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Showing 25 to 36 of 1368 entries
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Platelet-rich concentrate in serum free medium enhances osteogenic differentiation of bone marrow-derived human mesenchymal stromal cells.

PeerJ

Samuel S, Ahmad RE, Ramasamy TS, Karunanithi P, Naveen SV, Murali MR, Abbas AA, Kamarul T.
PMID: 27651984
PeerJ. 2016 Sep 07;4:e2347. doi: 10.7717/peerj.2347. eCollection 2016.

Previous studies have shown that platelet concentrates used in conjunction with appropriate growth media enhance osteogenic differentiation of human mesenchymal stromal cells (hMSCs). However, their potential in inducing osteogenesis of hMSCs when cultured in serum free medium has not...

Calcifying circulating cells: an uncharted area in the setting of vascular calcification in CKD patients.

Clinical kidney journal

Cianciolo G, Capelli I, Cappuccilli M, Schillaci R, Cozzolino M, La Manna G.
PMID: 26985381
Clin Kidney J. 2016 Apr;9(2):280-6. doi: 10.1093/ckj/sfv145. Epub 2016 Jan 18.

Vascular calcification, occurring during late-stage vascular and valvular disease, is highly associated with chronic kidney disease-mineral and bone disorders (CKD-MBD), representing a major risk factor for cardiovascular morbidity and mortality. The hallmark of vascular calcification, which involves both media...

Bergenin increases osteogenic differentiation and prevents methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblasts.

Cytotechnology

Suh KS, Chon S, Choi EM.
PMID: 28895006
Cytotechnology. 2018 Feb;70(1):215-224. doi: 10.1007/s10616-017-0135-y. Epub 2017 Sep 11.

Bergenin, an active component of plants in the genus Bergenia, has multiple biological activities, including anti-inflammatory and immunomodulatory properties. We investigated the effects of bergenin on MC3T3-E1 osteoblasts. Bergenin treatment significantly elevated collagen synthesis, alkaline phosphatase activity, osteocalcin synthesis,...

Canola and hydrogenated soybean oils accelerate ectopic bone formation induced by implantation of bone morphogenetic protein in mice.

Toxicology reports

Hashimoto Y, Mori M, Kobayashi S, Hanya A, Watanabe SI, Ohara N, Noguchi T, Kawai T, Okuyama H.
PMID: 28962307
Toxicol Rep. 2014 Nov 04;1:955-962. doi: 10.1016/j.toxrep.2014.10.021. eCollection 2014.

Canola oil (Can) and hydrogenated soybean oil (H2-Soy) are commonly used edible oils. However, in contrast to soybean oil (Soy), they shorten the survival of stroke-prone spontaneously hypertensive (SHRSP) rats. It has been proposed that the adverse effects of...

Effects of the donor age on proliferation, senescence and osteogenic capacity of human urine-derived stem cells.

Cytotechnology

Gao P, Han P, Jiang D, Yang S, Cui Q, Li Z.
PMID: 28409292
Cytotechnology. 2017 Oct;69(5):751-763. doi: 10.1007/s10616-017-0084-5. Epub 2017 Apr 13.

To study the effects of the donor age on the application potential of human urine-derived stem cells (hUSCs) in bone tissue engineering, by comparing proliferation, senescence and osteogenic differentiation of hUSCs originated from volunteers with different ages. The urine...

Medial tibial subchondral bone is the key target for extracorporeal shockwave therapy in early osteoarthritis of the knee.

American journal of translational research

Wang CJ, Cheng JH, Huang CY, Hsu SL, Lee FY, Yip HK.
PMID: 28469777
Am J Transl Res. 2017 Apr 15;9(4):1720-1731. eCollection 2017.

Extracorporeal shockwave therapy (ESWT) is a new non-invasive method to induce tissue regeneration and repair the damaged osteoarthritis (OA) of knee. Previous studies suggested subchondral bone as the key target for OA treatment. However, the relationship of the effect...

