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Showing 997 to 1007 of 1007 entries
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Dynamic Monitoring of Systemic Biomarkers with Gastric Sensors.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Steiger C, Phan NV, Huang HW, Sun H, Chu JN, Reker D, Gwynne D, Collins J, Tamang S, McManus R, Lopes A, Hayward A, Baron RM, Kim EY, Traverso G.
PMID: 34713599
Adv Sci (Weinh). 2021 Dec;8(24):e2102861. doi: 10.1002/advs.202102861. Epub 2021 Oct 28.

Continuous monitoring in the intensive care setting has transformed the capacity to rapidly respond with interventions for patients in extremis. Noninvasive monitoring has generally been limited to transdermal or intravascular systems coupled to transducers including oxygen saturation or pressure....

Impact of anesthetics on oncogenic signaling network: a review on propofol and isoflurane.

Fundamental & clinical pharmacology

Saha P, Das A, Chatterjee N, Chakrabarti D, Sinha D.
PMID: 34655261
Fundam Clin Pharmacol. 2021 Oct 16; doi: 10.1111/fcp.12732. Epub 2021 Oct 16.

Propofol as an intravenous anesthetic and isoflurane as an inhalational/volatile anesthetic continue to be an important part of surgical anesthetic interventions worldwide. The impact of these anesthetics on tumor progression, immune modulation, and survival rates of cancer patients has...

Prolonged Volatile Anesthetic Exposure Exacerbates Cognitive Impairment and Neuropathology in the 5xFAD Mouse Model of Alzheimer's Disease.

Journal of Alzheimer's disease : JAD

Han F, Zhao J, Zhao G.
PMID: 34690137
J Alzheimers Dis. 2021 Oct 19; doi: 10.3233/JAD-210374. Epub 2021 Oct 19.

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disease which shows a set of symptoms involving cognitive changes and psychological changes. Given that AD is the most common form of dementia in aging population and the increasing demand for...

General Anaesthesia Shifts the Murine Circadian Clock in a Time-Dependant Fashion.

Clocks & sleep

Ludin NM, Orts-Sebastian A, Cheeseman JF, Chong J, Merry AF, Cumin D, Yamazaki S, Pawley MDM, Warman GR.
PMID: 33530488
Clocks Sleep. 2021 Jan 26;3(1):87-97. doi: 10.3390/clockssleep3010006.

Following general anaesthesia (GA), patients frequently experience sleep disruption and fatigue, which has been hypothesized to result at least in part by GA affecting the circadian clock. Here, we provide the first comprehensive time-dependent analysis of the effects of...

miR-124-3p Ameliorates Isoflurane-Induced Learning and Memory Impairment via Targeting STAT3 and Inhibiting Neuroinflammation.

Neuroimmunomodulation

Liu F, Qiu F, Chen H.
PMID: 34392240
Neuroimmunomodulation. 2021;28(4):248-254. doi: 10.1159/000515661. Epub 2021 Aug 13.

INTRODUCTION: Substantial evidence has indicated that isoflurane leads to learning and memory impairment. This study was designed to investigate the potential role of microRNA-124-3p (miR-124-3p) in isoflurane-induced learning and memory impairment in rats.METHODS: Spatial learning and memory of rats...

Impact of anesthesia on pathophysiology and mortality following subarachnoid hemorrhage in rats.

Experimental & translational stroke medicine

Hockel K, Trabold R, Schöller K, Török E, Plesnila N.
PMID: 22414527
Exp Transl Stroke Med. 2012 Mar 13;4(1):5. doi: 10.1186/2040-7378-4-5.

BACKGROUND: Anesthesia is indispensable for in vivo research but has the intrinsic potential to alter study results. The aim of the current study was to investigate the impact of three common anesthesia protocols on physiological parameters and outcome following...

Lateral Habenula Glutamatergic Neurons Modulate Isoflurane Anesthesia in Mice.

Frontiers in molecular neuroscience

Liu C, Liu J, Zhou L, He H, Zhang Y, Cai S, Yuan C, Luo T, Zheng J, Yu T, Zhang M.
PMID: 33746711
Front Mol Neurosci. 2021 Mar 04;14:628996. doi: 10.3389/fnmol.2021.628996. eCollection 2021.

Since their introduction in the 1840s, one of the largest mysteries of modern anesthesia are how general anesthetics create the state of reversible loss of consciousness. Increasing researchers have shown that neural pathways that regulate endogenous sleep-wake systems are...

A review of literature on substance abuse among anaesthesia providers.

Journal of research in nursing : JRN

DeFord S, Bonom J, Durbin T.
PMID: 34394581
J Res Nurs. 2019 Dec;24(8):587-600. doi: 10.1177/1744987119827353. Epub 2019 Mar 22.

BACKGROUND: Research has demonstrated that anaesthesia providers are susceptible to substance abuse. Several preventive measures are being implemented in certified registered nurse anaesthetist programmes to educate future providers about substance abuse. Given the continued prevalence and impact of the...

Quantitative MRI of cerebral arterial blood volume.

The open neuroimaging journal

Kim T, Kim SG.
PMID: 22253654
Open Neuroimag J. 2011;5:136-45. doi: 10.2174/1874440001105010136. Epub 2011 Nov 04.

Baseline cerebral arterial blood volume (CBV(a)) and its change are important for potential diagnosis of vascular dysfunctions, the determination of functional reactivity, and the interpretation of BOLD fMRI. To quantitative measure baseline CBV(a) non-invasively, we developed arterial spin labeling...

Roflumilast Ameliorates Isoflurane-Induced Inflammation in Astrocytes .

ACS omega

Zhang C, Xing Z, Tan M, Wu Y, Zeng W.
PMID: 33644540
ACS Omega. 2021 Feb 02;6(6):4167-4174. doi: 10.1021/acsomega.0c04799. eCollection 2021 Feb 16.

No abstract available.

Dynamics of isoflurane-induced vasodilation and blood flow of cerebral vasculature revealed by multi-exposure speckle imaging.

Journal of neuroscience methods

Sullender CT, Richards LM, He F, Luan L, Dunn AK.
PMID: 34863840
J Neurosci Methods. 2022 Jan 15;366:109434. doi: 10.1016/j.jneumeth.2021.109434. Epub 2021 Dec 01.

BACKGROUND: Anesthetized animal models are used extensively during neurophysiological and behavioral studies despite systemic effects from anesthesia that undermine both accurate interpretation and translation to awake human physiology. The majority of work examining the impact of anesthesia on cerebral...

Showing 997 to 1007 of 1007 entries