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Suppression of IgM Proteolysis by Conformational Stabilization Through Excipients.

Scientia pharmaceutica

Mueller M, Loh MQ, Gagnon P.
PMID: 26839826
Sci Pharm. 2015 Mar 04;83(2):401-10. doi: 10.3797/scipharm.1501-12. Print 2015.

Protease activity from host cell lines may cause product loss or affect the quality of recombinant proteins. In this study, we showed that excipients like glycine and sorbitol reduce the proteolysis of an immunoglobulin M (IgM) in the presence...

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Mueller M, Loh MQ, Gagnon P. Suppression of IgM Proteolysis by Conformational Stabilization Through Excipients. Sci Pharm. 2015;83(2):401-10doi: 10.3797/scipharm.1501-12.
Mueller, M., Loh, M. Q., & Gagnon, P. (2015). Suppression of IgM Proteolysis by Conformational Stabilization Through Excipients. Scientia pharmaceutica, 83(2), 401-10. https://doi.org/10.3797/scipharm.1501-12
Mueller, Monika, et al. "Suppression of IgM Proteolysis by Conformational Stabilization Through Excipients." Scientia pharmaceutica vol. 83,2 (2015): 401-10. doi: https://doi.org/10.3797/scipharm.1501-12
Mueller M, Loh MQ, Gagnon P. Suppression of IgM Proteolysis by Conformational Stabilization Through Excipients. Sci Pharm. 2015 Mar 04;83(2):401-10. doi: 10.3797/scipharm.1501-12. Print 2015. PMID: 26839826; PMCID: PMC4727821.
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Salvage therapy with high dose Intravenous Immunoglobulins in acquired Von Willebrand Syndrome and unresponsive severe intestinal bleeding.

Experimental hematology & oncology

Cugno M, Tedeschi A, Siboni SM, Stufano F, Depetri F, Franchi F, Griffini S, Peyvandi F.
PMID: 24926417
Exp Hematol Oncol. 2014 Jun 04;3:15. doi: 10.1186/2162-3619-3-15. eCollection 2014.

A 91-year-old woman affected with acquired Von Willebrand (VW) syndrome and intestinal angiodysplasias presented with severe gastrointestinal bleeding (hemoglobin 5 g/dl). Despite replacement therapy with VW factor/factor VIII concentrate qid, bleeding did not stop (eleven packed red blood cell...

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Cugno M, Tedeschi A, Siboni SM, et al. Salvage therapy with high dose Intravenous Immunoglobulins in acquired Von Willebrand Syndrome and unresponsive severe intestinal bleeding. Exp Hematol Oncol. 2014;3:15doi: 10.1186/2162-3619-3-15.
Cugno, M., Tedeschi, A., Siboni, S. M., Stufano, F., Depetri, F., Franchi, F., Griffini, S., & Peyvandi, F. (2014). Salvage therapy with high dose Intravenous Immunoglobulins in acquired Von Willebrand Syndrome and unresponsive severe intestinal bleeding. Experimental hematology & oncology, 315. https://doi.org/10.1186/2162-3619-3-15
Cugno, Massimo, et al. "Salvage therapy with high dose Intravenous Immunoglobulins in acquired Von Willebrand Syndrome and unresponsive severe intestinal bleeding." Experimental hematology & oncology vol. 3 (2014): 15. doi: https://doi.org/10.1186/2162-3619-3-15
Cugno M, Tedeschi A, Siboni SM, Stufano F, Depetri F, Franchi F, Griffini S, Peyvandi F. Salvage therapy with high dose Intravenous Immunoglobulins in acquired Von Willebrand Syndrome and unresponsive severe intestinal bleeding. Exp Hematol Oncol. 2014 Jun 04;3:15. doi: 10.1186/2162-3619-3-15. eCollection 2014. PMID: 24926417; PMCID: PMC4055248.
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Immunological Evidence for the Existence of a Carrier Protein for Sucrose Transport in Tonoplast Vesicles from Red Beet (Beta vulgaris L.) Root Storage Tissue.

