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Showing 2197 to 2208 of 2217 entries
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Anti-inflammatory Treatment of Kawasaki Disease: Comparison of Current Guidelines and Perspectives.

Frontiers in medicine

Buda P, Friedman-Gruszczyńska J, Książyk J.
PMID: 34917629
Front Med (Lausanne). 2021 Nov 30;8:738850. doi: 10.3389/fmed.2021.738850. eCollection 2021.

Kawasaki disease (KD), an acute, generalized vasculitis, is associated with an increased risk of coronary heart disease and is the most common cause of acquired heart disease in childhood. The incidence of KD is increasing worldwide. There are numerous...

A case of multisystem inflammatory syndrome (MIS-A) in an adult woman 18 days after COVID-19 vaccination.

Acta clinica Belgica

Stappers S, Ceuleers B, Van Brusselen D, Willems P, de Tavernier B, Verlinden A.
PMID: 34511054
Acta Clin Belg. 2021 Sep 12;1-6. doi: 10.1080/17843286.2021.1977899. Epub 2021 Sep 12.

We discuss a case of a young woman, presenting a constellation of clinical and biochemical features meeting the current case definition of multisystem inflammatory syndrome in adults (MIS-A), 18 days after receiving her first dose of the Oxford/AstraZeneca vaccine....

Development of Anti-.

ImmunoTargets and therapy

Lillo AM, Velappan N, Kelliher JM, Watts AJ, Merriman SP, Vuyisich G, Lilley LM, Coombs KE, Mastren T, Teshima M, Stein BW, Wagner GL, Iyer S, Bradbury ARM, Harris JF, Dichosa AE, Kozimor SA.
PMID: 33294421
Immunotargets Ther. 2020 Nov 27;9:299-316. doi: 10.2147/ITT.S267077. eCollection 2020.

METHODS: Here, we describe a set of human monoclonal immunoglobulins (IgG1s) targeting RESULTS: Two of our anti-F1 IgG (αF1Ig 2 and αF1Ig 8) stood out for high production yield, specificity, and stability. These two antibodies were additionally attractive in...

Variability of Murine Pregnancy Outcome Resulting from Passive Immunization with Anticardiolipin Antibody-Positive Immunoglobulin G.

Journal of maternal-fetal investigation : the official journal of French Society of Ultrasound in Medicine and Biology ... [et al.]

Silver RK, Russell TL, Brodin AG, Check IJ, Helfand BT, Caplan MS.
PMID: 9524158
J Matern Fetal Investig. 1998 Mar;8(1):35-8.

>Objective: Administration of purified human IgG from antiphospholipid syndrome patients has not consistently caused murine pregnancy loss despite the presence of significant anticardiolipin antibody (ACA) activity. We evaluated whether a correlation exists between ACA activity and the degree of...

Changes in lymphocytes, neutrophils and immunoglobulins in year-1 cladribine treatment in multiple sclerosis.

Multiple sclerosis and related disorders

Spiezia AL, Cerbone V, Molinari EA, Capasso N, Lanzillo R, Carotenuto A, Petracca M, Novarella F, Covelli B, Scalia G, Brescia Morra V, Moccia M.
PMID: 34871857
Mult Scler Relat Disord. 2021 Nov 29;57:103431. doi: 10.1016/j.msard.2021.103431. Epub 2021 Nov 29.

No abstract available.

Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein.

Vaccine: X

DiMuzio JM, Heimbach BC, Howanski RJ, Dowling JP, Patel NB, Henriquez N, Nicolescu C, Nath M, Polley A, Bingaman JL, Smith T, Harman BC, Robinson MK, Morin MJ, Nikitin PA.
PMID: 33937741
Vaccine X. 2021 Aug;8:100098. doi: 10.1016/j.jvacx.2021.100098. Epub 2021 Apr 24.

Patients who recover from SARS-CoV-2 infections produce antibodies and antigen-specific T cells against multiple viral proteins. Here, an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent patients has been performed by generating large, stable hybridoma libraries...

Successful Treatment of Vaccine-Induced Immune Thrombotic Thrombocytopenia in a 26-Year-Old Female Patient.