Blocking c-Met signaling enhances bone morphogenetic protein-2-induced osteoblast differentiation.

FEBS open bio

Shibasaki S, Kitano S, Karasaki M, Tsunemi S, Sano H, Iwasaki T.
PMID: 25941631
FEBS Open Bio. 2015 Apr 20;5:341-7. doi: 10.1016/j.fob.2015.04.008. eCollection 2015.

We previously demonstrated that blocking hepatocyte growth factor (HGF) receptor/c-Met signaling inhibited arthritis and articular bone destruction in mouse models of rheumatoid arthritis (RA). In the present study, we investigated the role of c-Met signaling in osteoblast differentiation using...

Pulsed electromagnetic fields promote in vitro osteoblastogenesis through a Wnt/β-catenin signaling-associated mechanism.

Bioelectromagnetics

Zhai M, Jing D, Tong S, Wu Y, Wang P, Zeng Z, Shen G, Wang X, Xu Q, Luo E.
PMID: 26891468
Bioelectromagnetics. 2016 Apr;37(3):152-162. doi: 10.1002/bem.21961. Epub 2016 Feb 18.

Substantial evidence indicates that pulsed electromagnetic fields (PEMF) could accelerate fracture healing and enhance bone mass, whereas the unclear mechanism by which PEMF stimulation promotes osteogenesis limits its extensive clinical application. In the present study, effects and potential molecular...

Effects of anti-sclerostin antibody and running on bone remodeling and strength.

Bone reports

Toumi H, Benaitreau D, Pallu S, Mazor M, Hambli R, Ominsky M, Lespessailles E.
PMID: 28377954
Bone Rep. 2015 Apr 11;2:52-58. doi: 10.1016/j.bonr.2015.03.002. eCollection 2015 Jun.

Sclerostin antibody (Scl-Ab) represents a promising therapeutic approach to treat patients with osteoporosis.PURPOSE: The aim of this study was to investigate the effects of Scl-Ab, running and a combination of both on bone formation.METHODS: Sixty female Wistar rats, aged...

IGF-1 Signaling is Essential for Differentiation of Mesenchymal Stem Cells for Peak Bone Mass.

Bone research

Crane JL, Zhao L, Frye JS, Xian L, Qiu T, Cao X.
PMID: 26273502
Bone Res. 2013 Jun 28;1(2):186-94. doi: 10.4248/BR201302007. eCollection 2013 Jun.

Survival of children with chronic medical illnesses is leading to an increase in secondary osteoporosis due to impaired peak bone mass (PBM). Insulin-like growth factor type 1 (IGF-1) levels correlate with the pattern of bone mass accrual and many...

Dual pathways to endochondral osteoblasts: a novel chondrocyte-derived osteoprogenitor cell identified in hypertrophic cartilage.

Biology open

Park J, Gebhardt M, Golovchenko S, Perez-Branguli F, Hattori T, Hartmann C, Zhou X, deCrombrugghe B, Stock M, Schneider H, von der Mark K.
PMID: 25882555
Biol Open. 2015 Apr 16;4(5):608-21. doi: 10.1242/bio.201411031.

According to the general understanding, the chondrocyte lineage terminates with the elimination of late hypertrophic cells by apoptosis in the growth plate. However, recent cell tracking studies have shown that murine hypertrophic chondrocytes can survive beyond "terminal" differentiation and...

Biological characteristics of muscle-derived satellite cells isolated from rats at different postnatal days.

Cytotechnology

Yu R, Haiqing W, Hefei W, Dong L, Xiao W, Yuzhen M, Dongjun L.
PMID: 25805267
Cytotechnology. 2015 May;67(3):397-408. doi: 10.1007/s10616-013-9670-3. Epub 2015 Feb 18.

This study investigated the in vitro growth characteristics and differential potential of muscle-derived satellite cells (MDSCs) derived from rats at different postnatal (P) stages, in order to expand the range of source material for tissue engineering. Rat MDSCs were...

Showing 25 to 36 of 1368 entries