Plant physiology

Getz HP, Grosclaude J, Kurkdjian A, Lelievre F, Maretzki A, Guern J.
PMID: 12231863
Plant Physiol. 1993 Jul;102(3):751-760. doi: 10.1104/pp.102.3.751.

Monoclonal antibodies were raised in mice against a highly purified tonoplast fraction from isolated red beet (Beta vulgaris L. ssp. conditiva) root vacuoles. Positive hybridoma clones and sub-clones were identified by prescreening using an enzyme-linked immunosorbent assay (ELISA) and...

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Getz HP, Grosclaude J, Kurkdjian A, et al. Immunological Evidence for the Existence of a Carrier Protein for Sucrose Transport in Tonoplast Vesicles from Red Beet (Beta vulgaris L.) Root Storage Tissue. Plant Physiol. 1993;102(3):751-760doi: 10.1104/pp.102.3.751.
Getz, H. P., Grosclaude, J., Kurkdjian, A., Lelievre, F., Maretzki, A., & Guern, J. (1993). Immunological Evidence for the Existence of a Carrier Protein for Sucrose Transport in Tonoplast Vesicles from Red Beet (Beta vulgaris L.) Root Storage Tissue. Plant physiology, 102(3), 751-760. https://doi.org/10.1104/pp.102.3.751
Getz, H. P., et al. "Immunological Evidence for the Existence of a Carrier Protein for Sucrose Transport in Tonoplast Vesicles from Red Beet (Beta vulgaris L.) Root Storage Tissue." Plant physiology vol. 102,3 (1993): 751-760. doi: https://doi.org/10.1104/pp.102.3.751
Getz HP, Grosclaude J, Kurkdjian A, Lelievre F, Maretzki A, Guern J. Immunological Evidence for the Existence of a Carrier Protein for Sucrose Transport in Tonoplast Vesicles from Red Beet (Beta vulgaris L.) Root Storage Tissue. Plant Physiol. 1993 Jul;102(3):751-760. doi: 10.1104/pp.102.3.751. PMID: 12231863; PMCID: PMC158844.
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Subacute transverse myelitis with Lyme profile dissociation.

German medical science : GMS e-journal

Walid MS, Ajjan M, Ulm AJ.
PMID: 19675732
Ger Med Sci. 2008 Jun 10;6:Doc04.

INTRODUCTION: Transverse myelitis is a very rare neurologic syndrome with an incidence per year of 1-5 per million population. We are presenting an interesting case of subacute transverse myelitis with its MRI (magnetic resonance imaging) and CSF (cerebrospinal fluid)...

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Walid MS, Ajjan M, Ulm AJ. Subacute transverse myelitis with Lyme profile dissociation. Ger Med Sci. 2008;6:Doc04
Walid, M. S., Ajjan, M., & Ulm, A. J. (2008). Subacute transverse myelitis with Lyme profile dissociation. German medical science : GMS e-journal, 6Doc04.
Walid, M Sami, et al. "Subacute transverse myelitis with Lyme profile dissociation." German medical science : GMS e-journal vol. 6 (2008): Doc04.
Walid MS, Ajjan M, Ulm AJ. Subacute transverse myelitis with Lyme profile dissociation. Ger Med Sci. 2008 Jun 10;6:Doc04. PMID: 19675732; PMCID: PMC2703261.
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A middle-aged female with recurrent sinopulmonary infections: a case report.

Journal of medical case reports

Yalavarthy UC, Panda M.
PMID: 18426600
J Med Case Rep. 2008 Apr 21;2:117. doi: 10.1186/1752-1947-2-117.

INTRODUCTION: Common variable immunodeficiency (CVID) is a form of severe antibody deficiency with an estimated prevalence of 1 in 25,000 to 1 in 100,000. The disorder apparently results from currently undefined immune deregulations resulting in failed B-cell differentiation with...

