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Showing 25 to 36 of 507 entries
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Assessment of Drug-Drug Interactions among Renal Failure Patients of Nephrology Ward in a South Indian Tertiary Care Hospital.

Indian journal of pharmaceutical sciences

Rama M, Viswanathan G, Acharya LD, Attur RP, Reddy PN, Raghavan SV.
PMID: 23204624
Indian J Pharm Sci. 2012 Jan;74(1):63-8. doi: 10.4103/0250-474X.102545.

Polypharmacy is common in drug prescriptions of chronic kidney disease patients. A study of the prescription patterns of drugs with potential interactions would be of interest to prevent drug related adverse events. A prospective observational study of six months...

Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats.

Experimental and clinical cardiology

Su Q, Li L, Liu YC, Zhou Y, Lu YG, Wen WM.
PMID: 23940444
Exp Clin Cardiol. 2013;18(2):161-5.

OBJECTIVE: To explore the effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization (CME) in rats.METHODS: Forty rats were randomly divided into four groups (n=10 each): a sham operation (control) group, CME plus saline (CME) group,...

Concomitant administration of simvastatin with ivabradine in contrast to metoprolol intensifies slowing of heart rate in normo- and hypercholesterolemic rats.

Archives of medical science : AMS

Owczarek J, Jasińska M, Drożdż J, Orszulak-Michalak D.
PMID: 22852014
Arch Med Sci. 2012 Jul 04;8(3):549-54. doi: 10.5114/aoms.2012.29411.

INTRODUCTION: β-Blockers play a significant role in therapeutic heart rate (HR) management and angina control. In patients who are unable to tolerate β-blockers ivabradine could be particularly useful. The aim of the study was to establish whether concomitant administration...

Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Zhou Y, Wang S, Ding T, Chen M, Wang L, Wu M, Hu G, Lu X.
PMID: 25464097
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Dec 15;973:68-75. doi: 10.1016/j.jchromb.2014.10.013. Epub 2014 Oct 22.

An accurate and validated liquid chromatography method and a triple quadrupole mass spectrometry method were developed and validated to simultaneously evaluate the cytochrome P450 (CYP) enzymes in vivo using the co-administration of these probes. Phenacetin, losartan, metoprolol and midazolam...

Chiral Recognition Mechanisms of four β-Blockers by HPLC with Amylose Chiral Stationary Phase.

Iranian journal of pharmaceutical research : IJPR

Wang D, Li F, Jiang Z, Yu L, Guo X.
PMID: 25237340
Iran J Pharm Res. 2014;13(2):449-57.

The high performance liquid chromatography (HPLC) enantioseparation of four β-blocking agents metoprolol, bisoprolol, propranolol and atenolol was performed on amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase using n-hexane-ethanol-diethylamine (DEA) as the mobile phase and related chiral recognition mechanisms were discussed. Enantiomeric...

Comparing the therapeutic effects of carvedilol and metoprolol on prevention of atrial fibrillation after coronary artery bypass surgery, a double-blind study.

International cardiovascular research journal

Jalalian R, Ghafari R, Ghazanfari P.
PMID: 25177674
Int Cardiovasc Res J. 2014 Sep;8(3):111-5. Epub 2014 Sep 01.

BACKGROUND: Atrial Fibrillation (AF) is a common complication after open heart surgery and is frequently associated with increased hospital stay, complications, and mortality rates. The effect of β-blockers on prevention of supraventricular arrhythmias has been confirmed in several prospective...

Development and Validation of HPTLC Method for Simultaneous Determination of Amlodipine Besylate and Metoprolol Succinate in Bulk and Tablets.

Indian journal of pharmaceutical sciences

Jain PS, Patel MK, Bari SB, Surana SJ.
PMID: 23325996
Indian J Pharm Sci. 2012 Mar;74(2):152-6. doi: 10.4103/0250-474X.103849.

A simple, selective, precise high-performance thin-layer chromatographic method for simultaneous determination of amlodipine besylate and metoprolol succinate in bulk and pharmaceutical combined dosage form was developed and validated. The method employed HPTLC aluminum plates precoated with silica gel 60F-254...

Potential drug interactions in patients with a history of cancer.

Current oncology (Toronto, Ont.)

Chen L, Cheung WY.
PMID: 24764706
Curr Oncol. 2014 Apr;21(2):e212-20. doi: 10.3747/co.21.1657.

BACKGROUND: Cancer survivors (css) are frequently exposed to polypharmacy, which might increase their risk of drug interactions. Our study aimed to determine the relative prevalence of potential drug interactions (pdis) among css compared with non-cancer respondents (ncrs).METHODS: Self-reported prescription...

Analysis of therapeutic effect and safety of target-dose metoprolol in the treatment of patients with diabetes mellitus with chronic heart failure.

Pakistan journal of medical sciences

Liu X, Zhong C, Zhao P, Zhang Z, Jia N, Su S, Zou B, Song Y.
PMID: 24639821
Pak J Med Sci. 2014 Jan;30(1):7-11. doi: 10.12669/pjms.301.3908.

OBJECTIVE: To explore the therapeutic effect and safety of target-dose metoprolol in treating chronic heart failure (CHF) patients complicated with diabetes mellitus (DM). Method s : One hundred and fifty-four elderly patients were randomly divided into an observation group...

A Series of 211 Children with Probable Essential Tremor.

Movement disorders clinical practice

Ghosh D, Brar H, Lhamu U, Rothner AD, Erenberg G.
PMID: 30363473
Mov Disord Clin Pract. 2016 Jul 08;4(2):231-236. doi: 10.1002/mdc3.12385. eCollection 2017.

BACKGROUND: The objective of this study was to characterize the clinical features, course, and treatment of essential tremor (ET) in children.METHODS: A retrospective chart review was conducted over 25 years (1984-2011). Inclusion criteria were age

Nebivolol Attenuates Neutrophil Lymphocyte Ratio: A Marker of Subclinical Inflammation in Hypertensive Patients.

International journal of hypertension

Hussain M, Saeed M, Babar MZM, Atif MA, Akhtar L.
PMID: 28819568
Int J Hypertens. 2017;2017:7643628. doi: 10.1155/2017/7643628. Epub 2017 Jul 27.

BACKGROUND: High value of neutrophil lymphocyte ratio (NLR) is a strong independent predictor and biomarker of ongoing vascular inflammation in various cardiovascular disorders.OBJECTIVE: The main focus of the study is to investigate the effect of nebivolol on NLR in...

Acute Myocardial Injury in a Child with Duchenne Muscular Dystrophy: Pulse Steroid Therapy?.

Maedica

Cinteza E, Stoicescu C, Butoianu N, Balgradean M, Nicolescu A, Angrés M.
PMID: 29218065
Maedica (Bucur). 2017 Sep;12(3):180-183.

Heart implication in Duchenne muscular dystrophy usually is present in the form of dilated cardiomyopathy, manifested as heart failure and arrhythmias. To delay progression, including heart deterioration, prednisone is recommended as preventive treatment. We report the case of an...

Showing 25 to 36 of 507 entries