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Comparing the Osteogenic Potential and Bone Regeneration Capacities of Dedifferentiated Fat Cells and Adipose-Derived Stem Cells In Vitro and In Vivo: Application of DFAT Cells Isolated by a Mesh Method.

International journal of molecular sciences

Takabatake K, Matsubara M, Yamachika E, Fujita Y, Arimura Y, Nakatsuji K, Nakano K, Nagatsuka H, Iida S.
PMID: 34830277
Int J Mol Sci. 2021 Nov 17;22(22). doi: 10.3390/ijms222212392.

BACKGROUND: We investigated and compared the osteogenic potential and bone regeneration capacities of dedifferentiated fat cells (DFAT cells) and adipose-derived stem cells (ASCs).METHOD: We isolated DFAT cells and ASCs from GFP mice. DFAT cells were established by a new...

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Takabatake K, Matsubara M, Yamachika E, et al. Comparing the Osteogenic Potential and Bone Regeneration Capacities of Dedifferentiated Fat Cells and Adipose-Derived Stem Cells In Vitro and In Vivo: Application of DFAT Cells Isolated by a Mesh Method. Int J Mol Sci. 2021;22(22)doi: 10.3390/ijms222212392.
Takabatake, K., Matsubara, M., Yamachika, E., Fujita, Y., Arimura, Y., Nakatsuji, K., Nakano, K., Nagatsuka, H., & Iida, S. (2021). Comparing the Osteogenic Potential and Bone Regeneration Capacities of Dedifferentiated Fat Cells and Adipose-Derived Stem Cells In Vitro and In Vivo: Application of DFAT Cells Isolated by a Mesh Method. International journal of molecular sciences, 22(22), . https://doi.org/10.3390/ijms222212392
Takabatake, Kiyofumi, et al. "Comparing the Osteogenic Potential and Bone Regeneration Capacities of Dedifferentiated Fat Cells and Adipose-Derived Stem Cells In Vitro and In Vivo: Application of DFAT Cells Isolated by a Mesh Method." International journal of molecular sciences vol. 22,22 (2021). doi: https://doi.org/10.3390/ijms222212392
Takabatake K, Matsubara M, Yamachika E, Fujita Y, Arimura Y, Nakatsuji K, Nakano K, Nagatsuka H, Iida S. Comparing the Osteogenic Potential and Bone Regeneration Capacities of Dedifferentiated Fat Cells and Adipose-Derived Stem Cells In Vitro and In Vivo: Application of DFAT Cells Isolated by a Mesh Method. Int J Mol Sci. 2021 Nov 17;22(22). doi: 10.3390/ijms222212392. PMID: 34830277; PMCID: PMC8620969.
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Adiponectin inhibits lipoplysaccharide-induced inflammation and promotes osteogenesis in hPDLCs.

Bioscience reports

Wu HH, Guo Y, Pu YF, Tang ZH.
PMID: 33616153
Biosci Rep. 2021 Mar 26;41(3). doi: 10.1042/BSR20192668.

Periodontal diseases are infections of the structures that surround and support the teeth; they are characterized by local inflammation and alveolar bone loss. Most treatments focus on only one aspect, inhibiting inflammation, or promoting osteoblasts. We set out to...

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Wu HH, Guo Y, Pu YF, et al. Adiponectin inhibits lipoplysaccharide-induced inflammation and promotes osteogenesis in hPDLCs. Biosci Rep. 2021;41(3)doi: 10.1042/BSR20192668.
Wu, H. H., Guo, Y., Pu, Y. F., & Tang, Z. H. (2021). Adiponectin inhibits lipoplysaccharide-induced inflammation and promotes osteogenesis in hPDLCs. Bioscience reports, 41(3), . https://doi.org/10.1042/BSR20192668
Wu, Huan-Huan, et al. "Adiponectin inhibits lipoplysaccharide-induced inflammation and promotes osteogenesis in hPDLCs." Bioscience reports vol. 41,3 (2021). doi: https://doi.org/10.1042/BSR20192668
Wu HH, Guo Y, Pu YF, Tang ZH. Adiponectin inhibits lipoplysaccharide-induced inflammation and promotes osteogenesis in hPDLCs. Biosci Rep. 2021 Mar 26;41(3). doi: 10.1042/BSR20192668. PMID: 33616153; PMCID: PMC7926180.
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Bone-Forming Peptide-4 Induces Osteogenic Differentiation and VEGF Expression on Multipotent Bone Marrow Stromal Cells.

