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MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis.

Frontiers in cell and developmental biology

Liu L, Yu T, Jin Y, Mai W, Zhou J, Zhao C.
PMID: 33732698
Front Cell Dev Biol. 2021 Mar 01;9:629893. doi: 10.3389/fcell.2021.629893. eCollection 2021.

The relevance of microRNA-15a (miR-15a) to autoimmunity has been reported. Herein, we intended to probe the potential roles of miR-15a shuttled by adipose-derived mesenchymal stem cells (adMSCs)-derived extracellular vesicles (Evs) in colorectal cancer (CRC). Initially, CRC cells were treated...

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Liu L, Yu T, Jin Y, et al. MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis. Front Cell Dev Biol. 2021;9:629893doi: 10.3389/fcell.2021.629893.
Liu, L., Yu, T., Jin, Y., Mai, W., Zhou, J., & Zhao, C. (2021). MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis. Frontiers in cell and developmental biology, 9629893. https://doi.org/10.3389/fcell.2021.629893
Liu, Lei, et al. "MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis." Frontiers in cell and developmental biology vol. 9 (2021): 629893. doi: https://doi.org/10.3389/fcell.2021.629893
Liu L, Yu T, Jin Y, Mai W, Zhou J, Zhao C. MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis. Front Cell Dev Biol. 2021 Mar 01;9:629893. doi: 10.3389/fcell.2021.629893. eCollection 2021. PMID: 33732698; PMCID: PMC7959841.
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Anterior cruciate ligament (ACL) repair using cortical or anchor fixation with suture tape augmentation vs ACL reconstruction: A comparative biomechanical analysis.

The Knee

Muench LN, Berthold DP, Archambault S, Slater M, Mehl J, Obopilwe E, Cote MP, Arciero RA, Chahla J, Lee Pace J.
PMID: 34875498
Knee. 2021 Dec 04;34:76-88. doi: 10.1016/j.knee.2021.09.003. Epub 2021 Dec 04.

BACKGROUND: The purpose was to compare knee kinematics in a cadaveric model of anterior cruciate ligament (ACL) repair using an adjustable-loop femoral cortical suspensory (AL-CSF) or independent bundle suture anchor fixation (IB-SAF) with suture tape augmentation to a bone-patellar...

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Muench LN, Berthold DP, Archambault S, et al. Anterior cruciate ligament (ACL) repair using cortical or anchor fixation with suture tape augmentation vs ACL reconstruction: A comparative biomechanical analysis. Knee. 2021;34:76-88doi: 10.1016/j.knee.2021.09.003.
Muench, L. N., Berthold, D. P., Archambault, S., Slater, M., Mehl, J., Obopilwe, E., Cote, M. P., Arciero, R. A., Chahla, J., & Lee Pace, J. (2021). Anterior cruciate ligament (ACL) repair using cortical or anchor fixation with suture tape augmentation vs ACL reconstruction: A comparative biomechanical analysis. The Knee, 3476-88. https://doi.org/10.1016/j.knee.2021.09.003
Muench, Lukas N, et al. "Anterior cruciate ligament (ACL) repair using cortical or anchor fixation with suture tape augmentation vs ACL reconstruction: A comparative biomechanical analysis." The Knee vol. 34 (2021): 76-88. doi: https://doi.org/10.1016/j.knee.2021.09.003
Muench LN, Berthold DP, Archambault S, Slater M, Mehl J, Obopilwe E, Cote MP, Arciero RA, Chahla J, Lee Pace J. Anterior cruciate ligament (ACL) repair using cortical or anchor fixation with suture tape augmentation vs ACL reconstruction: A comparative biomechanical analysis. Knee. 2021 Dec 04;34:76-88. doi: 10.1016/j.knee.2021.09.003. Epub 2021 Dec 04. PMID: 34875498.
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Chondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification.

Bone research

Yu T, Zhang J, Zhu W, Wang X, Bai Y, Feng B, Zhuang Q, Han C, Wang S, Hu Q, An S, Wan M, Dong S, Xu J, Weng X, Cao X.
PMID: 33731675
Bone Res. 2021 Mar 17;9(1):19. doi: 10.1038/s41413-021-00140-6.

