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Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease.

Archives of medical research

Toledo-Ibelles P, Gutiérrez-Vidal R, Calixto-Tlacomulco S, Delgado-Coello B, Mas-Oliva J.
PMID: 33966916
Arch Med Res. 2021 Oct;52(7):692-702. doi: 10.1016/j.arcmed.2021.04.005. Epub 2021 May 06.

BACKGROUND: An elevated level of plasma uric acid has been widely recognized as a risk factor for non-alcoholic fatty liver disease (NAFLD), where oxidative stress and inflammation play an important role in the pathophysiology of the disease. Although the...

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Toledo-Ibelles P, Gutiérrez-Vidal R, Calixto-Tlacomulco S, et al. Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. Arch Med Res. 2021;52(7):692-702doi: 10.1016/j.arcmed.2021.04.005.
Toledo-Ibelles, P., Gutiérrez-Vidal, R., Calixto-Tlacomulco, S., Delgado-Coello, B., & Mas-Oliva, J. (2021). Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. Archives of medical research, 52(7), 692-702. https://doi.org/10.1016/j.arcmed.2021.04.005
Toledo-Ibelles, Paola, et al. "Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease." Archives of medical research vol. 52,7 (2021): 692-702. doi: https://doi.org/10.1016/j.arcmed.2021.04.005
Toledo-Ibelles P, Gutiérrez-Vidal R, Calixto-Tlacomulco S, Delgado-Coello B, Mas-Oliva J. Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. Arch Med Res. 2021 Oct;52(7):692-702. doi: 10.1016/j.arcmed.2021.04.005. Epub 2021 May 06. PMID: 33966916.
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Impact of sphingomyelin levels on coronary heart disease and left ventricular systolic function in humans.

Nutrition & metabolism

Chen X, Sun A, Zou Y, Ge J, Lazar JM, Jiang XC.
PMID: 21521522
Nutr Metab (Lond). 2011 Apr 26;8(1):25. doi: 10.1186/1743-7075-8-25.

Sphingomyelin (SM) is an abundant phospholipid in cell membranes and in lipoproteins. In human plasma, SM is mainly found in atherogenic lipoproteins; therefore, higher levels of SM may promote atherogenesis. We investigated the relations between plasma SM levels and...

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Chen X, Sun A, Zou Y, et al. Impact of sphingomyelin levels on coronary heart disease and left ventricular systolic function in humans. Nutr Metab (Lond). 2011;8(1):25doi: 10.1186/1743-7075-8-25.
Chen, X., Sun, A., Zou, Y., Ge, J., Lazar, J. M., & Jiang, X. C. (2011). Impact of sphingomyelin levels on coronary heart disease and left ventricular systolic function in humans. Nutrition & metabolism, 8(1), 25. https://doi.org/10.1186/1743-7075-8-25
Chen, Xueying, et al. "Impact of sphingomyelin levels on coronary heart disease and left ventricular systolic function in humans." Nutrition & metabolism vol. 8,1 (2011): 25. doi: https://doi.org/10.1186/1743-7075-8-25
Chen X, Sun A, Zou Y, Ge J, Lazar JM, Jiang XC. Impact of sphingomyelin levels on coronary heart disease and left ventricular systolic function in humans. Nutr Metab (Lond). 2011 Apr 26;8(1):25. doi: 10.1186/1743-7075-8-25. PMID: 21521522; PMCID: PMC3111338.
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Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids.

Clinical nutrition (Edinburgh, Scotland)

Gürdeniz G, Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Cloetens L, Herzig KH, Hukkanen J, Rosqvist F, Ulven SM, Gunnarsdóttir I, Thorsdottir I, Oresic M, Poutanen KS, Risérus U, Åkesson B, Dragsted LO.
PMID: 35007813
Clin Nutr. 2021 Dec 25;41(2):441-451. doi: 10.1016/j.clnu.2021.12.031. Epub 2021 Dec 25.

BACKGROUND & AIMS: Intake assessment in multicenter trials is challenging, yet important for accurate outcome evaluation. The present study aimed to characterize a multicenter randomized controlled trial with a healthy Nordic diet (HND) compared to a Control diet (CD)...