Frontiers in bioengineering and biotechnology

Kim ME, Seon JK, Kang JY, Yoon TR, Lee JS, Kim HK.
PMID: 34692657
Front Bioeng Biotechnol. 2021 Oct 06;9:734483. doi: 10.3389/fbioe.2021.734483. eCollection 2021.

Bone morphogenetic proteins (BMPs) have been widely used as treatment for bone repair. However, clinical trials on fracture repair have challenged the effectiveness of BMPs and suggested that delivery of multipotent bone marrow stromal cells (BMSCs) might be beneficial....

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Kim ME, Seon JK, Kang JY, et al. Bone-Forming Peptide-4 Induces Osteogenic Differentiation and VEGF Expression on Multipotent Bone Marrow Stromal Cells. Front Bioeng Biotechnol. 2021;9:734483doi: 10.3389/fbioe.2021.734483.
Kim, M. E., Seon, J. K., Kang, J. Y., Yoon, T. R., Lee, J. S., & Kim, H. K. (2021). Bone-Forming Peptide-4 Induces Osteogenic Differentiation and VEGF Expression on Multipotent Bone Marrow Stromal Cells. Frontiers in bioengineering and biotechnology, 9734483. https://doi.org/10.3389/fbioe.2021.734483
Kim, Mi Eun, et al. "Bone-Forming Peptide-4 Induces Osteogenic Differentiation and VEGF Expression on Multipotent Bone Marrow Stromal Cells." Frontiers in bioengineering and biotechnology vol. 9 (2021): 734483. doi: https://doi.org/10.3389/fbioe.2021.734483
Kim ME, Seon JK, Kang JY, Yoon TR, Lee JS, Kim HK. Bone-Forming Peptide-4 Induces Osteogenic Differentiation and VEGF Expression on Multipotent Bone Marrow Stromal Cells. Front Bioeng Biotechnol. 2021 Oct 06;9:734483. doi: 10.3389/fbioe.2021.734483. eCollection 2021. PMID: 34692657; PMCID: PMC8526923.
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Lycopene nanoparticles promotes osteoblastogenesis and inhibits adipogenesis of rat bone marrow mesenchymal stem cells.

European review for medical and pharmacological sciences

Ardawi MSM, Badawoud MH, Hassan SM, Ardawi AMS, Rouzi AA, Qari MH, Mousa SA.
PMID: 34859851
Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):6894-6907. doi: 10.26355/eurrev_202111_27238.

OBJECTIVE: Lycopene is a carotenoid and antioxidant with potent singlet oxygen quenching ability that reduces oxidative stress and promotes bone health. However, the cellular mechanisms by which lycopene influences bone metabolism are not known.MATERIALS AND METHODS: The present study...

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Ardawi MSM, Badawoud MH, Hassan SM, et al. Lycopene nanoparticles promotes osteoblastogenesis and inhibits adipogenesis of rat bone marrow mesenchymal stem cells. Eur Rev Med Pharmacol Sci. 2021;25(22):6894-6907doi: 10.26355/eurrev_202111_27238.
Ardawi, M. S. M., Badawoud, M. H., Hassan, S. M., Ardawi, A. M. S., Rouzi, A. A., Qari, M. H., & Mousa, S. A. (2021). Lycopene nanoparticles promotes osteoblastogenesis and inhibits adipogenesis of rat bone marrow mesenchymal stem cells. European review for medical and pharmacological sciences, 25(22), 6894-6907. https://doi.org/10.26355/eurrev_202111_27238
Ardawi, M S M, et al. "Lycopene nanoparticles promotes osteoblastogenesis and inhibits adipogenesis of rat bone marrow mesenchymal stem cells." European review for medical and pharmacological sciences vol. 25,22 (2021): 6894-6907. doi: https://doi.org/10.26355/eurrev_202111_27238
Ardawi MSM, Badawoud MH, Hassan SM, Ardawi AMS, Rouzi AA, Qari MH, Mousa SA. Lycopene nanoparticles promotes osteoblastogenesis and inhibits adipogenesis of rat bone marrow mesenchymal stem cells. Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):6894-6907. doi: 10.26355/eurrev_202111_27238. PMID: 34859851.
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Determination of osteocalcin in meat and bone meal of bovine and porcine origin using matrix-assisted laser desorption ionization/time-of-flight mass spectrometry and high-resolution hybrid mass spectrometry.

