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Showing 25 to 36 of 73 entries
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Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes.

Journal of intensive care medicine

Koth AM, Chan T, Tjoeng YL, Watson RS, Dervan LA.
PMID: 34898312
J Intensive Care Med. 2021 Dec 13;8850666211066892. doi: 10.1177/08850666211066892. Epub 2021 Dec 13.

OBJECTIVE: Delirium is an increasingly recognized hospital complication associated with poorer outcomes in critically ill children. We aimed to evaluate risk factors for screening positive for delirium in children admitted to a pediatric cardiac intensive care unit (CICU) and...

Caring for patients displaying agitated behaviours in the intensive care unit - A mixed-methods systematic review.

Australian critical care : official journal of the Confederation of Australian Critical Care Nurses

Adams AMN, Chamberlain D, Grønkjær M, Thorup CB, Conroy T.
PMID: 34373173
Aust Crit Care. 2021 Aug 06; doi: 10.1016/j.aucc.2021.05.011. Epub 2021 Aug 06.

BACKGROUND: Patient agitation is common in the intensive care unit (ICU), with consequences for both patients and health professionals if not managed effectively. Research indicates that current practices may not be optimal. A comprehensive review of the evidence exploring...

Use of antipsychotic and sedative medications in older patients in the emergency department.

Journal of the American Geriatrics Society

Kennedy M, Koehl J, Gao J, Ciampa KA, Hayes BD, Camargo CA.
PMID: 34820831
J Am Geriatr Soc. 2021 Nov 25; doi: 10.1111/jgs.17590. Epub 2021 Nov 25.

BACKGROUND: Antipsychotics and sedatives are used to treat agitation in the emergency department (ED) but carry significant risk in older adults. Our objective was to determine factors associated with their administration to older ED patients.METHODS: This was an observational...

Psychotropic medication utilisation in adult cancer patients in China: A cross-sectional study based on national health insurance database.

The Lancet regional health. Western Pacific

Bai L, Xu Z, Huang C, Sui Y, Guan X, Shi L.
PMID: 34327398
Lancet Reg Health West Pac. 2020 Nov 20;5:100060. doi: 10.1016/j.lanwpc.2020.100060. eCollection 2020 Dec.

BACKGROUND: Psychotropic medications are useful to treat psychiatric disorders which are frequently underdiagnosed and undertreated in cancer patients. Evidence on utilisation of psychotropic medications in cancer patients was absent in China. This study aimed to analyse the prevalence and...

Is there a link between the use of benzodiazepines and related drugs and dementia? A systematic review of reviews.

European geriatric medicine

Ferreira P, Ferreira AR, Barreto B, Fernandes L.
PMID: 34403113
Eur Geriatr Med. 2021 Aug 17; doi: 10.1007/s41999-021-00553-w. Epub 2021 Aug 17.

PURPOSE: Benzodiazepines (BZDs) and related drugs (BZRDs) are commonly used to treat diverse psychiatric disorders due to their anxiolytic, hypnotic and sedative properties, despite their known associated side effects, including acute consequences on cognition. Recently, some studies have also...

Effectiveness of virtual reality immersion on procedure-related pain and anxiety in outpatient pain clinic: an exploratory randomized controlled trial.

The Korean journal of pain

Joo Y, Kim EK, Song HG, Jung H, Park H, Moon JY.
PMID: 34193636
Korean J Pain. 2021 Jul 01;34(3):304-314. doi: 10.3344/kjp.2021.34.3.304.

BACKGROUND: The study investigated virtual reality (VR) immersion in alleviating procedure-related pain in patients with chronic pain undergoing fluoroscopy-guided minimally-invasive intervention in a prone position at an outpatient clinic.METHODS: In this prospective randomized controlled study, 38 patients undergoing lumbar...

Fatigue in Aviation: Safety Risks, Preventive Strategies and Pharmacological Interventions.

Frontiers in physiology

Wingelaar-Jagt YQ, Wingelaar TT, Riedel WJ, Ramaekers JG.
PMID: 34552504
Front Physiol. 2021 Sep 06;12:712628. doi: 10.3389/fphys.2021.712628. eCollection 2021.

Fatigue poses an important safety risk to civil and military aviation. In addition to decreasing performance in-flight (chronic) fatigue has negative long-term health effects. Possible causes of fatigue include sleep loss, extended time awake, circadian phase irregularities and work...

Actigraphy in mechanically ventilated pediatric ICU patients: comparison to PSG and evaluation of behavioral circadian rhythmicity.

Chronobiology international

Sanchez REA, Wrede JE, Watson RS, de la Iglesia HO, Dervan LA.
PMID: 34634983
Chronobiol Int. 2021 Oct 11;1-12. doi: 10.1080/07420528.2021.1987451. Epub 2021 Oct 11.

Sleep disruption is common in pediatric intensive care unit (PICU) patients, but measuring sleep in this population is challenging. We aimed to evaluate the utility of actigraphy for estimating circadian rhythmicity in mechanically ventilated PICU patients and its accuracy...

Verification of the performance of the Bispectral Index as a hypnotic depth indicator during dexmedetomidine sedation.

Anesthesia and pain medicine

Ki S, Lee D, Lee W, Cho K, Han Y, Lee J.
PMID: 34784459
Anesth Pain Med (Seoul). 2021 Oct 14; doi: 10.17085/apm.21065. Epub 2021 Oct 14.

BACKGROUND: Differences in the effects of propofol and dexmedetomidine sedation on electroencephalogram patterns have been reported previously. However, the reliability of the Bispectral Index (BIS) value for assessing the sedation caused by dexmedetomidine remains debatable. The purpose of this...

Impact of Propofol Sedation upon Caloric Overfeeding and Protein Inadequacy in Critically Ill Patients Receiving Nutrition Support.

Pharmacy (Basel, Switzerland)

Dickerson RN, Buckley CT.
PMID: 34287346
Pharmacy (Basel). 2021 Jul 01;9(3). doi: 10.3390/pharmacy9030121.

Propofol, a commonly used sedative in the intensive care unit, is formulated in a 10% lipid emulsion that contributes 1.1 kcals per mL. As a result, propofol can significantly contribute to caloric intake and can potentially result in complications...

High Prevalence of Psychotropics Overdose among Suicide Attempters in Korea.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Kim J, Kim M, Kim YR, Choi KH, Lee KU.
PMID: 26598590
Clin Psychopharmacol Neurosci. 2015 Dec 31;13(3):302-7. doi: 10.9758/cpn.2015.13.3.302.

OBJECTIVE: The availability of suicide methods affects the risk of suicide attempts. This study examined the patterns of substances ingested by suicide attempters (SAs) and the characteristics of SAs using psychotropic overdoses.METHODS: Data for 384 of the 462 eligible...

The Sedative Effect of Propranolol on Critically Ill Patients: A Case Series.

Frontiers in medicine

Shiotsuka J, Steel A, Downar J.
PMID: 28523268
Front Med (Lausanne). 2017 May 04;4:44. doi: 10.3389/fmed.2017.00044. eCollection 2017.

INTRODUCTION: Recent studies have examined the effectiveness of alpha-2 adrenergic agonists for controlling delirium and agitation. Propranolol, a non-selective beta-adrenergic antagonist with good penetration of the blood-brain barrier, has not been investigated for this purpose.MATERIALS AND METHODS: We retrospectively...

Showing 25 to 36 of 73 entries