hecke, K., Winne, J., & Hoogenboom, R. (2018). The Elusive Seven-Membered Cyclic Imino Ether Tetrahydrooxazepine. Journal of the American Chemical Society, 140(50), 17404-17408. https://doi.org/10.1021/jacs.8b10918
Verbraeken, Bart, et al. "The Elusive Seven-Membered Cyclic Imino Ether Tetrahydrooxazepine." Journal of the American Chemical Society vol. 140,50 (2018): 17404-17408. doi: https://doi.org/10.1021/jacs.8b10918
Verbraeken B, Hullaert J, van Guyse J, Van Hecke K, Winne J, Hoogenboom R. The Elusive Seven-Membered Cyclic Imino Ether Tetrahydrooxazepine. J Am Chem Soc. 2018 Dec 19;140(50):17404-17408. doi: 10.1021/jacs.8b10918. Epub 2018 Dec 10. PMID: 30508478.
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Evaluation of the Antioxidant Activity of .

Antioxidants (Basel, Switzerland)

Firpo G, Ramírez ML, Faillace MS, de Brito MDRM, E Silva APSCL, Costa JP, Rodríguez MC, Argüello GA, Szakonyi Z, Fülöp F, Peláez WJ.
PMID: 31242617
Antioxidants (Basel). 2019 Jun 25;8(6). doi: 10.3390/antiox8060197.

The growing interest in the chemistry of unsaturated ring-fused 1,3-heterocycles, in this particular case 1,3-oxazines, arise in part from their versatile pharmacological applications. In the present article, the evaluation of the in vitro and ex vivo antioxidant activity of...

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Firpo G, Ramírez ML, Faillace MS, et al. Evaluation of the Antioxidant Activity of . Antioxidants (Basel). 2019;8(6)doi: 10.3390/antiox8060197.
Firpo, G., Ramírez, M. L., Faillace, M. S., de Brito, M. D. R. M., E Silva, A. P. S. C. L., Costa, J. P., Rodríguez, M. C., Argüello, G. A., Szakonyi, Z., Fülöp, F., & Peláez, W. J. (2019). Evaluation of the Antioxidant Activity of . Antioxidants (Basel, Switzerland), 8(6), . https://doi.org/10.3390/antiox8060197
Firpo, Guadalupe, et al. "Evaluation of the Antioxidant Activity of ." Antioxidants (Basel, Switzerland) vol. 8,6 (2019). doi: https://doi.org/10.3390/antiox8060197
Firpo G, Ramírez ML, Faillace MS, de Brito MDRM, E Silva APSCL, Costa JP, Rodríguez MC, Argüello GA, Szakonyi Z, Fülöp F, Peláez WJ. Evaluation of the Antioxidant Activity of . Antioxidants (Basel). 2019 Jun 25;8(6). doi: 10.3390/antiox8060197. PMID: 31242617; PMCID: PMC6616633.
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DFT study of structural and electronic properties of 1,4-diarylcyclopenta[d] pyridazines and oxazines for non-linear optical applications.

Journal of molecular modeling

Wild S, Tice N.
PMID: 33517540
J Mol Model. 2021 Jan 31;27(2):60. doi: 10.1007/s00894-021-04676-6.

Polymer and molecular-based electronic materials incorporating heterocycles like thiophenes and pyrroles are attractive possibilities as substitutes for semimetal materials. Heterocyclic materials are heavily studied in this regard due to the large variations in possible substrates. Herein we evaluated four...

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Wild S, Tice N. DFT study of structural and electronic properties of 1,4-diarylcyclopenta[d] pyridazines and oxazines for non-linear optical applications. J Mol Model. 2021;27(2):60doi: 10.1007/s00894-021-04676-6.
Wild, S., & Tice, N. (2021). DFT study of structural and electronic properties of 1,4-diarylcyclopenta[d] pyridazines and oxazines for non-linear optical applications. Journal of molecular modeling, 27(2), 60. https://doi.org/10.1007/s00894-021-04676-6
Wild, Steven, and Tice, Nathan. "DFT study of structural and electronic properties of 1,4-diarylcyclopenta[d] pyridazines and oxazines for non-linear optical applications." Journal of molecular modeling vol. 27,2 (2021): 60. doi: https://doi.org/10.1007/s00894-021-04676-6
Wild S, Tice N. DFT study of structural and electronic properties of 1,4-diarylcyclopenta[d] pyridazines and oxazines for non-linear optical applications. J Mol Model. 2021 Jan 31;27(2):60. doi: 10.1007/s00894-021-04676-6. PMID: 33517540.
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Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives.

