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Angiotensin-Converting Enzyme Inhibitors Used Concomitantly with Insulin Secretagogues and the Risk of Serious Hypoglycemia.

Clinical pharmacology and therapeutics

Hee Nam Y, Brensinger CM, Bilker WB, Flory JH, Leonard CE, Hennessy S.
PMID: 34312836
Clin Pharmacol Ther. 2022 Jan;111(1):218-226. doi: 10.1002/cpt.2377. Epub 2021 Aug 23.

Serious hypoglycemia is a major adverse event associated with insulin secretagogues. Previous studies have suggested a potential relationship between angiotensin-converting enzyme inhibitors (ACEIs) used with sulfonylureas and serious hypoglycemia, and widely used drug compendia warn of this potential drug-drug...

Correlates of Insulin Selection as a First-Line Pharmacological Treatment for Gestational Diabetes.

American journal of perinatology

Palatnik A, Harrison RK, Thakkar MY, Walker RJ, Egede LE.
PMID: 34758497
Am J Perinatol. 2021 Nov 10; doi: 10.1055/s-0041-1739266. Epub 2021 Nov 10.

OBJECTIVE:  The aim of this study was to investigate prenatal factors associated with insulin prescription as a first-line pharmacotherapy for gestational diabetes mellitus (GDM; compared with oral antidiabetic medication) after failed medical nutrition therapy.METHODS:  This is a retrospective cohort...

Showing 121 to 122 of 122 entries