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Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice.

Indian journal of pharmacology

Kumar A, Garg R, Gaur V, Kumar P.
PMID: 21713041
Indian J Pharmacol. 2011 May;43(3):324-9. doi: 10.4103/0253-7613.81506.

BACKGROUND AND OBJECTIVE: The present study was designed to elucidate the possible nitric oxide (NO) mechanism in the protective effect of antidepressants using mice model of chronic fatigue syndrome (CFS).MATERIALS AND METHODS: Male albino laca mice were forced to...

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Kumar A, Garg R, Gaur V, et al. Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice. Indian J Pharmacol. 2011;43(3):324-9doi: 10.4103/0253-7613.81506.
Kumar, A., Garg, R., Gaur, V., & Kumar, P. (2011). Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice. Indian journal of pharmacology, 43(3), 324-9. https://doi.org/10.4103/0253-7613.81506
Kumar, Anil, et al. "Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice." Indian journal of pharmacology vol. 43,3 (2011): 324-9. doi: https://doi.org/10.4103/0253-7613.81506
Kumar A, Garg R, Gaur V, Kumar P. Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice. Indian J Pharmacol. 2011 May;43(3):324-9. doi: 10.4103/0253-7613.81506. PMID: 21713041; PMCID: PMC3113388.
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Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice.

Ayu

Deole YS, Chavan SS, Ashok BK, Ravishankar B, Thakar AB, Chandola HM.
PMID: 22529654
Ayu. 2011 Jul;32(3):375-9. doi: 10.4103/0974-8520.93918.

In recent years, many Ayurvedic formulations are being researched to provide an effective antidepressant and anxiolytic drug in the field of psycho-pharmacology. The present study was planned to evaluate the anti-depressant and anxiolytic activity of Rasayana Ghana Tablet comprising...

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Deole YS, Chavan SS, Ashok BK, et al. Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice. Ayu. 2011;32(3):375-9doi: 10.4103/0974-8520.93918.
Deole, Y. S., Chavan, S. S., Ashok, B. K., Ravishankar, B., Thakar, A. B., & Chandola, H. M. (2011). Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice. Ayu, 32(3), 375-9. https://doi.org/10.4103/0974-8520.93918
Deole, Yogesh S, et al. "Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice." Ayu vol. 32,3 (2011): 375-9. doi: https://doi.org/10.4103/0974-8520.93918
Deole YS, Chavan SS, Ashok BK, Ravishankar B, Thakar AB, Chandola HM. Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice. Ayu. 2011 Jul;32(3):375-9. doi: 10.4103/0974-8520.93918. PMID: 22529654; PMCID: PMC3326886.
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Evaluation of protective effect of Aegle marmelos Corr. in an animal model of chronic fatigue syndrome.

Indian journal of pharmacology

Lalremruta V, Prasanna GS.
PMID: 22701245
Indian J Pharmacol. 2012 May;44(3):351-6. doi: 10.4103/0253-7613.96316.

OBJECTIVE: To evaluate ethanolic extract of leaves of Aegle marmelos in an experimental animal model of chronic fatigue syndrome for potential therapeutic benefit.MATERIALS AND METHODS: Age/weight-matched female Wistar albino rats were grouped into five groups. (Group I- V) (n...

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Lalremruta V, Prasanna GS. Evaluation of protective effect of Aegle marmelos Corr. in an animal model of chronic fatigue syndrome. Indian J Pharmacol. 2012;44(3):351-6doi: 10.4103/0253-7613.96316.
Lalremruta, V., & Prasanna, G. S. (2012). Evaluation of protective effect of Aegle marmelos Corr. in an animal model of chronic fatigue syndrome. Indian journal of pharmacology, 44(3), 351-6. https://doi.org/10.4103/0253-7613.96316
Lalremruta, Vanphawng, and Prasanna, Gurunath S. "Evaluation of protective effect of Aegle marmelos Corr. in an animal model of chronic fatigue syndrome." Indian journal of pharmacology vol. 44,3 (2012): 351-6. doi: https://doi.org/10.4103/0253-7613.96316
Lalremruta V, Prasanna GS. Evaluation of protective effect of Aegle marmelos Corr. in an animal model of chronic fatigue syndrome. Indian J Pharmacol. 2012 May;44(3):351-6. doi: 10.4103/0253-7613.96316. PMID: 22701245; PMCID: PMC3371458.
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Neurotoxicity of 1,2,3,4-tetrahydro-2-methyl-4,6,7-isoquinolinetriol (TMIQ) and effects on catecholamine homeostasis in SH-SY5Y cells.

