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Showing 109453 to 2808 of 2808 entries
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Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect.

Cureus

Alzahrani RA, Alzahrani OM, Alherz SH, Alzahrani AA, Alzahrani OM, Alqarni MA, Alzahrani KAA, Alzahrani KAH, Al Zahrani SA, Alzahrani AA, Alghamdi HA, Alshammari M.
PMID: 34917433
Cureus. 2021 Nov 13;13(11):e19551. doi: 10.7759/cureus.19551. eCollection 2021 Nov.

Methamphetamine is the second most commonly abused drug worldwide. It is a sympathomimetic agent that works by inhibiting the reuptake of monoamine neurotransmitters, including dopamine, norepinephrine, and serotonin. Methamphetamine use is associated with early mortality, and cardiovascular complications are...

Adverse Effects of Recreational and Medical Cannabis.

Psychopharmacology bulletin

Urits I, Charipova K, Gress K, Li N, Berger AA, Cornett EM, Kassem H, Ngo AL, Kaye AD, Viswanath O.
PMID: 33897066
Psychopharmacol Bull. 2021 Jan 12;51(1):94-109.

PURPOSE OF REVIEW: This comprehensive review discusses the adverse effects known today about marijuana, for either medical or recreational use. It reviews the role of cannabis in the treatment of chronic pain, cognitive and neurological adverse effects, special cases...

Manipulation of vocal communication and anxiety through pharmacologic modulation of norepinephrine in the Pink1-/- rat model of Parkinson disease.

Behavioural brain research

Hoffmeister JD, Kelm-Nelson CA, Ciucci MR.
PMID: 34755639
Behav Brain Res. 2022 Feb 10;418:113642. doi: 10.1016/j.bbr.2021.113642. Epub 2021 Oct 28.

Vocal deficits and anxiety are common, co-occurring, and interacting signs of Parkinson Disease (PD) that have a devastating impact on quality of life. Both manifest early in the disease process. Unlike hallmark motor signs of PD, neither respond adequately...

Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth.

Frontiers in cell and developmental biology

Zhang J, Chen R, Wen L, Fan Z, Guo Y, Hu Z, Miao Y.
PMID: 34513851
Front Cell Dev Biol. 2021 Aug 26;9:736738. doi: 10.3389/fcell.2021.736738. eCollection 2021.

Clinical observation and experimental studies have long suggested that the perifollicular nerves have nutritional and regulatory effects on the growth, development, and physiological cycle of hair follicles (HFs), even though the concrete mechanism remains obscure. Recently, with the progress...

Transcriptional analyses reveal different mechanism of toxicity for a chronic exposure to fluoxetine and venlafaxine on the brain of the marine fish Dicentrarchrus labrax.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP

Costa C, Semedo M, Machado SP, Cunha V, Ferreira M, Urbatzka R.
PMID: 34454087
Comp Biochem Physiol C Toxicol Pharmacol. 2021 Dec;250:109170. doi: 10.1016/j.cbpc.2021.109170. Epub 2021 Aug 25.

Selective serotonin reuptake inhibitor (SSRI) and serotonin norepinephrine reuptake inhibitor (SNRI) are prescribed for clinical depression and detected in aquatic ecosystems. The main aim of this study was to explore and evaluate transcriptional responses of neurotransmitter genes in the...

Quantitative sensory testing predicts histological small fiber neuropathy in postural tachycardia syndrome.

Neurology. Clinical practice

Billig SCI, Schauermann JC, Rolke R, Katona I, Schulz JB, Maier A.
PMID: 33299671
Neurol Clin Pract. 2020 Oct;10(5):428-434. doi: 10.1212/CPJ.0000000000000770.

BACKGROUND: Retrospective investigation of the somatosensory profile and prediction of histologic small fiber neuropathy (SFN) in postural orthostatic tachycardia syndrome (POTS) was performed using quantitative sensory testing (QST) as a standardized noninvasive test.METHODS: In this investigation, full data sets...

High mean arterial pressure target to improve sepsis-associated acute kidney injury in patients with prior hypertension: a feasibility study.