Mini reviews in medicinal chemistry

Farghaly TA, Dawood KM.
PMID: 34967287
Mini Rev Med Chem. 2021 Dec 29; doi: 10.2174/1389557522666211229114446. Epub 2021 Dec 29.

Despite several reports and reviews addressing the biological significance of pyrazoles and oxazines, no comprehensive work on the pyrazolo oxazine fused ring system has been published so far.We report all biological evaluations on pyrazolo-oxazine derivatives in this mini-review to...

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Farghaly TA, Dawood KM. Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives. Mini Rev Med Chem. 2021;doi: 10.2174/1389557522666211229114446.
Farghaly, T. A., & Dawood, K. M. (2021). Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives. Mini reviews in medicinal chemistry, . https://doi.org/10.2174/1389557522666211229114446
Farghaly, Thoraya A, and Dawood, Kamal M. "Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives." Mini reviews in medicinal chemistry vol. (2021). doi: https://doi.org/10.2174/1389557522666211229114446
Farghaly TA, Dawood KM. Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives. Mini Rev Med Chem. 2021 Dec 29; doi: 10.2174/1389557522666211229114446. Epub 2021 Dec 29. PMID: 34967287.
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Imidates: an emerging synthon for N-heterocycles.

Organic & biomolecular chemistry

Thakur R, Jaiswal Y, Kumar A.
PMID: 31720673
Org Biomol Chem. 2019 Nov 27;17(46):9829-9843. doi: 10.1039/c9ob01899a.

The unique electronic reactivity of imidates has been recently exploited for the syntheses of diverse classes of N-heterocycles via C-N annulation reactions under acid/base/metal-catalyzed/radical-mediated reaction conditions. As opposed to amides, the imidate functionality provides both electrophilic and nucleophilic centers...

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Thakur R, Jaiswal Y, Kumar A. Imidates: an emerging synthon for N-heterocycles. Org Biomol Chem. 2019;17(46):9829-9843doi: 10.1039/c9ob01899a.
Thakur, R., Jaiswal, Y., & Kumar, A. (2019). Imidates: an emerging synthon for N-heterocycles. Organic & biomolecular chemistry, 17(46), 9829-9843. https://doi.org/10.1039/c9ob01899a
Thakur, Rima, et al. "Imidates: an emerging synthon for N-heterocycles." Organic & biomolecular chemistry vol. 17,46 (2019): 9829-9843. doi: https://doi.org/10.1039/c9ob01899a
Thakur R, Jaiswal Y, Kumar A. Imidates: an emerging synthon for N-heterocycles. Org Biomol Chem. 2019 Nov 27;17(46):9829-9843. doi: 10.1039/c9ob01899a. PMID: 31720673.
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Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes.

Organic & biomolecular chemistry

Chada RR, Kajare RC, Bhandari MC, Mohammed SZ, Khatravath M, Warudikar K, Punna N.
PMID: 33403372
Org Biomol Chem. 2021 Jan 28;19(4):809-821. doi: 10.1039/d0ob02279a. Epub 2021 Jan 06.

An efficient approach for the highly diastereoselective construction of functionalized cyclopenta[d][1,2]oxazines via sequential oxyamination and Pauson-Khand reaction of readily accessible propargylic alcohols has been developed. Furthermore, the ring closing metathesis of these N-O linked 1,7-enynes afforded vinylated-[1,2]oxazines in good...