Ankylosing spondylitis (AS) is chronic inflammatory arthritis with a progressive fusion of axial joints. Anti-inflammatory treatments such as anti-TNF-α antibody therapy suppress inflammation but do not effectively halt the progression of spine fusion in AS patients. Here we report...

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Yu T, Zhang J, Zhu W, et al. Chondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification. Bone Res. 2021;9(1):19doi: 10.1038/s41413-021-00140-6.
Yu, T., Zhang, J., Zhu, W., Wang, X., Bai, Y., Feng, B., Zhuang, Q., Han, C., Wang, S., Hu, Q., An, S., Wan, M., Dong, S., Xu, J., Weng, X., & Cao, X. (2021). Chondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification. Bone research, 9(1), 19. https://doi.org/10.1038/s41413-021-00140-6
Yu, Tao, et al. "Chondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification." Bone research vol. 9,1 (2021): 19. doi: https://doi.org/10.1038/s41413-021-00140-6
Yu T, Zhang J, Zhu W, Wang X, Bai Y, Feng B, Zhuang Q, Han C, Wang S, Hu Q, An S, Wan M, Dong S, Xu J, Weng X, Cao X. Chondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification. Bone Res. 2021 Mar 17;9(1):19. doi: 10.1038/s41413-021-00140-6. PMID: 33731675; PMCID: PMC7969928.
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Multiple deep tissue cultures in primary total hip arthroplasty: prognostic value for periprosthetic infection.

Hip international : the journal of clinical and experimental research on hip pathology and therapy

Ferro FP, Bessa FS, Miyahara H, Ejnisman L, Vicente JR, Croci AT.
PMID: 32538159
Hip Int. 2022 Jan;32(1):45-50. doi: 10.1177/1120700020932110. Epub 2020 Jun 14.

BACKGROUND: The risk of infection after total hip replacement (THR) is significant, with negative impact on quality of life and high costs. Bacteria can contaminate the surgical site despite aseptic techniques; however, there is debate regarding the benefit of...

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Ferro FP, Bessa FS, Miyahara H, et al. Multiple deep tissue cultures in primary total hip arthroplasty: prognostic value for periprosthetic infection. Hip Int. 2020;32(1):45-50doi: 10.1177/1120700020932110.
Ferro, F. P., Bessa, F. S., Miyahara, H., Ejnisman, L., Vicente, J. R., & Croci, A. T. (2022). Multiple deep tissue cultures in primary total hip arthroplasty: prognostic value for periprosthetic infection. Hip international : the journal of clinical and experimental research on hip pathology and therapy, 32(1), 45-50. https://doi.org/10.1177/1120700020932110
Ferro, Fernando P, et al. "Multiple deep tissue cultures in primary total hip arthroplasty: prognostic value for periprosthetic infection." Hip international : the journal of clinical and experimental research on hip pathology and therapy vol. 32,1 (2022): 45-50. doi: https://doi.org/10.1177/1120700020932110
Ferro FP, Bessa FS, Miyahara H, Ejnisman L, Vicente JR, Croci AT. Multiple deep tissue cultures in primary total hip arthroplasty: prognostic value for periprosthetic infection. Hip Int. 2022 Jan;32(1):45-50. doi: 10.1177/1120700020932110. Epub 2020 Jun 14. PMID: 32538159.
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NIR-II Ratiometric Lanthanide-Dye Hybrid Nanoprobes Doped Bioscaffolds for In Situ Bone Repair Monitoring.

Nano letters

Pei P, Hu H, Chen Y, Wang S, Chen J, Ming J, Yang Y, Sun C, Zhao S, Zhang F.
PMID: 35005958
Nano Lett. 2022 Jan 10; doi: 10.1021/acs.nanolett.1c04356. Epub 2022 Jan 10.

