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The antidepressant venlafaxine perturbs cardiac development and function in larval zebrafish.

Aquatic toxicology (Amsterdam, Netherlands)

Thompson WA, Shvartsburd Z, Vijayan MM.
PMID: 34856460
Aquat Toxicol. 2021 Nov 22;242:106041. doi: 10.1016/j.aquatox.2021.106041. Epub 2021 Nov 22.

Venlafaxine, a selective serotonin and norepinephrine reuptake inhibitor, is a highly prescribed antidepressant and is detected at µg/L concentrations in waterways receiving municipal wastewater effluents. We previously showed that early-life venlafaxine exposure disrupted the normal development of the nervous...

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Thompson WA, Shvartsburd Z, Vijayan MM. The antidepressant venlafaxine perturbs cardiac development and function in larval zebrafish. Aquat Toxicol. 2021;242:106041doi: 10.1016/j.aquatox.2021.106041.
Thompson, W. A., Shvartsburd, Z., & Vijayan, M. M. (2021). The antidepressant venlafaxine perturbs cardiac development and function in larval zebrafish. Aquatic toxicology (Amsterdam, Netherlands), 242106041. https://doi.org/10.1016/j.aquatox.2021.106041
Thompson, W Andrew, et al. "The antidepressant venlafaxine perturbs cardiac development and function in larval zebrafish." Aquatic toxicology (Amsterdam, Netherlands) vol. 242 (2021): 106041. doi: https://doi.org/10.1016/j.aquatox.2021.106041
Thompson WA, Shvartsburd Z, Vijayan MM. The antidepressant venlafaxine perturbs cardiac development and function in larval zebrafish. Aquat Toxicol. 2021 Nov 22;242:106041. doi: 10.1016/j.aquatox.2021.106041. Epub 2021 Nov 22. PMID: 34856460.
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Hydroxocobalamin or Methylene Blue for Vasoplegic Syndrome in Adult Cardiothoracic Surgery.

Journal of cardiothoracic and vascular anesthesia

Kram SJ, Kram BL, Cook JC, Ohman KL, Ghadimi K.
PMID: 34176677
J Cardiothorac Vasc Anesth. 2022 Feb;36(2):469-476. doi: 10.1053/j.jvca.2021.05.042. Epub 2021 May 27.

OBJECTIVE: To compare hydroxocobalamin and methylene blue for the treatment of vasopressor-refractory vasoplegic syndrome (VS) after adult cardiac surgery with cardiopulmonary bypass (CPB).DESIGN: A retrospective, propensity-matched, cohort study was performed. The primary endpoints were the percentage change in vasopressor...

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Kram SJ, Kram BL, Cook JC, et al. Hydroxocobalamin or Methylene Blue for Vasoplegic Syndrome in Adult Cardiothoracic Surgery. J Cardiothorac Vasc Anesth. 2021;36(2):469-476doi: 10.1053/j.jvca.2021.05.042.
Kram, S. J., Kram, B. L., Cook, J. C., Ohman, K. L., & Ghadimi, K. (2022). Hydroxocobalamin or Methylene Blue for Vasoplegic Syndrome in Adult Cardiothoracic Surgery. Journal of cardiothoracic and vascular anesthesia, 36(2), 469-476. https://doi.org/10.1053/j.jvca.2021.05.042
Kram, Shawn J, et al. "Hydroxocobalamin or Methylene Blue for Vasoplegic Syndrome in Adult Cardiothoracic Surgery." Journal of cardiothoracic and vascular anesthesia vol. 36,2 (2022): 469-476. doi: https://doi.org/10.1053/j.jvca.2021.05.042
Kram SJ, Kram BL, Cook JC, Ohman KL, Ghadimi K. Hydroxocobalamin or Methylene Blue for Vasoplegic Syndrome in Adult Cardiothoracic Surgery. J Cardiothorac Vasc Anesth. 2022 Feb;36(2):469-476. doi: 10.1053/j.jvca.2021.05.042. Epub 2021 May 27. PMID: 34176677.
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A role of the norepinephrine system or effort in the interplay of different facets of inhibitory control.

Neuropsychologia

Yu S, Ghin F, Mückschel M, Ziemssen T, Stock AK, Beste C.
PMID: 34998865
Neuropsychologia. 2022 Jan 05;166:108143. doi: 10.1016/j.neuropsychologia.2022.108143. Epub 2022 Jan 05.

Inhibitory control has multiple facets, and one possible distinction can be made between 'inhibition of interferences' and the 'inhibition of actions'. Both facets of inhibitory control show an interdependency. Even though some neurophysiological processes underlying this interdependency have been...

