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Showing 9985 to 9996 of 13722 entries
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Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms.

Biomedicines

Lin YC, Chen TH, Huang YM, Wei PL, Lin JC.
PMID: 33805515
Biomedicines. 2021 Mar 29;9(4). doi: 10.3390/biomedicines9040343.

MicroRNAs (miRNAs) function as the post-transcriptional factor that finetunes the gene expression by targeting to the specific candidate. Mis-regulated expression of miRNAs consequently disturbs gene expression profile, which serves as the pivotal mechanism involved in initiation or progression of...

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Lin YC, Chen TH, Huang YM, et al. Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms. Biomedicines. 2021;9(4)doi: 10.3390/biomedicines9040343.
Lin, Y. C., Chen, T. H., Huang, Y. M., Wei, P. L., & Lin, J. C. (2021). Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms. Biomedicines, 9(4), . https://doi.org/10.3390/biomedicines9040343
Lin, Ying-Chin, et al. "Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms." Biomedicines vol. 9,4 (2021). doi: https://doi.org/10.3390/biomedicines9040343
Lin YC, Chen TH, Huang YM, Wei PL, Lin JC. Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms. Biomedicines. 2021 Mar 29;9(4). doi: 10.3390/biomedicines9040343. PMID: 33805515; PMCID: PMC8065716.
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Clusterin and Its Potential Regulatory microRNAs as a Part of Secretome for the Diagnosis of Abnormally Invasive Placenta: Accreta, Increta, and Percreta Cases.

Life (Basel, Switzerland)

Timofeeva AV, Fedorov IS, Pirogova MM, Vasilchenko ON, Chagovets VV, Ezhova LS, Zabelina TM, Shmakov RG, Sukhikh GT.
PMID: 33805203
Life (Basel). 2021 Mar 24;11(4). doi: 10.3390/life11040270.

Magnetic resonance imaging (MRI) and ultrasound methods used for the diagnosis of an abnormally invasive placenta (AIP) have a wide range of sensitivity (Se, 33-93%) and specificity (Sp, 71-100%) levels, which results in a high risk of unfavorable maternal...

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Timofeeva AV, Fedorov IS, Pirogova MM, et al. Clusterin and Its Potential Regulatory microRNAs as a Part of Secretome for the Diagnosis of Abnormally Invasive Placenta: Accreta, Increta, and Percreta Cases. Life (Basel). 2021;11(4)doi: 10.3390/life11040270.
Timofeeva, A. V., Fedorov, I. S., Pirogova, M. M., Vasilchenko, O. N., Chagovets, V. V., Ezhova, L. S., Zabelina, T. M., Shmakov, R. G., & Sukhikh, G. T. (2021). Clusterin and Its Potential Regulatory microRNAs as a Part of Secretome for the Diagnosis of Abnormally Invasive Placenta: Accreta, Increta, and Percreta Cases. Life (Basel, Switzerland), 11(4), . https://doi.org/10.3390/life11040270
Timofeeva, Angelika V, et al. "Clusterin and Its Potential Regulatory microRNAs as a Part of Secretome for the Diagnosis of Abnormally Invasive Placenta: Accreta, Increta, and Percreta Cases." Life (Basel, Switzerland) vol. 11,4 (2021). doi: https://doi.org/10.3390/life11040270
Timofeeva AV, Fedorov IS, Pirogova MM, Vasilchenko ON, Chagovets VV, Ezhova LS, Zabelina TM, Shmakov RG, Sukhikh GT. Clusterin and Its Potential Regulatory microRNAs as a Part of Secretome for the Diagnosis of Abnormally Invasive Placenta: Accreta, Increta, and Percreta Cases. Life (Basel). 2021 Mar 24;11(4). doi: 10.3390/life11040270. PMID: 33805203; PMCID: PMC8064394.
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Non-coding RNAs in Cardiac Regeneration.

Frontiers in physiology

Yuan T, Krishnan J.
PMID: 33841185
Front Physiol. 2021 Mar 24;12:650566. doi: 10.3389/fphys.2021.650566. eCollection 2021.

The adult heart has a limited capacity to replace or regenerate damaged cardiac tissue following severe myocardial injury. Thus, therapies facilitating the induction of cardiac regeneration holds great promise for the treatment of end-stage heart failure, and for pathologies...

