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Ethical issues and obligations with undocumented immigrants relying on emergency departments for dialysis.

Journal of the American College of Emergency Physicians open

Kluesner NH, McGrath N, Allen NG, Dilip M, Brenner J.
PMID: 35005702
J Am Coll Emerg Physicians Open. 2021 Dec 29;2(6):e12590. doi: 10.1002/emp2.12590. eCollection 2021 Dec.

Undocumented immigrants with end-stage renal disease in the United States are uniquely disadvantaged in their ability to access dialysis. This article examines the unique circumstances of the medical condition and healthcare system, including the relevant legal and regulatory influences...

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Kluesner NH, McGrath N, Allen NG, et al. Ethical issues and obligations with undocumented immigrants relying on emergency departments for dialysis. J Am Coll Emerg Physicians Open. 2021;2(6):e12590doi: 10.1002/emp2.12590.
Kluesner, N. H., McGrath, N., Allen, N. G., Dilip, M., & Brenner, J. (2021). Ethical issues and obligations with undocumented immigrants relying on emergency departments for dialysis. Journal of the American College of Emergency Physicians open, 2(6), e12590. https://doi.org/10.1002/emp2.12590
Kluesner, Nicholas H, et al. "Ethical issues and obligations with undocumented immigrants relying on emergency departments for dialysis." Journal of the American College of Emergency Physicians open vol. 2,6 (2021): e12590. doi: https://doi.org/10.1002/emp2.12590
Kluesner NH, McGrath N, Allen NG, Dilip M, Brenner J. Ethical issues and obligations with undocumented immigrants relying on emergency departments for dialysis. J Am Coll Emerg Physicians Open. 2021 Dec 29;2(6):e12590. doi: 10.1002/emp2.12590. eCollection 2021 Dec. PMID: 35005702; PMCID: PMC8716567.
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Therapeutic advances in medical oncology

Ros J, Baraibar I, Sardo E, Mulet N, Salvà F, Argilés G, Martini G, Ciardiello D, Cuadra JL, Tabernero J, Élez E.
PMID: 33747149
Ther Adv Med Oncol. 2021 Feb 22;13:1758835921992974. doi: 10.1177/1758835921992974. eCollection 2021.

AREAS COVERED: This review addresses the development of therapeutic strategies with inhibitors targeting MAPK/ERK and EXPERT OPINION: Exploiting knowledge of the mechanisms of resistance to

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Ros J, Baraibar I, Sardo E, et al. . Ther Adv Med Oncol. 2021;13:1758835921992974doi: 10.1177/1758835921992974.
Ros, J., Baraibar, I., Sardo, E., Mulet, N., Salvà, F., Argilés, G., Martini, G., Ciardiello, D., Cuadra, J. L., Tabernero, J., & Élez, E. (2021). . Therapeutic advances in medical oncology, 131758835921992974. https://doi.org/10.1177/1758835921992974
Ros, Javier, et al. "." Therapeutic advances in medical oncology vol. 13 (2021): 1758835921992974. doi: https://doi.org/10.1177/1758835921992974
Ros J, Baraibar I, Sardo E, Mulet N, Salvà F, Argilés G, Martini G, Ciardiello D, Cuadra JL, Tabernero J, Élez E. . Ther Adv Med Oncol. 2021 Feb 22;13:1758835921992974. doi: 10.1177/1758835921992974. eCollection 2021. PMID: 33747149; PMCID: PMC7903827.
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Impaired Cx43 gap junction endocytosis causes morphological and functional defects in zebrafish.

Molecular biology of the cell

Hyland C, Mfarej M, Hiotis G, Lancaster S, Novak N, Iovine MK, Falk MM.
PMID: 34379446
Mol Biol Cell. 2021 Oct 01;32(20):ar13. doi: 10.1091/mbc.E20-12-0797. Epub 2021 Aug 11.

Gap junctions mediate direct cell-to-cell communication by forming channels that physically couple cells, thereby linking their cytoplasm, permitting the exchange of molecules, ions, and electrical impulses. Gap junctions are assembled from connexin (Cx) proteins, with connexin 43 (Cx43) being...

