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Showing 25 to 36 of 463 entries
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Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Tomillero A, Moral MA.
PMID: 18985183
Methods Find Exp Clin Pharmacol. 2008 Sep;30(7):543-88.

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug...

Effects of long-term administration of lithium and hydrochlorothiazide in rats.

Metal-based drugs

Loghin F, Olinic A, Popa DS, Socaciu C, Leucuta SE.
PMID: 18475886
Met Based Drugs. 1999;6(2):87-93. doi: 10.1155/MBD.1999.87.

The biochemical and histological changes following 60 days administration of daily doses equivalent to 1/20 LD(50) of lithium lactate and hydrochlorothiazide, as such and in association, were studied in male Wistar rats. No mortality or overt signs of toxicity...

A novel approach to treatment of hypertension in diabetic patients - a multicenter, double-blind, randomized study comparing the efficacy of combination therapy of Eprosartan versus Ramipril with low-dose Hydrochlorothiazide and Moxonidine on blood pressure levels in patients with hypertension and associated diabetes mellitus type 2 - rationale and design [ISRCTN55725285].

Current controlled trials in cardiovascular medicine

Pater C, Bhatnagar D, Berrou JP, Luszick J, Beckmann K.
PMID: 15461784
Curr Control Trials Cardiovasc Med. 2004 Oct 01;5(1):9. doi: 10.1186/1468-6708-5-9.

Hypertension and diabetes mellitus are closely interrelated and coexist in as many as two-thirds of patients with type 2 diabetes. The consequent risk of such an association is an accelerated development of atherosclerotic cardiovascular disease and nephropathy complications.In choosing...

Episodic muscle tremors in a quarter horse: resemblance to hyperkalemic periodic paralysis.

The Canadian veterinary journal = La revue veterinaire canadienne

Steiss JE, Naylor JM.
PMID: 17422693
Can Vet J. 1986 Sep;27(9):332-5.

A three year old Quarter Horse stallion was presented with a one year history of episodes of generalized muscle tremors and stiffness, and spasm of the muscles of facial expression, lasting 10-15 minutes. Between attacks, the horse was either...

Determination of fosinopril in pharmaceutical formulations containing hydrochlorothiazide by multiwavelength UV spectrophotometry.

Talanta

Magri' AL, Balestrieri F, Magri' AD, Marini D.
PMID: 18966407
Talanta. 1995 Nov;42(11):1719-23. doi: 10.1016/0039-9140(95)01642-2.

A sensitive, simple, rapid and precise method for the simultaneous determination of fosinopril (FOS) and hydrochlorothiazide (HCT) in pharmaceutical formulations is presented. These active ingredients are extracted in aqueous solution and measured by multiwavelength UV spectrophotometry using the program...

Valsartan: the past, present and future.

Future cardiology

Køber L, Torp-Pedersen C.
PMID: 19804097
Future Cardiol. 2005 Sep;1(5):591-8. doi: 10.2217/14796678.1.5.591.

Valsartan (Diovan) is a widely use angiotensin receptor blocker that prevents angiotensin II from binding to the subtype 1 receptor. Stimulation of the subtype 1 receptor is believed to mediate many of the deleterious effects accompanied by increased angiotensin...

Derivative and Q-analysis Spectrophotometric Methods for Estimation of Hydrochlorothiazide and Olmesartan Medoxomil in Tablets.

Indian journal of pharmaceutical sciences

Bhusari KP, Khedekar PB, Dhole S, Banode VS.
PMID: 20502567
Indian J Pharm Sci. 2009 Sep;71(5):505-8. doi: 10.4103/0250-474X.58176.

Two methods for simultaneous estimation of hydrochlorothiazide and olmesartan medoxomil in combined tablet dosage form have been developed. The first method is the application of Q-analysis method (absorbance ratio), which involves the formation of Q-absorbance equation at 264 nm...

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Bayes M, Rabasseda X, Prous JR.
PMID: 18040531
Methods Find Exp Clin Pharmacol. 2007 Oct;29(8):547-83.

(-)-Epigallocatechin gallate, [188Re]-P2045, 12B75, 89-12; Abacavir sulfate/lamivudine, Abatacept, Abiraterone acetate, ABT-869, Adalimumab, Ad-rh Endostatin, AI-700, Alemtuzumab, Alvimopan hydrate, Amrubicin hydrochloride, AP-12009, Apomab 7.3, Arformoterol tartrate, Aripiprazole, AS-1404, Azacitidine, AZD-0530; Bevacizumab, BHT-3009, Biapenem, Bortezomib, Bosentan, Bremelanotide; CA9-SCAN, Calcitonin gene-related peptide,...

Cost-effectiveness of medical interventions to prevent cardiovascular disease in a sub-Saharan African country--the case of Tanzania.

Cost effectiveness and resource allocation : C/E

Robberstad B, Hemed Y, Norheim OF.
PMID: 17316431
Cost Eff Resour Alloc. 2007 Feb 22;5:3. doi: 10.1186/1478-7547-5-3.

BACKGROUND: There is a high and rising prevalence of cardiovascular risk in sub-Saharan Africa, a development typical for countries in epidemiological transition. Contrary to recommendations in treatment guidelines, medical interventions to prevent cardiovascular disease are implemented only on a...

Wells syndrome (eosinophilic cellulitis): Proposed diagnostic criteria and a literature review of the drug-induced variant.

Journal of dermatological case reports

Heelan K, Ryan JF, Shear NH, Egan CA.
PMID: 24421864
J Dermatol Case Rep. 2013 Dec 30;7(4):113-20. doi: 10.3315/jdcr.2013.1157. eCollection 2013.

BACKGROUND: Wells syndrome is an uncommon inflammatory dermatosis first described in 1971 by Wells. The clinical eruption is characterized by varying morphology and severity and usually follows a relapsing remitting course. The majority of the reported cases are of...

Stability studies of the effect of crosslinking on hydrochlorothiazide release.

Drug discoveries & therapeutics

Elmeshad AN, Darwish MK.
PMID: 22495541
Drug Discov Ther. 2009 Jun;3(3):136-42.

The aim of this study was to determine the changes in the in vitro drug release from cross-linked hard gelatin capsules containing a water-insoluble drug. An immediate release hydrochlorothiazide (HCTZ) capsule formulations containing drug, lactose, starch 1500 were prepared...

A new spectrophotometric method for the determination of methyldopa.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Gadkariem EA, Ibrahim KE, Kamil NA, Haga ME, El-Obeid HA.
PMID: 23960712
Saudi Pharm J. 2009 Oct;17(4):289-93. doi: 10.1016/j.jsps.2009.10.005. Epub 2009 Nov 10.

A new, simple and low cost spectrophotometric method for the determination of methyldopa in pharmaceutical preparations was developed. The method was based on the coupling of methyldopa with 2,6-dichloroquinone-4-chlorimide (DCQ). The absorbance maximum (λ max) of the resulted colored...

Showing 25 to 36 of 463 entries