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Showing 25 to 36 of 52 entries
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Regulation of blood-brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide.

Microbiome

Hoyles L, Pontifex MG, Rodriguez-Ramiro I, Anis-Alavi MA, Jelane KS, Snelling T, Solito E, Fonseca S, Carvalho AL, Carding SR, Müller M, Glen RC, Vauzour D, McArthur S.
PMID: 34836554
Microbiome. 2021 Nov 27;9(1):235. doi: 10.1186/s40168-021-01181-z.

BACKGROUND: Communication between the gut microbiota and the brain is primarily mediated via soluble microbe-derived metabolites, but the details of this pathway remain poorly defined. Methylamines produced by microbial metabolism of dietary choline and L-carnitine have received attention due...

Large-scale protein level comparison of Deltaproteobacteria reveals cohesive metabolic groups.

The ISME journal

Langwig MV, De Anda V, Dombrowski N, Seitz KW, Rambo IM, Greening C, Teske AP, Baker BJ.
PMID: 34331018
ISME J. 2022 Jan;16(1):307-320. doi: 10.1038/s41396-021-01057-y. Epub 2021 Jul 30.

Deltaproteobacteria, now proposed to be the phyla Desulfobacterota, Myxococcota, and SAR324, are ubiquitous in marine environments and play essential roles in global carbon, sulfur, and nutrient cycling. Despite their importance, our understanding of these bacteria is biased towards cultured...

Large-scale protein level comparison of Deltaproteobacteria reveals cohesive metabolic groups.

The ISME journal

Langwig MV, De Anda V, Dombrowski N, Seitz KW, Rambo IM, Greening C, Teske AP, Baker BJ.
PMID: 34331018
ISME J. 2021 Jul 30; doi: 10.1038/s41396-021-01057-y. Epub 2021 Jul 30.

Deltaproteobacteria, now proposed to be the phyla Desulfobacterota, Myxococcota, and SAR324, are ubiquitous in marine environments and play essential roles in global carbon, sulfur, and nutrient cycling. Despite their importance, our understanding of these bacteria is biased towards cultured...

Understanding Fermi resonances in the complex vibrational spectra of the methyl groups in methylamines.

Physical chemistry chemical physics : PCCP

Huang QR, Endo T, Mishra S, Zhang B, Chen LW, Fujii A, Jiang L, Patwari GN, Matsuda Y, Kuo JL.
PMID: 33533768
Phys Chem Chem Phys. 2021 Feb 19;23(6):3739-3747. doi: 10.1039/d0cp05745b.

Vibrational spectra of the methyl groups in mono-methylamine (MMA), dimethylamine (DMA), and trimethylamine (TMA) monomers and their clusters were measured in three experimental set-ups to capture their complex spectral features as a result of bend/umbrella-stretch Fermi resonance (FR). Multiple...

Pyrrolysine in archaea: a 22nd amino acid encoded through a genetic code expansion.

Emerging topics in life sciences

Brugère JF, Atkins JF, O'Toole PW, Borrel G.
PMID: 33525836
Emerg Top Life Sci. 2018 Dec 14;2(4):607-618. doi: 10.1042/ETLS20180094.

The 22nd amino acid discovered to be directly encoded, pyrrolysine, is specified by UAG. Until recently, pyrrolysine was only known to be present in archaea from a methanogenic lineage (Methanosarcinales), where it is important in enzymes catalysing anoxic methylamines...

Asymmetric synthesis of (triaryl)methylamines by rhodium-catalyzed addition of arylboroxines to cyclic N-sulfonyl ketimines.

Journal of the American Chemical Society

Nishimura T, Noishiki A, Tsui GC, Hayashi T.
PMID: 22394013
J Am Chem Soc. 2012 Mar 21;134(11):5056-9. doi: 10.1021/ja300697c. Epub 2012 Mar 08.

Asymmetric addition of arylboroxines to cyclic N-sulfonyl ketimines proceeded in the presence of a rhodium catalyst coordinated with a chiral diene ligand to give high yields of benzosultams, where a triaryl-substituted stereogenic carbon center was created with high enantioselectivity...

A precoordination complex of 1,2,3-trimethyl-1,3,5-triazacyclohexane with tert-butyllithium as key intermediate in its methylene group deprotonation.

Chemistry, an Asian journal

Strohmann C, Gessner VH.
PMID: 18752226
Chem Asian J. 2008 Nov 13;3(11):1929-34. doi: 10.1002/asia.200800213.

Alpha-lithiated tertiary methylamines are important building blocks in all fields of chemistry, such as for the synthesis of new ligand or catalyst systems. However, the access to these compounds is still limited and the reaction mechanism, in general, not...

Ion-molecule reactions in mixtures of trimethylaluminum and methylamines.

Journal of the American Society for Mass Spectrometry

Bach SB, Parent DC.
PMID: 24234789
J Am Soc Mass Spectrom. 1993 Feb;4(2):111-6. doi: 10.1016/1044-0305(93)85066-7.

The ion-molecule reactions of mixtures of trimethylaluminum and methylamines, to serve as a model system for group 13-15 semiconductor fabrication, were examined by using Fourier transform ion cyclotron resonance mass spectrometry. Sequential ion-molecule reactions leading to formation of multiple...

Synthesis of N-methylated amines from acyl azides using methanol.

Organic & biomolecular chemistry

Chakrabarti K, Dutta K, Kundu S.
PMID: 32677635
Org Biomol Chem. 2020 Aug 05;18(30):5891-5896. doi: 10.1039/d0ob01303j.

The transformation of acyl azide derivatives into N-methylamines was developed using methanol as the C1 source via the one-pot Curtius rearrangement and borrowing hydrogen methodology. Following this protocol, various functionalised N-methylated amines were synthesized using the (NNN)Ru(ii) complex from...

Uncovering the Diversity and Activity of Methylotrophic Methanogens in Freshwater Wetland Soils.

mSystems

Narrowe AB, Borton MA, Hoyt DW, Smith GJ, Daly RA, Angle JC, Eder EK, Wong AR, Wolfe RA, Pappas A, Bohrer G, Miller CS, Wrighton KC.
PMID: 31796563
mSystems. 2019 Dec 03;4(6). doi: 10.1128/mSystems.00320-19.

Wetland soils are one of the largest natural contributors to the emission of methane, a potent greenhouse gas. Currently, microbial contributions to methane emissions from these systems emphasize the roles of acetoclastic and hydrogenotrophic methanogens, while less frequently considering...

Apollo lunar module engine exhaust products.

Science (New York, N.Y.)

Simoneit BR, Burlingame AL, Flory DA, Smith ID.
PMID: 17776759
Science. 1969 Nov 07;166(3906):733-8. doi: 10.1126/science.166.3906.733.

Organic combustion products generated by the lunar module descent engine, which burns a 1:1 mixture of unsymmetrical dimethylhydrazine fuel and nitrogen tetroxide oxidizer, have been analyzed. The major gaseous combustion products found were ammonia, water, carbon monoxide, nitrous oxide,...

Ethylenediamine on Ge(100)-2 x 1: the role of interdimer interactions.

The journal of physical chemistry. B

Kim A, Filler MA, Kim S, Bent SF.
PMID: 16853562
J Phys Chem B. 2005 Oct 27;109(42):19817-22. doi: 10.1021/jp054340o.

We have investigated the reaction of the bifunctional molecule ethylenediamine on Ge(100)-2 x 1 using multiple internal reflection Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and density functional theory calculations. Ethylenediamine exhibits different adsorption behavior than simple methylamines on...

Showing 25 to 36 of 52 entries