Analytica chimica acta

Balizs G, Weise C, Rozycki C, Opialla T, Sawada S, Zagon J, Lampen A.
PMID: 21504815
Anal Chim Acta. 2011 May 05;693(1):89-99. doi: 10.1016/j.aca.2011.03.027. Epub 2011 Mar 16.

A method has been developed for determining the origin of meat and bone meal (MBM) by detecting species-specific osteocalcin (OC) using matrix-assisted laser desorption ionization/time-of-flight (MALDI/TOF) and high-resolution hybrid mass spectrometry (HR-Q/TOF MS). The analysis is based on the...

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Balizs G, Weise C, Rozycki C, et al. Determination of osteocalcin in meat and bone meal of bovine and porcine origin using matrix-assisted laser desorption ionization/time-of-flight mass spectrometry and high-resolution hybrid mass spectrometry. Anal Chim Acta. 2011;693(1):89-99doi: 10.1016/j.aca.2011.03.027.
Balizs, G., Weise, C., Rozycki, C., Opialla, T., Sawada, S., Zagon, J., & Lampen, A. (2011). Determination of osteocalcin in meat and bone meal of bovine and porcine origin using matrix-assisted laser desorption ionization/time-of-flight mass spectrometry and high-resolution hybrid mass spectrometry. Analytica chimica acta, 693(1), 89-99. https://doi.org/10.1016/j.aca.2011.03.027
Balizs, Gabor, et al. "Determination of osteocalcin in meat and bone meal of bovine and porcine origin using matrix-assisted laser desorption ionization/time-of-flight mass spectrometry and high-resolution hybrid mass spectrometry." Analytica chimica acta vol. 693,1 (2011): 89-99. doi: https://doi.org/10.1016/j.aca.2011.03.027
Balizs G, Weise C, Rozycki C, Opialla T, Sawada S, Zagon J, Lampen A. Determination of osteocalcin in meat and bone meal of bovine and porcine origin using matrix-assisted laser desorption ionization/time-of-flight mass spectrometry and high-resolution hybrid mass spectrometry. Anal Chim Acta. 2011 May 05;693(1):89-99. doi: 10.1016/j.aca.2011.03.027. Epub 2011 Mar 16. PMID: 21504815.
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MicroRNA miR-874-3p inhibits osteoporosis by targeting leptin (LEP).

Bioengineered

Mei L, Li M, Zhang T.
PMID: 34818977
Bioengineered. 2021 Nov 24; doi: 10.1080/21655979.2021.2009618. Epub 2021 Nov 24.

MicroRNAs (miRNAs) regulate osteogenic differentiation and influence osteoporosis (OP). The aim of this study was to determine the potential role of miR-874-3p in OP. The expression levels of miR-874-3p and leptin (LEP) in the femoral neck trabeculae of 35...

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Mei L, Li M, Zhang T. MicroRNA miR-874-3p inhibits osteoporosis by targeting leptin (LEP). Bioengineered. 2021;doi: 10.1080/21655979.2021.2009618.
Mei, L., Li, M., & Zhang, T. (2021). MicroRNA miR-874-3p inhibits osteoporosis by targeting leptin (LEP). Bioengineered, . https://doi.org/10.1080/21655979.2021.2009618
Mei, Ling, et al. "MicroRNA miR-874-3p inhibits osteoporosis by targeting leptin (LEP)." Bioengineered vol. (2021). doi: https://doi.org/10.1080/21655979.2021.2009618
Mei L, Li M, Zhang T. MicroRNA miR-874-3p inhibits osteoporosis by targeting leptin (LEP). Bioengineered. 2021 Nov 24; doi: 10.1080/21655979.2021.2009618. Epub 2021 Nov 24. PMID: 34818977.
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Multifunctional Tannic Acid-Alendronate Nanocomplexes with Antioxidant, Anti-Inflammatory, and Osteogenic Potency.

Nanomaterials (Basel, Switzerland)

Choi S, Jo HS, Song H, Kim HJ, Oh JK, Cho JW, Park K, Kim SE.
PMID: 34361198
Nanomaterials (Basel). 2021 Jul 13;11(7). doi: 10.3390/nano11071812.

