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Showing 25 to 36 of 209 entries
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Significant cardiac disease complicating Graves' disease in previously healthy young adults.

Endocrinology, diabetes & metabolism case reports

Witczak JK, Ubaysekara N, Ravindran R, Rice S, Yousef Z, Premawardhana LD.
PMID: 31967967
Endocrinol Diabetes Metab Case Rep. 2020 Jan 22;2020. doi: 10.1530/EDM-19-0132. Epub 2020 Jan 22.

SUMMARY: Graves' disease is associated with tachydysrythmia, cardiac ischaemia and cardiomyopathy - all uncommon in young adults without previous cardiac disease. We present three young individuals who developed cardiac complications after periods of uncontrolled Graves' disease. Subject 1: A...

Figure of 3-sign: a case report.

European heart journal. Case reports

Henzel AW, Schwerzmann M.
PMID: 31020238
Eur Heart J Case Rep. 2018 Dec 27;3(1):yty162. doi: 10.1093/ehjcr/yty162. eCollection 2019 Mar.

BACKGROUND: A 50-year-old mother of four children was newly diagnosed with arterial hypertension and bilateral neck pulsations.CASE SUMMARY: Her current blood pressure was 170/100 mmHg in the right arm and 122 mmHg systolic in the right ankle. There was...

ACE inhibitor-associated intestinal angioedema in orthotopic heart transplantation.

ESC heart failure

Srinivasan D, Strohbehn GW, Cascino T.
PMID: 28772029
ESC Heart Fail. 2017 Aug;4(3):384-386. doi: 10.1002/ehf2.12161. Epub 2017 Mar 23.

Angiotensin-converting enzyme inhibitor induced angioedema commonly involves the head and neck area. We report a case of angiotensin-converting enzyme inhibitor induced intestinal angioedema in a heart transplant recipient on mTOR immunosuppression. A 36-year-old Caucasian woman with history of heart...

Comparative proteinuria management of different angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for normotensive patients with CKD: a Bayesian network meta-analysis.

PeerJ

Ye H, Huo Z, Ye P, Xiao G, Zhang Z, Xie C, Kong Y.
PMID: 32201639
PeerJ. 2020 Mar 12;8:e8575. doi: 10.7717/peerj.8575. eCollection 2020.

BACKGROUND: Both angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are blood pressure-lowering agents, but they are also being used to control proteinuria in early chronic kidney disease (CKD) patients. However, clinically, some patients present merely proteinuria without...

An Unexpected Case of Lisinopril-Associated Severe Hyponatremia.

Cureus

Jiang Y, Cai W, Masquelin ME, Gordon K.
PMID: 32782860
Cureus. 2020 Jul 07;12(7):e9039. doi: 10.7759/cureus.9039.

Angiotensin-converting enzyme (ACE) inhibitors are a class of medications that have formed the backbone of hypertension management. Of these medications, lisinopril is one of the most commonly used. While known serious side effects of all ACE inhibitors include angioedema...

Molecular Changes in miRNA in Irradiated Rat Kidneys: Role of miR-34a and its Vascular Targets in the Notch Pathway.

Radiation research

Gao F, Dong W, Liu P, Narayanan J, Fish BL, Jacobs ER, Medhora M.
PMID: 34330145
Radiat Res. 2021 Dec 01;196(6):611-622. doi: 10.1667/RADE-20-00078.1.

The mechanism(s) of vascular regression in adult organs remains an unexplored gap. Irradiation to the kidney results in vascular regression and renal failure. The goal of this work was to determine molecular mechanism(s) of radiation-induced vascular regression and its...

A Pharmacovigilance Study of Adverse Drug Reactions Reported for Cardiovascular Disease Medications Approved Between 2012 and 2017 in the United States Food and Drug Administration Adverse Event Reporting System (FAERS) Database.

Cardiovascular drugs and therapy

Patel NM, Stottlemyer BA, Gray MP, Boyce RD, Kane-Gill SL.
PMID: 33599896
Cardiovasc Drugs Ther. 2021 Feb 18; doi: 10.1007/s10557-021-07157-3. Epub 2021 Feb 18.

PURPOSE: Between 2012 and 2017, the FDA approved 29 therapies for a cardiovascular disease (CVD) indication. Due to the limited literature on patient safety outcomes for recently approved CVD medications, this study investigated adverse drug reports (ADRs) reported in...

Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure.

Frontiers in physiology

Brown AK, Nichols A, Coley CA, Ekperikpe US, McPherson KC, Shields CA, Poudel B, Cornelius DC, Williams JM.
PMID: 34975523
Front Physiol. 2021 Dec 17;12:765305. doi: 10.3389/fphys.2021.765305. eCollection 2021.

Recently, we reported that obese Dahl salt-sensitive leptin receptor mutant (SS

Investigation of inhibition effect of butanol and water extracts of Matricaria chamomilla L. on angiotensin-converting enzyme purified from human plasma.

Biotechnology and applied biochemistry

Bas Z, Turkoglu V, Goz Y.
PMID: 33438805
Biotechnol Appl Biochem. 2021 Jan 13; doi: 10.1002/bab.2106. Epub 2021 Jan 13.

Angiotensin-converting enzyme (ACE) liable for the regulation of blood pressure was purified from human plasma by affinity chromatography. Impact of water and butanol extracts of Matricaria chamomilla L. on purity ACE was examined. ACE was purified using the affinity...

Chaotropic salts impact in HPLC approaches for simultaneous analysis of hydrophilic and lipophilic drugs.

Journal of separation science

Shulyak N, Piponski M, Kovalenko S, Stoimenova TB, Drapak I, Piponska M, Rezk MR, Abbeyquaye AD, Oleshchuk O, Logoyda L.
PMID: 34047016
J Sep Sci. 2021 Aug;44(15):2908-2916. doi: 10.1002/jssc.202100168. Epub 2021 Jun 17.

Simultaneous determination of drugs with different physicochemical properties necessitates thorough research and careful selection of high-performance liquid chromatography conditions. In the present study, various concepts of high-performance liquid chromatography method development for this aim have been discussed. Moreover, the...

Corrigendum: Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes.

Frontiers in pharmacology

Gasperetti T, Miller T, Gao F, Narayanan J, Jacobs ER, Szabo A, Cox GN, Orschell CM, Fish BL, Medhora M.
PMID: 34512365
Front Pharmacol. 2021 Aug 25;12:741485. doi: 10.3389/fphar.2021.741485. eCollection 2021.

[This corrects the article DOI: 10.3389/fphar.2021.634477.].

Characterization of ACE Inhibitors and AT.

Life (Basel, Switzerland)

Reus P, Schneider AK, Ulshöfer T, Henke M, Bojkova D, Cinatl J, Ciesek S, Geisslinger G, Laux V, Grättinger M, Gribbon P, Schiffmann S.
PMID: 34440554
Life (Basel). 2021 Aug 10;11(8). doi: 10.3390/life11080810.

Blood-pressure-lowering drugs are proposed to foster SARS-CoV-2 infection by pharmacological upregulation of angiotensin-converting enzyme 2 (ACE2), the binding partner of the virus spike (S) protein, located on the surface of the host cells. Conversely, it is postulated that angiotensin-renin...

Showing 25 to 36 of 209 entries