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Showing 13 to 24 of 374 entries
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Possible Mode of Antidepressive Action of Imipramine.

Science (New York, N.Y.)

Stein L, Seifter J.
PMID: 17798819
Science. 1961 Jul 28;134(3474):286-7. doi: 10.1126/science.134.3474.286.

Imipramine augmented and prolonged methamphetamine-induced increases in the rate of responding of rats working for "rewarding" hypothalamic and midbrain stimulation. In contrast, chlorpromazine antagonized the effects of methamphetamine on self-stimulation. These opposite psychopharmacological effects are consistent with the different...

Depression in COPD--management and quality of life considerations.

International journal of chronic obstructive pulmonary disease

Stage KB, Middelboe T, Stage TB, Sørensen CH.
PMID: 18046868
Int J Chron Obstruct Pulmon Dis. 2006;1(3):315-20. doi: 10.2147/copd.2006.1.3.315.

Depression is common in COPD patients. Around 40% are affected by severe depressive symptoms or clinical depression. It is not easy to diagnose depression in COPD patients because of overlapping symptoms between COPD and depression. However, the six-item Hamilton...

School phobia: controlled imipramine treatment.

California medicine

Gittelman-Klein R, Klein DF.
PMID: 18730587
Calif Med. 1971 Sep;115(3):42.

No abstract available.

Bipolar disorder: involvement of signaling cascades and AMPA receptor trafficking at synapses.

Neuron glia biology

Du J, Quiroz J, Yuan P, Zarate C, Manji HK.
PMID: 18634600
Neuron Glia Biol. 2004 Aug;1(3):231-43. doi: 10.1017/S1740925X05000098.

There is increasing evidence that severe mood disorders are associated with impairment of structural plasticity and cellular resilience. Cumulative data demonstrate that mood stabilizers regulate intracellular signaling cascades, including protein kinase C (PKC), PKA, mitogen-activated protein (MAP) kinase, glycogen...

Antinociceptive efficacy of antidepressants: assessment of five antidepressants and four monoamine receptors in rats.

Journal of anesthesia

Otsuka N, Kiuchi Y, Yokogawa F, Masuda Y, Oguchi K, Hosoyamada A.
PMID: 14566514
J Anesth. 2001;15(3):154-8. doi: 10.1007/s005400170018.

PURPOSE: For assessment of the antinociceptive potency of antidepressants, we compared the antinociceptive effects of serotonin selective reuptake inhibitors (SSRIs) and classical tricyclic antidepressants (TCAs) in rats. We also attempted to elucidate the monoamine receptor subtypes predominantly involved in...

Differential pulse voltammetry for ion transfer at liquid membranes with two polarized interfaces.

Analytical chemistry

Molina A, Serna C, Ortuño JA, Gonzalez J, Torralba E, Gil A.
PMID: 19402678
Anal Chem. 2009 Jun 01;81(11):4220-5. doi: 10.1021/ac802503b.

A simple analytical expression for the response of the double-pulse technique differential pulse voltammetry (DPV) corresponding to ion transfer processes in systems with two liquid/liquid polarizable interfaces has been deduced. This expression predicts lower and wider curves than those...

A double-blind comparison of tianeptine, imipramine and placebo in the treatment of major depressive episodes.

European psychiatry : the journal of the Association of European Psychiatrists

Cassano GB, Heinze G, Lôo H, Mendlewicz J, Sousa MP.
PMID: 19698461
Eur Psychiatry. 1996;11(5):254-9. doi: 10.1016/0924-9338(96)82332-7.

In the course of the international development of tianeptine (T), depressed patients were recruited by 18 centres from Belgium, Italy, Mexico, Portugal, Spain and Switzerland in a double-blind parallel group study versus placebo (P) and imipramine (I). Efficacy and...

Uptake of 5-hydroxytryptamine by platelets.

British journal of pharmacology and chemotherapy

Stacey RS.
PMID: 19108152
Br J Pharmacol Chemother. 1961 Jun;16(3):284-95. doi: 10.1111/j.1476-5381.1961.tb01087.x.

Human blood platelets were incubated with 5-hydroxytryptamine and with tryptamine and the uptake of each amine measured. The uptake of tryptamine, unlike that of 5-hydroxytryptamine, was linearly related to the concentration of the amine in the surrounding fluid, was...

Simultaneous spectrophotometric estimation of imipramine hydrochloride and chlordiazepoxide in tablets.

Indian journal of pharmaceutical sciences

Patel S, Patel NJ, Patel SA.
PMID: 20502561
Indian J Pharm Sci. 2009 Jul;71(4):468-72. doi: 10.4103/0250-474X.57304.

A binary mixture of imipramine HCl and chlordiazepoxide was determined by three different spectrophotometric methods. The first method involved determination of imipramine HCl and chlordiazepoxide using the simultaneous equations and the second method involved absorbance ratio method. Imipramine has...

Micellar electrokinetic chromatographic study of the separation of an aromatase inhibitor and a tryciclic antidepressant in the breast cancer treatment.

Analytical chemistry insights

Flores JR, Salcedo AM, Fernández LM.
PMID: 19609393
Anal Chem Insights. 2008 Aug 13;3:91-101. doi: 10.4137/aci.s939.

Micellar electrokinetic chromatography (MEKC) was investigated for the simultaneous determination of letrozole, imipramine and their metabolites in human urine samples over a concentration range of therapeutic interest. Experimental parameters such as pH of the running electrolyte, sodium dodecylsulphate (SDS)...

Repeated treatment with antidepressant drugs and/or electroconvulsive shock (ECS) does not affect the quinpirole-induced elevation of the serum corticosterone concentration in rats.

Journal of psychopharmacology (Oxford, England)

Przegalinski E, Budziszewska B, Blaszczynska E.
PMID: 22281848
J Psychopharmacol. 1990 Jan;4(4):198-203. doi: 10.1177/026988119000400403.

The selective dopamine D2 receptor agonist quinpirole (0.03-1 mg/kg intra peritoneally) increased dose-dependently the serum corticosterone level in rats. The effect of the maximum dose of quinpirole (0.3 mg/kg intraperitoneally) was antagonized in a dose- dependent manner by the...

Amine handling properties of human carcinoid tumour cells in tissue culture.

Neurochemistry international

Wängberg B, Ahlman H, Nilsson O, Haglid K, Denney RM, Dahlström A.
PMID: 20504634
Neurochem Int. 1990;17(2):331-41. doi: 10.1016/0197-0186(90)90156-n.

Carcinoid tumour tissue from two patients was removed from lymph node metastases during surgery. Under sterile conditions the cells were prepared for tissue culture, and grew in clusters for a period of 3-4 weeks. Using immunofluorescence the neoplastic cells...

Showing 13 to 24 of 374 entries