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Hyland C, Mfarej M, Hiotis G, et al. Impaired Cx43 gap junction endocytosis causes morphological and functional defects in zebrafish. Mol Biol Cell. 2021;32(20):ar13doi: 10.1091/mbc.E20-12-0797.
Hyland, C., Mfarej, M., Hiotis, G., Lancaster, S., Novak, N., Iovine, M. K., & Falk, M. M. (2021). Impaired Cx43 gap junction endocytosis causes morphological and functional defects in zebrafish. Molecular biology of the cell, 32(20), ar13. https://doi.org/10.1091/mbc.E20-12-0797
Hyland, Caitlin, et al. "Impaired Cx43 gap junction endocytosis causes morphological and functional defects in zebrafish." Molecular biology of the cell vol. 32,20 (2021): ar13. doi: https://doi.org/10.1091/mbc.E20-12-0797
Hyland C, Mfarej M, Hiotis G, Lancaster S, Novak N, Iovine MK, Falk MM. Impaired Cx43 gap junction endocytosis causes morphological and functional defects in zebrafish. Mol Biol Cell. 2021 Oct 01;32(20):ar13. doi: 10.1091/mbc.E20-12-0797. Epub 2021 Aug 11. PMID: 34379446; PMCID: PMC8684743.
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Ribavirin Aerosol in the Treatment of SARS-CoV-2: A Case Series.

Infectious diseases and therapy

Messina E, Danise A, Ferrari G, Andolina A, Chiurlo M, Razanakolona M, Barakat M, Israel RJ, Castagna A.
PMID: 34302258
Infect Dis Ther. 2021 Dec;10(4):2791-2804. doi: 10.1007/s40121-021-00493-9. Epub 2021 Jul 23.

Ribavirin is an inosine monophosphate dehydrogenase inhibitor with demonstrated activity against coronaviruses, including SARS-CoV-2. Five hospitalized patients with COVID-19 (confirmed by positive tests for SARS-CoV-2) received treatment with ribavirin for inhalation solution (ribavirin aerosol) as part of a compassionate...

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Messina E, Danise A, Ferrari G, et al. Ribavirin Aerosol in the Treatment of SARS-CoV-2: A Case Series. Infect Dis Ther. 2021;10(4):2791-2804doi: 10.1007/s40121-021-00493-9.
Messina, E., Danise, A., Ferrari, G., Andolina, A., Chiurlo, M., Razanakolona, M., Barakat, M., Israel, R. J., & Castagna, A. (2021). Ribavirin Aerosol in the Treatment of SARS-CoV-2: A Case Series. Infectious diseases and therapy, 10(4), 2791-2804. https://doi.org/10.1007/s40121-021-00493-9
Messina, Emanuela, et al. "Ribavirin Aerosol in the Treatment of SARS-CoV-2: A Case Series." Infectious diseases and therapy vol. 10,4 (2021): 2791-2804. doi: https://doi.org/10.1007/s40121-021-00493-9
Messina E, Danise A, Ferrari G, Andolina A, Chiurlo M, Razanakolona M, Barakat M, Israel RJ, Castagna A. Ribavirin Aerosol in the Treatment of SARS-CoV-2: A Case Series. Infect Dis Ther. 2021 Dec;10(4):2791-2804. doi: 10.1007/s40121-021-00493-9. Epub 2021 Jul 23. PMID: 34302258; PMCID: PMC8302211.
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Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†.

Biology of reproduction

Torres MA, Pedrosa AC, Novais FJ, Alkmin DV, Cooper BR, Yasui GS, Fukumasu H, Machaty Z, de Andrade AFC.
PMID: 34725678
Biol Reprod. 2022 Jan 13;106(1):213-226. doi: 10.1093/biolre/ioab200.

Holding at room temperature is the first step in most boar semen cryopreservation protocols. It is well accepted that a holding time (HT) of 24 h increases sperm cryotolerance. However, the effect of HT on ejaculates with different freezability...

