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Showing 193 to 204 of 209 entries
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The AT-1 Angiotensin Receptor is Involved in the Autonomic and Neuroendocrine Responses to Acute Restraint Stress in Male Rats.

Cellular and molecular neurobiology

Brasil TFS, Belém-Filho IJA, Fortaleza EAT, Antunes-Rodrigues J, Corrêa FMA.
PMID: 33864194
Cell Mol Neurobiol. 2022 Jan;42(1):109-124. doi: 10.1007/s10571-021-01090-7. Epub 2021 Apr 16.

The renin-angiotensin system (RAS) is involved in cardiovascular and hydroelectrolytic control, being associated with the development of hypertension. The restraint stress (RS) model is an aversive situation, which promotes a sustained increase in blood pressure and heart rate, and...

Risk of hospitalized and non-hospitalized gastrointestinal bleeding in ALLHAT trial participants receiving diuretic, ACE-inhibitor, or calcium-channel blocker.

PloS one

Du XL, Simpson LM, Tandy BC, Bettencourt JL, Davis BR.
PMID: 34793552
PLoS One. 2021 Nov 18;16(11):e0260107. doi: 10.1371/journal.pone.0260107. eCollection 2021.

OBJECTIVES: This post-trial data linkage analysis was to utilize the data of Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) participants linked with their Medicare data to examine the risk of hospitalized and non-hospitalized gastrointestinal (GI) bleeding...

The Role of Lisinopril and Bisoprolol to Prevent Anthracycline Induced Cardiotoxicity in Locally Advanced Breast Cancer Patients.

Asian Pacific journal of cancer prevention : APJCP

Wihandono A, Azhar Y, Abdurahman M, Hidayat S.
PMID: 34582653
Asian Pac J Cancer Prev. 2021 Sep 01;22(9):2847-2853. doi: 10.31557/APJCP.2021.22.9.2847.

BACKGROUND: Anthracyclines are a class of chemotherapeutic agents that are used to treat many different cancers, including breast cancer. Although anthracyclines remain an effective and commonly used therapy, their use is limited by cardiotoxicity. Heart failure and left ventricular...

Evaluation of Dual Inhibitory Effect of Anagliptin, Ramipril, and Lisinopril on Angiotensin-Converting Enzyme and DPP-4 Activities.

Current molecular pharmacology

Abouelkheir M.
PMID: 34077352
Curr Mol Pharmacol. 2021 May 31; doi: 10.2174/1874467214666210601104117. Epub 2021 May 31.

BACKGROUND: We previously tested two angiotensin-converting enzyme (ACE) inhibitors and two dipeptidyl peptidase-4 (DPP-4) inhibitors for dual enzyme inhibitory effect. Only two DPP-4 inhibitors, linagliptin and sitagliptin, were able to inhibit ACE.OBJECTIVE: In the present study, we investigated if...

Selected Antihypertensive Agents and Their Fixed-Dose Combinations Effectively Ameliorate Trastuzumab-Mediated Cardiac Dysfunction In Rats.

Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria

Adeneye AA, Olorundare OE, Omobowale TO, Akinsola AO, Kolo PM, Albrecht RMA, Crooks PA.
PMID: 34987247
Niger J Physiol Sci. 2021 Jun 30;36(1):57-65.

This study evaluates the therapeutic potentials of selected antihypertensive drugs [valsartan, amlodipine, lisinopril and their fixed-dose combinations (amlodipine + lisinopril) and (valsartan + lisinopril)] in ameliorating trastuzumab (TZM)‑induced cardiac dysfunctions in experimental rats. After an ethical clearance for the...

Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure.

Frontiers in physiology

Brown AK, Nichols A, Coley CA, Ekperikpe US, McPherson KC, Shields CA, Poudel B, Cornelius DC, Williams JM.
PMID: 34975523
Front Physiol. 2021 Dec 17;12:765305. doi: 10.3389/fphys.2021.765305. eCollection 2021.

Recently, we reported that obese Dahl salt-sensitive leptin receptor mutant (SS

Effect of eplerenone, a selective aldosterone blocker, on the development of diabetic nephropathy in type 2 diabetic rats.