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Chada RR, Kajare RC, Bhandari MC, et al. Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes. Org Biomol Chem. 2021;19(4):809-821doi: 10.1039/d0ob02279a.
Chada, R. R., Kajare, R. C., Bhandari, M. C., Mohammed, S. Z., Khatravath, M., Warudikar, K., & Punna, N. (2021). Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes. Organic & biomolecular chemistry, 19(4), 809-821. https://doi.org/10.1039/d0ob02279a
Chada, Raji Reddy, et al. "Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes." Organic & biomolecular chemistry vol. 19,4 (2021): 809-821. doi: https://doi.org/10.1039/d0ob02279a
Chada RR, Kajare RC, Bhandari MC, Mohammed SZ, Khatravath M, Warudikar K, Punna N. Facile access to [1,2]-oxazine derivatives via annulations of aminoxy-tethered 1,7-enynes. Org Biomol Chem. 2021 Jan 28;19(4):809-821. doi: 10.1039/d0ob02279a. Epub 2021 Jan 06. PMID: 33403372.
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Microwave-Assisted Synthesis of 2-Aryl-2-oxazolines, 5,6-Dihydro-4H-1,3-oxazines, and 4,5,6,7-Tetrahydro-1,3-oxazepines.

Organic letters

Mollo MC, Orelli LR.
PMID: 27934376
Org Lett. 2016 Dec 02;18(23):6116-6119. doi: 10.1021/acs.orglett.6b03122. Epub 2016 Nov 22.

The first general procedure for the synthesis of 5- to 7-membered cyclic iminoethers by microwave-assisted cyclization of ω-amido alcohols promoted by polyphosphoric acid (PPA) esters is presented. 2-Aryl-2-oxazolines and 5,6-dihydro-4H-1,3-oxazines were efficiently prepared using ethyl polyphosphate/CHCl

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Mollo MC, Orelli LR. Microwave-Assisted Synthesis of 2-Aryl-2-oxazolines, 5,6-Dihydro-4H-1,3-oxazines, and 4,5,6,7-Tetrahydro-1,3-oxazepines. Org Lett. 2016;18(23):6116-6119doi: 10.1021/acs.orglett.6b03122.
Mollo, M. C., & Orelli, L. R. (2016). Microwave-Assisted Synthesis of 2-Aryl-2-oxazolines, 5,6-Dihydro-4H-1,3-oxazines, and 4,5,6,7-Tetrahydro-1,3-oxazepines. Organic letters, 18(23), 6116-6119. https://doi.org/10.1021/acs.orglett.6b03122
Mollo, María C, and Orelli, Liliana R. "Microwave-Assisted Synthesis of 2-Aryl-2-oxazolines, 5,6-Dihydro-4H-1,3-oxazines, and 4,5,6,7-Tetrahydro-1,3-oxazepines." Organic letters vol. 18,23 (2016): 6116-6119. doi: https://doi.org/10.1021/acs.orglett.6b03122
Mollo MC, Orelli LR. Microwave-Assisted Synthesis of 2-Aryl-2-oxazolines, 5,6-Dihydro-4H-1,3-oxazines, and 4,5,6,7-Tetrahydro-1,3-oxazepines. Org Lett. 2016 Dec 02;18(23):6116-6119. doi: 10.1021/acs.orglett.6b03122. Epub 2016 Nov 22. PMID: 27934376.
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Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines.

International journal of medicinal chemistry

Belz T, Ihmaid S, Al-Rawi J, Petrovski S.
PMID: 25374690
Int J Med Chem. 2013;2013:436397. doi: 10.1155/2013/436397. Epub 2013 Oct 31.

New N-(benzyl carbamothioyl)-2-hydroxy substituted benzamides 13, 20, and 21 were synthesized using sodium bicarbonate and benzyl amine with 2-thioxo-substituted-1,3-benzoxazines 6, 10a, b, 11c, and 12a-n. The 2-thioxo-substituted-1,3-oxazines 6, 10a-b, 11d 12a-n, and 26 were converted to the corresponding 2-methylthio-substituted-1,3-oxazines...

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Belz T, Ihmaid S, Al-Rawi J, et al. Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines. Int J Med Chem. 2013;2013:436397doi: 10.1155/2013/436397.
Belz, T., Ihmaid, S., Al-Rawi, J., & Petrovski, S. (2013). Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines. International journal of medicinal chemistry, 2013436397. https://doi.org/10.1155/2013/436397
Belz, Tyson, et al. "Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines." International journal of medicinal chemistry vol. 2013 (2013): 436397. doi: https://doi.org/10.1155/2013/436397
Belz T, Ihmaid S, Al-Rawi J, Petrovski S. Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines. Int J Med Chem. 2013;2013:436397. doi: 10.1155/2013/436397. Epub 2013 Oct 31. PMID: 25374690; PMCID: PMC4207449.
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Showing 13 to 24 of 114 entries