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Yu S, Ghin F, Mückschel M, et al. A role of the norepinephrine system or effort in the interplay of different facets of inhibitory control. Neuropsychologia. 2022;166:108143doi: 10.1016/j.neuropsychologia.2022.108143.
Yu, S., Ghin, F., Mückschel, M., Ziemssen, T., Stock, A. K., & Beste, C. (2022). A role of the norepinephrine system or effort in the interplay of different facets of inhibitory control. Neuropsychologia, 166108143. https://doi.org/10.1016/j.neuropsychologia.2022.108143
Yu, Shijing, et al. "A role of the norepinephrine system or effort in the interplay of different facets of inhibitory control." Neuropsychologia vol. 166 (2022): 108143. doi: https://doi.org/10.1016/j.neuropsychologia.2022.108143
Yu S, Ghin F, Mückschel M, Ziemssen T, Stock AK, Beste C. A role of the norepinephrine system or effort in the interplay of different facets of inhibitory control. Neuropsychologia. 2022 Jan 05;166:108143. doi: 10.1016/j.neuropsychologia.2022.108143. Epub 2022 Jan 05. PMID: 34998865.
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The Sympathetic Nervous System in Hypertension: Roadmap Update of a Long Journey.

American journal of hypertension

Grassi G.
PMID: 34355740
Am J Hypertens. 2021 Dec 01;34(12):1247-1254. doi: 10.1093/ajh/hpab124.

The present paper will provide an update on the role of sympathetic neural factors in the development and progression of essential hypertension by reviewing data collected in the past 10 years. This will be done by discussing the results...

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Grassi G. The Sympathetic Nervous System in Hypertension: Roadmap Update of a Long Journey. Am J Hypertens. 2021;34(12):1247-1254doi: 10.1093/ajh/hpab124.
Grassi, G. (2021). The Sympathetic Nervous System in Hypertension: Roadmap Update of a Long Journey. American journal of hypertension, 34(12), 1247-1254. https://doi.org/10.1093/ajh/hpab124
Grassi, Guido. "The Sympathetic Nervous System in Hypertension: Roadmap Update of a Long Journey." American journal of hypertension vol. 34,12 (2021): 1247-1254. doi: https://doi.org/10.1093/ajh/hpab124
Grassi G. The Sympathetic Nervous System in Hypertension: Roadmap Update of a Long Journey. Am J Hypertens. 2021 Dec 01;34(12):1247-1254. doi: 10.1093/ajh/hpab124. PMID: 34355740; PMCID: PMC8643601.
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Analysis of standard concentrations of continuous infusions in nine Spanish neonatal intensive care units.

European journal of hospital pharmacy : science and practice

De Basagoiti A, Antón X, Calleja A, De Miguel M, Guerra E, Loureiro B, Campino A.
PMID: 32554526
Eur J Hosp Pharm. 2022 Jan;29(1):50-54. doi: 10.1136/ejhpharm-2019-002194. Epub 2020 Jun 17.

OBJECTIVES: The aim of this study was to describe the use of standard concentrations for continuous infusion drugs in Spanish neonatal intensive care units (NICUs).METHODS: We conducted an observational multicentre study based on a survey sent by email to...

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De Basagoiti A, Antón X, Calleja A, et al. Analysis of standard concentrations of continuous infusions in nine Spanish neonatal intensive care units. Eur J Hosp Pharm. 2020;29(1):50-54doi: 10.1136/ejhpharm-2019-002194.
De Basagoiti, A., Antón, X., Calleja, A., De Miguel, M., Guerra, E., Loureiro, B., & Campino, A. (2022). Analysis of standard concentrations of continuous infusions in nine Spanish neonatal intensive care units. European journal of hospital pharmacy : science and practice, 29(1), 50-54. https://doi.org/10.1136/ejhpharm-2019-002194
De Basagoiti, Amaya, et al. "Analysis of standard concentrations of continuous infusions in nine Spanish neonatal intensive care units." European journal of hospital pharmacy : science and practice vol. 29,1 (2022): 50-54. doi: https://doi.org/10.1136/ejhpharm-2019-002194
De Basagoiti A, Antón X, Calleja A, De Miguel M, Guerra E, Loureiro B, Campino A. Analysis of standard concentrations of continuous infusions in nine Spanish neonatal intensive care units. Eur J Hosp Pharm. 2022 Jan;29(1):50-54. doi: 10.1136/ejhpharm-2019-002194. Epub 2020 Jun 17. PMID: 32554526; PMCID: PMC8717789.
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Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease.