In situ monitoring of tissue regeneration progression is of primary importance to basic medical research and clinical transformation. Despite significant progress in the field of tissue engineering and regenerative medicine, few technologies have been established to in situ inspect...

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Pei P, Hu H, Chen Y, et al. NIR-II Ratiometric Lanthanide-Dye Hybrid Nanoprobes Doped Bioscaffolds for In Situ Bone Repair Monitoring. Nano Lett. 2022;doi: 10.1021/acs.nanolett.1c04356.
Pei, P., Hu, H., Chen, Y., Wang, S., Chen, J., Ming, J., Yang, Y., Sun, C., Zhao, S., & Zhang, F. (2022). NIR-II Ratiometric Lanthanide-Dye Hybrid Nanoprobes Doped Bioscaffolds for In Situ Bone Repair Monitoring. Nano letters, . https://doi.org/10.1021/acs.nanolett.1c04356
Pei, Peng, et al. "NIR-II Ratiometric Lanthanide-Dye Hybrid Nanoprobes Doped Bioscaffolds for In Situ Bone Repair Monitoring." Nano letters vol. (2022). doi: https://doi.org/10.1021/acs.nanolett.1c04356
Pei P, Hu H, Chen Y, Wang S, Chen J, Ming J, Yang Y, Sun C, Zhao S, Zhang F. NIR-II Ratiometric Lanthanide-Dye Hybrid Nanoprobes Doped Bioscaffolds for In Situ Bone Repair Monitoring. Nano Lett. 2022 Jan 10; doi: 10.1021/acs.nanolett.1c04356. Epub 2022 Jan 10. PMID: 35005958.
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Developments in pediatrics in 2020: choices in allergy, autoinflammatory disorders, critical care, endocrinology, genetics, infectious diseases, microbiota, neonatology, neurology, nutrition, ortopedics, respiratory tract illnesses and rheumatology.

Italian journal of pediatrics

Caffarelli C, Santamaria F, Procaccianti M, Piro E, Delle Cave V, Borrelli M, Santoro A, Grassi F, Bernasconi S, Corsello G.
PMID: 34876198
Ital J Pediatr. 2021 Dec 07;47(1):232. doi: 10.1186/s13052-021-01184-4.

In this article, we describe the advances in the field of pediatrics that have been published in the Italian Journal of Pediatrics in 2020. We report progresses in understanding allergy, autoinflammatory disorders, critical care, endocrinology, genetics, infectious diseases, microbiota,...

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Caffarelli C, Santamaria F, Procaccianti M, et al. Developments in pediatrics in 2020: choices in allergy, autoinflammatory disorders, critical care, endocrinology, genetics, infectious diseases, microbiota, neonatology, neurology, nutrition, ortopedics, respiratory tract illnesses and rheumatology. Ital J Pediatr. 2021;47(1):232doi: 10.1186/s13052-021-01184-4.
Caffarelli, C., Santamaria, F., Procaccianti, M., Piro, E., Delle Cave, V., Borrelli, M., Santoro, A., Grassi, F., Bernasconi, S., & Corsello, G. (2021). Developments in pediatrics in 2020: choices in allergy, autoinflammatory disorders, critical care, endocrinology, genetics, infectious diseases, microbiota, neonatology, neurology, nutrition, ortopedics, respiratory tract illnesses and rheumatology. Italian journal of pediatrics, 47(1), 232. https://doi.org/10.1186/s13052-021-01184-4
Caffarelli, Carlo, et al. "Developments in pediatrics in 2020: choices in allergy, autoinflammatory disorders, critical care, endocrinology, genetics, infectious diseases, microbiota, neonatology, neurology, nutrition, ortopedics, respiratory tract illnesses and rheumatology." Italian journal of pediatrics vol. 47,1 (2021): 232. doi: https://doi.org/10.1186/s13052-021-01184-4
Caffarelli C, Santamaria F, Procaccianti M, Piro E, Delle Cave V, Borrelli M, Santoro A, Grassi F, Bernasconi S, Corsello G. Developments in pediatrics in 2020: choices in allergy, autoinflammatory disorders, critical care, endocrinology, genetics, infectious diseases, microbiota, neonatology, neurology, nutrition, ortopedics, respiratory tract illnesses and rheumatology. Ital J Pediatr. 2021 Dec 07;47(1):232. doi: 10.1186/s13052-021-01184-4. PMID: 34876198; PMCID: PMC8650733.
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Association Between the Physician Quality Score in the Merit-Based Incentive Payment System and Hospital Performance in Hospital Compare in the First Year of the Program.