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Torres MA, Pedrosa AC, Novais FJ, et al. Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†. Biol Reprod. 2022;106(1):213-226doi: 10.1093/biolre/ioab200.
Torres, M. A., Pedrosa, A. C., Novais, F. J., Alkmin, D. V., Cooper, B. R., Yasui, G. S., Fukumasu, H., Machaty, Z., & de Andrade, A. F. C. (2022). Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†. Biology of reproduction, 106(1), 213-226. https://doi.org/10.1093/biolre/ioab200
Torres, Mariana A, et al. "Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†." Biology of reproduction vol. 106,1 (2022): 213-226. doi: https://doi.org/10.1093/biolre/ioab200
Torres MA, Pedrosa AC, Novais FJ, Alkmin DV, Cooper BR, Yasui GS, Fukumasu H, Machaty Z, de Andrade AFC. Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†. Biol Reprod. 2022 Jan 13;106(1):213-226. doi: 10.1093/biolre/ioab200. PMID: 34725678.
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Acute severe autoimmune hepatitis with anti-rods and rings autoantibodies; literature first evidence.

Gastroenterology and hepatology from bed to bench

Assandri R, Montanelli A.
PMID: 33868616
Gastroenterol Hepatol Bed Bench. 2021;14(1):89-94.

Autoimmune hepatitis (AIH) was defined as a progressive, chronic inflammatory autoimmune liver disease (ALD). The diagnosis of AIH requires the presence of characteristic clinical and laboratory features, and the exclusion of other clinical conditions that cause chronic hepatitis and...

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Assandri R, Montanelli A. Acute severe autoimmune hepatitis with anti-rods and rings autoantibodies; literature first evidence. Gastroenterol Hepatol Bed Bench. 2021;14(1):89-94
Assandri, R., & Montanelli, A. (2021). Acute severe autoimmune hepatitis with anti-rods and rings autoantibodies; literature first evidence. Gastroenterology and hepatology from bed to bench, 14(1), 89-94.
Assandri, Roberto, and Montanelli, Alessandro. "Acute severe autoimmune hepatitis with anti-rods and rings autoantibodies; literature first evidence." Gastroenterology and hepatology from bed to bench vol. 14,1 (2021): 89-94.
Assandri R, Montanelli A. Acute severe autoimmune hepatitis with anti-rods and rings autoantibodies; literature first evidence. Gastroenterol Hepatol Bed Bench. 2021;14(1):89-94. PMID: 33868616; PMCID: PMC8035537.
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Increased Height of Fused Segments Contributes to Early-Phase Strut Subsidence after Anterior Cervical Corpectomy with Fusion for Multilevel Ossification of the Posterior Longitudinal Ligament.

Spine surgery and related research

Hirai T, Yoshii T, Egawa S, Sakai K, Inose H, Yuasa M, Yamada T, Ushio S, Kato T, Arai Y, Kawabata S, Shindo S, Nakai O, Okawa A.
PMID: 33195852
Spine Surg Relat Res. 2020 Mar 19;4(4):294-299. doi: 10.22603/ssrr.2019-0102. eCollection 2020.

INTRODUCTION: Anterior decompression and fusion have shown favorable neurologic outcomes in patients with cervical myelopathy. However, implant migration sometimes occurs immediately after multilevel anterior cervical corpectomy with fusion (ACCF). Risk factors associated with early bone graft migration have not...