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Yuan T, Krishnan J. Non-coding RNAs in Cardiac Regeneration. Front Physiol. 2021;12:650566doi: 10.3389/fphys.2021.650566.
Yuan, T., & Krishnan, J. (2021). Non-coding RNAs in Cardiac Regeneration. Frontiers in physiology, 12650566. https://doi.org/10.3389/fphys.2021.650566
Yuan, Ting, and Krishnan, Jaya. "Non-coding RNAs in Cardiac Regeneration." Frontiers in physiology vol. 12 (2021): 650566. doi: https://doi.org/10.3389/fphys.2021.650566
Yuan T, Krishnan J. Non-coding RNAs in Cardiac Regeneration. Front Physiol. 2021 Mar 24;12:650566. doi: 10.3389/fphys.2021.650566. eCollection 2021. PMID: 33841185; PMCID: PMC8024481.
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Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia.

Oncology letters

Lin XC, Yang Q, Fu WY, Lan LB, Ding H, Zhang YM, Li N, Zhang HT.
PMID: 33281961
Oncol Lett. 2021 Jan;21(1):50. doi: 10.3892/ol.2020.12311. Epub 2020 Nov 18.

Acutemonocytic leukemia (AMoL) is a distinct subtype of acute myeloid leukemia (AML) with poor prognosis. However, the molecular mechanisms and key regulators involved in the global regulation of gene expression levels in AMoL are poorly understood. In order to...

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Lin XC, Yang Q, Fu WY, et al. Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia. Oncol Lett. 2020;21(1):50doi: 10.3892/ol.2020.12311.
Lin, X. C., Yang, Q., Fu, W. Y., Lan, L. B., Ding, H., Zhang, Y. M., Li, N., & Zhang, H. T. (2021). Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia. Oncology letters, 21(1), 50. https://doi.org/10.3892/ol.2020.12311
Lin, Xiao-Cong, et al. "Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia." Oncology letters vol. 21,1 (2021): 50. doi: https://doi.org/10.3892/ol.2020.12311
Lin XC, Yang Q, Fu WY, Lan LB, Ding H, Zhang YM, Li N, Zhang HT. Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia. Oncol Lett. 2021 Jan;21(1):50. doi: 10.3892/ol.2020.12311. Epub 2020 Nov 18. PMID: 33281961; PMCID: PMC7709554.
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Cpeb1 expression is post-transcriptionally regulated by AUF1, CPEB1, and microRNAs.

FEBS open bio

Oe S, Hayashi S, Tanaka S, Koike T, Hirahara Y, Kakizaki R, Sakamoto S, Noda Y, Yamada H, Kitada M.
PMID: 34480525
FEBS Open Bio. 2021 Sep 04; doi: 10.1002/2211-5463.13286. Epub 2021 Sep 04.

Cytoplasmic polyadenylation element binding protein 1 (CPEB1) regulates the translation of numerous mRNAs. We previously showed that AU-rich binding factor 1 (AUF1) regulates Cpeb1 expression through the 3' untranslated region (3'UTR). To investigate the molecular basis of the regulatory...

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Oe S, Hayashi S, Tanaka S, et al. Cpeb1 expression is post-transcriptionally regulated by AUF1, CPEB1, and microRNAs. FEBS Open Bio. 2021;doi: 10.1002/2211-5463.13286.
Oe, S., Hayashi, S., Tanaka, S., Koike, T., Hirahara, Y., Kakizaki, R., Sakamoto, S., Noda, Y., Yamada, H., & Kitada, M. (2021). Cpeb1 expression is post-transcriptionally regulated by AUF1, CPEB1, and microRNAs. FEBS open bio, . https://doi.org/10.1002/2211-5463.13286
Oe, Souichi, et al. "Cpeb1 expression is post-transcriptionally regulated by AUF1, CPEB1, and microRNAs." FEBS open bio vol. (2021). doi: https://doi.org/10.1002/2211-5463.13286
Oe S, Hayashi S, Tanaka S, Koike T, Hirahara Y, Kakizaki R, Sakamoto S, Noda Y, Yamada H, Kitada M. Cpeb1 expression is post-transcriptionally regulated by AUF1, CPEB1, and microRNAs. FEBS Open Bio. 2021 Sep 04; doi: 10.1002/2211-5463.13286. Epub 2021 Sep 04. PMID: 34480525.
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Serum Exosomal Circular RNA Expression Profile and Regulative Role in Proliferative Diabetic Retinopathy.

