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Showing 13 to 24 of 83 entries
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Relief of vasospasm with fasudil after off-pump coronary artery bypass grafting: a case study.

Surgical case reports

Fujita A, Kurazumi H, Suzuki R, Takahashi M, Mikamo A, Hamano K.
PMID: 30051150
Surg Case Rep. 2018 Jul 27;4(1):82. doi: 10.1186/s40792-018-0481-9.

BACKGROUND: Coronary vasospasm after coronary artery bypass grafting (CABG) is a rare but potentially lethal complication. It is often refractory to several vasodilators. We report a case of refractory coronary vasospasm relieved by fasudil injection.CASE PRESENTATION: A 74-year-old woman...

Comparison of vaginal misoprostol, laminaria, and isosorbide dinitrate on cervical preparation and labor duration of term parturient: a randomized double-blind clinical trial.

Electronic physician

Souizi B, Mortazavi F, Haeri S, Borzoee F.
PMID: 29997758
Electron Physician. 2018 May 05;10(5):6756-6763. doi: 10.19082/6756. eCollection 2018 May.

BACKGROUND: Cervical ripening plays an important role in successful labor induction.OBJECTIVE: This study aimed to compare the effects of misoprostol, laminaria tent, and isosorbide dinitrate (ISDN) on cervical ripening.METHODS: This double-blind three-armed clinical trial was conducted at Shahidan Mombini...

Metabolomic profiles of myocardial ischemia under treatment with salvianolic acid B.

Chinese medicine

Lu Y, Zheng Y, Liu X, Liang X, Ngai S, Li T, Zhang W.
PMID: 22409910
Chin Med. 2012 Mar 13;7(1):6. doi: 10.1186/1749-8546-7-6.

BACKGROUND: Radix Salvia miltiorrhiza (Danshen) has been used as a principal herb in treating cardiovascular diseases in Chinese medicine. Salvianolic acid B (SA-B), a water-soluble active component of Danshen, was found to have anti-myocardial ischemia (anti-MI) effect. This study...

Conservative treatments for acute nonarteritic central retinal artery occlusion: Do they work?.

Taiwan journal of ophthalmology

Sharma RA, Newman NJ, Biousse V.
PMID: 33767952
Taiwan J Ophthalmol. 2020 Nov 06;11(1):16-24. doi: 10.4103/tjo.tjo_61_20. eCollection 2021.

Acute central retinal arterial occlusion has a very poor visual prognosis. Unfortunately, there is a dearth of evidence to support the use of any of the so-called "conservative" treatment options for CRAO, and the use of thrombolytics remains controversial....

Search for Therapeutic Agents for Cardiac Arrest Using a Drug Discovery Tool and Large-Scale Medical Information Database.

Frontiers in pharmacology

Zamami Y, Niimura T, Koyama T, Shigemi Y, Izawa-Ishizawa Y, Morita M, Ohshima A, Harada K, Imai T, Hagiwara H, Okada N, Goda M, Takechi K, Chuma M, Kondo Y, Tsuchiya K, Hinotsu S, Kano MR, Ishizawa K.
PMID: 31780928
Front Pharmacol. 2019 Nov 08;10:1257. doi: 10.3389/fphar.2019.01257. eCollection 2019.

The survival rate of cardiac arrest patients is less than 10%; therefore, development of a therapeutic strategy that improves their prognosis is necessary. Herein, we searched data collected from medical facilities throughout Japan for drugs that improve the survival...

Naproxen, isosorbide dinitrate and co-administration cannot prevent post-endoscopic retrograde cholangiopancreatography pancreatitis: Randomized controlled trial.

Annals of hepato-biliary-pancreatic surgery

Mansour-Ghanaei F, Joukar F, Khalesi AA, Naghipour M, Sepehrimanesh M, Mojtahedi K, Yeganeh S, Saedi HS, Asl SF.
PMID: 32843590
Ann Hepatobiliary Pancreat Surg. 2020 Aug 31;24(3):259-268. doi: 10.14701/ahbps.2020.24.3.259.

BACKGROUNDS/AIMS: Acute pancreatitis is the most widespread complication of endoscopic retrograde cholangiopancreatography. Here, we investigated the efficacy of rectal suppository naproxen, sublingual isosorbide dinitrate and their co-administration in the prevention of post-ERCP pancreatitis.METHODS: This double-blind randomized clinical trial carried...

