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Showing 1885 to 1893 of 1893 entries
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LIMS1 risk genotype and T cell-mediated rejection in kidney transplant recipients.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Caliskan Y, Karahan G, Akgul SU, Mirioglu S, Ozluk Y, Yazici H, Demir E, Dirim AB, Turkmen A, Edwards J, Savran FO, Sever MS, Kiryluk K, Gharavi A, Lentine KL.
PMID: 33909908
Nephrol Dial Transplant. 2021 Nov 09;36(11):2120-2129. doi: 10.1093/ndt/gfab168.

BACKGROUND: This study aims to examine the association of LIM zinc finger domain containing 1 (LIMS1) genotype with allograft rejection in an independent kidney transplant cohort.METHODS: We genotyped 841 kidney transplant recipients for the LIMS1 rs893403 variant by Sanger...

Acute epiglottitis in a COVID-19 positive patient.

The American journal of emergency medicine

Cordial P, Le T, Neuenschwander J.
PMID: 34294502
Am J Emerg Med. 2022 Jan;51:427.e1-427.e2. doi: 10.1016/j.ajem.2021.06.077. Epub 2021 Jul 07.

There have been more than 178 million global cases of COVID-19, the disease caused by the SARS-CoV-2 virus, with more than 3.8 million deaths worldwide [1]. COVID-19 can present with a wide variety of symptoms, and one rare manifestation...

Associations of Sex Hormones and Hormonal Status With Arterial Stiffness in a Female Sample From Reproductive Years to Menopause.

Frontiers in endocrinology

Laakkonen EK, Karppinen JE, Lehti S, Lee E, Pesonen E, Juppi HK, Kujala UM, Haapala EA, Aukee P, Laukkanen JA, Ihalainen JK.
PMID: 34917027
Front Endocrinol (Lausanne). 2021 Nov 30;12:765916. doi: 10.3389/fendo.2021.765916. eCollection 2021.

OBJECTIVE: Loss of sex hormones has been suggested to underlie menopause-associated increment in cardiovascular risk. We investigated associations of sex hormones with arterial stiffness in 19-58-years-old women. We also studied associations of specific hormonal stages, including natural menstrual cycle,...

A review on the antimicrobial properties of lectins.

International journal of biological macromolecules

Fonseca VJA, Braga AL, Filho JR, Teixeira CS, da Hora GCA, Morais-Braga MFB.
PMID: 34896466
Int J Biol Macromol. 2021 Dec 09;195:163-178. doi: 10.1016/j.ijbiomac.2021.11.209. Epub 2021 Dec 09.

Lectins are biologically versatile biomolecules with remarkable antimicrobial effects, notably against bacteria, fungi and protozoa, in addition to modulating host immunity. For this, the lectins bind to carbohydrates on the surface of the pathogen, which can cause damage to...

Show your true color: Mammalian cell surface staining for tracking cellular identity in multiplexing and beyond.

Current opinion in chemical biology

Hassdenteufel S, Schuldiner M.
PMID: 34861482
Curr Opin Chem Biol. 2021 Nov 30;66:102102. doi: 10.1016/j.cbpa.2021.102102. Epub 2021 Nov 30.

Fluorescence microscopy revolutionized cell biology and changed requirements for dyes towards higher brightness, novel capacities, and specific targets. With the need for multiplexing assays in high-throughput methodologies, surface staining gained particular interest because it allows rapid application of exogenous...

CAN DOMESTICATION SHAPE CANIDAE BRAIN MORPHOLOGY? THE ACCESSORY OLFACTORY BULB OF THE RED FOX AS A CASE IN POINT.

Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft

Ortiz-Leal I, Torres MV, Villamayor PR, Fidalgo LE, López-Beceiro A, Sanchez-Quinteiro P.
PMID: 34896556
Ann Anat. 2021 Dec 09;151881. doi: 10.1016/j.aanat.2021.151881. Epub 2021 Dec 09.

BACKGROUND: The accessory olfactory bulb (AOB) is the first integrative center of the vomeronasal system (VNS), and the general macroscopic, microscopic, and neurochemical organizational patterns of the AOB differ fundamentally among species. Therefore, the low degree of differentiation observed...

The Linkage Phase of the Polymorphism KCNH2-K897T Influences the Electrophysiological Phenotype in hiPSC Models of LQT2.

Frontiers in physiology

van den Brink L, Brandão KO, Yiangou L, Blanch-Asensio A, Mol MPH, Mummery CL, Verkerk AO, Davis RP.
PMID: 34992545
Front Physiol. 2021 Dec 16;12:755642. doi: 10.3389/fphys.2021.755642. eCollection 2021.

While rare mutations in ion channel genes are primarily responsible for inherited cardiac arrhythmias, common genetic variants are also an important contributor to the clinical heterogeneity observed among mutation carriers. The common single nucleotide polymorphism (SNP) KCNH2-K897T is associated...

Operational challenges in the COVID-19 era: Asymptomatic infections and vaccination timing.

Clinical transplantation

Axelrod DA, Ince D, Harhay MN, Mannon RB, Alhamad T, Cooper M, Josephson MA, Caliskan Y, Sharfuddin A, Kumar V, Guenette A, Schnitzler MA, Ainapurapu S, Lentine KL.
PMID: 34297878
Clin Transplant. 2021 Nov;35(11):e14437. doi: 10.1111/ctr.14437. Epub 2021 Nov 02.

The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented challenges for solid organ transplant programs. While transplant activity has largely recovered, appropriate management of deceased donor candidates who are asymptomatic but have positive nucleic acid testing (NAT) for SARS-CoV-2...

Integrated analysis of glycan and RNA in single cells.

iScience

Minoshima F, Ozaki H, Odaka H, Tateno H.
PMID: 34401666
iScience. 2021 Jul 17;24(8):102882. doi: 10.1016/j.isci.2021.102882. eCollection 2021 Aug 20.

Single-cell sequencing has emerged as an indispensable technology to dissect cellular heterogeneity but never been applied to the simultaneous analysis of glycan and RNA. Using oligonucleotide-labeled lectins, we first established lectin-based glycan profiling of single cells by sequencing (scGlycan-seq)....

Showing 1885 to 1893 of 1893 entries