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Dengue Virus Serotype 1 Conformational Dynamics Confers Virus Strain-Dependent Patterns of Neutralization by Polyclonal Sera.

Journal of virology

VanBlargan LA, Milutinovic PS, Goo L, DeMaso CR, Durbin AP, Whitehead SS, Pierson TC, Dowd KA.
PMID: 34549976
J Virol. 2021 Nov 09;95(23):e0095621. doi: 10.1128/JVI.00956-21. Epub 2021 Sep 22.

Dengue virus cocirculates globally as four serotypes (DENV1 to -4) that vary up to 40% at the amino acid level. Viral strains within a serotype further cluster into multiple genotypes. Eliciting a protective tetravalent neutralizing antibody response is a...

Cite
VanBlargan LA, Milutinovic PS, Goo L, et al. Dengue Virus Serotype 1 Conformational Dynamics Confers Virus Strain-Dependent Patterns of Neutralization by Polyclonal Sera. J Virol. 2021;95(23):e0095621doi: 10.1128/JVI.00956-21.
VanBlargan, L. A., Milutinovic, P. S., Goo, L., DeMaso, C. R., Durbin, A. P., Whitehead, S. S., Pierson, T. C., & Dowd, K. A. (2021). Dengue Virus Serotype 1 Conformational Dynamics Confers Virus Strain-Dependent Patterns of Neutralization by Polyclonal Sera. Journal of virology, 95(23), e0095621. https://doi.org/10.1128/JVI.00956-21
VanBlargan, Laura A, et al. "Dengue Virus Serotype 1 Conformational Dynamics Confers Virus Strain-Dependent Patterns of Neutralization by Polyclonal Sera." Journal of virology vol. 95,23 (2021): e0095621. doi: https://doi.org/10.1128/JVI.00956-21
VanBlargan LA, Milutinovic PS, Goo L, DeMaso CR, Durbin AP, Whitehead SS, Pierson TC, Dowd KA. Dengue Virus Serotype 1 Conformational Dynamics Confers Virus Strain-Dependent Patterns of Neutralization by Polyclonal Sera. J Virol. 2021 Nov 09;95(23):e0095621. doi: 10.1128/JVI.00956-21. Epub 2021 Sep 22. PMID: 34549976; PMCID: PMC8577358.
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Implications of a highly divergent dengue virus strain for cross-neutralization, protection, and vaccine immunity.

Cell host & microbe

Chen RE, Smith BK, Errico JM, Gordon DN, Winkler ES, VanBlargan LA, Desai C, Handley SA, Dowd KA, Amaro-Carambot E, Cardosa MJ, Sariol CA, Kallas EG, Sékaly RP, Vasilakis N, Fremont DH, Whitehead SS, Pierson TC, Diamond MS.
PMID: 34610295
Cell Host Microbe. 2021 Nov 10;29(11):1634-1648.e5. doi: 10.1016/j.chom.2021.09.006. Epub 2021 Oct 04.

Although divergent dengue viruses (DENVs) have been isolated in insects, nonhuman primates, and humans, their relationships to the four canonical serotypes (DENV 1-4) are poorly understood. One virus isolated from a dengue patient, DKE-121, falls between genotype and serotype...

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Chen RE, Smith BK, Errico JM, et al. Implications of a highly divergent dengue virus strain for cross-neutralization, protection, and vaccine immunity. Cell Host Microbe. 2021;29(11):1634-1648.e5doi: 10.1016/j.chom.2021.09.006.
Chen, R. E., Smith, B. K., Errico, J. M., Gordon, D. N., Winkler, E. S., VanBlargan, L. A., Desai, C., Handley, S. A., Dowd, K. A., Amaro-Carambot, E., Cardosa, M. J., Sariol, C. A., Kallas, E. G., Sékaly, R. P., Vasilakis, N., Fremont, D. H., Whitehead, S. S., Pierson, T. C., & Diamond, M. S. (2021). Implications of a highly divergent dengue virus strain for cross-neutralization, protection, and vaccine immunity. Cell host & microbe, 29(11), 1634-1648.e5. https://doi.org/10.1016/j.chom.2021.09.006
Chen, Rita E, et al. "Implications of a highly divergent dengue virus strain for cross-neutralization, protection, and vaccine immunity." Cell host & microbe vol. 29,11 (2021): 1634-1648.e5. doi: https://doi.org/10.1016/j.chom.2021.09.006
Chen RE, Smith BK, Errico JM, Gordon DN, Winkler ES, VanBlargan LA, Desai C, Handley SA, Dowd KA, Amaro-Carambot E, Cardosa MJ, Sariol CA, Kallas EG, Sékaly RP, Vasilakis N, Fremont DH, Whitehead SS, Pierson TC, Diamond MS. Implications of a highly divergent dengue virus strain for cross-neutralization, protection, and vaccine immunity. Cell Host Microbe. 2021 Nov 10;29(11):1634-1648.e5. doi: 10.1016/j.chom.2021.09.006. Epub 2021 Oct 04. PMID: 34610295; PMCID: PMC8595868.
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Comparison of the neutralizing activities of antibodies in clinical sera against both Sabin and wild-type polio pseudoviruses.

Journal of virological methods

Liu S, Lu W, Ma S, Guo H, Zhang Z, Li X.
PMID: 34826519
J Virol Methods. 2021 Nov 24;300:114376. doi: 10.1016/j.jviromet.2021.114376. Epub 2021 Nov 24.

The cost-effectiveness of the Sabin inactivated poliovirus vaccine derived from the Sabin strains (S-IPV) and its reduced biosecurity risks during its manufacture make it the vaccine of choice over the IPVs derived from wild-type polioviruses. However, it is difficult...

Cite
Liu S, Lu W, Ma S, et al. Comparison of the neutralizing activities of antibodies in clinical sera against both Sabin and wild-type polio pseudoviruses. J Virol Methods. 2021;300:114376doi: 10.1016/j.jviromet.2021.114376.
Liu, S., Lu, W., Ma, S., Guo, H., Zhang, Z., & Li, X. (2021). Comparison of the neutralizing activities of antibodies in clinical sera against both Sabin and wild-type polio pseudoviruses. Journal of virological methods, 300114376. https://doi.org/10.1016/j.jviromet.2021.114376
Liu, Shaohua, et al. "Comparison of the neutralizing activities of antibodies in clinical sera against both Sabin and wild-type polio pseudoviruses." Journal of virological methods vol. 300 (2021): 114376. doi: https://doi.org/10.1016/j.jviromet.2021.114376
Liu S, Lu W, Ma S, Guo H, Zhang Z, Li X. Comparison of the neutralizing activities of antibodies in clinical sera against both Sabin and wild-type polio pseudoviruses. J Virol Methods. 2021 Nov 24;300:114376. doi: 10.1016/j.jviromet.2021.114376. Epub 2021 Nov 24. PMID: 34826519.
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Showing 181 to 183 of 183 entries