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Isolation and Characterization of Leishmanial Adenine Aminohydrolase as a Drug Target.

Current computer-aided drug design

Butt F, Yasinzai M, Malik SI, Munir A.
PMID: 33290201
Curr Comput Aided Drug Des. 2021;17(7):905-915. doi: 10.2174/1573409916666201207194815.

BACKGROUND: Search for new drug targets is becoming imperative these days, given that marketed chemotherapeutic drugs have lost their efficacy against harmful agents because of adaptability to climatic changes and co-evolving vectors to new hosts. In the wake of...

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Butt F, Yasinzai M, Malik SI, et al. Isolation and Characterization of Leishmanial Adenine Aminohydrolase as a Drug Target. Curr Comput Aided Drug Des. 2021;17(7):905-915doi: 10.2174/1573409916666201207194815.
Butt, F., Yasinzai, M., Malik, S. I., & Munir, A. (2021). Isolation and Characterization of Leishmanial Adenine Aminohydrolase as a Drug Target. Current computer-aided drug design, 17(7), 905-915. https://doi.org/10.2174/1573409916666201207194815
Butt, Firdous, et al. "Isolation and Characterization of Leishmanial Adenine Aminohydrolase as a Drug Target." Current computer-aided drug design vol. 17,7 (2021): 905-915. doi: https://doi.org/10.2174/1573409916666201207194815
Butt F, Yasinzai M, Malik SI, Munir A. Isolation and Characterization of Leishmanial Adenine Aminohydrolase as a Drug Target. Curr Comput Aided Drug Des. 2021;17(7):905-915. doi: 10.2174/1573409916666201207194815. PMID: 33290201.
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Resistance exercise improves learning and memory and modulates hippocampal metabolomic profile in aged rats.

Neuroscience letters

Serra FT, Cardoso FDS, Petraconi N, Dos Santos JCC, Araujo BHS, Arida RM, Gomes da Silva S.
PMID: 34737021
Neurosci Lett. 2022 Jan 01;766:136322. doi: 10.1016/j.neulet.2021.136322. Epub 2021 Nov 02.

Physical activity has been considered an important non-medication intervention to preserve mnemonic processes during aging. However, how resistance exercise promotes such benefits remains unclear. A possible hypothesis is that brain-metabolic changes of regions responsible for memory consolidation is affected...

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Serra FT, Cardoso FDS, Petraconi N, et al. Resistance exercise improves learning and memory and modulates hippocampal metabolomic profile in aged rats. Neurosci Lett. 2021;766:136322doi: 10.1016/j.neulet.2021.136322.
Serra, F. T., Cardoso, F. D. S., Petraconi, N., Dos Santos, J. C. C., Araujo, B. H. S., Arida, R. M., & Gomes da Silva, S. (2022). Resistance exercise improves learning and memory and modulates hippocampal metabolomic profile in aged rats. Neuroscience letters, 766136322. https://doi.org/10.1016/j.neulet.2021.136322
Serra, Fernando Tadeu, et al. "Resistance exercise improves learning and memory and modulates hippocampal metabolomic profile in aged rats." Neuroscience letters vol. 766 (2022): 136322. doi: https://doi.org/10.1016/j.neulet.2021.136322
Serra FT, Cardoso FDS, Petraconi N, Dos Santos JCC, Araujo BHS, Arida RM, Gomes da Silva S. Resistance exercise improves learning and memory and modulates hippocampal metabolomic profile in aged rats. Neurosci Lett. 2022 Jan 01;766:136322. doi: 10.1016/j.neulet.2021.136322. Epub 2021 Nov 02. PMID: 34737021.
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Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†.

Biology of reproduction

Torres MA, Pedrosa AC, Novais FJ, Alkmin DV, Cooper BR, Yasui GS, Fukumasu H, Machaty Z, de Andrade AFC.
PMID: 34725678
Biol Reprod. 2022 Jan 13;106(1):213-226. doi: 10.1093/biolre/ioab200.

Holding at room temperature is the first step in most boar semen cryopreservation protocols. It is well accepted that a holding time (HT) of 24 h increases sperm cryotolerance. However, the effect of HT on ejaculates with different freezability...

