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Assessing usability, label comprehension, pen robustness and pharmacokinetics of a self-administered prefilled autoinjector pen of methotrexate in patients with rheumatoid arthritis.

SAGE open medicine

Pachon JA, Kivitz AJ, Heuer KU, Pichlmeier U.
PMID: 26770759
SAGE Open Med. 2014 Dec 22;2:2050312114564241. doi: 10.1177/2050312114564241. eCollection 2014.

OBJECTIVE: To assess usability, bioavailability, and safety of subcutaneous self-administration of 0.3 mL of methotrexate 50 mg/mL solution via a prefilled autoinjector pen (methotrexate pen) in patients with rheumatoid arthritis.METHODS: The study enrolled methotrexate-naïve and methotrexate-experienced patients aged ≥16...

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Pachon JA, Kivitz AJ, Heuer KU, et al. Assessing usability, label comprehension, pen robustness and pharmacokinetics of a self-administered prefilled autoinjector pen of methotrexate in patients with rheumatoid arthritis. SAGE Open Med. 2014;2:2050312114564241doi: 10.1177/2050312114564241.
Pachon, J. A., Kivitz, A. J., Heuer, K. U., & Pichlmeier, U. (2014). Assessing usability, label comprehension, pen robustness and pharmacokinetics of a self-administered prefilled autoinjector pen of methotrexate in patients with rheumatoid arthritis. SAGE open medicine, 22050312114564241. https://doi.org/10.1177/2050312114564241
Pachon, Jaime A, et al. "Assessing usability, label comprehension, pen robustness and pharmacokinetics of a self-administered prefilled autoinjector pen of methotrexate in patients with rheumatoid arthritis." SAGE open medicine vol. 2 (2014): 2050312114564241. doi: https://doi.org/10.1177/2050312114564241
Pachon JA, Kivitz AJ, Heuer KU, Pichlmeier U. Assessing usability, label comprehension, pen robustness and pharmacokinetics of a self-administered prefilled autoinjector pen of methotrexate in patients with rheumatoid arthritis. SAGE Open Med. 2014 Dec 22;2:2050312114564241. doi: 10.1177/2050312114564241. eCollection 2014. PMID: 26770759; PMCID: PMC4712753.
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A rare case of juvenile localised scleroderma with intra-oral and dental involvement.

Experimental and therapeutic medicine

Wang P, Guo W, Liu S.
PMID: 26668618
Exp Ther Med. 2015 Dec;10(6):2213-2215. doi: 10.3892/etm.2015.2791. Epub 2015 Oct 12.

Juvenile localised scleroderma is a rare childhood disorder of the immune system and connective tissue with unknown etiology. There are different types of localised scleroderma, including linear scleroderma (where the lesion appears as a line or streak) and plaque...

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Wang P, Guo W, Liu S. A rare case of juvenile localised scleroderma with intra-oral and dental involvement. Exp Ther Med. 2015;10(6):2213-2215doi: 10.3892/etm.2015.2791.
Wang, P., Guo, W., & Liu, S. (2015). A rare case of juvenile localised scleroderma with intra-oral and dental involvement. Experimental and therapeutic medicine, 10(6), 2213-2215. https://doi.org/10.3892/etm.2015.2791
Wang, Peng, et al. "A rare case of juvenile localised scleroderma with intra-oral and dental involvement." Experimental and therapeutic medicine vol. 10,6 (2015): 2213-2215. doi: https://doi.org/10.3892/etm.2015.2791
Wang P, Guo W, Liu S. A rare case of juvenile localised scleroderma with intra-oral and dental involvement. Exp Ther Med. 2015 Dec;10(6):2213-2215. doi: 10.3892/etm.2015.2791. Epub 2015 Oct 12. PMID: 26668618; PMCID: PMC4665754.
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Elephantine Psoriasis with Papillomatosis and Alternating Hypogranulosis and Hypergranulosis.

Indian journal of dermatology

Koley S, Mandal RK, Chatterjee K, Hassan SM, Pathak S.
PMID: 26120152
Indian J Dermatol. 2015 May-Jun;60(3):264-7. doi: 10.4103/0019-5154.156367.

Psoriasis is a disease of considerable clinical and histopathological diversity. We report a rare case of elephantine psoriasis responding very well to methotrexate. Histopathology revealed abnormal papillomatosis with finger-like projections in addition to alternating orthokeratosis with overlying hypergranulosis and...

