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Showing 1105 to 1115 of 1115 entries
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Human gingiva-derived mesenchymal stem cells promote osteogenic differentiation through their immunosuppressive function.

Journal of oral biosciences

Zhao J, Liu R, Zhu J, Chen S, Xu L.
PMID: 34284117
J Oral Biosci. 2021 Jul 17; doi: 10.1016/j.job.2021.07.003. Epub 2021 Jul 17.

OBJECTIVES: Human gingiva-derived mesenchymal stem cells (GMSCs) have emerged as a new MSC population exhibiting robust immune regulatory functions, multipotent differentiation potential, and regenerative ability. However, the effects of GMSCs on T cells remain unexplored. Herein, we aimed to...

The Evaluation of AREG, MMP-2, CHI3L1, GFAP, and OPN Serum Combined Value in Astrocytic Glioma Patients' Diagnosis and Prognosis.

Brain sciences

Urbanavičiūtė R, Skauminas K, Skiriutė D.
PMID: 33227903
Brain Sci. 2020 Nov 19;10(11). doi: 10.3390/brainsci10110872.

Gliomas account for approximately 70% of primary brain tumors in adults. Of all gliomas, grade IV astrocytoma, also called glioblastoma, has the poorest overall survival, with

Long-Term Treatment of Azathioprine in Rats Induces Vessel Mineralization.

Biomedicines

Schuchardt M, Herrmann J, Henkel C, Babic M, van der Giet M, Tölle M.
PMID: 33806932
Biomedicines. 2021 Mar 23;9(3). doi: 10.3390/biomedicines9030327.

Medial vascular calcification (mVC) is closely related to cardiovascular disease, especially in patients suffering from chronic kidney disease (CKD). Even after successful kidney transplantation, cardiovascular mortality remains increased. There is evidence that immunosuppressive drugs might influence pathophysiological mechanisms in...

Silica nanoparticle-modified microcomb electrode for voltammetry detection of osteopontin with high sensitivity.

Biotechnology and applied biochemistry

Shu H, Zhao L, Li X, Gong J, Yin G, Chen H.
PMID: 34423464
Biotechnol Appl Biochem. 2021 Aug 22; doi: 10.1002/bab.2242. Epub 2021 Aug 22.

Osteosarcoma is a commonly occurring bone malignancy, and it is the second most common cause of cancer deaths in adolescents and children. A sensitive silica nanoparticle (Si-NP) modified current-volt sensor was introduced to identify the osteopontin antigen, a well-known...

Downregulation of inflammatory mediators by ethanolic extract of Bergenia ligulata (Wall.) in oxalate injured renal epithelial cells.

Journal of ethnopharmacology

Singh A, Tandon S, Nandi SP, Kaur T, Tandon C.
PMID: 33836258
J Ethnopharmacol. 2021 Jul 15;275:114104. doi: 10.1016/j.jep.2021.114104. Epub 2021 Apr 06.

ETHNOPHARMACOLOGICAL RELEVANCE: In the Indian traditional system of medicine, Bergenia ligulata (Wall.) Engl. has been used for treatment of urolithiasis. Its efficacious nature has led to its incorporation in various commercial herbal formulations such as Cystone and Neeri which...

Histologic and Immunohistochemical Assessment of the Effect of Various Biomaterials on New Bone Formation in the Maxillary Sinus Floor Augmentation Procedure.

The International journal of oral & maxillofacial implants

Gülcan H, Gülşen U, Billur D, Bayram P, Dereci Ö.
PMID: 34919604
Int J Oral Maxillofac Implants. 2021 Nov-Dec;36(6):1076-1087. doi: 10.11607/jomi.8928.

PURPOSE: To assess the effect of different kinds of biomaterials placed with maxillary sinus floor augmentation (MSFA) on bone regeneration.MATERIALS AND METHODS: Thirty-six New Zealand rabbits were used in the study. A standardized method of surgical approach was used...

DEFICIENCY OF MYELOID PHD PROTEINS AGGRAVATES ATHEROGENESIS VIA MACROPHAGE APOPTOSIS AND PARACRINE FIBROTIC SIGNALING: Atherogenic effects of myeloid PHD knockdown.