Acta haematologica

Kemper M, Lenz G, Mesters RM.
PMID: 34614491
Acta Haematol. 2021 Oct 06;1-4. doi: 10.1159/000519451. Epub 2021 Oct 06.

Vaccine-induced immune thrombotic thrombocytopenia (VITT) has already been described after vaccination with ChAdOx2 nCov-19 (AstraZeneca) and Ad26.COV2.S (Johnson & Johnson/Janssen). However, less knowledge so far has been gained about optimal therapeutic regimens in VITT-suspected patients. Here, we report the...

COVID-19-associated immune-mediated encephalitis mimicking acute-onset Creutzfeldt-Jakob disease.

Annals of clinical and translational neurology

Beretta S, Stabile A, Balducci C, DiFrancesco JC, Patruno A, Rona R, Bombino M, Capraro C, Andreetta F, Cavalcante P, Moda F, Citerio G, Foti G, Bogliun G, Ferrarese C.
PMID: 34825771
Ann Clin Transl Neurol. 2021 Dec;8(12):2314-2318. doi: 10.1002/acn3.51479. Epub 2021 Nov 26.

We report a subtype of immune-mediated encephalitis associated with COVID-19, which closely mimics acute-onset sporadic Creutzfeldt-Jakob disease. A 64-year-old man presented with confusion, aphasia, myoclonus, and a silent interstitial pneumonia. He tested positive for SARS-CoV-2. Cognition and myoclonus rapidly...

A review of severe thrombocytopenia in Zika patients - Pathophysiology, treatment and outcome.

Travel medicine and infectious disease

De Pijper CA, Schnyder JL, Stijnis C, Goorhuis A, Grobusch MP.
PMID: 34896327
Travel Med Infect Dis. 2021 Dec 08;45:102231. doi: 10.1016/j.tmaid.2021.102231. Epub 2021 Dec 08.

BACKGROUND: During the 2015 Zika virus infection (ZVI) epidemic swiping through the Americas, few cases of ZVI with severe, potentially life-threatening thrombocytopenia were reported. Platelet transfusion, corticosteroids and intravenous immunoglobulins (IVIG) were in most cases applied as therapeutic options,...

Fc Engineering Strategies to Advance IgA Antibodies as Therapeutic Agents.

Antibodies (Basel, Switzerland)

van Tetering G, Evers M, Chan C, Stip M, Leusen J.
PMID: 33333967
Antibodies (Basel). 2020 Dec 15;9(4). doi: 10.3390/antib9040070.

In the past three decades, a great interest has arisen in the use of immunoglobulins as therapeutic agents. In particular, since the approval of the first monoclonal antibody Rituximab for B cell malignancies, the progress in the antibody-related therapeutic...

Systemic burden and cardiovascular risk to Porphyromonas species in apical periodontitis.

Clinical oral investigations

Jiménez C, Garrido M, Pussinen P, Bordagaray MJ, Fernández A, Vega C, Chaparro A, Hoare A, Hernández M.
PMID: 34313848
Clin Oral Investig. 2021 Jul 27; doi: 10.1007/s00784-021-04083-4. Epub 2021 Jul 27.

OBJECTIVE: Porphyromonas (P.) species (spp.) are a major etiological agent of apical periodontitis (AP), which in turn represents a risk factor for cardiovascular diseases. This study explored the associations between endodontic infection with Porphyromonas species, the systemic bacterial burden,...

Effective presence of antibodies against common human coronavirus in IgG immunoglobulin medicinal products.: Antibodies to common coronaviruses in IgG medicinal products.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Díez JM, Romero C, Gajardo R.
PMID: 34929360
Int J Infect Dis. 2021 Dec 17; doi: 10.1016/j.ijid.2021.12.329. Epub 2021 Dec 17.

BACKGROUND: In these studies, immunoglobulin (IgG) products (IV, IM, SC) prepared from geographically diverse plasma pools were tested for activity against common human coronaviruses (HCoV). Products from plasma obtained from Germany, Czech Republic, Slovak Republic, USA, and Spain were...

Showing 2197 to 2208 of 2217 entries