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Showing 25 to 36 of 488 entries
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Activation of Polynuclear Aromatic Hydrocarbons to Mutagens by the Marine Ciliate Parauronema acutum.

Applied and environmental microbiology

Lindmark DG.
PMID: 16345775
Appl Environ Microbiol. 1981 May;41(5):1238-42. doi: 10.1128/aem.41.5.1238-1242.1981.

The marine ciliate Parauronema acutum converted 2-aminofluorene and 2-acetylaminofluorene to compounds with mutagenic activity in the Ames Salmonella test. The ciliate, however, did not activate benzo (alpha)pyrene or benzanthracene or destroy the mutagenic properties of nitrosoguanidine. Homogenates, when substituted...

Nucleophilic iron catalysis in transesterifications: scope and limitations.

The Journal of organic chemistry

Magens S, Plietker B.
PMID: 20462205
J Org Chem. 2010 Jun 04;75(11):3715-21. doi: 10.1021/jo1004636.

The ester bond is one of the most common structural motifs found in nature. Apart from the condensation between an acid and an alcohol, transesterifications represent another mechanistic alternative for the preparation of this compound class. The present paper...

Ames assay chromatograms and the identification of mutagens in diesel particle extracts.

Environmental science & technology

Salmeen IT, Pero AM, Zator R, Schuetzle D, Riley TL.
PMID: 22280088
Environ Sci Technol. 1984 May 01;18(5):375-82. doi: 10.1021/es00123a017.

No abstract available.

Photochemical mutagen formation from aerobically treated night-soil effluent and the contributive substances.

Environmental pollution (Barking, Essex : 1987)

Suzuki J, Muroga H, Suzuki S.
PMID: 15092599
Environ Pollut. 1988;52(4):257-64. doi: 10.1016/0269-7491(88)90128-5.

Effluents from a night-soil treatment plant, where night-soil was aerobically treated by an activated sludge process, were irradiated with a UV lamp excluding short wavelengths less than 300 nm as a model of exposure to sunlight and the mutagenicities...

Interaction between chemical mutagens with a delayed effect and metabolites of seeds : Communication I: The cytogenetic action of mutagens as related to the physiological condition of seeds.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Protopopova EM, Shevchenko VV, Grigoriyeva GA.
PMID: 24429909
Theor Appl Genet. 1971 Jan;41(1):21-4. doi: 10.1007/BF00279294.

A study was made of the cytogenetic effect of mutagens with a delayed effect (ethylenimine and ethyl methanesulphonate) on Crepis capillaris seeds. The effect was found to depend on the physiological condition of the seeds. In seeds not subjected...

Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancer.

Journal of biomedical research

Wang M, Chu H, Zhang Z, Wei Q.
PMID: 23720673
J Biomed Res. 2013 May;27(3):179-92. doi: 10.7555/JBR.27.20130034. Epub 2013 Apr 16.

Although tobacco and alcohol consumption are two common risk factors of head and neck cancer (HNC), other specific etiologic causes, such as viral infection and genetic susceptibility factors, remain to be understood. Human DNA is often damaged by numerous...

Current status of prostate-cancer research - development of in-vitro model systems (review).

International journal of oncology

Chah J, Rhim J.
PMID: 21559703
Int J Oncol. 1994 Dec;5(6):1233-42. doi: 10.3892/ijo.5.6.1233.

Prostate cancer is a major medical problem which is expected to affect over 200,000 US men in 1994. Despite its widespread prevalence and the difficulties in clinical diagnosis and treatment of the disease, the contribution of environmental factors and...

Should autism be considered a canary bird telling that Homo sapiens may be on its way to extinction?.

Microbial ecology in health and disease

Christophersen OA.
PMID: 23990819
Microb Ecol Health Dis. 2012 Aug 24;23. doi: 10.3402/mehd.v23i0.19008. eCollection 2012.

There has been a dramatic enhancement of the reported incidence of autism in different parts of the world over the last 30 years. This can apparently not be explained only as a result of improved diagnosis and reporting, but...

An evolutionary perspective on anti-tumor immunity.

Frontiers in oncology

Klinke DJ.
PMID: 23336100
Front Oncol. 2013 Jan 10;2:202. doi: 10.3389/fonc.2012.00202. eCollection 2012.

The challenges associated with demonstrating a durable response using molecular-targeted therapies in cancer has sparked a renewed interest in viewing cancer from an evolutionary perspective. Evolutionary processes have three common traits: heterogeneity, dynamics, and a selective fitness landscape. Mutagens...

The mTOR Pathway and the Role of Energy Balance Throughout Life in Colorectal Cancer Etiology and Prognosis: Unravelling Mechanisms Through a Multidimensional Molecular Epidemiologic Approach.

Current nutrition reports

Weijenberg MP, Hughes LA, Bours MJ, Simons CC, van Engeland M, van den Brandt PA.
PMID: 23396869
Curr Nutr Rep. 2013 Mar;2(1):19-26. doi: 10.1007/s13668-012-0038-7. Epub 2013 Jan 08.

Timing of exposure to lifestyle factors that influence energy balance may differentially affect colorectal cancer (CRC) risk and prognosis. Caloric restriction in youth and short stature, as markers of early-life exposures, have shown to decrease CRC risk, whereas large...

Current Status of Short-Term Tests for Evaluation of Genotoxicity, Mutagenicity, and Carcinogenicity of Environmental Chemicals and NCEs.

Toxicology mechanisms and methods

Bajpayee M, Pandey AK, Parmar D, Dhawan A.
PMID: 20021080
Toxicol Mech Methods. 2005;15(3):155-80. doi: 10.1080/15376520590945667.

The advent of the industrial revolution has seen a significant increase in the number of new chemical entities (NCEs) released in the environment. It becomes imperative to check the toxic potential of NCEs to nontarget species before they are...

The Salmonella mutagenicity of water and sediments from the Porsuk River in Turkey.

Environmental toxicology and pharmacology

Kutlu M, Aydoğan G, Susuz F, Ozata A.
PMID: 21782721
Environ Toxicol Pharmacol. 2004 Jun;17(2):111-6. doi: 10.1016/j.etap.2004.03.005.

In this study, water and sediments from the Porsuk River were investigated for their potential mutagenicity in Salmonella typhimurium TA 98 and TA 100 strains by performing Ames test (plate incorporation assay) without metabolic activation. Different columns of XAD...

Showing 25 to 36 of 488 entries