In the current study, we fabricated tannic acid-alendronate (TA-ALN) nanocomplexes (NPXs) via self-assembly. These TA-ALNs were characterized by dynamic light scattering, zeta potential, transmission electron microscopy, and FT-IR spectroscopy. The TA-ALNs were evaluated for antioxidant, anti-inflammatory, and osteogenesis-accelerating abilities...

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Choi S, Jo HS, Song H, et al. Multifunctional Tannic Acid-Alendronate Nanocomplexes with Antioxidant, Anti-Inflammatory, and Osteogenic Potency. Nanomaterials (Basel). 2021;11(7)doi: 10.3390/nano11071812.
Choi, S., Jo, H. S., Song, H., Kim, H. J., Oh, J. K., Cho, J. W., Park, K., & Kim, S. E. (2021). Multifunctional Tannic Acid-Alendronate Nanocomplexes with Antioxidant, Anti-Inflammatory, and Osteogenic Potency. Nanomaterials (Basel, Switzerland), 11(7), . https://doi.org/10.3390/nano11071812
Choi, Somang, et al. "Multifunctional Tannic Acid-Alendronate Nanocomplexes with Antioxidant, Anti-Inflammatory, and Osteogenic Potency." Nanomaterials (Basel, Switzerland) vol. 11,7 (2021). doi: https://doi.org/10.3390/nano11071812
Choi S, Jo HS, Song H, Kim HJ, Oh JK, Cho JW, Park K, Kim SE. Multifunctional Tannic Acid-Alendronate Nanocomplexes with Antioxidant, Anti-Inflammatory, and Osteogenic Potency. Nanomaterials (Basel). 2021 Jul 13;11(7). doi: 10.3390/nano11071812. PMID: 34361198; PMCID: PMC8308329.
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Hirudin promotes proliferation and osteogenic differentiation of HBMSCs via activation of cyclic guanosine monophosphate (cGMP)/protein kinase-G (PKG) signaling pathway.

Bioengineered

Cao S, Li X, Feng T, Li Y, Ding H, Xie L, Yang Q.
PMID: 34898364
Bioengineered. 2021 Dec 13; doi: 10.1080/21655979.2021.2008697. Epub 2021 Dec 13.

Osteoporosis is a public health problem resulting in higher susceptibility to bone fracture. Hirudin is known as a direct thrombin inhibitor, which is isolated from the salivary gland of the medicinal leech. This present study aimed to evaluate the...

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Cao S, Li X, Feng T, et al. Hirudin promotes proliferation and osteogenic differentiation of HBMSCs via activation of cyclic guanosine monophosphate (cGMP)/protein kinase-G (PKG) signaling pathway. Bioengineered. 2021;doi: 10.1080/21655979.2021.2008697.
Cao, S., Li, X., Feng, T., Li, Y., Ding, H., Xie, L., & Yang, Q. (2021). Hirudin promotes proliferation and osteogenic differentiation of HBMSCs via activation of cyclic guanosine monophosphate (cGMP)/protein kinase-G (PKG) signaling pathway. Bioengineered, . https://doi.org/10.1080/21655979.2021.2008697
Cao, Shun, et al. "Hirudin promotes proliferation and osteogenic differentiation of HBMSCs via activation of cyclic guanosine monophosphate (cGMP)/protein kinase-G (PKG) signaling pathway." Bioengineered vol. (2021). doi: https://doi.org/10.1080/21655979.2021.2008697
Cao S, Li X, Feng T, Li Y, Ding H, Xie L, Yang Q. Hirudin promotes proliferation and osteogenic differentiation of HBMSCs via activation of cyclic guanosine monophosphate (cGMP)/protein kinase-G (PKG) signaling pathway. Bioengineered. 2021 Dec 13; doi: 10.1080/21655979.2021.2008697. Epub 2021 Dec 13. PMID: 34898364.
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Evaluation of Gingival Crevicular Fluid and Serum Tartrate-resistant Acid Phosphatase Levels in Subjects with Clinically Healthy Periodontium and Chronic Periodontitis - A Clinico-biochemical Study.

Journal of pharmacy & bioallied sciences

Baddam H, Vivekanandan G, Kondreddy K, Peddi S, Chitnis PP, Singh YP, Tiwar RVC.
PMID: 35017970
J Pharm Bioallied Sci. 2021 Nov;13:S1275-S1279. doi: 10.4103/jpbs.jpbs_90_21. Epub 2021 Nov 10.