JAMA network open

Glance LG, Thirukumaran CP, Feng C, Lustik SJ, Dick AW.
PMID: 34342653
JAMA Netw Open. 2021 Aug 02;4(8):e2118449. doi: 10.1001/jamanetworkopen.2021.18449.

IMPORTANCE: The scientific validity of the Merit-Based Incentive Payment System (MIPS) quality score as a measure of hospital-level patient outcomes is unknown.OBJECTIVE: To examine whether better physician performance on the MIPS quality score is associated with better hospital outcomes.DESIGN,...

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Glance LG, Thirukumaran CP, Feng C, et al. Association Between the Physician Quality Score in the Merit-Based Incentive Payment System and Hospital Performance in Hospital Compare in the First Year of the Program. JAMA Netw Open. 2021;4(8):e2118449doi: 10.1001/jamanetworkopen.2021.18449.
Glance, L. G., Thirukumaran, C. P., Feng, C., Lustik, S. J., & Dick, A. W. (2021). Association Between the Physician Quality Score in the Merit-Based Incentive Payment System and Hospital Performance in Hospital Compare in the First Year of the Program. JAMA network open, 4(8), e2118449. https://doi.org/10.1001/jamanetworkopen.2021.18449
Glance, Laurent G, et al. "Association Between the Physician Quality Score in the Merit-Based Incentive Payment System and Hospital Performance in Hospital Compare in the First Year of the Program." JAMA network open vol. 4,8 (2021): e2118449. doi: https://doi.org/10.1001/jamanetworkopen.2021.18449
Glance LG, Thirukumaran CP, Feng C, Lustik SJ, Dick AW. Association Between the Physician Quality Score in the Merit-Based Incentive Payment System and Hospital Performance in Hospital Compare in the First Year of the Program. JAMA Netw Open. 2021 Aug 02;4(8):e2118449. doi: 10.1001/jamanetworkopen.2021.18449. PMID: 34342653; PMCID: PMC8335582.
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Modified poly(methyl methacrylate) bone cement in the treatment of Kümmell disease.

Regenerative biomaterials

Zhu J, Yang S, Yang Y, Yao T, Liu G, Fan S, Zhao H, Cui F, Wang X, Jiang G, Fang X.
PMID: 33732497
Regen Biomater. 2021 Jan 09;8(1):rbaa051. doi: 10.1093/rb/rbaa051. eCollection 2021 Feb 01.

Kümmell disease (KD) causes serious vertebral body collapse in patients. However, only a few case reports have been conducted and the number of patients with KD investigated was limited. Additionally, the frequently used poly(methyl methacrylate) (PMMA) bone cement for...

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Zhu J, Yang S, Yang Y, et al. Modified poly(methyl methacrylate) bone cement in the treatment of Kümmell disease. Regen Biomater. 2021;8(1):rbaa051doi: 10.1093/rb/rbaa051.
Zhu, J., Yang, S., Yang, Y., Yao, T., Liu, G., Fan, S., Zhao, H., Cui, F., Wang, X., Jiang, G., & Fang, X. (2021). Modified poly(methyl methacrylate) bone cement in the treatment of Kümmell disease. Regenerative biomaterials, 8(1), rbaa051. https://doi.org/10.1093/rb/rbaa051
Zhu, Jinjin, et al. "Modified poly(methyl methacrylate) bone cement in the treatment of Kümmell disease." Regenerative biomaterials vol. 8,1 (2021): rbaa051. doi: https://doi.org/10.1093/rb/rbaa051
Zhu J, Yang S, Yang Y, Yao T, Liu G, Fan S, Zhao H, Cui F, Wang X, Jiang G, Fang X. Modified poly(methyl methacrylate) bone cement in the treatment of Kümmell disease. Regen Biomater. 2021 Jan 09;8(1):rbaa051. doi: 10.1093/rb/rbaa051. eCollection 2021 Feb 01. PMID: 33732497; PMCID: PMC7947276.
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Operative Shutdown and Recovery: Restructuring Surgical Operations During the SARS-CoV-2 Pandemic.