Behavioural brain research

Hoffmeister JD, Kelm-Nelson CA, Ciucci MR.
PMID: 34358571
Behav Brain Res. 2021 Sep 24;414:113514. doi: 10.1016/j.bbr.2021.113514. Epub 2021 Aug 04.

Vocal communication impairment and anxiety are co-occurring and interacting signs of Parkinson Disease (PD) that are common, poorly understood, and under-treated. Both vocal communication and anxiety are influenced by the noradrenergic system. In light of this shared neural substrate...

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Hoffmeister JD, Kelm-Nelson CA, Ciucci MR. Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease. Behav Brain Res. 2021;414:113514doi: 10.1016/j.bbr.2021.113514.
Hoffmeister, J. D., Kelm-Nelson, C. A., & Ciucci, M. R. (2021). Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease. Behavioural brain research, 414113514. https://doi.org/10.1016/j.bbr.2021.113514
Hoffmeister, Jesse D, et al. "Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease." Behavioural brain research vol. 414 (2021): 113514. doi: https://doi.org/10.1016/j.bbr.2021.113514
Hoffmeister JD, Kelm-Nelson CA, Ciucci MR. Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease. Behav Brain Res. 2021 Sep 24;414:113514. doi: 10.1016/j.bbr.2021.113514. Epub 2021 Aug 04. PMID: 34358571; PMCID: PMC8393386.
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Spared performance but increased uncertainty in schizophrenia: Evidence from a probabilistic decision-making task.

Schizophrenia research

Kreis I, Zhang L, Moritz S, Pfuhl G.
PMID: 34272122
Schizophr Res. 2021 Jul 13; doi: 10.1016/j.schres.2021.06.038. Epub 2021 Jul 13.

Aberrant attribution of salience to in fact little informative events might explain the emergence of positive symptoms in schizophrenia and has been linked to belief uncertainty. Uncertainty is thought to be encoded by neuromodulators, including norepinephrine. However, norepinephrinergic encoding...

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Kreis I, Zhang L, Moritz S, et al. Spared performance but increased uncertainty in schizophrenia: Evidence from a probabilistic decision-making task. Schizophr Res. 2021;doi: 10.1016/j.schres.2021.06.038.
Kreis, I., Zhang, L., Moritz, S., & Pfuhl, G. (2021). Spared performance but increased uncertainty in schizophrenia: Evidence from a probabilistic decision-making task. Schizophrenia research, . https://doi.org/10.1016/j.schres.2021.06.038
Kreis, Isabel, et al. "Spared performance but increased uncertainty in schizophrenia: Evidence from a probabilistic decision-making task." Schizophrenia research vol. (2021). doi: https://doi.org/10.1016/j.schres.2021.06.038
Kreis I, Zhang L, Moritz S, Pfuhl G. Spared performance but increased uncertainty in schizophrenia: Evidence from a probabilistic decision-making task. Schizophr Res. 2021 Jul 13; doi: 10.1016/j.schres.2021.06.038. Epub 2021 Jul 13. PMID: 34272122.
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Immunoreactivity of Muscarinic Acetylcholine M2 and Serotonin 5-HT2B Receptors, Norepinephrine Transporter and Kir Channels in a Model of Epilepsy.

Life (Basel, Switzerland)

Akyuz E, Doganyigit Z, Paudel YN, Koklu B, Kaymak E, Villa C, Arulsamy A, Shaikh MF, Devinsky O.
PMID: 33810231
Life (Basel). 2021 Mar 26;11(4). doi: 10.3390/life11040276.

Epilepsy is characterized by an imbalance in neurotransmitter activity; an increased excitatory to an inhibitory activity. Acetylcholine (ACh), serotonin, and norepinephrine (NE) may modulate neural activity via several mechanisms, mainly through its receptors/transporter activity and alterations in the extracellular...