BACKGROUND: Periodontitis is a chronic inflammatory disease with conglomerate etiology making it difficult to diagnose at the early stages. Potential biomarkers in gingival crevicular fluid (GCF) would determine the presence of the current disease activity, predict sites vulnerable for...

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Baddam H, Vivekanandan G, Kondreddy K, et al. Evaluation of Gingival Crevicular Fluid and Serum Tartrate-resistant Acid Phosphatase Levels in Subjects with Clinically Healthy Periodontium and Chronic Periodontitis - A Clinico-biochemical Study. J Pharm Bioallied Sci. 2021;13:S1275-S1279doi: 10.4103/jpbs.jpbs_90_21.
Baddam, H., Vivekanandan, G., Kondreddy, K., Peddi, S., Chitnis, P. P., Singh, Y. P., & Tiwar, R. V. C. (2021). Evaluation of Gingival Crevicular Fluid and Serum Tartrate-resistant Acid Phosphatase Levels in Subjects with Clinically Healthy Periodontium and Chronic Periodontitis - A Clinico-biochemical Study. Journal of pharmacy & bioallied sciences, 13S1275-S1279. https://doi.org/10.4103/jpbs.jpbs_90_21
Baddam, Harshitha, et al. "Evaluation of Gingival Crevicular Fluid and Serum Tartrate-resistant Acid Phosphatase Levels in Subjects with Clinically Healthy Periodontium and Chronic Periodontitis - A Clinico-biochemical Study." Journal of pharmacy & bioallied sciences vol. 13 (2021): S1275-S1279. doi: https://doi.org/10.4103/jpbs.jpbs_90_21
Baddam H, Vivekanandan G, Kondreddy K, Peddi S, Chitnis PP, Singh YP, Tiwar RVC. Evaluation of Gingival Crevicular Fluid and Serum Tartrate-resistant Acid Phosphatase Levels in Subjects with Clinically Healthy Periodontium and Chronic Periodontitis - A Clinico-biochemical Study. J Pharm Bioallied Sci. 2021 Nov;13:S1275-S1279. doi: 10.4103/jpbs.jpbs_90_21. Epub 2021 Nov 10. PMID: 35017970; PMCID: PMC8686990.
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Combination of 3D Printing and ALD for Dentin Fabrication from Dental Pulp Stem Cell Culture.

ACS applied bio materials

Feng KC, Li J, Wang L, Chuang YC, Liu H, Pinkas-Sarafova A, Chang CC, Nam CY, Simon M, Rafailovich M.
PMID: 35006688
ACS Appl Bio Mater. 2021 Oct 18;4(10):7422-7430. doi: 10.1021/acsabm.1c00577. Epub 2021 Sep 29.

A combination of fused deposition modeling printing with atomic layer deposition (ALD) of titania was designed to achieve templated biomineralization and terminal odontogenic differentiation of dental pulp stem cells on three-dimensional (3D) printed polylactic acid (PLA) scaffolds. In the...

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Feng KC, Li J, Wang L, et al. Combination of 3D Printing and ALD for Dentin Fabrication from Dental Pulp Stem Cell Culture. ACS Appl Bio Mater. 2021;4(10):7422-7430doi: 10.1021/acsabm.1c00577.
Feng, K. C., Li, J., Wang, L., Chuang, Y. C., Liu, H., Pinkas-Sarafova, A., Chang, C. C., Nam, C. Y., Simon, M., & Rafailovich, M. (2021). Combination of 3D Printing and ALD for Dentin Fabrication from Dental Pulp Stem Cell Culture. ACS applied bio materials, 4(10), 7422-7430. https://doi.org/10.1021/acsabm.1c00577
Feng, Kuan-Che, et al. "Combination of 3D Printing and ALD for Dentin Fabrication from Dental Pulp Stem Cell Culture." ACS applied bio materials vol. 4,10 (2021): 7422-7430. doi: https://doi.org/10.1021/acsabm.1c00577
Feng KC, Li J, Wang L, Chuang YC, Liu H, Pinkas-Sarafova A, Chang CC, Nam CY, Simon M, Rafailovich M. Combination of 3D Printing and ALD for Dentin Fabrication from Dental Pulp Stem Cell Culture. ACS Appl Bio Mater. 2021 Oct 18;4(10):7422-7430. doi: 10.1021/acsabm.1c00577. Epub 2021 Sep 29. PMID: 35006688.
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Evaluation of the efficacy of salmon calcitonin nasal spray on bone healing following open reduction and internal fixation of mandibular fractures - A randomized controlled trial.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

Roy A, Thulasiraman S, Panneerselvam E, Thulasi Doss G, Selvaraj MN, Ganesh SK, Raja KVB, Kangusamy B.
PMID: 34593298
J Craniomaxillofac Surg. 2021 Dec;49(12):1151-1157. doi: 10.1016/j.jcms.2021.08.002. Epub 2021 Aug 30.