The Journal of surgical research

McClelland PH, Cheng O, Hu J, Hunter JG, Winkler AC, Lee R, Zenilman ME.
PMID: 34333415
J Surg Res. 2021 Jun 16;268:181-189. doi: 10.1016/j.jss.2021.06.009. Epub 2021 Jun 16.

BACKGROUND: During the 2020 SARS-CoV-2 outbreak in New York City, hospitals canceled elective surgeries to increase capacity for critically ill patients. We present case volume data from our community hospital to demonstrate how this shutdown affected surgical care.METHODS: Between...

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McClelland PH, Cheng O, Hu J, et al. Operative Shutdown and Recovery: Restructuring Surgical Operations During the SARS-CoV-2 Pandemic. J Surg Res. 2021;268:181-189doi: 10.1016/j.jss.2021.06.009.
McClelland, P. H., Cheng, O., Hu, J., Hunter, J. G., Winkler, A. C., Lee, R., & Zenilman, M. E. (2021). Operative Shutdown and Recovery: Restructuring Surgical Operations During the SARS-CoV-2 Pandemic. The Journal of surgical research, 268181-189. https://doi.org/10.1016/j.jss.2021.06.009
McClelland, Paul H, et al. "Operative Shutdown and Recovery: Restructuring Surgical Operations During the SARS-CoV-2 Pandemic." The Journal of surgical research vol. 268 (2021): 181-189. doi: https://doi.org/10.1016/j.jss.2021.06.009
McClelland PH, Cheng O, Hu J, Hunter JG, Winkler AC, Lee R, Zenilman ME. Operative Shutdown and Recovery: Restructuring Surgical Operations During the SARS-CoV-2 Pandemic. J Surg Res. 2021 Jun 16;268:181-189. doi: 10.1016/j.jss.2021.06.009. Epub 2021 Jun 16. PMID: 34333415; PMCID: PMC8206585.
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MicroRNA-22 contributes to dexamethasone-induced osteoblast differentiation inhibition and dysfunction through targeting caveolin-3 expression in osteoblastic cells.

Experimental and therapeutic medicine

Li P, Mao W, Zhang S, Zhang L, Chen Z, Lu Z.
PMID: 33732309
Exp Ther Med. 2021 Apr;21(4):336. doi: 10.3892/etm.2021.9767. Epub 2021 Feb 08.

Osteoporosis is a common complication of long-term use of glucocorticoids (GCs) characterized by the loss of bone mass and damage of the microarchitecture as well as osteoblast dysfunction. Previous studies have demonstrated that microRNA-22 (miR-22) is the negative modulator...

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Li P, Mao W, Zhang S, et al. MicroRNA-22 contributes to dexamethasone-induced osteoblast differentiation inhibition and dysfunction through targeting caveolin-3 expression in osteoblastic cells. Exp Ther Med. 2021;21(4):336doi: 10.3892/etm.2021.9767.
Li, P., Mao, W., Zhang, S., Zhang, L., Chen, Z., & Lu, Z. (2021). MicroRNA-22 contributes to dexamethasone-induced osteoblast differentiation inhibition and dysfunction through targeting caveolin-3 expression in osteoblastic cells. Experimental and therapeutic medicine, 21(4), 336. https://doi.org/10.3892/etm.2021.9767
Li, Peng, et al. "MicroRNA-22 contributes to dexamethasone-induced osteoblast differentiation inhibition and dysfunction through targeting caveolin-3 expression in osteoblastic cells." Experimental and therapeutic medicine vol. 21,4 (2021): 336. doi: https://doi.org/10.3892/etm.2021.9767
Li P, Mao W, Zhang S, Zhang L, Chen Z, Lu Z. MicroRNA-22 contributes to dexamethasone-induced osteoblast differentiation inhibition and dysfunction through targeting caveolin-3 expression in osteoblastic cells. Exp Ther Med. 2021 Apr;21(4):336. doi: 10.3892/etm.2021.9767. Epub 2021 Feb 08. PMID: 33732309; PMCID: PMC7903452.
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Is the Capanna Technique a Reliable Method for Revision Surgery after Failure of Previous Limb-Salvage Surgery?.