Annals of intensive care

Dewitte A, Labat A, Duvignaud PA, Bouche G, Joannes-Boyau O, Ripoche J, Hilbert G, Gruson D, Rubin S, Ouattara A, Boyer A, Combe C.
PMID: 34553274
Ann Intensive Care. 2021 Sep 22;11(1):139. doi: 10.1186/s13613-021-00925-2.

BACKGROUND: The optimal mean arterial pressure (MAP) in cases of septic shock is still a matter of debate in patients with prior hypertension. An MAP between 75 and 85 mmHg can improve glomerular filtration rate (GFR) but its effect...

Excitation-emission fluorescence matrix acquired from glutathione capped CdSeS/ZnS quantum dots in combination with chemometric tools for pattern-based sensing of neurotransmitters.

Mikrochimica acta

Głowacz K, Drozd M, Ciosek-Skibińska P.
PMID: 34524529
Mikrochim Acta. 2021 Sep 15;188(10):343. doi: 10.1007/s00604-021-04984-x.

The presented work concerns pattern-based sensing with quantum dots for the identification and quantification of neurotransmitters by means of excitation-emission fluorescence spectroscopy (2D fluorescence). In the framework of this study, glutathione capped CdSeS/ZnS nanocrystals were used as non-specific nanoreceptors...

Circulating biomarkers associated with performance and resilience during military operational stress.

European journal of sport science

Beckner ME, Main L, Tait JL, Martin BJ, Conkright WR, Nindl BC.
PMID: 34346851
Eur J Sport Sci. 2021 Aug 17;1-15. doi: 10.1080/17461391.2021.1962983. Epub 2021 Aug 17.

Adaptation to military operational stress is a complex physiological response that calls upon the sympathetic nervous system (SNS), hypothalamic pituitary adrenal (HPA) axis and immune system, to create a delicate balance between anabolism and catabolism and meet the demands...

[Antidepressive agents and hypertension: A case/no-case study in French pharmacovigilance database].

L'Encephale

Hofferer A, Dolladille C, Chretien B, Sassier M, Laugier D, Atzenhoffer M, Bagheri H, Alexandre J, Fedrizzi S, Humbert X.
PMID: 34311965
Encephale. 2021 Jul 23; doi: 10.1016/j.encep.2021.04.009. Epub 2021 Jul 23.

INTRODUCTION: Drug-induced hypertension was described with several pharmacological classes. The association between hypertension and antidepressant drugs (AD) is controversial. The objective of this study was to evaluate the link between hypertension and ADs.MATERIALS AND METHODS: A retrospective disproportionality analysis...

Physical compatibility of Normosol-R with critical care medications used in patients with COVID-19 during simulated Y-site administration.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Holyk AA, Lindner AH, Lindner SE, Shippert BW.
PMID: 34390244
Am J Health Syst Pharm. 2022 Jan 01;79(1):e27-e33. doi: 10.1093/ajhp/zxab329.

PURPOSE: Guidelines from the National Institutes of Health support the use of balanced crystalloid solutions such as Normosol-R (Hospira, Lake Forest, IL) for patients with coronavirus disease 2019 (COVID-19). However, their clinical utility is hindered by a lack of...

Synthesis and analysis of dihydrotetrabenazine derivatives as novel vesicular monoamine transporter 2 inhibitors.

European journal of medicinal chemistry

Yang Y, Yu D, Zhu X, Du G, Wang W, Zou F, Wang H, Zhang R, Ye L, Tian J.
PMID: 34329999
Eur J Med Chem. 2021 Nov 15;224:113718. doi: 10.1016/j.ejmech.2021.113718. Epub 2021 Jul 24.

Vesicular monoamine transporter 2 (VMAT2) is essential for synaptic transmission of all biogenic amines in the brain including serotonin, norepinephrine, histamine, and dopamine (DA). Given its crucial role in the neurophysiology and pharmacology of the central nervous system, VMAT2...

Showing 109453 to 2808 of 2808 entries