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Gürdeniz G, Uusitupa M, Hermansen K, et al. Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids. Clin Nutr. 2021;41(2):441-451doi: 10.1016/j.clnu.2021.12.031.
Gürdeniz, G., Uusitupa, M., Hermansen, K., Savolainen, M. J., Schwab, U., Kolehmainen, M., Brader, L., Cloetens, L., Herzig, K. H., Hukkanen, J., Rosqvist, F., Ulven, S. M., Gunnarsdóttir, I., Thorsdottir, I., Oresic, M., Poutanen, K. S., Risérus, U., Åkesson, B., & Dragsted, L. O. (2021). Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids. Clinical nutrition (Edinburgh, Scotland), 41(2), 441-451. https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, Gözde, et al. "Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids." Clinical nutrition (Edinburgh, Scotland) vol. 41,2 (2021): 441-451. doi: https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz G, Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Cloetens L, Herzig KH, Hukkanen J, Rosqvist F, Ulven SM, Gunnarsdóttir I, Thorsdottir I, Oresic M, Poutanen KS, Risérus U, Åkesson B, Dragsted LO. Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids. Clin Nutr. 2021 Dec 25;41(2):441-451. doi: 10.1016/j.clnu.2021.12.031. Epub 2021 Dec 25. PMID: 35007813.
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Role of Extracellular Vesicle-Derived Biomarkers in Drug Metabolism and Disposition.

Drug metabolism and disposition: the biological fate of chemicals

Useckaite Z, Rodrigues AD, Hopkins AM, Newman LA, Johnson J, Sorich MJ, Rowland A.
PMID: 34353847
Drug Metab Dispos. 2021 Nov;49(11):961-971. doi: 10.1124/dmd.121.000411. Epub 2021 Aug 05.

Extracellular vesicles (EVs) are small, nonreplicating, lipid-encapsulated particles that contain a myriad of protein and nucleic acid cargo derived from their tissue of origin. The potential role of EV-derived biomarkers to the study of drug metabolism and disposition (DMD)...

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Useckaite Z, Rodrigues AD, Hopkins AM, et al. Role of Extracellular Vesicle-Derived Biomarkers in Drug Metabolism and Disposition. Drug Metab Dispos. 2021;49(11):961-971doi: 10.1124/dmd.121.000411.
Useckaite, Z., Rodrigues, A. D., Hopkins, A. M., Newman, L. A., Johnson, J., Sorich, M. J., & Rowland, A. (2021). Role of Extracellular Vesicle-Derived Biomarkers in Drug Metabolism and Disposition. Drug metabolism and disposition: the biological fate of chemicals, 49(11), 961-971. https://doi.org/10.1124/dmd.121.000411
Useckaite, Zivile, et al. "Role of Extracellular Vesicle-Derived Biomarkers in Drug Metabolism and Disposition." Drug metabolism and disposition: the biological fate of chemicals vol. 49,11 (2021): 961-971. doi: https://doi.org/10.1124/dmd.121.000411
Useckaite Z, Rodrigues AD, Hopkins AM, Newman LA, Johnson J, Sorich MJ, Rowland A. Role of Extracellular Vesicle-Derived Biomarkers in Drug Metabolism and Disposition. Drug Metab Dispos. 2021 Nov;49(11):961-971. doi: 10.1124/dmd.121.000411. Epub 2021 Aug 05. PMID: 34353847.
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The Important Role of Endothelium and Extracellular Vesicles in the Cellular Mechanism of Aortic Aneurysm Formation.

International journal of molecular sciences

Mikołajczyk K, Spyt D, Zielińska W, Żuryń A, Faisal I, Qamar M, Świniarski P, Grzanka A, Gagat M.
PMID: 34884962
Int J Mol Sci. 2021 Dec 06;22(23). doi: 10.3390/ijms222313157.

Homeostasis is a fundamental property of biological systems consisting of the ability to maintain a dynamic balance of the environment of biochemical processes. The action of endogenous and exogenous factors can lead to internal balance disorder, which results in...

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Mikołajczyk K, Spyt D, Zielińska W, et al. The Important Role of Endothelium and Extracellular Vesicles in the Cellular Mechanism of Aortic Aneurysm Formation. Int J Mol Sci. 2021;22(23)doi: 10.3390/ijms222313157.
Mikołajczyk, K., Spyt, D., Zielińska, W., Żuryń, A., Faisal, I., Qamar, M., Świniarski, P., Grzanka, A., & Gagat, M. (2021). The Important Role of Endothelium and Extracellular Vesicles in the Cellular Mechanism of Aortic Aneurysm Formation. International journal of molecular sciences, 22(23), . https://doi.org/10.3390/ijms222313157
Mikołajczyk, Klaudia, et al. "The Important Role of Endothelium and Extracellular Vesicles in the Cellular Mechanism of Aortic Aneurysm Formation." International journal of molecular sciences vol. 22,23 (2021). doi: https://doi.org/10.3390/ijms222313157
Mikołajczyk K, Spyt D, Zielińska W, Żuryń A, Faisal I, Qamar M, Świniarski P, Grzanka A, Gagat M. The Important Role of Endothelium and Extracellular Vesicles in the Cellular Mechanism of Aortic Aneurysm Formation. Int J Mol Sci. 2021 Dec 06;22(23). doi: 10.3390/ijms222313157. PMID: 34884962; PMCID: PMC8658239.
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Inflammatory Mechanisms Contributing to Endothelial Dysfunction.