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Yalavarthy UC, Panda M. A middle-aged female with recurrent sinopulmonary infections: a case report. J Med Case Rep. 2008;2:117doi: 10.1186/1752-1947-2-117.
Yalavarthy, U. C., & Panda, M. (2008). A middle-aged female with recurrent sinopulmonary infections: a case report. Journal of medical case reports, 2117. https://doi.org/10.1186/1752-1947-2-117
Yalavarthy, Umesh C, and Panda, Mukta. "A middle-aged female with recurrent sinopulmonary infections: a case report." Journal of medical case reports vol. 2 (2008): 117. doi: https://doi.org/10.1186/1752-1947-2-117
Yalavarthy UC, Panda M. A middle-aged female with recurrent sinopulmonary infections: a case report. J Med Case Rep. 2008 Apr 21;2:117. doi: 10.1186/1752-1947-2-117. PMID: 18426600; PMCID: PMC2365966.
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Bovine venereal vibriosis: variations in immunoglobulin class of antibodies in genital secretions and serum.

Infection and immunity

Corbeil LB, Duncan JR, Schurig GG, Hall CE, Winter AJ.
PMID: 16558094
Infect Immun. 1974 Nov;10(5):1084-90. doi: 10.1128/iai.10.5.1084-1090.1974.

The immunoglobulin classes of antibodies to Campylobacter (Vibrio) fetus in cervicovaginal mucus (CVM) were determined by the indirect fluorescent antibody test at sequential periods, since the order of class appearance has not been established for specific secretory immune responses....

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Corbeil LB, Duncan JR, Schurig GG, et al. Bovine venereal vibriosis: variations in immunoglobulin class of antibodies in genital secretions and serum. Infect Immun. 1974;10(5):1084-90doi: 10.1128/iai.10.5.1084-1090.1974.
Corbeil, L. B., Duncan, J. R., Schurig, G. G., Hall, C. E., & Winter, A. J. (1974). Bovine venereal vibriosis: variations in immunoglobulin class of antibodies in genital secretions and serum. Infection and immunity, 10(5), 1084-90. https://doi.org/10.1128/iai.10.5.1084-1090.1974
Corbeil, L B, et al. "Bovine venereal vibriosis: variations in immunoglobulin class of antibodies in genital secretions and serum." Infection and immunity vol. 10,5 (1974): 1084-90. doi: https://doi.org/10.1128/iai.10.5.1084-1090.1974
Corbeil LB, Duncan JR, Schurig GG, Hall CE, Winter AJ. Bovine venereal vibriosis: variations in immunoglobulin class of antibodies in genital secretions and serum. Infect Immun. 1974 Nov;10(5):1084-90. doi: 10.1128/iai.10.5.1084-1090.1974. PMID: 16558094; PMCID: PMC423066.
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Analysis of megadalton ions using cryodetection MALDI time-of-flight mass spectrometry.

Analytical chemistry

Wenzel RJ, Matter U, Schultheis L, Zenobi R.
PMID: 16013843
Anal Chem. 2005 Jul 15;77(14):4329-37. doi: 10.1021/ac0482054.

Presented are initial results from the first commercially available matrix-assisted laser desorption/ionization time-of-flight mass spectrometer specifically designed for the sensitive detection of very high mass ions (macromizer, Comet AG). This new instrument utilizes a 16-element superconducting tunnel junction detector...