Frontiers in genetics

Li X, Wang J, Qian H, Wu Y, Zhang Z, Hu Z, Xie P.
PMID: 34447414
Front Genet. 2021 Aug 10;12:719312. doi: 10.3389/fgene.2021.719312. eCollection 2021.

BACKGROUND: Proliferative diabetic retinopathy (PDR), as one of the main microvascular complications of diabetes mellitus, seriously threatens the visual function of the working-age population; yet, the underlying pathogenesis is still poorly understood. This study aimed to identify the distinct...

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Li X, Wang J, Qian H, et al. Serum Exosomal Circular RNA Expression Profile and Regulative Role in Proliferative Diabetic Retinopathy. Front Genet. 2021;12:719312doi: 10.3389/fgene.2021.719312.
Li, X., Wang, J., Qian, H., Wu, Y., Zhang, Z., Hu, Z., & Xie, P. (2021). Serum Exosomal Circular RNA Expression Profile and Regulative Role in Proliferative Diabetic Retinopathy. Frontiers in genetics, 12719312. https://doi.org/10.3389/fgene.2021.719312
Li, Xinsheng, et al. "Serum Exosomal Circular RNA Expression Profile and Regulative Role in Proliferative Diabetic Retinopathy." Frontiers in genetics vol. 12 (2021): 719312. doi: https://doi.org/10.3389/fgene.2021.719312
Li X, Wang J, Qian H, Wu Y, Zhang Z, Hu Z, Xie P. Serum Exosomal Circular RNA Expression Profile and Regulative Role in Proliferative Diabetic Retinopathy. Front Genet. 2021 Aug 10;12:719312. doi: 10.3389/fgene.2021.719312. eCollection 2021. PMID: 34447414; PMCID: PMC8383346.
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A copper-free and enzyme-free click chemistry-mediated single quantum dot nanosensor for accurate detection of microRNAs in cancer cells and tissues.

Chemical science

Wang ZY, Li DL, Tian X, Zhang CY.
PMID: 34447534
Chem Sci. 2021 Jul 06;12(31):10426-10435. doi: 10.1039/d1sc01865e. eCollection 2021 Aug 11.

MicroRNAs (miRNAs) play key roles in the post-transcriptional regulation of genes, and their aberrant expression may disturb the normal gene regulation network to induce various diseases, and thus accurate detection of miRNAs is essential to early clinical diagnosis. Herein,...

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Wang ZY, Li DL, Tian X, et al. A copper-free and enzyme-free click chemistry-mediated single quantum dot nanosensor for accurate detection of microRNAs in cancer cells and tissues. Chem Sci. 2021;12(31):10426-10435doi: 10.1039/d1sc01865e.
Wang, Z. Y., Li, D. L., Tian, X., & Zhang, C. Y. (2021). A copper-free and enzyme-free click chemistry-mediated single quantum dot nanosensor for accurate detection of microRNAs in cancer cells and tissues. Chemical science, 12(31), 10426-10435. https://doi.org/10.1039/d1sc01865e
Wang, Zi-Yue, et al. "A copper-free and enzyme-free click chemistry-mediated single quantum dot nanosensor for accurate detection of microRNAs in cancer cells and tissues." Chemical science vol. 12,31 (2021): 10426-10435. doi: https://doi.org/10.1039/d1sc01865e
Wang ZY, Li DL, Tian X, Zhang CY. A copper-free and enzyme-free click chemistry-mediated single quantum dot nanosensor for accurate detection of microRNAs in cancer cells and tissues. Chem Sci. 2021 Jul 06;12(31):10426-10435. doi: 10.1039/d1sc01865e. eCollection 2021 Aug 11. PMID: 34447534; PMCID: PMC8356811.
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Strategies targeting FLT3 beyond the kinase inhibitors.

Pharmacology & therapeutics

Almatani MF, Ali A, Onyemaechi S, Zhao Y, Gutierrez L, Vaikari VP, Alachkar H.
PMID: 33811956
Pharmacol Ther. 2021 Sep;225:107844. doi: 10.1016/j.pharmthera.2021.107844. Epub 2021 Mar 31.

