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Showing 37 to 42 of 42 entries
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Nitric oxide enhances inhibitory synaptic transmission and neuronal excitability in Guinea-pig submucous plexus.

Frontiers in neuroscience

Bornstein JC, Marks KA, Foong JP, Gwynne RM, Wang ZH.
PMID: 20589236
Front Neurosci. 2010 May 21;4:30. doi: 10.3389/fnins.2010.00030.

Varicosities immunoreactive for nitric oxide synthase (NOS) make synaptic connections with submucosal neurons in the guinea-pig small intestine, but the effects of nitric oxide (NO) on these neurons are unknown. We used intracellular recording to characterize effects of sodium...

Efaroxan (RX 821037) is a potent and selective ?(2)-adrenoceptor antagonist in human frontal cortex membranes.

Neurochemistry international

de Vos H, de Backer JP, Vauquelin G.
PMID: 20504687
Neurochem Int. 1991;18(1):137-40. doi: 10.1016/0197-0186(91)90047-h.

The antagonist [(3)H]idazoxan binds with comparable affinity to ?(2) adrenergic receptors and to non-adrenergic "idazoxan sites" in human frontal cortex membranes (K(D) = 23 and 28 nM). RX 811033, the 2-ethyl derivative of idazoxan, displays about equal affinity for...

Effects and After-Effects of Idazoxan On Mood, Memory and Attention: Smith AP, Glue P, Wilson, S and Nutt DJ Health Psychology Research Unit, UWCC, and Reckitt & Colman Psychopharmacology Unit, Bristol.

Journal of psychopharmacology (Oxford, England)

[No authors listed]
PMID: 22291281
J Psychopharmacol. 1992 Jan;6(1):116. doi: 10.1177/026988119200600153.

No abstract available.

Effects of Idazoxan and Clonidine On Saccadic Eye Movements in Man: Glue P, White E, Wilson S, Ball D, and Nutt DJ. Reckitt and Colman Psychopharmacology Unit, School of Medical Sciences, Bristol BS8 1TD.

Journal of psychopharmacology (Oxford, England)

[No authors listed]
PMID: 22291252
J Psychopharmacol. 1992 Jan;6(1):102. doi: 10.1177/026988119200600124.

No abstract available.

The effects and after effects of the α2-adrenoceptor antagonist idazoxan on mood, memory and attention in normal volunteers.

Journal of psychopharmacology (Oxford, England)

Smith AP, Wilson SJ, Glue P, Nutt DJ.
PMID: 22291383
J Psychopharmacol. 1992 Jan;6(3):376-81. doi: 10.1177/026988119200600306.

Idazoxan, an α( 2)-adrenoceptor antagonist, is an effective antidepressant with a mode of action different from that of conventional antidepressants. As it is used as an antidepressant it is important to know whether there are any unwanted CNS side...

Alpha1-adrenergic antagonists block 6-nitrodopamine contractions on the rat isolated epididymal vas deferens.

European journal of pharmacology

Britto-Júnior J, Ribeiro A, Ximenes L, Lima AT, Jacintho FF, Fregonesi A, Mónica FZ, Antunes E, De Nucci G.
PMID: 34951979
Eur J Pharmacol. 2021 Dec 22;915:174716. doi: 10.1016/j.ejphar.2021.174716. Epub 2021 Dec 22.

6-nitrodopamine (6-ND) is released from rat isolated vas deferens and modulates electrical-field stimulation (EFS) contractions of the rat isolated epididymal vas deferens (RIEVD) via a specific receptor which is blocked by tricyclic antidepressants. Here, the effects of selective α

Showing 37 to 42 of 42 entries