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Showing 13 to 24 of 107 entries
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Buprenorphine Analgesia Reduces Survival With ALM Resuscitation in a Rat Model of Uncontrolled Hemorrhage: Concerns for Trauma-Related Research.

Shock (Augusta, Ga.)

Letson HL, Dobson GP.
PMID: 32925604
Shock. 2021 Mar 01;55(3):379-387. doi: 10.1097/SHK.0000000000001630.

ABSTRACT: The effect of analgesia on physiological systems has received little attention in trauma research. Our aim was to examine the effect of two different analgesics, buprenorphine and carprofen, on adenosine, lidocaine, and magnesium (ALM) resuscitation in a rat...

Role of TRPV4 Channel in Human White Adipocytes Metabolic Activity.

Endocrinology and metabolism (Seoul, Korea)

Sánchez JC, Valencia-Vásquez A, García AM.
PMID: 34648704
Endocrinol Metab (Seoul). 2021 Oct;36(5):997-1006. doi: 10.3803/EnM.2021.1167. Epub 2021 Oct 14.

BACKGROUND: Intracellular calcium (Ca2+) homeostasis plays an essential role in adipocyte metabolism and its alteration is associated with obesity and related disorders. Transient receptor potential vanilloid 4 (TRPV4) channels are an important Ca2+ pathway in adipocytes and their activity...

The handheld blood lactate analyser versus the blood gas based analyser for measurement of serum lactate and its prognostic significance in severe sepsis.

Medical journal, Armed Forces India

Singh S, Bhardawaj A, Shukla R, Jhadav T, Sharma A, Basannar D.
PMID: 27843178
Med J Armed Forces India. 2016 Oct;72(4):325-331. doi: 10.1016/j.mjafi.2016.05.007. Epub 2016 Jul 26.

BACKGROUND: This study was done to compare the accuracy of the Lactate Pro LT 1710 (Arkray Inc., Kyoto, Japan) with the Combiline Plus (Eschweiler GmbH & Co. KG Holzkoppelweg, Kiel, Germany), and also, to analyze the prognostic significance of...

Effect of Wearing Surgical Face Masks During Exercise: Does Intensity Matter?.

Frontiers in physiology

Poon ET, Zheng C, Wong SH.
PMID: 34899397
Front Physiol. 2021 Nov 26;12:775750. doi: 10.3389/fphys.2021.775750. eCollection 2021.

Face masks are widely recommended as means of controlling the coronavirus disease outbreak. This study aimed to examine the physiological and perceptual responses of wearing surgical face masks while exercising at different intensities. Thirteen healthy young adults (mean age,...

Chiral aggregates and asymmetric induction of the reduction of prochiral ketones.

Chirality

Rico-Lattes I, Schmitzer A, Perez E, Lattes A.
PMID: 11135410
Chirality. 2001;13(1):24-28. doi: 10.1002/1520-636X(2001)13:1<24::AID-CHIR5>3.0.CO;2-X.

The aim of this work was to establish structure-reactivity relationships between chiral aggregates (micelles, vesicles, and "pseudo-micelles" of amphiphilic dendrimers) and asymmetric induction. In water, micelles or vesicles formed with sugar-headed surfactants gave less than 10% ee in the...

[In memory of Arthur Purdy Stout].

Il Cancro

Lattes R.
PMID: 4909807
Cancro. 1967;20(6):846-7.

No abstract available.

Reactivity at the interface of chiral amphiphilic dendrimers. High asymmetric reduction by NaBH(4) of various prochiral ketones.

Journal of the American Chemical Society

Schmitzer AR, Franceschi S, Perez E, Rico-Lattes I, Lattes A, Thion L, Erard M, Vidal C.
PMID: 11414829
J Am Chem Soc. 2001 Jun 27;123(25):5956-61. doi: 10.1021/ja000378x.

New amphiphilic dendrimers derived from PAMAM and D-gluconolactone were found to induce chirality in the reduction of prochiral ketones by NaBH(4), in heterogeneous (THF) and homogeneous (water) conditions. The third generation of these amphiphilic dendrimers, G(3)G, was found to...

Aggregation Behavior in Aqueous Solutions of a New Class of Asymmetric Bipolar Amphiphiles Investigated by Surface Tension Measurements.

Journal of colloid and interface science

Gouzy MF, Guidetti B, André-Barres C, Rico-Lattes I, Lattes A, Vidal C.
PMID: 11427018
J Colloid Interface Sci. 2001 Jul 15;239(2):517-521. doi: 10.1006/jcis.2001.7589.

Two series of amphiphilic derivatives of lactose have been synthesized. Tensiometric investigations of the critical micellar concentration (CMC) and the area per molecule at interface (calculated by the Gibbs equation) of aqueous solutions were performed. The values measured depend...

Lipid-based Nanosized Delivery Systems for Fluoroquinolones: a Review.

Current pharmaceutical design

Furneri PM, Fuochi V, Pignatello R.
PMID: 29173152
Curr Pharm Des. 2017 Nov 21; doi: 10.2174/1381612823666171122110103. Epub 2017 Nov 21.

BACKGROUND: The class of fluoroquinolone antibiotics, due to its core chemical modifications, is considered as wide-spectrum antibacterial drugs with useful pharmacokinetic and pharmacodynamic properties. However, because of their poor solubility in water, they are used as salts (lactates or...

ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.

Neuron

López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, Swing D, Qiu J, Hicks GG, Ouyang Z, Fu XD, Tessarollo L, Ling SC, Parone PA, Shaw CE, Marsala M, Lagier-Tourenne C, Cleveland DW, Da Cruz S.
PMID: 32325059
Neuron. 2020 Apr 22;106(2):354. doi: 10.1016/j.neuron.2020.04.006.

No abstract available.

Diabetes and Sepsis: Risk, Recurrence, and Ruination.

Frontiers in endocrinology

Frydrych LM, Fattahi F, He K, Ward PA, Delano MJ.
PMID: 29163354
Front Endocrinol (Lausanne). 2017 Oct 30;8:271. doi: 10.3389/fendo.2017.00271. eCollection 2017.

Sepsis develops when an infection surpasses local tissue containment. A series of dysregulated physiological responses are generated, leading to organ dysfunction and a 10% mortality risk. When patients with sepsis demonstrate elevated serum lactates and require vasopressor therapy to...

A suite-level review of the neutron single-crystal diffraction instruments at Oak Ridge National Laboratory.

The Review of scientific instruments

Coates L, Cao HB, Chakoumakos BC, Frontzek MD, Hoffmann C, Kovalevsky AY, Liu Y, Meilleur F, Dos Santos AM, Myles DAA, Wang XP, Ye F.
PMID: 30278686
Rev Sci Instrum. 2018 Sep;89(9):092802. doi: 10.1063/1.5030896.

The nascent suite of single-crystal neutron diffractometers at the Oak Ridge National Laboratory has no equal at any other neutron scattering facility worldwide and offers the potential to re-assert single-crystal diffraction using neutrons as a significant tool to study...

Showing 13 to 24 of 107 entries