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Expression of Microtubule-Associated Proteins in Relation to Prognosis and Efficacy of Immunotherapy in Non-Small Cell Lung Cancer.

Frontiers in oncology

Luo J, Hu Q, Gou M, Liu X, Qin Y, Zhu J, Cai C, Tian T, Tu Z, Du Y, Deng H.
PMID: 34660263
Front Oncol. 2021 Oct 01;11:680402. doi: 10.3389/fonc.2021.680402. eCollection 2021.

BACKGROUND: Microtubule-associated proteins (MAPs) have been considered to play significant roles in the tumor evolution of non-small cell lung cancer (NSCLC). Nevertheless, mRNA transcription levels and prognostic value of distinct MAPs in patients with NSCLC remain to be clarified.METHODS:...

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Luo J, Hu Q, Gou M, et al. Expression of Microtubule-Associated Proteins in Relation to Prognosis and Efficacy of Immunotherapy in Non-Small Cell Lung Cancer. Front Oncol. 2021;11:680402doi: 10.3389/fonc.2021.680402.
Luo, J., Hu, Q., Gou, M., Liu, X., Qin, Y., Zhu, J., Cai, C., Tian, T., Tu, Z., Du, Y., & Deng, H. (2021). Expression of Microtubule-Associated Proteins in Relation to Prognosis and Efficacy of Immunotherapy in Non-Small Cell Lung Cancer. Frontiers in oncology, 11680402. https://doi.org/10.3389/fonc.2021.680402
Luo, Jieyan, et al. "Expression of Microtubule-Associated Proteins in Relation to Prognosis and Efficacy of Immunotherapy in Non-Small Cell Lung Cancer." Frontiers in oncology vol. 11 (2021): 680402. doi: https://doi.org/10.3389/fonc.2021.680402
Luo J, Hu Q, Gou M, Liu X, Qin Y, Zhu J, Cai C, Tian T, Tu Z, Du Y, Deng H. Expression of Microtubule-Associated Proteins in Relation to Prognosis and Efficacy of Immunotherapy in Non-Small Cell Lung Cancer. Front Oncol. 2021 Oct 01;11:680402. doi: 10.3389/fonc.2021.680402. eCollection 2021. PMID: 34660263; PMCID: PMC8517487.
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XB130 plays an essential role in folliculogenesis through mediating interactions between microfilament and microtubule systems in thyrocytes.

Thyroid : official journal of the American Thyroid Association

Wang Y, Xiang YY, Sugihara J, Lu WY, Liao XH, Arvan P, Refetoff S, Liu M.
PMID: 34652970
Thyroid. 2021 Oct 15; doi: 10.1089/thy.2021.0461. Epub 2021 Oct 15.

BACKGROUND: XB130 (actin filament associated protein 1 like 2, AFAP1L2) is a thyroid-abundant adaptor/scaffold protein. Xb130-/- mice exhibit transient growth retardation postnatally due to congenital hypothyroidism with diminished thyroglobulin iodination and release at both embryonic and early postnatal stages,...

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Wang Y, Xiang YY, Sugihara J, et al. XB130 plays an essential role in folliculogenesis through mediating interactions between microfilament and microtubule systems in thyrocytes. Thyroid. 2021;doi: 10.1089/thy.2021.0461.
Wang, Y., Xiang, Y. Y., Sugihara, J., Lu, W. Y., Liao, X. H., Arvan, P., Refetoff, S., & Liu, M. (2021). XB130 plays an essential role in folliculogenesis through mediating interactions between microfilament and microtubule systems in thyrocytes. Thyroid : official journal of the American Thyroid Association, . https://doi.org/10.1089/thy.2021.0461
Wang, Yingchun, et al. "XB130 plays an essential role in folliculogenesis through mediating interactions between microfilament and microtubule systems in thyrocytes." Thyroid : official journal of the American Thyroid Association vol. (2021). doi: https://doi.org/10.1089/thy.2021.0461
Wang Y, Xiang YY, Sugihara J, Lu WY, Liao XH, Arvan P, Refetoff S, Liu M. XB130 plays an essential role in folliculogenesis through mediating interactions between microfilament and microtubule systems in thyrocytes. Thyroid. 2021 Oct 15; doi: 10.1089/thy.2021.0461. Epub 2021 Oct 15. PMID: 34652970.
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Spatial regulation of microtubule-dependent transport by septin GTPases.

