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Showing 25 to 32 of 32 entries
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Detection of salinomycin and lasalocid in chicken liver by icELISA based on functional bispecific single-chain antibody (scDb) and interpretation of molecular recognition mechanism.

Analytical and bioanalytical chemistry

Chen Y, Zhao K, Huang J, Li M, Sun X, Li J.
PMID: 34661725
Anal Bioanal Chem. 2021 Nov;413(28):7031-7041. doi: 10.1007/s00216-021-03666-0. Epub 2021 Oct 18.

Salinomycin (SAL) and lasalocid (LAS) are widely used as ionophore antibiotics for coccidiosis control. However, their common use as feed additives has led to the occurrence of feed cross-contamination, which has toxic effects on non-target animals. There have been...

Isolation and characterization of a novel thermophilic, freshwater methanogen.

Applied and environmental microbiology

Harris JE, Pinn PA, Davis RP.
PMID: 16346676
Appl Environ Microbiol. 1984 Dec;48(6):1123-8. doi: 10.1128/aem.48.6.1123-1128.1984.

A novel thermophilic, coccoid methanogen isolated from nonthermal freshwater sediments is described. Hydrogen plus carbon dioxide and formate were substrates for methanogenesis, and methane production was stimulated by yeast extract, Casamino Acids, and tryptose. Growth also occurred autotrophically. Elevated...

Analysis of Multidrug Transporter in Living Cells. Inhibition of P-glycoprotein-mediated Efflux of Anthracyclines by Ionophores.

Metal-based drugs

Borrel MN, Pereira E, Fiallo M, Garnier-Suillerot A.
PMID: 18476229
Met Based Drugs. 1994;1(2):175-82. doi: 10.1155/MBD.1994.175.

One of the major obstacles of chemotherapy is that, after repeated treatments, cellular resistance to the drug appears. The problem is that the tumor cells become resistant not only to the drugs which have been used during the treatment...

Determination of lasalocid with sensitized terbium(III) luminescence detection.

Talanta

Aguilar-Caballos MP, Gómez-Hens A, Pérez-Bendito D.
PMID: 18967460
Talanta. 1999 Jan;48(1):209-17. doi: 10.1016/s0039-9140(98)00240-9.

The luminescence of the lasalocid-terbium(III) system in the presence of Triton X-100 and trioctylphosphine oxide has been studied by obtaining kinetic and equilibrium measurements and using the stopped-flow mixing technique. The initial rate and luminescence signal of this system...

Biogenic amine-ionophore interactions: Structure and dynamics of lasalocid (X537A) complexes with phenethylamines and catecholamines in nonpolar solution.

Proceedings of the National Academy of Sciences of the United States of America

Shen C, Patel DJ.
PMID: 16592462
Proc Natl Acad Sci U S A. 1977 Nov;74(11):4734-8. doi: 10.1073/pnas.74.11.4734.

The ionophore lasalocid A forms 1:1 complexes with phenethylamines (1-amino-1-phenylethane and 1-amino-2-phenylethane) and catecholamines (dopamine and norepinephrine) in nonpolar solution. We have undertaken high-resolution proton nuclear magnetic resonance studies to deduce structural and kinetic information on the ionophore-biogenic amine...

Clinical and pathological changes caused by the interaction of lasalocid and chloramphenicol in broiler chickens.

Avian pathology : journal of the W.V.P.A

Perelman B, Abarbanel JM, Gur-Lavie A, Meller Y, Elad T.
PMID: 18766527
Avian Pathol. 1986;15(2):279-88. doi: 10.1080/03079458608436288.

Uncommon and abnormal gait, characterised by toe walking and progressive leg weakness, was observed in a large broiler flock in Israel. Identical clinical signs were reproduced when young chicks received feed supplemented with lasalocid (Abatec-Roche), and chloramphenicol at normal...

The ion selectivity of nonelectrogenic ionophores measured on a bilayer lipid membrane: nigericin, monensin, A23187 and lasalocid A.

Biochimica et biophysica acta

Antonenko YN, Yaguzhinsky LS.
PMID: 19927398
Biochim Biophys Acta. 1988 Feb 18;938(2):125-30. doi: 10.1016/0005-2736(88)90151-4.

A new method for measuring ion selectivity of nonelectrogenic ionophores on a planar bilayer lipid membrane (BLM) has been developed. This method is based on the phenomenon of formation of local gradients of ion concentration arising in the unstirred...

Selective and synergistic cobalt(III)-catalyzed three-component C-H bond addition to dienes and aldehydes.

Nature catalysis

Boerth JA, Maity S, Williams SK, Mercado BQ, Ellman JA.
PMID: 30221249
Nat Catal. 2018;1:673-679. doi: 10.1038/s41929-018-0123-4.

Two-component C-H bond additions to a large variety of coupling partners have been developed with applications towards materials, natural product and drug synthesis. Sequential three-component C-H bond addition across two different coupling partners potentially enables the convergent synthesis of...

Showing 25 to 32 of 32 entries