Diabetes & metabolism journal

Ahn JH, Hong HC, Cho MJ, Kim YJ, Choi HY, Eun CR, Yang SJ, Yoo HJ, Kim HY, Seo JA, Kim SG, Choi KM, Baik SH, Choi DS, Kim NH.
PMID: 22540049
Diabetes Metab J. 2012 Apr;36(2):128-35. doi: 10.4093/dmj.2012.36.2.128. Epub 2012 Apr 17.

BACKGROUND: Aldosterone antagonists are reported to have beneficial effects on diabetic nephropathy by effective blocking of the renin-angiotensin-aldosterone system. We investigated the renoprotective effect of the selective aldosterone receptor blocker eplerenone, the angiotensin converting enzyme inhibitor lisinopril, and combined...

Angioedema Caused by Drugs That Prevent the Degradation of Vasoactive Peptides: A Pharmacovigilance Database Study.

Journal of clinical medicine

Noguchi Y, Murayama A, Esaki H, Sugioka M, Koyama A, Tachi T, Teramachi H.
PMID: 34884209
J Clin Med. 2021 Nov 25;10(23). doi: 10.3390/jcm10235507.

Angioedema results from the decreased degradation of vasoactive peptides such as substance P and bradykinin. In this study, we sought to clarify whether dipeptidyl peptidase-4 (DPP-4) and angiotensin-converting enzyme (ACE) inhibitors that suppress the degradation of substance P and...

Impact of Lisinopril on Cardiometabolic Risk Factors in Men With Hypertension and Early-onset Androgenetic Alopecia: A Pilot Study.

Journal of cardiovascular pharmacology

Krysiak R, Basiak M, Okopień B.
PMID: 34321400
J Cardiovasc Pharmacol. 2021 Nov 01;78(5):e738-e742. doi: 10.1097/FJC.0000000000001113.

ABSTRACT: Women with polycystic ovary syndrome are at a high cardiometabolic risk. Early-onset male-pattern baldness is considered the phenotypic equivalent of polycystic ovary syndrome in men. The aim of this study was to assess whether early-onset androgenetic alopecia modifies...

The AT-1 Angiotensin Receptor is Involved in the Autonomic and Neuroendocrine Responses to Acute Restraint Stress in Male Rats.

Cellular and molecular neurobiology

Brasil TFS, Belém-Filho IJA, Fortaleza EAT, Antunes-Rodrigues J, Corrêa FMA.
PMID: 33864194
Cell Mol Neurobiol. 2021 Apr 16; doi: 10.1007/s10571-021-01090-7. Epub 2021 Apr 16.

The renin-angiotensin system (RAS) is involved in cardiovascular and hydroelectrolytic control, being associated with the development of hypertension. The restraint stress (RS) model is an aversive situation, which promotes a sustained increase in blood pressure and heart rate, and...

Oroesophageal Pemphigus vulgaris Secondary to Lisinopril Use: A New Side Effect.

Cureus

Tariq U, Nasrullah A, Guha A, Mitre M.
PMID: 33972894
Cureus. 2021 Apr 06;13(4):e14333. doi: 10.7759/cureus.14333.

Pemphigoid diseases are a group of blistering autoimmune pathologies including pemphigus vulgaris (PV) and pemphigus foliaceous, which affect mucocutaneous tissues. Non-steroidal anti-inflammatory drugs, penicillamine, and angiotensin-converting enzyme inhibitors such as captopril and enalapril are associated with drug-induced pemphigoid. We...

Once- Versus Twice-Daily Angiotensin-Converting Enzyme Inhibitors for Blood Pressure Control in Adult Patients With Hypertension.

Cureus

Fischer K, Diec S.
PMID: 34567875
Cureus. 2021 Aug 20;13(8):e17331. doi: 10.7759/cureus.17331. eCollection 2021 Aug.

This review aimed to assess the efficacy and safety of once- versus twice-daily administration of angiotensin-converting enzyme (ACE) inhibitors for the management of hypertension. A literature search on PubMed and Google Scholar was performed (January 1980 to June 2020)...

Showing 193 to 204 of 209 entries