Trends in cell biology

Spiliotis ET, Kesisova IA.
PMID: 34253430
Trends Cell Biol. 2021 Dec;31(12):979-993. doi: 10.1016/j.tcb.2021.06.004. Epub 2021 Jul 09.

The intracellular long-range transport of membrane vesicles and organelles is mediated by microtubule motors (kinesins, dynein) which move cargo with spatiotemporal accuracy and efficiency. How motors navigate the microtubule network and coordinate their activity on membrane cargo are fundamental...

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Spiliotis ET, Kesisova IA. Spatial regulation of microtubule-dependent transport by septin GTPases. Trends Cell Biol. 2021;31(12):979-993doi: 10.1016/j.tcb.2021.06.004.
Spiliotis, E. T., & Kesisova, I. A. (2021). Spatial regulation of microtubule-dependent transport by septin GTPases. Trends in cell biology, 31(12), 979-993. https://doi.org/10.1016/j.tcb.2021.06.004
Spiliotis, Elias T, and Kesisova, Ilona A. "Spatial regulation of microtubule-dependent transport by septin GTPases." Trends in cell biology vol. 31,12 (2021): 979-993. doi: https://doi.org/10.1016/j.tcb.2021.06.004
Spiliotis ET, Kesisova IA. Spatial regulation of microtubule-dependent transport by septin GTPases. Trends Cell Biol. 2021 Dec;31(12):979-993. doi: 10.1016/j.tcb.2021.06.004. Epub 2021 Jul 09. PMID: 34253430; PMCID: PMC8595587.
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Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasis.

Journal of extracellular vesicles

Van den Broek B, Pintelon I, Hamad I, Kessels S, Haidar M, Hellings N, Hendriks JJA, Kleinewietfeld M, Brône B, Timmerman V, Timmermans JP, Somers V, Michiels L, Irobi J.
PMID: 33708355
J Extracell Vesicles. 2020 Nov;10(1):e12022. doi: 10.1002/jev2.12022. Epub 2020 Nov 25.

Microglia, the immunocompetent cells of the central nervous system (CNS), play an important role in maintaining cellular homeostasis in the CNS. These cells secrete immunomodulatory factors including nanovesicles and participate in the removal of cellular debris by phagocytosis or...

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Van den Broek B, Pintelon I, Hamad I, et al. Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasis. J Extracell Vesicles. 2020;10(1):e12022doi: 10.1002/jev2.12022.
Van den Broek, B., Pintelon, I., Hamad, I., Kessels, S., Haidar, M., Hellings, N., Hendriks, J. J. A., Kleinewietfeld, M., Brône, B., Timmerman, V., Timmermans, J. P., Somers, V., Michiels, L., & Irobi, J. (2020). Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasis. Journal of extracellular vesicles, 10(1), e12022. https://doi.org/10.1002/jev2.12022
Van den Broek, Bram, et al. "Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasis." Journal of extracellular vesicles vol. 10,1 (2020): e12022. doi: https://doi.org/10.1002/jev2.12022
Van den Broek B, Pintelon I, Hamad I, Kessels S, Haidar M, Hellings N, Hendriks JJA, Kleinewietfeld M, Brône B, Timmerman V, Timmermans JP, Somers V, Michiels L, Irobi J. Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasis. J Extracell Vesicles. 2020 Nov;10(1):e12022. doi: 10.1002/jev2.12022. Epub 2020 Nov 25. PMID: 33708355; PMCID: PMC7890546.
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Microtubule associated proteins as targets for anticancer drug development.

Bioorganic chemistry

Khwaja S, Kumar K, Das R, Negi AS.
PMID: 34492559
Bioorg Chem. 2021 Nov;116:105320. doi: 10.1016/j.bioorg.2021.105320. Epub 2021 Sep 01.

The dynamic equilibrium of tubulin-microtubule is an essential aspect of cell survivality. Modulation of this dynamics has become an important target for the cancer drug development. Tubulin exists in the alpha-beta dimer form which polymerizes to form microtubule and...