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Wenzel RJ, Matter U, Schultheis L, et al. Analysis of megadalton ions using cryodetection MALDI time-of-flight mass spectrometry. Anal Chem. 2005;77(14):4329-37doi: 10.1021/ac0482054.
Wenzel, R. J., Matter, U., Schultheis, L., & Zenobi, R. (2005). Analysis of megadalton ions using cryodetection MALDI time-of-flight mass spectrometry. Analytical chemistry, 77(14), 4329-37. https://doi.org/10.1021/ac0482054
Wenzel, Ryan J, et al. "Analysis of megadalton ions using cryodetection MALDI time-of-flight mass spectrometry." Analytical chemistry vol. 77,14 (2005): 4329-37. doi: https://doi.org/10.1021/ac0482054
Wenzel RJ, Matter U, Schultheis L, Zenobi R. Analysis of megadalton ions using cryodetection MALDI time-of-flight mass spectrometry. Anal Chem. 2005 Jul 15;77(14):4329-37. doi: 10.1021/ac0482054. PMID: 16013843.
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Laboratory diagnosis of mumps in a partially immunized population: The Nova Scotia experience.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

Hatchette T, Davidson R, Clay S, Pettipas J, Leblanc J, Sarwal S, Smieja M, Forward K.
PMID: 21119794
Can J Infect Dis Med Microbiol. 2009;20(4):e157-62. doi: 10.1155/2009/493275.

BACKGROUND: In 2007, Atlantic Canada experienced a large outbreak of mumps predominately in university students who had received a single dose of measles, mumps and rubella vaccine. The present study describes the performance characteristics of reverse transcriptase polymerase chain...

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Hatchette T, Davidson R, Clay S, et al. Laboratory diagnosis of mumps in a partially immunized population: The Nova Scotia experience. Can J Infect Dis Med Microbiol. 2009;20(4):e157-62doi: 10.1155/2009/493275.
Hatchette, T., Davidson, R., Clay, S., Pettipas, J., Leblanc, J., Sarwal, S., Smieja, M., & Forward, K. (2009). Laboratory diagnosis of mumps in a partially immunized population: The Nova Scotia experience. The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 20(4), e157-62. https://doi.org/10.1155/2009/493275
Hatchette, Tf, et al. "Laboratory diagnosis of mumps in a partially immunized population: The Nova Scotia experience." The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale vol. 20,4 (2009): e157-62. doi: https://doi.org/10.1155/2009/493275
Hatchette T, Davidson R, Clay S, Pettipas J, Leblanc J, Sarwal S, Smieja M, Forward K. Laboratory diagnosis of mumps in a partially immunized population: The Nova Scotia experience. Can J Infect Dis Med Microbiol. 2009;20(4):e157-62. doi: 10.1155/2009/493275. PMID: 21119794; PMCID: PMC2807259.
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An unusual case of atypical lymphocytosis.

Sultan Qaboos University medical journal

Venugopal S, George J, Al-Harthy SS.
PMID: 21748084
Sultan Qaboos Univ Med J. 2008 Nov;8(3):353-5.

Atypical lymphocytosis due to infections is classically seen in viral and chronic bacterial infections. A four year old boy with acute streptococcal infection presented at Al-Nahdha Hospital, Muscat, Oman, with follicular tonsillitis and bilateral cervical lymphadenitis. The blood film...

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Venugopal S, George J, Al-Harthy SS. An unusual case of atypical lymphocytosis. Sultan Qaboos Univ Med J. 2008;8(3):353-5
Venugopal, S., George, J., & Al-Harthy, S. S. (2008). An unusual case of atypical lymphocytosis. Sultan Qaboos University medical journal, 8(3), 353-5.
Venugopal, Suresh, et al. "An unusual case of atypical lymphocytosis." Sultan Qaboos University medical journal vol. 8,3 (2008): 353-5.
Venugopal S, George J, Al-Harthy SS. An unusual case of atypical lymphocytosis. Sultan Qaboos Univ Med J. 2008 Nov;8(3):353-5. PMID: 21748084; PMCID: PMC3074833.
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Power of selective genotyping in genome-wide association studies of quantitative traits.

BMC proceedings

Xing C, Xing G.
PMID: 20018013
BMC Proc. 2009 Dec 15;3:S23. doi: 10.1186/1753-6561-3-s7-s23.

The selective genotyping approach in quantitative genetics means genotyping only individuals with extreme phenotypes. This approach is considered an efficient way to perform gene mapping, and can be applied in both linkage and association studies. Selective genotyping in association...