Annals of surgical oncology

Li M, Xiao X, Fan J, Lu Y, Chen G, Huang M, Ji C, Wang Z, Li J.
PMID: 34341889
Ann Surg Oncol. 2021 Aug 02; doi: 10.1245/s10434-021-10506-z. Epub 2021 Aug 02.

BACKGROUND: Reconstruction of a massive bone defect caused by previous failed limb-salvage surgery in patients with bone sarcoma is challenging. Many procedures have been used, but they all have their inherent disadvantages. The Capanna technique has demonstrated good functional...

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Li M, Xiao X, Fan J, et al. Is the Capanna Technique a Reliable Method for Revision Surgery after Failure of Previous Limb-Salvage Surgery?. Ann Surg Oncol. 2021;doi: 10.1245/s10434-021-10506-z.
Li, M., Xiao, X., Fan, J., Lu, Y., Chen, G., Huang, M., Ji, C., Wang, Z., & Li, J. (2021). Is the Capanna Technique a Reliable Method for Revision Surgery after Failure of Previous Limb-Salvage Surgery?. Annals of surgical oncology, . https://doi.org/10.1245/s10434-021-10506-z
Li, Minghui, et al. "Is the Capanna Technique a Reliable Method for Revision Surgery after Failure of Previous Limb-Salvage Surgery?." Annals of surgical oncology vol. (2021). doi: https://doi.org/10.1245/s10434-021-10506-z
Li M, Xiao X, Fan J, Lu Y, Chen G, Huang M, Ji C, Wang Z, Li J. Is the Capanna Technique a Reliable Method for Revision Surgery after Failure of Previous Limb-Salvage Surgery?. Ann Surg Oncol. 2021 Aug 02; doi: 10.1245/s10434-021-10506-z. Epub 2021 Aug 02. PMID: 34341889.
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Application of a new percutaneous multi-function pedicle locator in minimally invasive spine surgery.

Scientific reports

Liu X, Liu H, Wang Y.
PMID: 34728727
Sci Rep. 2021 Nov 02;11(1):21451. doi: 10.1038/s41598-021-01027-6.

In this study, a new percutaneous multi-function pedicle locator was designed for personalized three-dimensional positioning of a pedicle in minimally invasive spine surgery (MISS) without computer-assisted navigation technology. The proposed locator was used in a number of patients during...

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Liu X, Liu H, Wang Y. Application of a new percutaneous multi-function pedicle locator in minimally invasive spine surgery. Sci Rep. 2021;11(1):21451doi: 10.1038/s41598-021-01027-6.
Liu, X., Liu, H., & Wang, Y. (2021). Application of a new percutaneous multi-function pedicle locator in minimally invasive spine surgery. Scientific reports, 11(1), 21451. https://doi.org/10.1038/s41598-021-01027-6
Liu, Xiaojian, et al. "Application of a new percutaneous multi-function pedicle locator in minimally invasive spine surgery." Scientific reports vol. 11,1 (2021): 21451. doi: https://doi.org/10.1038/s41598-021-01027-6
Liu X, Liu H, Wang Y. Application of a new percutaneous multi-function pedicle locator in minimally invasive spine surgery. Sci Rep. 2021 Nov 02;11(1):21451. doi: 10.1038/s41598-021-01027-6. PMID: 34728727; PMCID: PMC8563717.
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Showing 9985 to 9996 of 26054 entries