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Hirai T, Yoshii T, Egawa S, et al. Increased Height of Fused Segments Contributes to Early-Phase Strut Subsidence after Anterior Cervical Corpectomy with Fusion for Multilevel Ossification of the Posterior Longitudinal Ligament. Spine Surg Relat Res. 2020;4(4):294-299doi: 10.22603/ssrr.2019-0102.
Hirai, T., Yoshii, T., Egawa, S., Sakai, K., Inose, H., Yuasa, M., Yamada, T., Ushio, S., Kato, T., Arai, Y., Kawabata, S., Shindo, S., Nakai, O., & Okawa, A. (2020). Increased Height of Fused Segments Contributes to Early-Phase Strut Subsidence after Anterior Cervical Corpectomy with Fusion for Multilevel Ossification of the Posterior Longitudinal Ligament. Spine surgery and related research, 4(4), 294-299. https://doi.org/10.22603/ssrr.2019-0102
Hirai, Takashi, et al. "Increased Height of Fused Segments Contributes to Early-Phase Strut Subsidence after Anterior Cervical Corpectomy with Fusion for Multilevel Ossification of the Posterior Longitudinal Ligament." Spine surgery and related research vol. 4,4 (2020): 294-299. doi: https://doi.org/10.22603/ssrr.2019-0102
Hirai T, Yoshii T, Egawa S, Sakai K, Inose H, Yuasa M, Yamada T, Ushio S, Kato T, Arai Y, Kawabata S, Shindo S, Nakai O, Okawa A. Increased Height of Fused Segments Contributes to Early-Phase Strut Subsidence after Anterior Cervical Corpectomy with Fusion for Multilevel Ossification of the Posterior Longitudinal Ligament. Spine Surg Relat Res. 2020 Mar 19;4(4):294-299. doi: 10.22603/ssrr.2019-0102. eCollection 2020. PMID: 33195852; PMCID: PMC7661025.
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Metabolomic profiles in relation to benchmark polycyclic aromatic compounds (PACs) and trace elements in two seabird species from Arctic Canada.

Environmental research

Sarma SN, Thomas PJ, Naz S, Pauli B, Crump D, Zahaby Y, O'Brien JM, Mallory ML, Franckowiak RP, Gendron M, Provencher JF.
PMID: 34506783
Environ Res. 2021 Sep 08;204:112022. doi: 10.1016/j.envres.2021.112022. Epub 2021 Sep 08.

While exposure of birds to oil-related contaminants has been documented, the related adverse effects this exposure has on Arctic marine birds remain unexplored. Metabolomics can play an important role to explore biologically relevant metabolite biomarkers in relation to different...

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Sarma SN, Thomas PJ, Naz S, et al. Metabolomic profiles in relation to benchmark polycyclic aromatic compounds (PACs) and trace elements in two seabird species from Arctic Canada. Environ Res. 2021;204:112022doi: 10.1016/j.envres.2021.112022.
Sarma, S. N., Thomas, P. J., Naz, S., Pauli, B., Crump, D., Zahaby, Y., O'Brien, J. M., Mallory, M. L., Franckowiak, R. P., Gendron, M., & Provencher, J. F. (2021). Metabolomic profiles in relation to benchmark polycyclic aromatic compounds (PACs) and trace elements in two seabird species from Arctic Canada. Environmental research, 204112022. https://doi.org/10.1016/j.envres.2021.112022
Sarma, Sailendra Nath, et al. "Metabolomic profiles in relation to benchmark polycyclic aromatic compounds (PACs) and trace elements in two seabird species from Arctic Canada." Environmental research vol. 204 (2021): 112022. doi: https://doi.org/10.1016/j.envres.2021.112022
Sarma SN, Thomas PJ, Naz S, Pauli B, Crump D, Zahaby Y, O'Brien JM, Mallory ML, Franckowiak RP, Gendron M, Provencher JF. Metabolomic profiles in relation to benchmark polycyclic aromatic compounds (PACs) and trace elements in two seabird species from Arctic Canada. Environ Res. 2021 Sep 08;204:112022. doi: 10.1016/j.envres.2021.112022. Epub 2021 Sep 08. PMID: 34506783.
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PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastric cancer.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Evrard C, Louvet C, Hajbi FE, Fiore FD, Malicot KL, Aparicio T, Bouché O, Laurent-Puig P, Bibeau F, Lecomte T, Lièvre A, Guimbaud R, Kim S, Zaanan A, Sokol H, Chibaudel B, Desrame J, Pierre S, Gonzalez D, Lepage C, Tougeron D.
PMID: 33358124
Dig Liver Dis. 2021 Apr;53(4):420-426. doi: 10.1016/j.dld.2020.11.036. Epub 2021 Jan 06.