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Xing C, Xing G. Power of selective genotyping in genome-wide association studies of quantitative traits. BMC Proc. 2009;3:S23doi: 10.1186/1753-6561-3-s7-s23.
Xing, C., & Xing, G. (2009). Power of selective genotyping in genome-wide association studies of quantitative traits. BMC proceedings, 3S23. https://doi.org/10.1186/1753-6561-3-s7-s23
Xing, Chao, and Xing, Guan. "Power of selective genotyping in genome-wide association studies of quantitative traits." BMC proceedings vol. 3 (2009): S23. doi: https://doi.org/10.1186/1753-6561-3-s7-s23
Xing C, Xing G. Power of selective genotyping in genome-wide association studies of quantitative traits. BMC Proc. 2009 Dec 15;3:S23. doi: 10.1186/1753-6561-3-s7-s23. PMID: 20018013; PMCID: PMC2795920.
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Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child.

Clinical ophthalmology (Auckland, N.Z.)

Gallego-Pinazo R, Harto M, Garcia-Medina JJ, Serra I, España E, Pinazo-Duran MD.
PMID: 19668736
Clin Ophthalmol. 2008 Jun;2(2):451-5. doi: 10.2147/opth.s1757.

OBJECTIVE: To describe a case of bilateral acute retinal necrosis syndrome (ARNS) in a 5-year-old boy.METHOD: A retrospective, interventional case is described in one child attending the pediatric ophthalmology section, complaining of sudden bilateral red eye and haze-impaired vision....

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Gallego-Pinazo R, Harto M, Garcia-Medina JJ, et al. Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child. Clin Ophthalmol. 2008;2(2):451-5doi: 10.2147/opth.s1757.
Gallego-Pinazo, R., Harto, M., Garcia-Medina, J. J., Serra, I., España, E., & Pinazo-Duran, M. D. (2008). Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child. Clinical ophthalmology (Auckland, N.Z.), 2(2), 451-5. https://doi.org/10.2147/opth.s1757
Gallego-Pinazo, Roberto, et al. "Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child." Clinical ophthalmology (Auckland, N.Z.) vol. 2,2 (2008): 451-5. doi: https://doi.org/10.2147/opth.s1757
Gallego-Pinazo R, Harto M, Garcia-Medina JJ, Serra I, España E, Pinazo-Duran MD. Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child. Clin Ophthalmol. 2008 Jun;2(2):451-5. doi: 10.2147/opth.s1757. PMID: 19668736; PMCID: PMC2693969.
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Preventative and therapeutic vaccination to combat an experimental autoimmune kidney disease.

Biologics : targets & therapy

Barabas AZ, Cole CD, Barabas AD, Lafreniere R.
PMID: 19707349
Biologics. 2007 Mar;1(1):59-68.

We describe a new vaccination method called modified vaccination technique (MVT). The technique is able to achieve downregulation of pathogenic autoimmune events leading to a chronic progressive disorder in rats called slowly progressive Heymann nephritis. Downregulation of immunopathological events...

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Barabas AZ, Cole CD, Barabas AD, et al. Preventative and therapeutic vaccination to combat an experimental autoimmune kidney disease. Biologics. 2007;1(1):59-68
Barabas, A. Z., Cole, C. D., Barabas, A. D., & Lafreniere, R. (2007). Preventative and therapeutic vaccination to combat an experimental autoimmune kidney disease. Biologics : targets & therapy, 1(1), 59-68.
Barabas, Arpad Z, et al. "Preventative and therapeutic vaccination to combat an experimental autoimmune kidney disease." Biologics : targets & therapy vol. 1,1 (2007): 59-68.
Barabas AZ, Cole CD, Barabas AD, Lafreniere R. Preventative and therapeutic vaccination to combat an experimental autoimmune kidney disease. Biologics. 2007 Mar;1(1):59-68. PMID: 19707349; PMCID: PMC2721341.
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Showing 13 to 24 of 582 entries