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Akyuz E, Doganyigit Z, Paudel YN, et al. Immunoreactivity of Muscarinic Acetylcholine M2 and Serotonin 5-HT2B Receptors, Norepinephrine Transporter and Kir Channels in a Model of Epilepsy. Life (Basel). 2021;11(4)doi: 10.3390/life11040276.
Akyuz, E., Doganyigit, Z., Paudel, Y. N., Koklu, B., Kaymak, E., Villa, C., Arulsamy, A., Shaikh, M. F., & Devinsky, O. (2021). Immunoreactivity of Muscarinic Acetylcholine M2 and Serotonin 5-HT2B Receptors, Norepinephrine Transporter and Kir Channels in a Model of Epilepsy. Life (Basel, Switzerland), 11(4), . https://doi.org/10.3390/life11040276
Akyuz, Enes, et al. "Immunoreactivity of Muscarinic Acetylcholine M2 and Serotonin 5-HT2B Receptors, Norepinephrine Transporter and Kir Channels in a Model of Epilepsy." Life (Basel, Switzerland) vol. 11,4 (2021). doi: https://doi.org/10.3390/life11040276
Akyuz E, Doganyigit Z, Paudel YN, Koklu B, Kaymak E, Villa C, Arulsamy A, Shaikh MF, Devinsky O. Immunoreactivity of Muscarinic Acetylcholine M2 and Serotonin 5-HT2B Receptors, Norepinephrine Transporter and Kir Channels in a Model of Epilepsy. Life (Basel). 2021 Mar 26;11(4). doi: 10.3390/life11040276. PMID: 33810231; PMCID: PMC8066555.
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Arterial Load and Norepinephrine Are Associated With the Response of the Cardiovascular System to Fluid Expansion.

Frontiers in physiology

Nguyen M, Mallat J, Marc J, Abou-Arab O, Bouhemad B, Guinot PG.
PMID: 34421648
Front Physiol. 2021 Aug 04;12:707832. doi: 10.3389/fphys.2021.707832. eCollection 2021.

BACKGROUND: Fluid responsiveness has been extensively studied by using the preload prism. The arterial load might be a factor modulating the fluid responsiveness. The norepinephrine (NE) administration increases the arterial load and modifies the vascular properties. The objective of...

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Nguyen M, Mallat J, Marc J, et al. Arterial Load and Norepinephrine Are Associated With the Response of the Cardiovascular System to Fluid Expansion. Front Physiol. 2021;12:707832doi: 10.3389/fphys.2021.707832.
Nguyen, M., Mallat, J., Marc, J., Abou-Arab, O., Bouhemad, B., & Guinot, P. G. (2021). Arterial Load and Norepinephrine Are Associated With the Response of the Cardiovascular System to Fluid Expansion. Frontiers in physiology, 12707832. https://doi.org/10.3389/fphys.2021.707832
Nguyen, Maxime, et al. "Arterial Load and Norepinephrine Are Associated With the Response of the Cardiovascular System to Fluid Expansion." Frontiers in physiology vol. 12 (2021): 707832. doi: https://doi.org/10.3389/fphys.2021.707832
Nguyen M, Mallat J, Marc J, Abou-Arab O, Bouhemad B, Guinot PG. Arterial Load and Norepinephrine Are Associated With the Response of the Cardiovascular System to Fluid Expansion. Front Physiol. 2021 Aug 04;12:707832. doi: 10.3389/fphys.2021.707832. eCollection 2021. PMID: 34421648; PMCID: PMC8371483.
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Severe dysautonomia in glycine receptor antibody-positive progressive encephalomyelitis with rigidity and myoclonus (PERM): A case report.

Autonomic neuroscience : basic & clinical

Mizutani Y, Adachi S, Nakano S, Hayashi K, Higashi A, Kikuchi K, Maeda T, Murate K, Shima S, Iizuka T, Ueda A, Ito M, Watanabe H.
PMID: 34801829
Auton Neurosci. 2021 Nov 16;237:102910. doi: 10.1016/j.autneu.2021.102910. Epub 2021 Nov 16.

Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a severe form of stiff-person spectrum disorder. We report a 59-year-old man who presented with progressive encephalomyelitis causing diplopia, bulbar palsy, severe dysautonomia, followed by stiffness and myoclonic cluster. Laboratory tests...