Cardiovascular research

van Kuijk K, Demandt JAF, Perales-Patón J, Theelen TL, Kuppe C, Marsch E, de Bruijn J, Jin H, Gijbels MJ, Matic L, Mees BME, Reutelingsperger CPM, Hedin U, Biessen EAL, Carmeliet P, Baker AH, Kramann RK, Schurgers LJ, Saez-Rodriguez J, Sluimer JC.
PMID: 33913468
Cardiovasc Res. 2021 Apr 26; doi: 10.1093/cvr/cvab152. Epub 2021 Apr 26.

AIMS: Atherosclerotic plaque hypoxia is detrimental for macrophage function. Prolyl hydroxylases (PHDs) initiate cellular hypoxic responses, possibly influencing macrophage function in plaque hypoxia. Thus, we aimed to elucidate the role of myeloid PHDs in atherosclerosis.METHODS & RESULTS: Myeloid specific...

The RNA binding protein human antigen R is a gatekeeper of liver homeostasis.

Hepatology (Baltimore, Md.)

Subramanian P, Gargani S, Palladini A, Chatzimike M, Grzybek M, Peitzsch M, Papanastasiou AD, Pyrina I, Ntafis V, Gercken B, Lesche M, Petzold A, Sinha A, Nati M, Thangapandi VR, Kourtzelis I, Andreadou M, Witt A, Dahl A, Burkhardt R, Haase R, Domingues AMJ, Henry I, Zamboni N, Mirtschink P, Chung KJ, Hampe J, Coskun Ü, Kontoyiannis DL, Chavakis T.
PMID: 34519101
Hepatology. 2021 Sep 14; doi: 10.1002/hep.32153. Epub 2021 Sep 14.

BACKGROUND AND AIMS: NAFLD is initiated by steatosis and can progress through fibrosis and cirrhosis to HCC. The RNA binding protein human antigen R (HuR) controls RNAs at the posttranscriptional level; hepatocyte HuR has been implicated in the regulation...

Serum and urinary biomarkers for early detection of acute kidney injury following Hypnale spp. envenoming.

PLoS neglected tropical diseases

Wijewickrama ES, Mohamed F, Gawarammana IB, Endre ZH, Buckley NA, Isbister GK.
PMID: 34871314
PLoS Negl Trop Dis. 2021 Dec 06;15(12):e0010011. doi: 10.1371/journal.pntd.0010011. eCollection 2021 Dec.

BACKGROUND: Hump-nosed pit viper (HNV; Hypnale spp.) bites account for most venomous snakebites in Sri Lanka. Acute kidney injury (AKI) is the most serious systemic manifestation (1-10%) following HNV envenoming. We aimed to identify the value of functional and...

TRIM32 inhibits the proliferation and migration of pulmonary artery smooth muscle cells through the inactivation of PI3K/Akt pathway in pulmonary arterial hypertension.

Journal of bioenergetics and biomembranes

Hu Z, Song Q, Ma H, Guo Y, Zhang T, Xie H, Luo X.
PMID: 33694017
J Bioenerg Biomembr. 2021 Jun;53(3):309-320. doi: 10.1007/s10863-021-09880-w. Epub 2021 Mar 10.

Pulmonary arterial hypertension (PAH) is a progressive and fetal cardiovascular disease. Tripartite motif 32 (TRIM32) is a member of TRIM family that has been found to be involved in cardiovascular disease. However, the role of TRIM32 in PAH remains...

Relationship of Pain Catastrophizing With Urinary Biomarkers in Women With Bladder Pain Syndrome.

Female pelvic medicine & reconstructive surgery

Soriano A, Allen A, Malykhina AP, Andy U, Harvie H, Arya L.
PMID: 33787562
Female Pelvic Med Reconstr Surg. 2021 Dec 01;27(12):746-752. doi: 10.1097/SPV.0000000000001041.

OBJECTIVES: Brain-derived neurotrophic factor (BDNF) has been implicated in central neurological processes. We hypothesize that greater pain catastrophizing is associated with higher urinary BDNF levels in women with bladder pain syndrome.METHODS: A secondary analysis of a database of women...

Showing 1105 to 1115 of 1115 entries