Gastric or gastro-oesophageal junction (GEJ) adenocarcinomas present poor overall survival (OS). First-line chemotherapy regimen for patients with HER2-negative tumours is based on a doublet or triplet of fluoropyrimidine plus platinum salt ± taxane. Second-line chemotherapy (Docetaxel or Irinotecan) improves...

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Evrard C, Louvet C, Hajbi FE, et al. PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastric cancer. Dig Liver Dis. 2021;53(4):420-426doi: 10.1016/j.dld.2020.11.036.
Evrard, C., Louvet, C., Hajbi, F. E., Fiore, F. D., Malicot, K. L., Aparicio, T., Bouché, O., Laurent-Puig, P., Bibeau, F., Lecomte, T., Lièvre, A., Guimbaud, R., Kim, S., Zaanan, A., Sokol, H., Chibaudel, B., Desrame, J., Pierre, S., Gonzalez, D., Lepage, C., & Tougeron, D. (2021). PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastric cancer. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 53(4), 420-426. https://doi.org/10.1016/j.dld.2020.11.036
Evrard, Camille, et al. "PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastric cancer." Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver vol. 53,4 (2021): 420-426. doi: https://doi.org/10.1016/j.dld.2020.11.036
Evrard C, Louvet C, Hajbi FE, Fiore FD, Malicot KL, Aparicio T, Bouché O, Laurent-Puig P, Bibeau F, Lecomte T, Lièvre A, Guimbaud R, Kim S, Zaanan A, Sokol H, Chibaudel B, Desrame J, Pierre S, Gonzalez D, Lepage C, Tougeron D. PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastric cancer. Dig Liver Dis. 2021 Apr;53(4):420-426. doi: 10.1016/j.dld.2020.11.036. Epub 2021 Jan 06. PMID: 33358124.
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Metabolite profiling of the post-ovulatory oocytes of the common carp, Cyprinus carpio: A .

Comparative biochemistry and physiology. Part D, Genomics & proteomics

Hajirezaee S, Abed-Elmdoust A, Alekhina N, Chupradit S, Mustafa YF.
PMID: 34607241
Comp Biochem Physiol Part D Genomics Proteomics. 2021 Dec;40:100917. doi: 10.1016/j.cbd.2021.100917. Epub 2021 Sep 28.

A metabolomics study was conducted to investigate the molecular bases of oocyte over-ripening in common carp, Cyprinus carpio from a metabolic point of view. The ovulation was induced in fish brooders by intramuscular injection of pituitary extract and oocytes...

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Hajirezaee S, Abed-Elmdoust A, Alekhina N, et al. Metabolite profiling of the post-ovulatory oocytes of the common carp, Cyprinus carpio: A . Comp Biochem Physiol Part D Genomics Proteomics. 2021;40:100917doi: 10.1016/j.cbd.2021.100917.
Hajirezaee, S., Abed-Elmdoust, A., Alekhina, N., Chupradit, S., & Mustafa, Y. F. (2021). Metabolite profiling of the post-ovulatory oocytes of the common carp, Cyprinus carpio: A . Comparative biochemistry and physiology. Part D, Genomics & proteomics, 40100917. https://doi.org/10.1016/j.cbd.2021.100917
Hajirezaee, Saeed, et al. "Metabolite profiling of the post-ovulatory oocytes of the common carp, Cyprinus carpio: A ." Comparative biochemistry and physiology. Part D, Genomics & proteomics vol. 40 (2021): 100917. doi: https://doi.org/10.1016/j.cbd.2021.100917
Hajirezaee S, Abed-Elmdoust A, Alekhina N, Chupradit S, Mustafa YF. Metabolite profiling of the post-ovulatory oocytes of the common carp, Cyprinus carpio: A . Comp Biochem Physiol Part D Genomics Proteomics. 2021 Dec;40:100917. doi: 10.1016/j.cbd.2021.100917. Epub 2021 Sep 28. PMID: 34607241.
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Mapping of integrated PIN diodes with a 3D architecture by scanning microwave impedance microscopy and dynamic spectroscopy.