Biomedicines

Theofilis P, Sagris M, Oikonomou E, Antonopoulos AS, Siasos G, Tsioufis C, Tousoulis D.
PMID: 34356845
Biomedicines. 2021 Jul 06;9(7). doi: 10.3390/biomedicines9070781.

Maintenance of endothelial cell integrity is an important component of human health and disease since the endothelium can perform various functions including regulation of vascular tone, control of hemostasis and thrombosis, cellular adhesion, smooth muscle cell proliferation, and vascular...

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Theofilis P, Sagris M, Oikonomou E, et al. Inflammatory Mechanisms Contributing to Endothelial Dysfunction. Biomedicines. 2021;9(7)doi: 10.3390/biomedicines9070781.
Theofilis, P., Sagris, M., Oikonomou, E., Antonopoulos, A. S., Siasos, G., Tsioufis, C., & Tousoulis, D. (2021). Inflammatory Mechanisms Contributing to Endothelial Dysfunction. Biomedicines, 9(7), . https://doi.org/10.3390/biomedicines9070781
Theofilis, Panagiotis, et al. "Inflammatory Mechanisms Contributing to Endothelial Dysfunction." Biomedicines vol. 9,7 (2021). doi: https://doi.org/10.3390/biomedicines9070781
Theofilis P, Sagris M, Oikonomou E, Antonopoulos AS, Siasos G, Tsioufis C, Tousoulis D. Inflammatory Mechanisms Contributing to Endothelial Dysfunction. Biomedicines. 2021 Jul 06;9(7). doi: 10.3390/biomedicines9070781. PMID: 34356845; PMCID: PMC8301477.
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High-density lipoproteins and immune response: A review.

International journal of biological macromolecules

Grao-Cruces E, Lopez-Enriquez S, Martin ME, Montserrat-de la Paz S.
PMID: 34896462
Int J Biol Macromol. 2021 Dec 09;195:117-123. doi: 10.1016/j.ijbiomac.2021.12.009. Epub 2021 Dec 09.

High-density lipoproteins (HDLs) are heterogeneous lipoproteins that modify their composition and functionality depending on physiological or pathological conditions. The main roles of HDL are cholesterol efflux, and anti-inflammatory and antioxidant functions. These functions can be compromised under pathological conditions....

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Grao-Cruces E, Lopez-Enriquez S, Martin ME, et al. High-density lipoproteins and immune response: A review. Int J Biol Macromol. 2021;195:117-123doi: 10.1016/j.ijbiomac.2021.12.009.
Grao-Cruces, E., Lopez-Enriquez, S., Martin, M. E., & Montserrat-de la Paz, S. (2021). High-density lipoproteins and immune response: A review. International journal of biological macromolecules, 195117-123. https://doi.org/10.1016/j.ijbiomac.2021.12.009
Grao-Cruces, Elena, et al. "High-density lipoproteins and immune response: A review." International journal of biological macromolecules vol. 195 (2021): 117-123. doi: https://doi.org/10.1016/j.ijbiomac.2021.12.009
Grao-Cruces E, Lopez-Enriquez S, Martin ME, Montserrat-de la Paz S. High-density lipoproteins and immune response: A review. Int J Biol Macromol. 2021 Dec 09;195:117-123. doi: 10.1016/j.ijbiomac.2021.12.009. Epub 2021 Dec 09. PMID: 34896462.
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Associations of Body Mass Index and Waist Circumference in Young Adulthood with Later Life Incident Diabetes.

The Journal of clinical endocrinology and metabolism

Nair N, Vittinghoff E, Pletcher MJ, Oelsner EC, Allen NB, Ndumele CE, West NA, Strotmeyer ES, Mukamal KJ, Siscovick DS, Biggs ML, Laferrère B, Moran AE, Zhang Y.
PMID: 34302728
J Clin Endocrinol Metab. 2021 Nov 19;106(12):e5011-e5020. doi: 10.1210/clinem/dgab551.

CONTEXT: The independent contribution of young adult exposure to overweight and obesity to later-life incident diabetes is not well studied.OBJECTIVE: To assess the associations of exposures to elevated body mass index (BMI) and waist circumference (WC) in young adulthood...

