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Showing 13 to 24 of 224 entries
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Video-assisted thoracoscopy the total mesoesophageal excision and systematic en bloc mediastinal lymph node dissection.

Journal of visualized surgery

Kang M, Huang S, Lin J, Chen S, Lin J, Han W.
PMID: 29399489
J Vis Surg. 2016 May 30;2:102. doi: 10.21037/jovs.2016.05.03. eCollection 2016.

A 59-year-old female presented with upper esophageal squamous cell carcinoma had swallowing disorders. We performed the total mesoesophageal excision (TME) and systematic en bloc mediastinal lymph node dissection via VATS. The surgery process was successful and the postoperative course...

Development and Characterization of a Semi-Solid Dosage Form of Meglumine Antimoniate for Topical Treatment of Cutaneous Leishmaniasis.

Pharmaceutics

Berenguer D, Sosa L, Alcover M, Sessa M, Halbaut L, Guillén C, Fisa R, Calpena-Campmany AC, Riera C.
PMID: 31731660
Pharmaceutics. 2019 Nov 15;11(11). doi: 10.3390/pharmaceutics11110613.

Cutaneous leishmaniasis (CL) is treated with painful intralesional injections of meglumine antimoniate (MA). With the aim of developing an alternative topical treatment for CL, a gel-based formulation with 30% MA was prepared and its physicochemical properties, stability and rheological...

rCBV- and ADC-based Grading of Meningiomas With Glimpse Into Emerging Molecular Diagnostics.

Basic and clinical neuroscience

Rohilla S, Garg HK, Singh I, Yadav RK, Dhaulakhandi DB.
PMID: 30719256
Basic Clin Neurosci. 2018 Nov-Dec;9(6):417-428. doi: 10.32598/bcn.9.6.417. Epub 2018 Nov 01.

INTRODUCTION: This study was conducted to grade meningiomas based on relative Cerebral Blood Volume (rCBV) and Apparent Diffusion Coefficient (ADC) to help surgeons plan the approach and extent of operation as well as decide on the need of any...

Management Strategy of Meconium Ileus-Outcome Analysis.

Journal of Indian Association of Pediatric Surgeons

Singh AK, Pandey A, Rawat J, Singh S, Wakhlu A, Kureel SN.
PMID: 31105398
J Indian Assoc Pediatr Surg. 2019 Apr-Jun;24(2):120-123. doi: 10.4103/jiaps.JIAPS_41_18.

BACKGROUND: Meconium ileus (MI) is defined as an intestinal obstruction caused by the impaction of inspissated meconium in the terminal ileum. In this study, we have evaluated the nonoperative management of patients of simple MI without fluoroscopic support -an...

Development and characterization of liposomal formulation of bortezomib.

International journal of pharmaceutics: X

Deshantri AK, Metselaar JM, Zagkou S, Storm G, Mandhane SN, Fens MHAM, Schiffelers RM.
PMID: 31517276
Int J Pharm X. 2019 Mar 23;1:100011. doi: 10.1016/j.ijpx.2019.100011. eCollection 2019 Dec.

Bortezomib is a proteasome inhibitor used for the treatment of multiple myeloma. The poor pharmacokinetic profile and off-target adverse effects provide a strong incentive to develop drug delivery systems for bortezomib. In the past, liposomal encapsulation has been proven...

Use of Diterpene Ginkgolides Meglumine Injection to Regulate Plasma Levels of PAI-1 and t-PA in Patients With Acute Atherosclerotic Cerebral Infarction.

The neurologist

Chen R, Yan L, Xie P, Tian J, Zhao Y, Liu Y, Xu J, Wang Y, Zhao L.
PMID: 34855657
Neurologist. 2021 Nov 30; doi: 10.1097/NRL.0000000000000399. Epub 2021 Nov 30.

BACKGROUND: To: (i) explore the effect of diterpene ginkgolides meglumine injection (DGMI) on neurological deficit symptoms in acute atherosclerotic cerebral infarction (AACI) patients; (ii) measure the level of plasma plasminogen activator inhibitor (PAI)-1 and tissue plasminogen activator (t-PA).METHODS: Eighty...

Meglumine Antimoniate-Loaded Aqueous-Core PLA Nanocapsules: Old Drug, New Formulation against Leishmania-Related Diseases.