The objective of this study was to assess the efficacy of calcitonin spray on bone healing following open reduction internal fixation (ORIF) of mandibular fractures. Fourteen patients were subdivided into a study group and a control group. A standardized...

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Roy A, Thulasiraman S, Panneerselvam E, et al. Evaluation of the efficacy of salmon calcitonin nasal spray on bone healing following open reduction and internal fixation of mandibular fractures - A randomized controlled trial. J Craniomaxillofac Surg. 2021;49(12):1151-1157doi: 10.1016/j.jcms.2021.08.002.
Roy, A., Thulasiraman, S., Panneerselvam, E., Thulasi Doss, G., Selvaraj, M. N., Ganesh, S. K., Raja, K. V. B., & Kangusamy, B. (2021). Evaluation of the efficacy of salmon calcitonin nasal spray on bone healing following open reduction and internal fixation of mandibular fractures - A randomized controlled trial. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 49(12), 1151-1157. https://doi.org/10.1016/j.jcms.2021.08.002
Roy, Aritra, et al. "Evaluation of the efficacy of salmon calcitonin nasal spray on bone healing following open reduction and internal fixation of mandibular fractures - A randomized controlled trial." Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery vol. 49,12 (2021): 1151-1157. doi: https://doi.org/10.1016/j.jcms.2021.08.002
Roy A, Thulasiraman S, Panneerselvam E, Thulasi Doss G, Selvaraj MN, Ganesh SK, Raja KVB, Kangusamy B. Evaluation of the efficacy of salmon calcitonin nasal spray on bone healing following open reduction and internal fixation of mandibular fractures - A randomized controlled trial. J Craniomaxillofac Surg. 2021 Dec;49(12):1151-1157. doi: 10.1016/j.jcms.2021.08.002. Epub 2021 Aug 30. PMID: 34593298.
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Shell water-soluble matrix protein from oyster shells promoted proliferation, differentiation and mineralization of osteoblasts in vitro and vivo.

International journal of biological macromolecules

Feng X, Jiang S, Zhang F, Wang R, Zhao Y, Zeng M.
PMID: 34998879
Int J Biol Macromol. 2022 Jan 05;201:288-297. doi: 10.1016/j.ijbiomac.2021.12.168. Epub 2022 Jan 05.

Matrix protein is secreted by the membrane of bivalve shellfish to and used to regulate shell biomineralization. In this study, we extracted water-soluble matrix protein (WSMP) from oyster shells to investigate its effects on osteogenic differentiation and mineralization of...

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Feng X, Jiang S, Zhang F, et al. Shell water-soluble matrix protein from oyster shells promoted proliferation, differentiation and mineralization of osteoblasts in vitro and vivo. Int J Biol Macromol. 2022;201:288-297doi: 10.1016/j.ijbiomac.2021.12.168.
Feng, X., Jiang, S., Zhang, F., Wang, R., Zhao, Y., & Zeng, M. (2022). Shell water-soluble matrix protein from oyster shells promoted proliferation, differentiation and mineralization of osteoblasts in vitro and vivo. International journal of biological macromolecules, 201288-297. https://doi.org/10.1016/j.ijbiomac.2021.12.168
Feng, Xue, et al. "Shell water-soluble matrix protein from oyster shells promoted proliferation, differentiation and mineralization of osteoblasts in vitro and vivo." International journal of biological macromolecules vol. 201 (2022): 288-297. doi: https://doi.org/10.1016/j.ijbiomac.2021.12.168
Feng X, Jiang S, Zhang F, Wang R, Zhao Y, Zeng M. Shell water-soluble matrix protein from oyster shells promoted proliferation, differentiation and mineralization of osteoblasts in vitro and vivo. Int J Biol Macromol. 2022 Jan 05;201:288-297. doi: 10.1016/j.ijbiomac.2021.12.168. Epub 2022 Jan 05. PMID: 34998879.
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