Environmental toxicology and pharmacology

Willets JM, Lambert DG, Lunec J, Griffiths HR, Phillipson O.
PMID: 21781702
Environ Toxicol Pharmacol. 1996 Aug 15;2(1):59-68. doi: 10.1016/1382-6689(96)00030-0.

We have investigated the potential neurotoxicity of the catecholamine depleting agent 1,2,3,4-tetrahydro-2-methyl-4,6,7-isoquinolinetriol (TMIQ) in SH-SY5Y neuroblastoma cells. TMIQ induced a time and dose related inhibition of 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; thiazoyl blue (MTT) reduction and an increase in lactate dehydrogenase release....

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Willets JM, Lambert DG, Lunec J, et al. Neurotoxicity of 1,2,3,4-tetrahydro-2-methyl-4,6,7-isoquinolinetriol (TMIQ) and effects on catecholamine homeostasis in SH-SY5Y cells. Environ Toxicol Pharmacol. 1996;2(1):59-68doi: 10.1016/1382-6689(96)00030-0.
Willets, J. M., Lambert, D. G., Lunec, J., Griffiths, H. R., & Phillipson, O. (1996). Neurotoxicity of 1,2,3,4-tetrahydro-2-methyl-4,6,7-isoquinolinetriol (TMIQ) and effects on catecholamine homeostasis in SH-SY5Y cells. Environmental toxicology and pharmacology, 2(1), 59-68. https://doi.org/10.1016/1382-6689(96)00030-0
Willets, J M, et al. "Neurotoxicity of 1,2,3,4-tetrahydro-2-methyl-4,6,7-isoquinolinetriol (TMIQ) and effects on catecholamine homeostasis in SH-SY5Y cells." Environmental toxicology and pharmacology vol. 2,1 (1996): 59-68. doi: https://doi.org/10.1016/1382-6689(96)00030-0
Willets JM, Lambert DG, Lunec J, Griffiths HR, Phillipson O. Neurotoxicity of 1,2,3,4-tetrahydro-2-methyl-4,6,7-isoquinolinetriol (TMIQ) and effects on catecholamine homeostasis in SH-SY5Y cells. Environ Toxicol Pharmacol. 1996 Aug 15;2(1):59-68. doi: 10.1016/1382-6689(96)00030-0. PMID: 21781702.
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Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures.

Toxicology in vitro : an international journal published in association with BIBRA

Boelsterli UA, Bouis P, Donatsch P.
PMID: 20647077
Toxicol In Vitro. 1987;1(3):127-32. doi: 10.1016/0887-2333(87)90012-9.

Glycerolipid synthesis and secretion in rat hepatocyte monolayer cultures have been studied as possible endpoints in cytotoxicity assays. Ten psychotropic drugs of different structural classes were incubated with the hepatocytes at concentrations ranging from 10(-6)m to 5 x 10(-5)m...

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Boelsterli UA, Bouis P, Donatsch P. Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures. Toxicol In Vitro. 1987;1(3):127-32doi: 10.1016/0887-2333(87)90012-9.
Boelsterli, U. A., Bouis, P., & Donatsch, P. (1987). Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures. Toxicology in vitro : an international journal published in association with BIBRA, 1(3), 127-32. https://doi.org/10.1016/0887-2333(87)90012-9
Boelsterli, U A, et al. "Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures." Toxicology in vitro : an international journal published in association with BIBRA vol. 1,3 (1987): 127-32. doi: https://doi.org/10.1016/0887-2333(87)90012-9
Boelsterli UA, Bouis P, Donatsch P. Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures. Toxicol In Vitro. 1987;1(3):127-32. doi: 10.1016/0887-2333(87)90012-9. PMID: 20647077.
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Combined computational metabolite prediction and automated structure-based analysis of mass spectrometric data.