Macromolecular bioscience

Cosco D, Bruno F, Castelli G, Puleio R, Bonacci S, Procopio A, Britti D, Fresta M, Vitale F, Paolino D.
PMID: 34117834
Macromol Biosci. 2021 Jul;21(7):e2100046. doi: 10.1002/mabi.202100046. Epub 2021 Jun 12.

Leishmaniasis is a human and animal disease endemic in tropical and subtropical areas treated by means of pentavalent antimony as first-line approach. Unfortunately, the formulations available on the market are characterized by significant side effects and a total remission...

Comparative evaluation of meglumine antimoniate encapsulated in a mixture of conventional and PEGylated liposomes and immunotherapy using an anti-canine IL-10 receptor-blocking monoclonal antibody on canine visceral leishmaniasis.

Molecular immunology

Cardoso JMO, Brito RCF, Mathias FAS, Reis LES, Vieira JFP, Ostolin TLVDP, Andrade HM, Ramos GS, Frézard F, Aguiar-Soares RDO, Roatt BM, Reis AB.
PMID: 34814056
Mol Immunol. 2021 Nov 20;141:70-78. doi: 10.1016/j.molimm.2021.11.011. Epub 2021 Nov 20.

This study compared the therapeutic potential of the chemotherapy using meglumine antimoniate encapsulated in a mixture of conventional and PEGylated liposomes (Nano Sb

Can Deep Learning Replace Gadolinium in Neuro-Oncology?: A Reader Study.

Investigative radiology

Ammari S, Bône A, Balleyguier C, Moulton E, Chouzenoux É, Volk A, Menu Y, Bidault F, Nicolas F, Robert P, Rohé MM, Lassau N.
PMID: 34324463
Invest Radiol. 2022 Feb 01;57(2):99-107. doi: 10.1097/RLI.0000000000000811.

MATERIALS AND METHODS: This monocentric retrospective study leveraged 200 multiparametric brain MRIs acquired between November 2019 and February 2020 at Gustave Roussy Cancer Campus (Villejuif, France). A total of 145 patients were included: 107 formed the training sample (55...

Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects.

PLoS neglected tropical diseases

Henry K, Mayet A, Hernandez M, Frechard G, Blanc PA, Schmitt M, André N, Loreau JM, Ginouves M, Prévot G, Couppié P, Demar M, Blaizot R.
PMID: 34797836
PLoS Negl Trop Dis. 2021 Nov 19;15(11):e0009938. doi: 10.1371/journal.pntd.0009938. eCollection 2021 Nov.

BACKGROUND: Cutaneous Leishmaniasis (CL) is endemic in French Guiana but cases are usually sporadic. An outbreak signal was issued on May 15th 2020 with 15 suspected cases after a military training course in the rainforest. An outbreak investigation was...

Feasibility of micropollutants removal by solar-activated persulfate: Reactive oxygen species formation and influence on DBPs.

Water research

Tan C, Zhao H, Wang X, Yu H, Chong S, Xu Y, Du E, Chen M, Peng X, Su L.
PMID: 34952455
Water Res. 2021 Dec 19;210:117981. doi: 10.1016/j.watres.2021.117981. Epub 2021 Dec 19.

As a natural source of visible light and a type of renewable energy, solar energy is extensively used in the field of photochemistry. In this study, solar was employed to activate persulfate (PS) to degrade typical micropollutants. The removal...

Comparative evaluation of meglumine antimoniate encapsulated in a mixture of conventional and PEGylated liposomes and immunotherapy using an anti-canine IL-10 receptor-blocking monoclonal antibody on canine visceral leishmaniasis.

Molecular immunology

Cardoso JMO, Brito RCF, Mathias FAS, Reis LES, Vieira JFP, Ostolin TLVDP, Andrade HM, Ramos GS, Frézard F, Aguiar-Soares RDO, Roatt BM, Reis AB.
PMID: 34814056
Mol Immunol. 2021 Nov 20;141:70-78. doi: 10.1016/j.molimm.2021.11.011. Epub 2021 Nov 20.

This study compared the therapeutic potential of the chemotherapy using meglumine antimoniate encapsulated in a mixture of conventional and PEGylated liposomes (Nano Sb

Showing 13 to 24 of 224 entries