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Koley S, Mandal RK, Chatterjee K, et al. Elephantine Psoriasis with Papillomatosis and Alternating Hypogranulosis and Hypergranulosis. Indian J Dermatol. 2015;60(3):264-7doi: 10.4103/0019-5154.156367.
Koley, S., Mandal, R. K., Chatterjee, K., Hassan, S. M., & Pathak, S. (2015). Elephantine Psoriasis with Papillomatosis and Alternating Hypogranulosis and Hypergranulosis. Indian journal of dermatology, 60(3), 264-7. https://doi.org/10.4103/0019-5154.156367
Koley, Sankha, et al. "Elephantine Psoriasis with Papillomatosis and Alternating Hypogranulosis and Hypergranulosis." Indian journal of dermatology vol. 60,3 (2015): 264-7. doi: https://doi.org/10.4103/0019-5154.156367
Koley S, Mandal RK, Chatterjee K, Hassan SM, Pathak S. Elephantine Psoriasis with Papillomatosis and Alternating Hypogranulosis and Hypergranulosis. Indian J Dermatol. 2015 May-Jun;60(3):264-7. doi: 10.4103/0019-5154.156367. PMID: 26120152; PMCID: PMC4458937.
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Idiopathic hypereosinophilic syndrome: a rare cause of erythroderma.

Journal of dermatological case reports

Mahajan VK, Singh R, Mehta KS, Chauhan PS, Sharma S, Gupta M, Rawat R.
PMID: 25621091
J Dermatol Case Rep. 2014 Dec 31;8(4):108-14. doi: 10.3315/jdcr.2014.1185. eCollection 2014 Dec 31.

BACKGROUND: Idiopathic hypereosinophilic syndrome (HES) is a rare and potentially lethal disorder characterized by persistently elevated eosinophil counts without any underlying causes. Two variants, the myeloproliferative and lymphocytic hypereosinophilic syndrome, have been identified. The symptoms are variable and related...

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Mahajan VK, Singh R, Mehta KS, et al. Idiopathic hypereosinophilic syndrome: a rare cause of erythroderma. J Dermatol Case Rep. 2014;8(4):108-14doi: 10.3315/jdcr.2014.1185.
Mahajan, V. K., Singh, R., Mehta, K. S., Chauhan, P. S., Sharma, S., Gupta, M., & Rawat, R. (2014). Idiopathic hypereosinophilic syndrome: a rare cause of erythroderma. Journal of dermatological case reports, 8(4), 108-14. https://doi.org/10.3315/jdcr.2014.1185
Mahajan, Vikram K, et al. "Idiopathic hypereosinophilic syndrome: a rare cause of erythroderma." Journal of dermatological case reports vol. 8,4 (2014): 108-14. doi: https://doi.org/10.3315/jdcr.2014.1185
Mahajan VK, Singh R, Mehta KS, Chauhan PS, Sharma S, Gupta M, Rawat R. Idiopathic hypereosinophilic syndrome: a rare cause of erythroderma. J Dermatol Case Rep. 2014 Dec 31;8(4):108-14. doi: 10.3315/jdcr.2014.1185. eCollection 2014 Dec 31. PMID: 25621091; PMCID: PMC4299705.
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Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures.

RMD open

Kremer JM, Lawrence DA, Hamilton R, McInnes IB.
PMID: 27335660
RMD Open. 2016 Jun 09;2(1):e000287. doi: 10.1136/rmdopen-2016-000287. eCollection 2016.

OBJECTIVE: To describe changes in immune parameters observed during long-term methotrexate (MTX) therapy in patients with active rheumatoid arthritis (RA) and explore correlations with simultaneously measured MTX pharmacokinetic (PKC) parameters.DESIGN: Prospective, open-label, long-term mechanism of action study.SETTING: University clinic.METHODS:...

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Kremer JM, Lawrence DA, Hamilton R, et al. Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures. RMD Open. 2016;2(1):e000287doi: 10.1136/rmdopen-2016-000287.
Kremer, J. M., Lawrence, D. A., Hamilton, R., & McInnes, I. B. (2016). Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures. RMD open, 2(1), e000287. https://doi.org/10.1136/rmdopen-2016-000287
Kremer, Joel M, et al. "Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures." RMD open vol. 2,1 (2016): e000287. doi: https://doi.org/10.1136/rmdopen-2016-000287
Kremer JM, Lawrence DA, Hamilton R, McInnes IB. Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures. RMD Open. 2016 Jun 09;2(1):e000287. doi: 10.1136/rmdopen-2016-000287. eCollection 2016. PMID: 27335660; PMCID: PMC4913203.
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[Focus on Crohn's disease].