Toxicology mechanisms and methods

Stranz DD, Miao S, Campbell S, Maydwell G, Ekins S.
PMID: 20020918
Toxicol Mech Methods. 2008;18(2):243-50. doi: 10.1080/15376510701857189.

ABSTRACT As high-throughput technologies have developed in the pharmaceutical industry, the demand for identification of possible metabolites using predominantly liquid chromatographic/mass spectrometry-mass spectrometry/mass spectrometry (LC/MS-MS/MS) for a large number of molecules in drug discovery has also increased. In parallel,...

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Stranz DD, Miao S, Campbell S, et al. Combined computational metabolite prediction and automated structure-based analysis of mass spectrometric data. Toxicol Mech Methods. 2008;18(2):243-50doi: 10.1080/15376510701857189.
Stranz, D. D., Miao, S., Campbell, S., Maydwell, G., & Ekins, S. (2008). Combined computational metabolite prediction and automated structure-based analysis of mass spectrometric data. Toxicology mechanisms and methods, 18(2), 243-50. https://doi.org/10.1080/15376510701857189
Stranz, David D, et al. "Combined computational metabolite prediction and automated structure-based analysis of mass spectrometric data." Toxicology mechanisms and methods vol. 18,2 (2008): 243-50. doi: https://doi.org/10.1080/15376510701857189
Stranz DD, Miao S, Campbell S, Maydwell G, Ekins S. Combined computational metabolite prediction and automated structure-based analysis of mass spectrometric data. Toxicol Mech Methods. 2008;18(2):243-50. doi: 10.1080/15376510701857189. PMID: 20020918.
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Reduced cell survival and morphological alterations induced by three tricyclic antidepressants in human peripheral monocytes and lymphocytes and in cell lines derived from these cell types.

Toxicology in vitro : an international journal published in association with BIBRA

Hansson AL, Xia Z, Berglund MC, Bergstrand A, Depierre JW, Nässberger L.
PMID: 20654293
Toxicol In Vitro. 1997 Feb-Apr;11(1):21-31. doi: 10.1016/s0887-2333(97)00003-9.

Tricyclic antidepressant drugs are widely used for the treatment of manic-depressive disorders. As such compounds have been reported to give rise to myelin figures in lymphocytes in experimental animals, the effects of clomipramine (2.5-50 muM), imipramine (2.5-100 muM) and...

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Hansson AL, Xia Z, Berglund MC, et al. Reduced cell survival and morphological alterations induced by three tricyclic antidepressants in human peripheral monocytes and lymphocytes and in cell lines derived from these cell types. Toxicol In Vitro. 1997;11(1):21-31doi: 10.1016/s0887-2333(97)00003-9.
Hansson, A. L., Xia, Z., Berglund, M. C., Bergstrand, A., Depierre, J. W., & Nässberger, L. (1997). Reduced cell survival and morphological alterations induced by three tricyclic antidepressants in human peripheral monocytes and lymphocytes and in cell lines derived from these cell types. Toxicology in vitro : an international journal published in association with BIBRA, 11(1), 21-31. https://doi.org/10.1016/s0887-2333(97)00003-9
Hansson, A L, et al. "Reduced cell survival and morphological alterations induced by three tricyclic antidepressants in human peripheral monocytes and lymphocytes and in cell lines derived from these cell types." Toxicology in vitro : an international journal published in association with BIBRA vol. 11,1 (1997): 21-31. doi: https://doi.org/10.1016/s0887-2333(97)00003-9
Hansson AL, Xia Z, Berglund MC, Bergstrand A, Depierre JW, Nässberger L. Reduced cell survival and morphological alterations induced by three tricyclic antidepressants in human peripheral monocytes and lymphocytes and in cell lines derived from these cell types. Toxicol In Vitro. 1997 Feb-Apr;11(1):21-31. doi: 10.1016/s0887-2333(97)00003-9. PMID: 20654293.
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Enhanced Permeability of Etoposide across Everted Sacs of Rat Small Intestine by Vitamin E-TPGS.

