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Showing 25 to 36 of 2808 entries
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Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support.

Intensive care medicine experimental

Suffredini DA, Cui X, Jaswal D, Remy KE, Li Y, Sun J, Solomon SB, Fitz Y, Moayeri M, Leppla S, Eichacker PQ.
PMID: 29058092
Intensive Care Med Exp. 2017 Oct 23;5(1):48. doi: 10.1186/s40635-017-0159-9.

BACKGROUND: Although anthrax immune globulin (AIG) improved survival in antibiotic-treated Bacillus anthracis-challenged animal models, whether it adds to the benefit of conventional hemodynamic support for B. anthracis toxin-associated shock is unknown.METHODS: We therefore tested AIG in sedated, mechanically ventilated...

Effects of Prenatal Cocaine Exposure on Serotonin and Norepinephrine Transporter Density in the Rat Brain.

Annals of the New York Academy of Sciences

McREYNOLDS AM, Meyer JS.
PMID: 29087608
Ann N Y Acad Sci. 1998 Jun;846(1):412-414. doi: 10.1111/j.1749-6632.1998.tb09768.x.

No abstract available.

Designing modulators of monoamine transporters using virtual screening techniques.

Frontiers in pharmacology

Mortensen OV, Kortagere S.
PMID: 26483692
Front Pharmacol. 2015 Sep 29;6:223. doi: 10.3389/fphar.2015.00223. eCollection 2015.

The plasma-membrane monoamine transporters (MATs), including the serotonin (SERT), norepinephrine (NET) and dopamine (DAT) transporters, serve a pivotal role in limiting monoamine-mediated neurotransmission through the reuptake of their respective monoamine neurotransmitters. The transporters are the main target of clinically...

Adjunctive Trazodone and Depression Outcome in Adolescents Treated with Serotonin Re-uptake Inhibitors.

Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent

Sultan MA, Courtney DB.
PMID: 29056986
J Can Acad Child Adolesc Psychiatry. 2017;26(3):233-240. Epub 2017 Oct 01.

OBJECTIVES: Recent published evidence suggests that adjunctive trazodone treatment may limit serotonin reuptake inhibitor (SRI) response in depressed adolescents in the context of a controlled trial. This study examined the effects of adjunctive trazodone on depression outcome in adolescents...

Effect of the sympathetic nervous system co-transmitters ATP and norepinephrine on thermoregulatory response to cooling.

Temperature (Austin, Tex.)

Kozyreva TV, Meyta ES, Khramova GM.
PMID: 27227010
Temperature (Austin). 2015 Feb 27;2(1):121-8. doi: 10.1080/23328940.2014.1000705. eCollection 2015.

The existence of co-transmitters of the sympathetic nervous system norepinephrine (NE) and ATP implies variations in the neuromodulator mechanisms of physiological processes. The role of ATP, as a transmitter of the peripheral part of sympathetic nervous system in the...

Korean Guidelines for the Pharmacological Treatment of Social Anxiety Disorder: Initial Treatment Strategies.

Psychiatry investigation

Yoon H, Oh DJ, Suh HS, Lee KU, Lim SW, Lee JY, Yang JC, Lee JH, Ha J, Lee BH, Kang SG, Yoon HK, Moon J, Bae SM, Kwon Y, Kim HC, Oh KS.
PMID: 29475215
Psychiatry Investig. 2018 Feb;15(2):147-155. doi: 10.30773/pi.2017.05.01. Epub 2017 Nov 29.

OBJECTIVE: The aim of the present study was to provide clinical consensus and evidence regarding initial treatment strategies for the pharmacological treatment of social anxiety disorder (SAD) in Korea.METHODS: We prepared a questionnaire to derive a consensus from clinicians...

Vasopressin use in critically ill cirrhosis patients with catecholamine-resistant septic shock: The CVICU cohort.

World journal of hepatology

Myc LA, Stine JG, Chakrapani R, Kadl A, Argo CK.
PMID: 28144392
World J Hepatol. 2017 Jan 18;9(2):106-113. doi: 10.4254/wjh.v9.i2.106.

AIM: To examine patient-centered outcomes with vasopressin (AVP) use in patients with cirrhosis with catecholamine-refractory septic shock.METHODS: We conducted a single center, retrospective cohort study enrolling adult patients with cirrhosis treated for catecholamine-resistant septic shock in the intensive care...

Effects of valproic acid on sympathetic activity and left ventricularmyocardial remodelling in rats during pressure overload.

Turkish journal of medical sciences

Liu Y, Li S, Zhang Z, Lv Z, Jiang H, Tan X, Liu F.
PMID: 29152949
Turk J Med Sci. 2017 Nov 13;47(5):1651-1660. doi: 10.3906/sag-1704-142.

Background/aim: Pressure overload induces cardiac remodelling and results in heart failure. Enhanced sympathetic outflow participates in the development of cardiac remodelling for the duration of pressure overload as an independent factor. Valproic acid has recently been shown to reduce...

Beyond Sensation Seeking: A Conceptual Framework for Individual Differences in Psychostimulant Drug Effects in Healthy Humans.

Current opinion in behavioral sciences

White TL.
PMID: 28111627
Curr Opin Behav Sci. 2017 Feb;13:63-70. doi: 10.1016/j.cobeha.2016.10.008.

Psychostimulant addiction is an important, relapsing condition for which there is no effective pharmacological treatment. Countering this problem requires an understanding of the specific risk factors that predispose individuals to initial misuse of these drugs. Healthy individuals display marked...

Critical Management of Severe Hypotension Caused by Amlodipine Toxicity Managed With Hyperinsulinemia/Euglycemia Therapy Supplemented With Calcium Gluconate, Intravenous Glucagon and Other Vasopressor Support: Review of Literature.

Cardiology research

Kumar K, Biyyam M, Bajantri B, Nayudu S.
PMID: 29479386
Cardiol Res. 2018 Feb;9(1):46-49. doi: 10.14740/cr646w. Epub 2018 Feb 11.

Calcium channel blocker (CCB ) overdose, whether intentional or accidental, is a common clinical scenario and can be very lethal. Conventional treatments for CCB overdose include intravenous (IV) fluids, calcium salts, dopamine, dobutamine, norepinephrine, phosphodiesterase inhibitors, and glucagon. However,...

Urinary neurotransmitter testing: considerations of spot baseline norepinephrine and epinephrine.

Open access journal of urology

Hinz M, Stein A, Uncini T.
PMID: 24198631
Open Access J Urol. 2011 Feb 04;3:19-24. doi: 10.2147/OAJU.S16637. eCollection 2011.

BACKGROUND: The purpose of this paper is to present the results of statistical analysis of spot baseline urinary norepinephrine and epinephrine assays in correlation with spot baseline urinary serotonin and dopamine findings previously published by the authors. Our research...

Computational Study of the pKa Values of Potential Catalytic Residues in the Active Site of Monoamine Oxidase B.

Journal of chemical theory and computation

Borštnar R, Repič M, Kamerlin SC, Vianello R, Mavri J.
PMID: 26593027
J Chem Theory Comput. 2012 Oct 09;8(10):3864-70. doi: 10.1021/ct300119u. Epub 2012 Apr 25.

Monoamine oxidase (MAO), which exists in two isozymic forms, MAO A and MAO B, is an important flavoenzyme responsible for the metabolism of amine neurotransmitters such as dopamine, serotonin, and norepinephrine. Despite extensive research effort, neither the catalytic nor...

Showing 25 to 36 of 2808 entries