Beilstein journal of nanotechnology

Coq Germanicus R, De Wolf P, Lallemand F, Bunel C, Bardy S, Murray H, Lüders U.
PMID: 33299736
Beilstein J Nanotechnol. 2020 Nov 23;11:1764-1775. doi: 10.3762/bjnano.11.159. eCollection 2020.

This work addresses the need for a comprehensive methodology for nanoscale electrical testing dedicated to the analysis of both "front end of line" (FEOL) (doped semiconducting layers) and "back end of line" (BEOL) layers (metallization, trench dielectric, and isolation)...

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Coq Germanicus R, De Wolf P, Lallemand F, et al. Mapping of integrated PIN diodes with a 3D architecture by scanning microwave impedance microscopy and dynamic spectroscopy. Beilstein J Nanotechnol. 2020;11:1764-1775doi: 10.3762/bjnano.11.159.
Coq Germanicus, R., De Wolf, P., Lallemand, F., Bunel, C., Bardy, S., Murray, H., & Lüders, U. (2020). Mapping of integrated PIN diodes with a 3D architecture by scanning microwave impedance microscopy and dynamic spectroscopy. Beilstein journal of nanotechnology, 111764-1775. https://doi.org/10.3762/bjnano.11.159
Coq Germanicus, Rosine, et al. "Mapping of integrated PIN diodes with a 3D architecture by scanning microwave impedance microscopy and dynamic spectroscopy." Beilstein journal of nanotechnology vol. 11 (2020): 1764-1775. doi: https://doi.org/10.3762/bjnano.11.159
Coq Germanicus R, De Wolf P, Lallemand F, Bunel C, Bardy S, Murray H, Lüders U. Mapping of integrated PIN diodes with a 3D architecture by scanning microwave impedance microscopy and dynamic spectroscopy. Beilstein J Nanotechnol. 2020 Nov 23;11:1764-1775. doi: 10.3762/bjnano.11.159. eCollection 2020. PMID: 33299736; PMCID: PMC7705862.
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Thermal Processing of a Degradable Carboxylic Acid-Functionalized Polycarbonate into Scaffolds for Tissue Engineering.

Polymer engineering and science

Murthy NS, Shultz RB, Iovine CP, Kohn J.
PMID: 34421132
Polym Eng Sci. 2021 Jul;61(7):2012-2022. doi: 10.1002/pen.25716. Epub 2021 May 22.

Degradable polymers are often desirable for the fabrication of medical implants, but thermal processing of these polymers is a challenge. We describe here how these problems can be addressed by discussing the extrusion of fibers and injection molding of...

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Murthy NS, Shultz RB, Iovine CP, et al. Thermal Processing of a Degradable Carboxylic Acid-Functionalized Polycarbonate into Scaffolds for Tissue Engineering. Polym Eng Sci. 2021;61(7):2012-2022doi: 10.1002/pen.25716.
Murthy, N. S., Shultz, R. B., Iovine, C. P., & Kohn, J. (2021). Thermal Processing of a Degradable Carboxylic Acid-Functionalized Polycarbonate into Scaffolds for Tissue Engineering. Polymer engineering and science, 61(7), 2012-2022. https://doi.org/10.1002/pen.25716
Murthy, N Sanjeeva, et al. "Thermal Processing of a Degradable Carboxylic Acid-Functionalized Polycarbonate into Scaffolds for Tissue Engineering." Polymer engineering and science vol. 61,7 (2021): 2012-2022. doi: https://doi.org/10.1002/pen.25716
Murthy NS, Shultz RB, Iovine CP, Kohn J. Thermal Processing of a Degradable Carboxylic Acid-Functionalized Polycarbonate into Scaffolds for Tissue Engineering. Polym Eng Sci. 2021 Jul;61(7):2012-2022. doi: 10.1002/pen.25716. Epub 2021 May 22. PMID: 34421132; PMCID: PMC8378799.
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