Acute myeloid leukemia (AML) is a hematological malignancy characterized by clonal expansion and differentiation arrest of the myeloid progenitor cells, which leads to the accumulation of immature cells called blasts in the bone marrow and peripheral blood. Mutations in...

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Almatani MF, Ali A, Onyemaechi S, et al. Strategies targeting FLT3 beyond the kinase inhibitors. Pharmacol Ther. 2021;225:107844doi: 10.1016/j.pharmthera.2021.107844.
Almatani, M. F., Ali, A., Onyemaechi, S., Zhao, Y., Gutierrez, L., Vaikari, V. P., & Alachkar, H. (2021). Strategies targeting FLT3 beyond the kinase inhibitors. Pharmacology & therapeutics, 225107844. https://doi.org/10.1016/j.pharmthera.2021.107844
Almatani, Mohammed F, et al. "Strategies targeting FLT3 beyond the kinase inhibitors." Pharmacology & therapeutics vol. 225 (2021): 107844. doi: https://doi.org/10.1016/j.pharmthera.2021.107844
Almatani MF, Ali A, Onyemaechi S, Zhao Y, Gutierrez L, Vaikari VP, Alachkar H. Strategies targeting FLT3 beyond the kinase inhibitors. Pharmacol Ther. 2021 Sep;225:107844. doi: 10.1016/j.pharmthera.2021.107844. Epub 2021 Mar 31. PMID: 33811956.
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miR-155-5p predictive role to decelerate foam cell atherosclerosis through CD36, VAV3, and SOCS1 pathway.

Non-coding RNA research

Rachmawati E, Sargowo D, Rohman MS, Widodo N, Kalsum U.
PMID: 33869908
Noncoding RNA Res. 2021 Mar 08;6(2):59-69. doi: 10.1016/j.ncrna.2021.02.003. eCollection 2021 Jun.

MicroRNAs (miRNAs) are noncoding RNA molecules that play a significant role in atherosclerosis pathogenesis through post-transcriptional regulation. In the present work, a bioinformatic analysis using TargetScan and miRdB databases was performed to identify the miRNAs targeting three genes involved...

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Rachmawati E, Sargowo D, Rohman MS, et al. miR-155-5p predictive role to decelerate foam cell atherosclerosis through CD36, VAV3, and SOCS1 pathway. Noncoding RNA Res. 2021;6(2):59-69doi: 10.1016/j.ncrna.2021.02.003.
Rachmawati, E., Sargowo, D., Rohman, M. S., Widodo, N., & Kalsum, U. (2021). miR-155-5p predictive role to decelerate foam cell atherosclerosis through CD36, VAV3, and SOCS1 pathway. Non-coding RNA research, 6(2), 59-69. https://doi.org/10.1016/j.ncrna.2021.02.003
Rachmawati, Ermin, et al. "miR-155-5p predictive role to decelerate foam cell atherosclerosis through CD36, VAV3, and SOCS1 pathway." Non-coding RNA research vol. 6,2 (2021): 59-69. doi: https://doi.org/10.1016/j.ncrna.2021.02.003
Rachmawati E, Sargowo D, Rohman MS, Widodo N, Kalsum U. miR-155-5p predictive role to decelerate foam cell atherosclerosis through CD36, VAV3, and SOCS1 pathway. Noncoding RNA Res. 2021 Mar 08;6(2):59-69. doi: 10.1016/j.ncrna.2021.02.003. eCollection 2021 Jun. PMID: 33869908; PMCID: PMC8027696.
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Targeting Wnt/β-catenin signaling by microRNAs as a therapeutic approach in chemoresistant osteosarcoma.

Biochemical pharmacology

Hosseini F, Alemi F, Malakoti F, Mahmoodpoor A, Younesi S, Yousefi B, Asemi Z.
PMID: 34481813
Biochem Pharmacol. 2021 Nov;193:114758. doi: 10.1016/j.bcp.2021.114758. Epub 2021 Sep 03.

Osteosarcoma (OS) is an adolescent and young adult malignancy that mostly occurs in long bones. The treatment of OS is still a big challenge for clinicians due to increasing chemoresistance, and many efforts are being made today to find...