Presse medicale (Paris, France : 1983)

Klotz C, Dhooge M, Oudjit A, Barret M, Beuvon F, Chaussade S, Coriat R, Abitbol V.
PMID: 25622513
Presse Med. 2015 Apr;44(4):411-7. doi: 10.1016/j.lpm.2014.07.028. Epub 2015 Jan 23.

Crohn's disease is an inflammatory bowel disease that affects the entire digestive tract, from the mouth to the anus. The inflammatory disease is transmural and may be complicated by abscesses, fistulas, strictures. Budesonide is used as first-line treatment for...

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Klotz C, Dhooge M, Oudjit A, et al. Prise en charge de la maladie de Crohn. [Focus on Crohn's disease]. Presse Med. 2015;44(4):411-7doi: 10.1016/j.lpm.2014.07.028.
Klotz, C., Dhooge, M., Oudjit, A., Barret, M., Beuvon, F., Chaussade, S., Coriat, R., & Abitbol, V. (2015). Prise en charge de la maladie de Crohn. [Focus on Crohn's disease]. Presse medicale (Paris, France : 1983), 44(4), 411-7. https://doi.org/10.1016/j.lpm.2014.07.028
Klotz, Caroline, et al. "Prise en charge de la maladie de Crohn." [Focus on Crohn's disease]. Presse medicale (Paris, France : 1983) vol. 44,4 (2015): 411-7. doi: https://doi.org/10.1016/j.lpm.2014.07.028
Klotz C, Dhooge M, Oudjit A, Barret M, Beuvon F, Chaussade S, Coriat R, Abitbol V. Prise en charge de la maladie de Crohn. [Focus on Crohn's disease]. Presse Med. 2015 Apr;44(4):411-7. doi: 10.1016/j.lpm.2014.07.028. Epub 2015 Jan 23. French. PMID: 25622513.
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Refractory optic perineuritis due to granulomatosis with polyangiitis successfully treated with methotrexate and mycophenolate mofetil combination therapy.

European journal of rheumatology

Kimura Y, Asako K, Kikuchi H, Kono H.
PMID: 28293459
Eur J Rheumatol. 2017 Mar;4(1):70-72. doi: 10.5152/eurjrheum.2016.028. Epub 2017 Mar 01.

Optic perineuritis is an uncommon inflammatory disorder of the optic sheath that causes visual loss or eye pain. There are few case reports of optic perineuritis associated with granulomatosis with polyangiitis. Herein we report the case of a 37-year-old...

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Kimura Y, Asako K, Kikuchi H, et al. Refractory optic perineuritis due to granulomatosis with polyangiitis successfully treated with methotrexate and mycophenolate mofetil combination therapy. Eur J Rheumatol. 2017;4(1):70-72doi: 10.5152/eurjrheum.2016.028.
Kimura, Y., Asako, K., Kikuchi, H., & Kono, H. (2017). Refractory optic perineuritis due to granulomatosis with polyangiitis successfully treated with methotrexate and mycophenolate mofetil combination therapy. European journal of rheumatology, 4(1), 70-72. https://doi.org/10.5152/eurjrheum.2016.028
Kimura, Yoshitaka, et al. "Refractory optic perineuritis due to granulomatosis with polyangiitis successfully treated with methotrexate and mycophenolate mofetil combination therapy." European journal of rheumatology vol. 4,1 (2017): 70-72. doi: https://doi.org/10.5152/eurjrheum.2016.028
Kimura Y, Asako K, Kikuchi H, Kono H. Refractory optic perineuritis due to granulomatosis with polyangiitis successfully treated with methotrexate and mycophenolate mofetil combination therapy. Eur J Rheumatol. 2017 Mar;4(1):70-72. doi: 10.5152/eurjrheum.2016.028. Epub 2017 Mar 01. PMID: 28293459; PMCID: PMC5335893.
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Arteriovenous Fistula Embolization in Suspected Parauterine Choriocarcinoma.