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Khwaja S, Kumar K, Das R, et al. Microtubule associated proteins as targets for anticancer drug development. Bioorg Chem. 2021;116:105320doi: 10.1016/j.bioorg.2021.105320.
Khwaja, S., Kumar, K., Das, R., & Negi, A. S. (2021). Microtubule associated proteins as targets for anticancer drug development. Bioorganic chemistry, 116105320. https://doi.org/10.1016/j.bioorg.2021.105320
Khwaja, Sadiya, et al. "Microtubule associated proteins as targets for anticancer drug development." Bioorganic chemistry vol. 116 (2021): 105320. doi: https://doi.org/10.1016/j.bioorg.2021.105320
Khwaja S, Kumar K, Das R, Negi AS. Microtubule associated proteins as targets for anticancer drug development. Bioorg Chem. 2021 Nov;116:105320. doi: 10.1016/j.bioorg.2021.105320. Epub 2021 Sep 01. PMID: 34492559.
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Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced Neurotrauma.

Frontiers in behavioral neuroscience

Dickerson MR, Murphy SF, Urban MJ, White Z, VandeVord PJ.
PMID: 34955781
Front Behav Neurosci. 2021 Dec 10;15:787475. doi: 10.3389/fnbeh.2021.787475. eCollection 2021.

Long-term neuropsychiatric impairments have become a growing concern following blast-related traumatic brain injury (bTBI) in active military personnel and Veterans. Neuropsychiatric impairments such as anxiety and depression are common comorbidities that Veterans report months, even years following injury. To...

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Dickerson MR, Murphy SF, Urban MJ, et al. Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced Neurotrauma. Front Behav Neurosci. 2021;15:787475doi: 10.3389/fnbeh.2021.787475.
Dickerson, M. R., Murphy, S. F., Urban, M. J., White, Z., & VandeVord, P. J. (2021). Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced Neurotrauma. Frontiers in behavioral neuroscience, 15787475. https://doi.org/10.3389/fnbeh.2021.787475
Dickerson, Michelle R, et al. "Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced Neurotrauma." Frontiers in behavioral neuroscience vol. 15 (2021): 787475. doi: https://doi.org/10.3389/fnbeh.2021.787475
Dickerson MR, Murphy SF, Urban MJ, White Z, VandeVord PJ. Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced Neurotrauma. Front Behav Neurosci. 2021 Dec 10;15:787475. doi: 10.3389/fnbeh.2021.787475. eCollection 2021. PMID: 34955781; PMCID: PMC8703020.
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Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Stathas S, Alvarez VE, Xia W, Nicks R, Meng G, Daley S, Pothast M, Shah A, Kelley H, Esnault C, McCormack R, Dixon E, Fishbein L, Cherry JD, Huber BR, Tripodis Y, Alosco ML, Mez J, McKee AC, Stein TD.
PMID: 34854540
Alzheimers Dement. 2021 Dec 02; doi: 10.1002/alz.12502. Epub 2021 Dec 02.

INTRODUCTION: Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive head impacts (RHI) typically sustained by contact sport athletes. Post-translation modifications to tau in CTE have not been well delineated or compared to Alzheimer's disease (AD).METHODS: We...

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Stathas S, Alvarez VE, Xia W, et al. Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease. Alzheimers Dement. 2021;doi: 10.1002/alz.12502.
Stathas, S., Alvarez, V. E., Xia, W., Nicks, R., Meng, G., Daley, S., Pothast, M., Shah, A., Kelley, H., Esnault, C., McCormack, R., Dixon, E., Fishbein, L., Cherry, J. D., Huber, B. R., Tripodis, Y., Alosco, M. L., Mez, J., McKee, A. C., & Stein, T. D. (2021). Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association, . https://doi.org/10.1002/alz.12502
Stathas, SpiroAnthony, et al. "Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. (2021). doi: https://doi.org/10.1002/alz.12502
Stathas S, Alvarez VE, Xia W, Nicks R, Meng G, Daley S, Pothast M, Shah A, Kelley H, Esnault C, McCormack R, Dixon E, Fishbein L, Cherry JD, Huber BR, Tripodis Y, Alosco ML, Mez J, McKee AC, Stein TD. Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease. Alzheimers Dement. 2021 Dec 02; doi: 10.1002/alz.12502. Epub 2021 Dec 02. PMID: 34854540.
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Showing 145 to 151 of 151 entries