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Mizutani Y, Adachi S, Nakano S, et al. Severe dysautonomia in glycine receptor antibody-positive progressive encephalomyelitis with rigidity and myoclonus (PERM): A case report. Auton Neurosci. 2021;237:102910doi: 10.1016/j.autneu.2021.102910.
Mizutani, Y., Adachi, S., Nakano, S., Hayashi, K., Higashi, A., Kikuchi, K., Maeda, T., Murate, K., Shima, S., Iizuka, T., Ueda, A., Ito, M., & Watanabe, H. (2021). Severe dysautonomia in glycine receptor antibody-positive progressive encephalomyelitis with rigidity and myoclonus (PERM): A case report. Autonomic neuroscience : basic & clinical, 237102910. https://doi.org/10.1016/j.autneu.2021.102910
Mizutani, Yasuaki, et al. "Severe dysautonomia in glycine receptor antibody-positive progressive encephalomyelitis with rigidity and myoclonus (PERM): A case report." Autonomic neuroscience : basic & clinical vol. 237 (2021): 102910. doi: https://doi.org/10.1016/j.autneu.2021.102910
Mizutani Y, Adachi S, Nakano S, Hayashi K, Higashi A, Kikuchi K, Maeda T, Murate K, Shima S, Iizuka T, Ueda A, Ito M, Watanabe H. Severe dysautonomia in glycine receptor antibody-positive progressive encephalomyelitis with rigidity and myoclonus (PERM): A case report. Auton Neurosci. 2021 Nov 16;237:102910. doi: 10.1016/j.autneu.2021.102910. Epub 2021 Nov 16. PMID: 34801829.
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Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats.

Evidence-based complementary and alternative medicine : eCAM

Luo C, Fan H, Li S, Zou Y.
PMID: 33833815
Evid Based Complement Alternat Med. 2021 Mar 26;2021:5570356. doi: 10.1155/2021/5570356. eCollection 2021.

This study aimed to investigate the therapeutic effects of candesartan combined with music therapy on diabetic retinopathy with depression and to assess the molecular mechanisms. Associated animal model of diabetes mellitus and depression was established in rats. Pathological changes...

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Luo C, Fan H, Li S, et al. Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats. Evid Based Complement Alternat Med. 2021;2021:5570356doi: 10.1155/2021/5570356.
Luo, C., Fan, H., Li, S., & Zou, Y. (2021). Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats. Evidence-based complementary and alternative medicine : eCAM, 20215570356. https://doi.org/10.1155/2021/5570356
Luo, Chengping, et al. "Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats." Evidence-based complementary and alternative medicine : eCAM vol. 2021 (2021): 5570356. doi: https://doi.org/10.1155/2021/5570356
Luo C, Fan H, Li S, Zou Y. Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats. Evid Based Complement Alternat Med. 2021 Mar 26;2021:5570356. doi: 10.1155/2021/5570356. eCollection 2021. PMID: 33833815; PMCID: PMC8018856.
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Behavioral and hypothalamic transcriptome analyses reveal sex-specific responses to phenanthrene exposure in the fathead minnow (Pimephales promelas).

Comparative biochemistry and physiology. Part D, Genomics & proteomics

Loughery JR, Crowley E, Kidd KA, Martyniuk CJ.
PMID: 34500131
Comp Biochem Physiol Part D Genomics Proteomics. 2021 Dec;40:100905. doi: 10.1016/j.cbd.2021.100905. Epub 2021 Aug 24.

Environmental concentrations of the polycyclic aromatic hydrocarbon phenanthrene can become elevated with petroleum processing, industrial activities, and urban run-off into waterbodies. However, mechanisms related to its neurotoxicity in fish are not fully described. Here, we exposed adult fathead minnows...

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Loughery JR, Crowley E, Kidd KA, et al. Behavioral and hypothalamic transcriptome analyses reveal sex-specific responses to phenanthrene exposure in the fathead minnow (Pimephales promelas). Comp Biochem Physiol Part D Genomics Proteomics. 2021;40:100905doi: 10.1016/j.cbd.2021.100905.
Loughery, J. R., Crowley, E., Kidd, K. A., & Martyniuk, C. J. (2021). Behavioral and hypothalamic transcriptome analyses reveal sex-specific responses to phenanthrene exposure in the fathead minnow (Pimephales promelas). Comparative biochemistry and physiology. Part D, Genomics & proteomics, 40100905. https://doi.org/10.1016/j.cbd.2021.100905
Loughery, Jennifer R, et al. "Behavioral and hypothalamic transcriptome analyses reveal sex-specific responses to phenanthrene exposure in the fathead minnow (Pimephales promelas)." Comparative biochemistry and physiology. Part D, Genomics & proteomics vol. 40 (2021): 100905. doi: https://doi.org/10.1016/j.cbd.2021.100905
Loughery JR, Crowley E, Kidd KA, Martyniuk CJ. Behavioral and hypothalamic transcriptome analyses reveal sex-specific responses to phenanthrene exposure in the fathead minnow (Pimephales promelas). Comp Biochem Physiol Part D Genomics Proteomics. 2021 Dec;40:100905. doi: 10.1016/j.cbd.2021.100905. Epub 2021 Aug 24. PMID: 34500131.
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Showing 2773 to 2784 of 2808 entries