Iranian journal of pharmaceutical research : IJPR

Parsa A, Saadati R, Abbasian Z, Azad Aramaki S, Dadashzadeh S.
PMID: 24250670
Iran J Pharm Res. 2013;12:37-46.

Etoposide, a widely used anticancer drug, exhibits low and variable oral bioavailability mainly because of being substrate for the efflux transporter, P-glycoprotein (P-gp). Therefore, the present study was aimed to investigate the effect of D-α-tocopherol polyethylene glycol 1000 succinate...

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Parsa A, Saadati R, Abbasian Z, et al. Enhanced Permeability of Etoposide across Everted Sacs of Rat Small Intestine by Vitamin E-TPGS. Iran J Pharm Res. 2013;12:37-46
Parsa, A., Saadati, R., Abbasian, Z., Azad Aramaki, S., & Dadashzadeh, S. (2013). Enhanced Permeability of Etoposide across Everted Sacs of Rat Small Intestine by Vitamin E-TPGS. Iranian journal of pharmaceutical research : IJPR, 1237-46.
Parsa, Abdolhamid, et al. "Enhanced Permeability of Etoposide across Everted Sacs of Rat Small Intestine by Vitamin E-TPGS." Iranian journal of pharmaceutical research : IJPR vol. 12 (2013): 37-46.
Parsa A, Saadati R, Abbasian Z, Azad Aramaki S, Dadashzadeh S. Enhanced Permeability of Etoposide across Everted Sacs of Rat Small Intestine by Vitamin E-TPGS. Iran J Pharm Res. 2013;12:37-46. PMID: 24250670; PMCID: PMC3813364.
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LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy.

Frontiers in neuroscience

Fitch TE, Benvenga MJ, Jesudason CD, Zink C, Vandergriff AB, Menezes MM, Schober DA, Rorick-Kehn LM.
PMID: 24478625
Front Neurosci. 2014 Jan 28;8:5. doi: 10.3389/fnins.2014.00005. eCollection 2014.

We describe a novel, potent and selective orexin-2 (OX2)/hypocretin-2 receptor antagonist with in vivo activity in an animal model predictive of antidepressant-like efficacy. N-biphenyl-2-yl-4-fluoro-N-(1H-imidazol-2-ylmethyl) benzenesulfonamide HCl (LSN2424100) binds with high affinity to recombinant human OX2 receptors (Ki = 4.5...

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Fitch TE, Benvenga MJ, Jesudason CD, et al. LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy. Front Neurosci. 2014;8:5doi: 10.3389/fnins.2014.00005.
Fitch, T. E., Benvenga, M. J., Jesudason, C. D., Zink, C., Vandergriff, A. B., Menezes, M. M., Schober, D. A., & Rorick-Kehn, L. M. (2014). LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy. Frontiers in neuroscience, 85. https://doi.org/10.3389/fnins.2014.00005
Fitch, Thomas E, et al. "LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy." Frontiers in neuroscience vol. 8 (2014): 5. doi: https://doi.org/10.3389/fnins.2014.00005
Fitch TE, Benvenga MJ, Jesudason CD, Zink C, Vandergriff AB, Menezes MM, Schober DA, Rorick-Kehn LM. LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy. Front Neurosci. 2014 Jan 28;8:5. doi: 10.3389/fnins.2014.00005. eCollection 2014. PMID: 24478625; PMCID: PMC3904085.
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Anti-anxiety and anti-depressant activities of Sarasvata choorna in experimental animals.

Ayu

Gupta K, Ashok BK, Ravishankar B, Thakar AB.
PMID: 22661860
Ayu. 2011 Oct;32(4):590-3. doi: 10.4103/0974-8520.96139.