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Nair N, Vittinghoff E, Pletcher MJ, et al. Associations of Body Mass Index and Waist Circumference in Young Adulthood with Later Life Incident Diabetes. J Clin Endocrinol Metab. 2021;106(12):e5011-e5020doi: 10.1210/clinem/dgab551.
Nair, N., Vittinghoff, E., Pletcher, M. J., Oelsner, E. C., Allen, N. B., Ndumele, C. E., West, N. A., Strotmeyer, E. S., Mukamal, K. J., Siscovick, D. S., Biggs, M. L., Laferrère, B., Moran, A. E., & Zhang, Y. (2021). Associations of Body Mass Index and Waist Circumference in Young Adulthood with Later Life Incident Diabetes. The Journal of clinical endocrinology and metabolism, 106(12), e5011-e5020. https://doi.org/10.1210/clinem/dgab551
Nair, Nandini, et al. "Associations of Body Mass Index and Waist Circumference in Young Adulthood with Later Life Incident Diabetes." The Journal of clinical endocrinology and metabolism vol. 106,12 (2021): e5011-e5020. doi: https://doi.org/10.1210/clinem/dgab551
Nair N, Vittinghoff E, Pletcher MJ, Oelsner EC, Allen NB, Ndumele CE, West NA, Strotmeyer ES, Mukamal KJ, Siscovick DS, Biggs ML, Laferrère B, Moran AE, Zhang Y. Associations of Body Mass Index and Waist Circumference in Young Adulthood with Later Life Incident Diabetes. J Clin Endocrinol Metab. 2021 Nov 19;106(12):e5011-e5020. doi: 10.1210/clinem/dgab551. PMID: 34302728.
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Integrated Pipeline of Rapid Isolation and Analysis of Human Plasma Exosomes for Cancer Discrimination Based on Deep Learning of MALDI-TOF MS Fingerprints.

Analytical chemistry

Zheng H, Zhao J, Wang X, Yan S, Chu H, Gao M, Zhang X.
PMID: 35025210
Anal Chem. 2022 Jan 13; doi: 10.1021/acs.analchem.1c04762. Epub 2022 Jan 13.

Plasma exosomes have shown great potential for liquid biopsy in clinical cancer diagnosis. Herein, we present an integrated strategy for isolating and analyzing exosomes from human plasma rapidly and then discriminating different cancers excellently based on deep learning fingerprints...

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Zheng H, Zhao J, Wang X, et al. Integrated Pipeline of Rapid Isolation and Analysis of Human Plasma Exosomes for Cancer Discrimination Based on Deep Learning of MALDI-TOF MS Fingerprints. Anal Chem. 2022;doi: 10.1021/acs.analchem.1c04762.
Zheng, H., Zhao, J., Wang, X., Yan, S., Chu, H., Gao, M., & Zhang, X. (2022). Integrated Pipeline of Rapid Isolation and Analysis of Human Plasma Exosomes for Cancer Discrimination Based on Deep Learning of MALDI-TOF MS Fingerprints. Analytical chemistry, . https://doi.org/10.1021/acs.analchem.1c04762
Zheng, Haoyang, et al. "Integrated Pipeline of Rapid Isolation and Analysis of Human Plasma Exosomes for Cancer Discrimination Based on Deep Learning of MALDI-TOF MS Fingerprints." Analytical chemistry vol. (2022). doi: https://doi.org/10.1021/acs.analchem.1c04762
Zheng H, Zhao J, Wang X, Yan S, Chu H, Gao M, Zhang X. Integrated Pipeline of Rapid Isolation and Analysis of Human Plasma Exosomes for Cancer Discrimination Based on Deep Learning of MALDI-TOF MS Fingerprints. Anal Chem. 2022 Jan 13; doi: 10.1021/acs.analchem.1c04762. Epub 2022 Jan 13. PMID: 35025210.
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Cell-to-Cell Transfer of Bacterial Lipoproteins.

[No authors listed]
UIID-NSF: 439

Intellectual Merit Myxobacteria rely on cell-cell signaling and gliding motility to live as multicellular organisms that build fruiting body structures in response to starvation. How cell-cell signaling organizes these developmental processes remains a fundamental biological question. To help understand...

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Cell-to-Cell Transfer of Bacterial Lipoproteins. ;
(). Cell-to-Cell Transfer of Bacterial Lipoproteins. .
"Cell-to-Cell Transfer of Bacterial Lipoproteins." vol. ().
Cell-to-Cell Transfer of Bacterial Lipoproteins. UIID-NSF: 439.
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Showing 2449 to 2458 of 2458 entries