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Showing 445 to 455 of 455 entries
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Subcutaneous etonogestrel implant combined with endometrial ablation for the treatment of adenomyosis: two case reports.

The journal of obstetrics and gynaecology research

Nie LK, Zou HL, Cheng L, Zhang PH.
PMID: 34713941
J Obstet Gynaecol Res. 2022 Jan;48(1):262-265. doi: 10.1111/jog.15084. Epub 2021 Oct 29.

Adenomyosis is a common disease that affects many premenopausal women. Two patients with adenomyosis, aged 51 and 42 years, presented with dysmenorrhea and increased menstrual volume. They refused laparoscopy or laparotomy surgery and were not eligible for the levonorgestrel-releasing...

Models and methods to characterise levonorgestrel release from intradermally administered contraceptives.

Drug delivery and translational research

Al Dalaty A, Gualeni B, Coulman SA, Birchall JC.
PMID: 34862590
Drug Deliv Transl Res. 2021 Dec 03; doi: 10.1007/s13346-021-01091-5. Epub 2021 Dec 03.

Microneedle (MN)-based technologies have been proposed as a means to facilitate minimally invasive sustained delivery of long-acting hormonal contraceptives into the skin. Intradermal administration is a new route of delivery for these contraceptives and therefore no established laboratory methods...

Ectopic Pregnancy in a Levonogestrel-Releasing Intrauterine Device User: A Case Report.

Cureus

Resta C, Dooley WM, Malligiannis Ntalianis K, Burugapalli S, Hussain M.
PMID: 34804718
Cureus. 2021 Oct 18;13(10):e18867. doi: 10.7759/cureus.18867. eCollection 2021 Oct.

Levonorgestrel-releasing intrauterine devices are considered to be a reliable contraceptive option with a low failure rate. The risk of ectopic pregnancy, however, if an unintended pregnancy occurs is significantly higher. In this study, we present a case of a...

Reasons reported by women for choosing the levonorgestrel intrauterine system as a contraceptive method.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Laporte M, Charles CM, Metelus S, Peloggia A, de O Paez G, Juliato CT, Bahamondes L.
PMID: 34862968
Int J Gynaecol Obstet. 2021 Dec 04; doi: 10.1002/ijgo.14062. Epub 2021 Dec 04.

OBJECTIVES: To assess the reasons provided by women for choosing the use of the 52mg levonorgestrel intrauterine system (LNG-IUS) as a contraceptive method.MATERIALS AND METHODS: We conducted a cross sectional study from January 2021 to August 2021 at the...

Clinical efficacy of levonorgestrel intrauterine system (Mirena) combined with hysteroscopy in the treatment of perimenopausal AUB patients.

Pakistan journal of pharmaceutical sciences

Sun Y, Qian M, Hu D.
PMID: 34862877
Pak J Pharm Sci. 2021 Sep;34(5):2079-2083.

Perimenopausal abnormal uterine bleeding (AUB) is most common in ovulation dysfunction, which seriously compromises patients' health. This study aims to evaluate the efficacy of levonorgestrel intrauterine system (Mirena) plus hysteroscopy respectively in perimenopausal AUB. Sixty perimenopausal AUB patients treated...

Combined estrogen-progestogen but not progestogen-only oral contraceptive alters glucose tolerance and plasma lipid profile in female rats.

Pathophysiology : the official journal of the International Society for Pathophysiology

Olatunji LA, Michael OS, Adewumi FO, Aiyegboyin IJ, Olatunji VA.
PMID: 21943687
Pathophysiology. 2012 Feb;19(1):29-34. doi: 10.1016/j.pathophys.2011.09.001. Epub 2011 Sep 22.

Women are exposed to sex steroids in several formulations such as oral contraceptives (OCs) and hormone replacement therapies. Estrogen is believed to have cardiometabolic protection effect; but its beneficial effects have recently been queried. The aim of the present...

Impact of polymer crosslinking on release mechanisms from long-acting levonorgestrel intrauterine systems.

International journal of pharmaceutics

Fanse S, Bao Q, Zou Y, Wang Y, Burgess DJ.
PMID: 34919997
Int J Pharm. 2022 Jan 25;612:121383. doi: 10.1016/j.ijpharm.2021.121383. Epub 2021 Dec 14.

Polydimethylsiloxane (PDMS) crosslinking density is a critical material attribute of levonorgestrel intrauterine systems (LNG-IUSs) that affects drug release and may have a significant influence on product performance and safety. Accordingly, the objective of the present work was to investigate...

Models and methods to characterise levonorgestrel release from intradermally administered contraceptives.

Drug delivery and translational research

Al Dalaty A, Gualeni B, Coulman SA, Birchall JC.
PMID: 34862590
Drug Deliv Transl Res. 2022 Feb;12(2):335-349. doi: 10.1007/s13346-021-01091-5. Epub 2021 Dec 03.

Microneedle (MN)-based technologies have been proposed as a means to facilitate minimally invasive sustained delivery of long-acting hormonal contraceptives into the skin. Intradermal administration is a new route of delivery for these contraceptives and therefore no established laboratory methods...

Long-term safety of extended levonorgestrel-containing oral contraceptives in the United States.

Contraception

Kaplan S, Bertoia ML, Wang FT, Zhou L, Lass A, Evans A, Dhanda S, Roy D, Seeger JD.
PMID: 34599911
Contraception. 2022 Jan;105:26-32. doi: 10.1016/j.contraception.2021.09.013. Epub 2021 Sep 30.

OBJECTIVES: To compare the safety profile of Seasonique, a 91-day levonorgestrel-containing combined oral contraceptive (COCSTUDY DESIGN: A new user cohort study was conducted in a US health care database from 2006 to 2017. Each 91-day COCRESULTS: Of the 25,593...

Weight change among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception did not influence early discontinuation.

EClinicalMedicine

Bahamondes L.
PMID: 33912819
EClinicalMedicine. 2021 Apr 14;34:100857. doi: 10.1016/j.eclinm.2021.100857. eCollection 2021 Apr.

No abstract available.

Use of the Levonorgestrel Intrauterine System to Treat Heavy Menstrual Bleeding in Adolescents and Young Adults with Inherited Bleeding Disorders and Ehlers-Danlos Syndrome.

Journal of pediatric and adolescent gynecology

Huguelet PS, Laurin JL, Thornhill D, Moyer G.
PMID: 34775059
J Pediatr Adolesc Gynecol. 2021 Nov 11; doi: 10.1016/j.jpag.2021.11.002. Epub 2021 Nov 11.

STUDY OBJECTIVE: To report on the rate of amenorrhea among adolescents and young adults with a bleeding diathesis after insertion of the 52-mg levonorgestrel intrauterine system (LNG-IUS) DESIGN: Retrospective chart review SETTING: Tertiary care, multidisciplinary Gynecology-Hematology clinic or Adolescent...

Showing 445 to 455 of 455 entries