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Showing 13 to 24 of 2808 entries
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Voltage-Sensitive K(+) Channels Inhibit Parasympathetic Ganglion Transmission and Vagal Control of Heart Rate in Hypertensive Rats.

Frontiers in neurology

Berg T.
PMID: 26696959
Front Neurol. 2015 Dec 08;6:260. doi: 10.3389/fneur.2015.00260. eCollection 2015.

Parasympathetic withdrawal plays an important role in the autonomic dysfunctions in hypertension. Since hyperpolarizing, voltage-sensitive K(+) channels (K V) hamper transmitter release, elevated K V-activity may explain the disturbed vagal control of heart rate (HR) in hypertension. Here, the...

Overactive Bladder Successfully Treated with Duloxetine in a Female Adolescent.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Wang SM, Lee HK, Kweon YS, Lee CT, Lee KU.
PMID: 26243851
Clin Psychopharmacol Neurosci. 2015 Aug 31;13(2):212-4. doi: 10.9758/cpn.2015.13.2.212.

Overactive bladder (OAB) is defined as urgency, usually with frequency and nocturia, and with or without urge incontinence. Duloxetine, an antidepressant that inhibits reuptake of serotonin and norepinephrine, is indicated for the treatment of stress urinary incontinence in Europe....

Inhibition of Cytochrome P450 by Propolis in Human Liver Microsomes.

Toxicological research

Ryu CS, Oh SJ, Oh JM, Lee JY, Lee SY, Chae JW, Kwon KI, Kim SK.
PMID: 27437087
Toxicol Res. 2016 Jul;32(3):207-13. doi: 10.5487/TR.2016.32.3.207. Epub 2016 Jul 30.

Although propolis is one of the most popular functional foods for human health, there have been no comprehensive studies of herb-drug interactions through cytochrome P450 (CYP) inhibition. The purpose of this study was to determine the inhibitory effects of...

High natural killer cell number might identify stroke patients at risk of developing infections.

Neurology(R) neuroimmunology & neuroinflammation

De Raedt S, De Vos A, Van Binst AM, De Waele M, Coomans D, Buyl R, De Keyser J.
PMID: 25738168
Neurol Neuroimmunol Neuroinflamm. 2015 Feb 12;2(2):e71. doi: 10.1212/NXI.0000000000000071. eCollection 2015 Apr.

OBJECTIVE: To investigate early changes in leukocyte subsets and autonomic function as predictors of the development of poststroke infections.METHODS: We assessed the time course of leukocyte subsets in the blood of 59 patients with acute ischemic stroke. We divided...

Acupuncture for visceral pain: neural substrates and potential mechanisms.

Evidence-based complementary and alternative medicine : eCAM

Chen S, Wang S, Rong P, Wang J, Qiao L, Feng X, Liu J, Zhang J.
PMID: 25614752
Evid Based Complement Alternat Med. 2014;2014:609594. doi: 10.1155/2014/609594. Epub 2014 Dec 29.

Visceral pain is the most common form of pain caused by varied diseases and a major reason for patients to seek medical consultation. Despite much advances, the pathophysiological mechanism is still poorly understood comparing with its somatic counterpart and,...

Plasma concentrations of adrenomedullin and atrial and brain natriuretic peptides in patients with adrenal pheochromocytoma.

Oncology letters

Hu W, Shi L, Zhou PH, Zhang XB.
PMID: 26722306
Oncol Lett. 2015 Nov;10(5):3163-3170. doi: 10.3892/ol.2015.3660. Epub 2015 Sep 02.

The present study aimed to evaluate any changes in the plasma concentrations of adrenomedullin (ADM), atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in patients with adrenal pheochromocytoma (PC). The plasma concentrations of the three peptides were measured...

β2-adrenergic stress evaluation of coronary endothelial-dependent vasodilator function in mice using (11)C-acetate micro-PET imaging of myocardial blood flow and oxidative metabolism.

EJNMMI research

Croteau E, Renaud JM, Archer C, Klein R, DaSilva JN, Ruddy TD, Beanlands RS, deKemp RA.
PMID: 25621195
EJNMMI Res. 2014 Dec 16;4(1):68. doi: 10.1186/s13550-014-0068-9. eCollection 2014 Dec.

BACKGROUND: Endothelial dysfunction is associated with vascular risk factors such as dyslipidemia, hypertension, and diabetes, leading to coronary atherosclerosis. Sympathetic stress using cold-pressor testing (CPT) has been used to measure coronary endothelial function in humans with positron emission tomography...

Evaluation of anxiolytic potency of essential oil and S-(+)-linalool from Cinnamomum osmophloeum ct. linalool leaves in mice.

Journal of traditional and complementary medicine

Cheng BH, Sheen LY, Chang ST.
PMID: 26151006
J Tradit Complement Med. 2014 Dec 16;5(1):27-34. doi: 10.1016/j.jtcme.2014.10.007. eCollection 2015 Jan.

Cinnamomum osmophloeum ct. linalool ( tǔ ròu guì) is one chemotype of the indigenous cinnamons in Taiwan. This study examined the anxiolytic potency of leaf essential oil (LEO) from C. osmophloeum ct. linalool and its main constituent on 4-week...

The inhibitory avoidance discrimination task to investigate accuracy of memory.

Frontiers in behavioral neuroscience

Atucha E, Roozendaal B.
PMID: 25814942
Front Behav Neurosci. 2015 Mar 12;9:60. doi: 10.3389/fnbeh.2015.00060. eCollection 2015.

The present study was aimed at developing a new inhibitory avoidance task, based on training and/or testing rats in multiple contexts, to investigate accuracy of memory. In the first experiment, male Sprague-Dawley rats were given footshock in an inhibitory...

A Case of Adrenergic Urticaria Associated with Vitiligo.

Dermatopathology (Basel, Switzerland)

Lang C, Kaya G.
PMID: 28232908
Dermatopathology (Basel). 2016 Dec 15;3(4):83-86. doi: 10.1159/000452302. eCollection 2016.

Adrenergic urticaria is a rare form of urticaria, induced by a stress-induced concomitant release of epinephrine and norepinephrine. Here we describe the case of a 60-year-old female patient presenting with disseminated erythematous papules surrounded by a white halo and...

Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response.

Molecular metabolism

Rojas JM, Matsen ME, Mundinger TO, Morton GJ, Stefanovski D, Bergman RN, Kaiyala KJ, Taborsky GJ, Schwartz MW.
PMID: 26266088
Mol Metab. 2015 Jun 04;4(8):561-8. doi: 10.1016/j.molmet.2015.05.005. eCollection 2015 Aug.

OBJECTIVE: Central administration of ligands for fibroblast growth factor receptors (FGFRs) such as fibroblast growth factor-19 (FGF19) and FGF21 exert glucose-lowering effects in rodent models of obesity and type 2 diabetes (T2D). Conversely, intracerebroventricular (icv) administration of the non-selective...

Pharmacological evidence of α-adrenergic receptors in the hypotensive effect of Chamaemulum nobile L.

Cardiovascular & hematological agents in medicinal chemistry

Hebi M, Ajebli M, Zeggwagh NA, Eddouks M.
PMID: 27052027
Cardiovasc Hematol Agents Med Chem. 2016 Apr 07; Epub 2016 Apr 07.

This study aims to evaluate the underlying mechanism of action involved in the hypotensive effect of Chamaemulum nobile L. (Cn) aqueous extract and in anesthetized Wistar rats. Lyophilized aqueous extract was administered in the jugular vein, arterial blood pressure...

Showing 13 to 24 of 2808 entries