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Showing 25 to 36 of 42 entries
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α2-Adrenoceptor Control of Cortisol and Acth in Normal Volunteers: Effects of Idazoxan: Glue P, Wilson SJ, and Nutt DJ. Reckitt and Colman Psychopharmacology Unit, School of Medical Sciences, University Walk, Bristol BS8 1TD.

Journal of psychopharmacology (Oxford, England)

[No authors listed]
PMID: 22291260
J Psychopharmacol. 1992 Jan;6(1):106. doi: 10.1177/026988119200600132.

No abstract available.

Discriminative stimulus properties of ethoxy idazoxan.

Journal of psychopharmacology (Oxford, England)

Jordan S, Jackson HC, Nutt DJ, Handley SL.
PMID: 22297762
J Psychopharmacol. 1995 Jan;9(3):228-33. doi: 10.1177/026988119500900305.

The technique of drug discrimination was used to examine the ability of the highly selective α(2)-adrenoceptor antagonist ethoxy idazoxan, which has negligible affinity for α( 1)-adrenoceptors or I(2) imidazoline receptors, to produce an interoceptive discriminable stimulus or cue in...

Effect of bee venom acupuncture on oxaliplatin-induced cold allodynia in rats.

Evidence-based complementary and alternative medicine : eCAM

Lim BS, Moon HJ, Li DX, Gil M, Min JK, Lee G, Bae H, Kim SK, Min BI.
PMID: 24058370
Evid Based Complement Alternat Med. 2013;2013:369324. doi: 10.1155/2013/369324. Epub 2013 Aug 22.

Oxaliplatin, a chemotherapy drug, often leads to neuropathic cold allodynia after a single administration. Bee venom acupuncture (BVA) has been used in Korea to relieve various pain symptoms and is shown to have a potent antiallodynic effect in nerve-injured...

Activation of Spinal α2-Adrenoceptors Using Diluted Bee Venom Stimulation Reduces Cold Allodynia in Neuropathic Pain Rats.

Evidence-based complementary and alternative medicine : eCAM

Kang SY, Roh DH, Park JH, Lee HJ, Lee JH.
PMID: 22969830
Evid Based Complement Alternat Med. 2012;2012:784713. doi: 10.1155/2012/784713. Epub 2012 Aug 27.

Cold allodynia is an important distinctive feature of neuropathic pain. The present study examined whether single or repetitive treatment of diluted bee venom (DBV) reduced cold allodynia in sciatic nerve chronic constriction injury (CCI) rats and whether these effects...

The effects of xylazine and alpha-adrenoreceptor antagonists on bovine uterine contractility in vitro.

Theriogenology

Ko JC, Hsu WH, Evans LE.
PMID: 16726756
Theriogenology. 1990 Mar;33(3):601-11. doi: 10.1016/0093-691x(90)90537-4.

The effects of alpha-adrenoreceptor antagonists prazosin (alpha-1), yohimbine (alpha-2), and idazoxan (alpha-2) on xylazine-induced bovine uterine contractility were tested in vitro. Uterine strips from proestrous/estrous and diestrous cows were mounted in tissue baths containing Tyrode's solution. Changes in uterine...

Effects of idazoxan on 5-hydroxytryptamine-mediated behaviour in the mouse and rat.

Journal of psychopharmacology (Oxford, England)

Dickinson SL, Tulloch IF, Gadie B.
PMID: 22282554
J Psychopharmacol. 1991 Jan;5(3):187-95. doi: 10.1177/026988119100500302.

The α(2)-adrenoceptor antagonists idazoxan and RX811059 induced reciprocal forepaw treading, a component of the 5-HT-behavioural syndrome in rats. This response is independent of 'non-α(2)-adrenoceptor idazoxan binding sites' (NAIBS) at which RX811059 is inactive. Idazoxan pre-treatment, in rats, enhanced forepaw...

Systemic idazoxan impairs performance in a non-reversal shift test: implications for the role of the central noradrenergic systems in selective attention.

Journal of psychopharmacology (Oxford, England)

Rowe JB, Saunders JR, Durantou F, Robbins TW.
PMID: 22302944
J Psychopharmacol. 1996 Jan;10(3):188-94. doi: 10.1177/026988119601000303.

Two experiments examined the effect of pharmacological stimulation of the locus coeruleus in a non-reversal shift paradigm to test predictions concerning the role of the ceruleo-cortical noradrenergic system in processes of selective attention. Food-deprived rats were trained to make...

The effects of the α2-adrenoceptor antagonist idazoxan on sleep in normal volunteers.

Journal of psychopharmacology (Oxford, England)

Wilson SJ, Glue P, Nutt DJ.
PMID: 22282361
J Psychopharmacol. 1991 Jan;5(2):105-10. doi: 10.1177/026988119100500203.

The effects of idazoxan, a novel antidepressant that is a potent and selective α(2)-adrenoceptor antagonist, were studied on sleep. Twelve normal male volunteers had sleep recordings made using the Oxford ambulatory system (Medilog 9000) with subsequent analysis by automatic...

The Impact of α-Adrenoceptors in the Regulation of the Hypotonicity-Induced Increase in Duodenal Mucosal Permeability In Vivo.

Pharmaceutics

Sedin J, Dahlgren D, Sjöblom M, Nylander O.
PMID: 34959377
Pharmaceutics. 2021 Dec 06;13(12). doi: 10.3390/pharmaceutics13122096.

The duodenal mucosa is regularly exposed to a low osmolality, and recent experiments suggest that hypotonicity increases mucosal permeability in an osmolality-dependent manner. The aim was to examine whether the sympathetic nervous system, via action on α-adrenoceptors, affects the...

Precision Medicine in Patients with Differential Diabetic Phenotypes: Novel Opportunities from Network Medicine.

Current diabetes reviews

Napoli C, Benincasa G, Ellahham S.
PMID: 34951369
Curr Diabetes Rev. 2021 Dec 22; doi: 10.2174/1573399818666211222164400. Epub 2021 Dec 22.

INTRODUCTION: Diabetes mellitus (DM) comprises differential clinical phenotypes ranging from rare monogenic to common polygenic forms, such as type 1 (T1DM), type 2 (T2DM), and gestational diabetes, which are associated with cardiovascular complications. Also, the high-risk prediabetic state is...

Alpha1-adrenergic antagonists block 6-nitrodopamine contractions on the rat isolated epididymal vas deferens.

European journal of pharmacology

Britto-Júnior J, Ribeiro A, Ximenes L, Lima AT, Jacintho FF, Fregonesi A, Mónica FZ, Antunes E, De Nucci G.
PMID: 34951979
Eur J Pharmacol. 2022 Jan 15;915:174716. doi: 10.1016/j.ejphar.2021.174716. Epub 2021 Dec 22.

6-nitrodopamine (6-ND) is released from rat isolated vas deferens and modulates electrical-field stimulation (EFS) contractions of the rat isolated epididymal vas deferens (RIEVD) via a specific receptor which is blocked by tricyclic antidepressants. Here, the effects of selective α

Correction to Smith et al. (2013).

Behavioral neuroscience

Smith CD, Piasecki CC, Weera M, Olszewicz J, Lonstein JS.
PMID: 26214214
Behav Neurosci. 2015 Aug;129(4):411. doi: 10.1037/bne0000086.

Reports an error in "Noradrenergic alpha-2 receptor modulators in the ventral bed nucleus of the stria terminalis: Effects on anxiety behavior in postpartum and virgin female rats" by Carl D. Smith, Christopher C. Piasecki, Marcus Weera, Joshua Olszewicz and...

Showing 25 to 36 of 42 entries