Case reports in obstetrics and gynecology

Alturkistani H, Almarzooqi MK, Oliva V, Gilbert P.
PMID: 27403360
Case Rep Obstet Gynecol. 2016;2016:6353471. doi: 10.1155/2016/6353471. Epub 2016 Jun 14.

This is a case of choriocarcinoma that did not regress after chemotherapy treatment. A 30-year-old female patient (gravida 2, para 2), presented to our ER with stroke and persistent mild pelvic pain 2 months after a Caesarean section. Computed...

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Alturkistani H, Almarzooqi MK, Oliva V, et al. Arteriovenous Fistula Embolization in Suspected Parauterine Choriocarcinoma. Case Rep Obstet Gynecol. 2016;2016:6353471doi: 10.1155/2016/6353471.
Alturkistani, H., Almarzooqi, M. K., Oliva, V., & Gilbert, P. (2016). Arteriovenous Fistula Embolization in Suspected Parauterine Choriocarcinoma. Case reports in obstetrics and gynecology, 20166353471. https://doi.org/10.1155/2016/6353471
Alturkistani, Husain, et al. "Arteriovenous Fistula Embolization in Suspected Parauterine Choriocarcinoma." Case reports in obstetrics and gynecology vol. 2016 (2016): 6353471. doi: https://doi.org/10.1155/2016/6353471
Alturkistani H, Almarzooqi MK, Oliva V, Gilbert P. Arteriovenous Fistula Embolization in Suspected Parauterine Choriocarcinoma. Case Rep Obstet Gynecol. 2016;2016:6353471. doi: 10.1155/2016/6353471. Epub 2016 Jun 14. PMID: 27403360; PMCID: PMC4923520.
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Successful Management of Live Cervical Ectopic Pregnancy: A Case Report.

Journal of clinical and diagnostic research : JCDR

Samal S, Ghose S, Pallavee P, Porkkodi P.
PMID: 26816951
J Clin Diagn Res. 2015 Dec;9(12):QD03-4. doi: 10.7860/JCDR/2015/12230.6871. Epub 2015 Dec 01.

Cervical pregnancy is a rare form of ectopic pregnancy with potential grave consequences occurring in approximately 1:9,000 deliveries. It is life-threatening as the pregnancy is implanted in the endocervical canal and the trophoblast can penetrate through the cervical wall...

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Samal S, Ghose S, Pallavee P, et al. Successful Management of Live Cervical Ectopic Pregnancy: A Case Report. J Clin Diagn Res. 2015;9(12):QD03-4doi: 10.7860/JCDR/2015/12230.6871.
Samal, S., Ghose, S., Pallavee, P., & Porkkodi, P. (2015). Successful Management of Live Cervical Ectopic Pregnancy: A Case Report. Journal of clinical and diagnostic research : JCDR, 9(12), QD03-4. https://doi.org/10.7860/JCDR/2015/12230.6871
Samal, Sunita, et al. "Successful Management of Live Cervical Ectopic Pregnancy: A Case Report." Journal of clinical and diagnostic research : JCDR vol. 9,12 (2015): QD03-4. doi: https://doi.org/10.7860/JCDR/2015/12230.6871
Samal S, Ghose S, Pallavee P, Porkkodi P. Successful Management of Live Cervical Ectopic Pregnancy: A Case Report. J Clin Diagn Res. 2015 Dec;9(12):QD03-4. doi: 10.7860/JCDR/2015/12230.6871. Epub 2015 Dec 01. PMID: 26816951; PMCID: PMC4717703.
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Methotrexate-associated primary hepatic malignant lymphoma following hepatectomy: A case report.

International journal of surgery case reports

Takei D, Abe T, Amano H, Hirano N, Kobayashi T, Ohdan H, Kondo T, Nakahara M, Noriyuki T.
PMID: 28076752
Int J Surg Case Rep. 2017;31:5-9. doi: 10.1016/j.ijscr.2016.12.012. Epub 2016 Dec 21.

INTRODUCTION: Recently, immunosuppressant-associated malignant lymphoma (ML) cases have been increasing along with the development of several effective immunosuppressant drugs for rheumatoid arthritis (RA). Among methotrexate (MTX)-associated lymphoproliferative disorders, primary hepatic lymphoma (PHL) in patients with RA following surgical resection...