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Torres MA, Pedrosa AC, Novais FJ, et al. Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†. Biol Reprod. 2022;106(1):213-226doi: 10.1093/biolre/ioab200.
Torres, M. A., Pedrosa, A. C., Novais, F. J., Alkmin, D. V., Cooper, B. R., Yasui, G. S., Fukumasu, H., Machaty, Z., & de Andrade, A. F. C. (2022). Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†. Biology of reproduction, 106(1), 213-226. https://doi.org/10.1093/biolre/ioab200
Torres, Mariana A, et al. "Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†." Biology of reproduction vol. 106,1 (2022): 213-226. doi: https://doi.org/10.1093/biolre/ioab200
Torres MA, Pedrosa AC, Novais FJ, Alkmin DV, Cooper BR, Yasui GS, Fukumasu H, Machaty Z, de Andrade AFC. Metabolomic signature of spermatozoa established during holding time is responsible for differences in boar sperm freezability†. Biol Reprod. 2022 Jan 13;106(1):213-226. doi: 10.1093/biolre/ioab200. PMID: 34725678.
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Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease.

Archives of medical research

Toledo-Ibelles P, Gutiérrez-Vidal R, Calixto-Tlacomulco S, Delgado-Coello B, Mas-Oliva J.
PMID: 33966916
Arch Med Res. 2021 Oct;52(7):692-702. doi: 10.1016/j.arcmed.2021.04.005. Epub 2021 May 06.

BACKGROUND: An elevated level of plasma uric acid has been widely recognized as a risk factor for non-alcoholic fatty liver disease (NAFLD), where oxidative stress and inflammation play an important role in the pathophysiology of the disease. Although the...

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Toledo-Ibelles P, Gutiérrez-Vidal R, Calixto-Tlacomulco S, et al. Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. Arch Med Res. 2021;52(7):692-702doi: 10.1016/j.arcmed.2021.04.005.
Toledo-Ibelles, P., Gutiérrez-Vidal, R., Calixto-Tlacomulco, S., Delgado-Coello, B., & Mas-Oliva, J. (2021). Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. Archives of medical research, 52(7), 692-702. https://doi.org/10.1016/j.arcmed.2021.04.005
Toledo-Ibelles, Paola, et al. "Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease." Archives of medical research vol. 52,7 (2021): 692-702. doi: https://doi.org/10.1016/j.arcmed.2021.04.005
Toledo-Ibelles P, Gutiérrez-Vidal R, Calixto-Tlacomulco S, Delgado-Coello B, Mas-Oliva J. Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. Arch Med Res. 2021 Oct;52(7):692-702. doi: 10.1016/j.arcmed.2021.04.005. Epub 2021 May 06. PMID: 33966916.
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Safety and Efficacy of Botulinum Toxin in the Treatment of Self-Biting Behavior in Lesch-Nyhan Disease.

Pediatric neurology

Garcia-Romero MDM, Torres RJ, Garcia-Puig J, Pascual-Pascual SI.
PMID: 34891105
Pediatr Neurol. 2021 Nov 01;127:6-10. doi: 10.1016/j.pediatrneurol.2021.10.018. Epub 2021 Nov 01.

BACKGROUND: Lesch-Nyhan disease (LND) is a disease of purine metabolism linked to chromosome X due to the absence or near-absence of enzyme hypoxanthine-guanine phosphoribosyltransferase. Patients with LND have a compulsive autoaggressive behavior that consists of self-mutilation by biting.METHODS: The...

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Garcia-Romero MDM, Torres RJ, Garcia-Puig J, et al. Safety and Efficacy of Botulinum Toxin in the Treatment of Self-Biting Behavior in Lesch-Nyhan Disease. Pediatr Neurol. 2021;127:6-10doi: 10.1016/j.pediatrneurol.2021.10.018.
Garcia-Romero, M. D. M., Torres, R. J., Garcia-Puig, J., & Pascual-Pascual, S. I. (2021). Safety and Efficacy of Botulinum Toxin in the Treatment of Self-Biting Behavior in Lesch-Nyhan Disease. Pediatric neurology, 1276-10. https://doi.org/10.1016/j.pediatrneurol.2021.10.018
Garcia-Romero, María Del Mar, et al. "Safety and Efficacy of Botulinum Toxin in the Treatment of Self-Biting Behavior in Lesch-Nyhan Disease." Pediatric neurology vol. 127 (2021): 6-10. doi: https://doi.org/10.1016/j.pediatrneurol.2021.10.018
Garcia-Romero MDM, Torres RJ, Garcia-Puig J, Pascual-Pascual SI. Safety and Efficacy of Botulinum Toxin in the Treatment of Self-Biting Behavior in Lesch-Nyhan Disease. Pediatr Neurol. 2021 Nov 01;127:6-10. doi: 10.1016/j.pediatrneurol.2021.10.018. Epub 2021 Nov 01. PMID: 34891105.
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Showing 445 to 449 of 449 entries