The present study was undertaken to evaluate the anxiolytic and anti-depressant activity of Sarasvata choorna. The anxiolytic activity was evaluated in elevated plus maze (EPM) and the anti-depressant activity was evaluated in forced swimming test (FST). The efficacy of...

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Gupta K, Ashok BK, Ravishankar B, et al. Anti-anxiety and anti-depressant activities of Sarasvata choorna in experimental animals. Ayu. 2011;32(4):590-3doi: 10.4103/0974-8520.96139.
Gupta, K., Ashok, B. K., Ravishankar, B., & Thakar, A. B. (2011). Anti-anxiety and anti-depressant activities of Sarasvata choorna in experimental animals. Ayu, 32(4), 590-3. https://doi.org/10.4103/0974-8520.96139
Gupta, Kshama, et al. "Anti-anxiety and anti-depressant activities of Sarasvata choorna in experimental animals." Ayu vol. 32,4 (2011): 590-3. doi: https://doi.org/10.4103/0974-8520.96139
Gupta K, Ashok BK, Ravishankar B, Thakar AB. Anti-anxiety and anti-depressant activities of Sarasvata choorna in experimental animals. Ayu. 2011 Oct;32(4):590-3. doi: 10.4103/0974-8520.96139. PMID: 22661860; PMCID: PMC3361941.
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Effect of imipramine and ect on platelet mao activity in depressives.

Indian journal of psychiatry

Trivedi JK, Singh RP, Lal N, Viswanathan PN, Kumar S.
PMID: 21927372
Indian J Psychiatry. 1989 Apr;31(2):139-43.

Platelet monoamine Oxidase (MAO) activity was estimated in 30 depressed patients treated with Imipramine or EGT over a period of 5 weeks and pretreatment and post treatment values were compared. Imipramine and ECT caused significant reduction of platelet MAO,...

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Trivedi JK, Singh RP, Lal N, et al. Effect of imipramine and ect on platelet mao activity in depressives. Indian J Psychiatry. 1989;31(2):139-43
Trivedi, J. K., Singh, R. P., Lal, N., Viswanathan, P. N., & Kumar, S. (1989). Effect of imipramine and ect on platelet mao activity in depressives. Indian journal of psychiatry, 31(2), 139-43.
Trivedi, J K, et al. "Effect of imipramine and ect on platelet mao activity in depressives." Indian journal of psychiatry vol. 31,2 (1989): 139-43.
Trivedi JK, Singh RP, Lal N, Viswanathan PN, Kumar S. Effect of imipramine and ect on platelet mao activity in depressives. Indian J Psychiatry. 1989 Apr;31(2):139-43. PMID: 21927372; PMCID: PMC2991675.
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A comparative study of dothiepin (prothiaden) and imipramine in depression.

Indian journal of psychiatry

Vyas JN, Sharma P, Singhal AK, Agarwal S.
PMID: 21927374
Indian J Psychiatry. 1989 Apr;31(2):151-6.

In a single-blind, randomised, parallel-group study comparing the efficacy and tolerability of dothiepin (50-150 mg per day) and imipramine (50-150 mg per day) for 6 weeks, involving 60 adult patients with depression, it was observed that dothiepin was comparable...

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Vyas JN, Sharma P, Singhal AK, et al. A comparative study of dothiepin (prothiaden) and imipramine in depression. Indian J Psychiatry. 1989;31(2):151-6
Vyas, J. N., Sharma, P., Singhal, A. K., & Agarwal, S. (1989). A comparative study of dothiepin (prothiaden) and imipramine in depression. Indian journal of psychiatry, 31(2), 151-6.
Vyas, J N, et al. "A comparative study of dothiepin (prothiaden) and imipramine in depression." Indian journal of psychiatry vol. 31,2 (1989): 151-6.
Vyas JN, Sharma P, Singhal AK, Agarwal S. A comparative study of dothiepin (prothiaden) and imipramine in depression. Indian J Psychiatry. 1989 Apr;31(2):151-6. PMID: 21927374; PMCID: PMC2991677.
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Showing 25 to 36 of 374 entries