Preclusion of methemoglobinemia caused by nitrate drugs in diabetics and nondiabetics: Possible role of Vitamin C.

Blood cells, molecules & diseases

Das D, Sen S, Bhakta S, Sen K.
PMID: 35033940
Blood Cells Mol Dis. 2022 Jan 05;94:102643. doi: 10.1016/j.bcmd.2021.102643. Epub 2022 Jan 05.

The drugs containing nitrates like isosorbide dinitrate, isosorbide mononitrate and glyceryl trinitrate, etc., trigger the oxidation of hemoglobin which is manifested in the pathological disorder named methemoglobinemia. It was considered interesting to investigate the preventive roles of vitamin C...

Physiological Impact of Afterload Reduction on Cardiac Mechanics and Coronary Hemodynamics Following Isosorbide Dinitrate Administration in Ischemic Heart Disease.

Journal of cardiovascular translational research

Patterson T, Rivolo S, Burkhoff D, Schreuder J, Briceno N, Allen C, Williams R, Arri S, Asrress KN, Joseph J, McConkey HZR, Ellis H, Pavlidis A, Clapp B, Perera D, Lee J, Marber MS, Redwood SR.
PMID: 33721195
J Cardiovasc Transl Res. 2021 Oct;14(5):962-974. doi: 10.1007/s12265-021-10112-0. Epub 2021 Mar 15.

Understanding the cardiac-coronary interaction is fundamental to developing treatment strategies for ischemic heart disease. We sought to examine the impact of afterload reduction following isosorbide dinitrate (ISDN) administration on LV properties and coronary hemodynamics to further our understanding of...

Injection of botulinum toxin significantly increases efficiency of fissurectomy in the treatment of chronic anal fissures.

International journal of colorectal disease

Roelandt P, Coremans G, Wyndaele J.
PMID: 34727216
Int J Colorectal Dis. 2021 Nov 02; doi: 10.1007/s00384-021-04057-8. Epub 2021 Nov 02.

PURPOSE: While acute anal fissures can be treated with topical therapy to reduce sphincter hypertonia (e.g., isosorbide dinitrate, glyceryl trinitrate, diltiazem), chronic fissures may require more invasive instrumental therapy. Currently, the golden standard remains lateral internal sphincterotomy; however, this...

Omecamtiv Mecarbil: A Novel Mechanistic and Therapeutic Approach to Chronic Heart Failure Management.

Cureus

Patel PH, Nguyen M, Rodriguez R, Surani S, Udeani G.
PMID: 33542867
Cureus. 2021 Jan 01;13(1):e12419. doi: 10.7759/cureus.12419.

Heart failure (HF) is a major public health problem in the United States as well as worldwide. Chronic heart failure is a syndrome of reduced cardiac output resulting from impaired ventricular function, impaired filling, or a combination of both....

Effects of propranolol and nitrates on exercise capacity, respiratory minute volume and capillary oxygen saturation during exercise in cirrhotic patients with portal hypertension.

Hepatology research : the official journal of the Japan Society of Hepatology

Premaratna R, Sathishchandra H, Thilakaratna Y, Shantharaj W, de Silva H.
PMID: 12270744
Hepatol Res. 2002 Oct;24(2):152. doi: 10.1016/s1386-6346(02)00079-7.

A cross over study was performed in 16 cirrhotic patients with portal hypertension and oesophageal varices to assess the effects of propranolol and nitrates on the exercise capacity, respiratory minute volume and capillary oxygen saturation during exercise. All had...

A Multicenter, Prospective, Randomized Controlled Trial Evaluating the Efficacy of Rectal Diclofenac and Sublingual Nitrate as a Combined Prophylactic Treatment for Post-ERCP Pancreatitis.

Acta medica Okayama

Tomoda T, Kato H, Mizukawa S, Muro S, Akimoto Y, Uchida D, Matsumoto K, Yamamoto N, Horiguchi S, Tsutsumi K, Okada H.
PMID: 28824193
Acta Med Okayama. 2017 Aug;71(4):357-362. doi: 10.18926/AMO/55314.

Acute pancreatitis is the major complication of endoscopic retrograde cholangiopancreatography(ERCP). A preliminary research suggested that the administration of nonsteroidal anti-inflammatory drugs (NSAIDs) with nitrate might reduce the incidence of post-ERCP pancreatitis (PEP) more effectively than NSAIDs alone. We conduct...

Showing 13 to 24 of 83 entries