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Takei D, Abe T, Amano H, et al. Methotrexate-associated primary hepatic malignant lymphoma following hepatectomy: A case report. Int J Surg Case Rep. 2016;31:5-9doi: 10.1016/j.ijscr.2016.12.012.
Takei, D., Abe, T., Amano, H., Hirano, N., Kobayashi, T., Ohdan, H., Kondo, T., Nakahara, M., & Noriyuki, T. (2017). Methotrexate-associated primary hepatic malignant lymphoma following hepatectomy: A case report. International journal of surgery case reports, 315-9. https://doi.org/10.1016/j.ijscr.2016.12.012
Takei, Daisuke, et al. "Methotrexate-associated primary hepatic malignant lymphoma following hepatectomy: A case report." International journal of surgery case reports vol. 31 (2017): 5-9. doi: https://doi.org/10.1016/j.ijscr.2016.12.012
Takei D, Abe T, Amano H, Hirano N, Kobayashi T, Ohdan H, Kondo T, Nakahara M, Noriyuki T. Methotrexate-associated primary hepatic malignant lymphoma following hepatectomy: A case report. Int J Surg Case Rep. 2017;31:5-9. doi: 10.1016/j.ijscr.2016.12.012. Epub 2016 Dec 21. PMID: 28076752; PMCID: PMC5222945.
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Could Spinal Canal Compression be a Cause of Polyneuropathy?.

Clinics and practice

Bostelmann R, Zella S, Steiger HJ, Petridis AK.
PMID: 27162603
Clin Pract. 2016 Apr 11;6(1):816. doi: 10.4081/cp.2016.816. eCollection 2016 Mar 25.

Causality between spinal cord compression and polyneuropathy is difficult to define, especially under the circumstances that polyneuropathy can have many causes. Seven patients with spinal cord compression and electrophysiological signs of polyneuropathy were treated surgically on decompression of their...

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Bostelmann R, Zella S, Steiger HJ, et al. Could Spinal Canal Compression be a Cause of Polyneuropathy?. Clin Pract. 2016;6(1):816doi: 10.4081/cp.2016.816.
Bostelmann, R., Zella, S., Steiger, H. J., & Petridis, A. K. (2016). Could Spinal Canal Compression be a Cause of Polyneuropathy?. Clinics and practice, 6(1), 816. https://doi.org/10.4081/cp.2016.816
Bostelmann, Richard, et al. "Could Spinal Canal Compression be a Cause of Polyneuropathy?." Clinics and practice vol. 6,1 (2016): 816. doi: https://doi.org/10.4081/cp.2016.816
Bostelmann R, Zella S, Steiger HJ, Petridis AK. Could Spinal Canal Compression be a Cause of Polyneuropathy?. Clin Pract. 2016 Apr 11;6(1):816. doi: 10.4081/cp.2016.816. eCollection 2016 Mar 25. PMID: 27162603; PMCID: PMC4844812.
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Good tolerance of high dose cytosine arabinoside and methotrexate after severe myelosuppression secondary to intrathecal administration of the same agents.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Yıldırım N, Abalı H, Güler T, Öksüzoğlu B, Pamukçu M, Zengin N.
PMID: 27263773
Turk J Haematol. 2007 Sep 05;24(3):140-1.

No abstract available.

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Yıldırım N, Abalı H, Güler T, et al. Good tolerance of high dose cytosine arabinoside and methotrexate after severe myelosuppression secondary to intrathecal administration of the same agents. Turk J Haematol. 2007;24(3):140-1
Yıldırım, N., Abalı, H., Güler, T., Öksüzoğlu, B., Pamukçu, M., & Zengin, N. (2007). Good tolerance of high dose cytosine arabinoside and methotrexate after severe myelosuppression secondary to intrathecal administration of the same agents. Turkish journal of haematology : official journal of Turkish Society of Haematology, 24(3), 140-1.
Yıldırım, Nuriye, et al. "Good tolerance of high dose cytosine arabinoside and methotrexate after severe myelosuppression secondary to intrathecal administration of the same agents." Turkish journal of haematology : official journal of Turkish Society of Haematology vol. 24,3 (2007): 140-1.
Yıldırım N, Abalı H, Güler T, Öksüzoğlu B, Pamukçu M, Zengin N. Good tolerance of high dose cytosine arabinoside and methotrexate after severe myelosuppression secondary to intrathecal administration of the same agents. Turk J Haematol. 2007 Sep 05;24(3):140-1. PMID: 27263773.
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Showing 25 to 36 of 4525 entries