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Hosseini F, Alemi F, Malakoti F, et al. Targeting Wnt/β-catenin signaling by microRNAs as a therapeutic approach in chemoresistant osteosarcoma. Biochem Pharmacol. 2021;193:114758doi: 10.1016/j.bcp.2021.114758.
Hosseini, F., Alemi, F., Malakoti, F., Mahmoodpoor, A., Younesi, S., Yousefi, B., & Asemi, Z. (2021). Targeting Wnt/β-catenin signaling by microRNAs as a therapeutic approach in chemoresistant osteosarcoma. Biochemical pharmacology, 193114758. https://doi.org/10.1016/j.bcp.2021.114758
Hosseini, Foroogh, et al. "Targeting Wnt/β-catenin signaling by microRNAs as a therapeutic approach in chemoresistant osteosarcoma." Biochemical pharmacology vol. 193 (2021): 114758. doi: https://doi.org/10.1016/j.bcp.2021.114758
Hosseini F, Alemi F, Malakoti F, Mahmoodpoor A, Younesi S, Yousefi B, Asemi Z. Targeting Wnt/β-catenin signaling by microRNAs as a therapeutic approach in chemoresistant osteosarcoma. Biochem Pharmacol. 2021 Nov;193:114758. doi: 10.1016/j.bcp.2021.114758. Epub 2021 Sep 03. PMID: 34481813.
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Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome.

Placenta

Beharier O, Kajiwara K, Sadovsky Y.
PMID: 33812183
Placenta. 2021 May;108:32-38. doi: 10.1016/j.placenta.2021.03.007. Epub 2021 Mar 16.

Programmed cell death is a central process in the control of tissue development, organismal physiology, and disease. Ferroptosis is a recently identified form of programmed cell death that is uniquely defined by redox-active iron-dependent hydroxy-peroxidation of polyunsaturated fatty acid...

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Beharier O, Kajiwara K, Sadovsky Y. Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome. Placenta. 2021;108:32-38doi: 10.1016/j.placenta.2021.03.007.
Beharier, O., Kajiwara, K., & Sadovsky, Y. (2021). Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome. Placenta, 10832-38. https://doi.org/10.1016/j.placenta.2021.03.007
Beharier, Ofer, et al. "Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome." Placenta vol. 108 (2021): 32-38. doi: https://doi.org/10.1016/j.placenta.2021.03.007
Beharier O, Kajiwara K, Sadovsky Y. Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome. Placenta. 2021 May;108:32-38. doi: 10.1016/j.placenta.2021.03.007. Epub 2021 Mar 16. PMID: 33812183; PMCID: PMC8127417.
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Mesenchymal stem cell-derived exosome microRNA as therapy for cardiac ischemic injury.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Nasser MI, Masood M, Adlat S, Gang D, Zhu S, Li G, Li N, Chen J, Zhu P.
PMID: 34481378
Biomed Pharmacother. 2021 Nov;143:112118. doi: 10.1016/j.biopha.2021.112118. Epub 2021 Sep 01.

Cardiovascular diseases (CVD) are a significant cause of human health harm. In the past, stem cell therapy was reported to have functional defects, such as immune rejection, tumorigenicity, and infusion toxicity. Exosomes are extracellular vesicles with lipid bilayer membrane...

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Nasser MI, Masood M, Adlat S, et al. Mesenchymal stem cell-derived exosome microRNA as therapy for cardiac ischemic injury. Biomed Pharmacother. 2021;143:112118doi: 10.1016/j.biopha.2021.112118.
Nasser, M. I., Masood, M., Adlat, S., Gang, D., Zhu, S., Li, G., Li, N., Chen, J., & Zhu, P. (2021). Mesenchymal stem cell-derived exosome microRNA as therapy for cardiac ischemic injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 143112118. https://doi.org/10.1016/j.biopha.2021.112118
Nasser, M I, et al. "Mesenchymal stem cell-derived exosome microRNA as therapy for cardiac ischemic injury." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 143 (2021): 112118. doi: https://doi.org/10.1016/j.biopha.2021.112118
Nasser MI, Masood M, Adlat S, Gang D, Zhu S, Li G, Li N, Chen J, Zhu P. Mesenchymal stem cell-derived exosome microRNA as therapy for cardiac ischemic injury. Biomed Pharmacother. 2021 Nov;143:112118. doi: 10.1016/j.biopha.2021.112118. Epub 2021 Sep 01. PMID: 34481378.
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Showing 9985 to 9996 of 13722 entries