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Showing 9625 to 9634 of 9634 entries
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Multifunctional Polymeric Nanogels for Biomedical Applications.

Gels (Basel, Switzerland)

Kaewruethai T, Laomeephol C, Pan Y, Luckanagul JA.
PMID: 34842728
Gels. 2021 Nov 23;7(4). doi: 10.3390/gels7040228.

Currently, research in nanoparticles as a drug delivery system has broadened to include their use as a delivery system for bioactive substances and a diagnostic or theranostic system. Nanogels, nanoparticles containing a high amount of water, have gained attention...

Thermosensitive Polyester Hydrogel for Application of Immunosuppressive Drug Delivery System in Skin Allograft.

Gels (Basel, Switzerland)

Wu IE, Anggelia MR, Lin SY, Chen CY, Chu IM, Lin CH.
PMID: 34842721
Gels. 2021 Nov 23;7(4). doi: 10.3390/gels7040229.

Tacrolimus (FK506) is a common immunosuppressive drug that is capable of suppressing acute rejection reactions, and is used to treat patients after allotransplantation. A stable and suitable serum concentration of tacrolimus is desirable for better therapeutic effects. However, daily...

Alginate hydrogel polymers enable efficient delivery of a vascular-targeted AAV vector into aortic tissue.

Molecular therapy. Methods & clinical development

Remes A, Basha DI, Puehler T, Borowski C, Hille S, Kummer L, Wagner AH, Hecker M, Soethoff J, Lutter G, Frank D, Arif R, Frey N, Zaradzki M, Müller OJ.
PMID: 33768132
Mol Ther Methods Clin Dev. 2021 Feb 24;21:83-93. doi: 10.1016/j.omtm.2021.02.017. eCollection 2021 Jun 11.

Gene therapeutic approaches to aortic diseases require efficient vectors and delivery systems for transduction of endothelial cells (ECs) and smooth muscle cells (SMCs). Here, we developed a novel strategy to efficiently deliver a previously described vascular-specific adeno-associated viral (AAV)...

The Effect of Abiotic Stresses on the Protein Composition of Four Hungarian Wheat Varieties.

Plants (Basel, Switzerland)

Nagy-Réder D, Birinyi Z, Rakszegi M, Békés F, Gell G.
PMID: 35009005
Plants (Basel). 2021 Dec 21;11(1). doi: 10.3390/plants11010001.

Global climate change in recent years has resulted in extreme heat and drought events that significantly influence crop production and endanger food security. Such abiotic stress during the growing season has a negative effect on yield as well as...

Repurposing of nifedipine loaded in situ ophthalmic gel as a novel approach for glaucoma treatment.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

El-Feky YA, Fares AR, Zayed G, El-Telbany RFA, Ahmed KA, El-Telbany DFA.
PMID: 34385102
Biomed Pharmacother. 2021 Oct;142:112008. doi: 10.1016/j.biopha.2021.112008. Epub 2021 Aug 09.

Glaucoma is a chronic eye disease characterized by elevated intraocular pressure (IOP) which causes severe complications to the eyes and may lead to vision loss. The effective treatment of such diseases motivated the search for novel and unique drugs...

Short-Time Changes of Intraocular Pressure and Biomechanics of the Anterior Segment of the Eye during Water Drinking Test in Patients with XEN GelStent.

Journal of clinical medicine

Przeździecka-Dołyk J, Wałek E, Jóźwik A, Helemejko I, Asejczyk-Widlicka M, Misiuk-Hojło M, Samo DD.
PMID: 35011918
J Clin Med. 2021 Dec 29;11(1). doi: 10.3390/jcm11010175.

PURPOSE: Little is known about short-term changes in intraocular pressure (IOP) following minimally invasive glaucoma surgeries, such as post-XEN GelStent implantation. Although the importance of corneal biomechanics in glaucoma diagnostics has been reported, little work has been conducted on...

Cellular heterogeneity and immune microenvironment revealed by single-cell transcriptome in venous malformation and cavernous venous malformation.

Journal of molecular and cellular cardiology

Li Y, Yang J, Huang Y, Ge S, Song X, Jia R, Wang Y.
PMID: 34536440
J Mol Cell Cardiol. 2022 Jan;162:130-143. doi: 10.1016/j.yjmcc.2021.09.004. Epub 2021 Sep 16.

Venous malformation (VM) and cavernous venous malformation (CVM) are two types of vascular malformations. Even if the two diseases are similar in appearance and imaging, the distinct cellular components and signaling pathways between them might help distinguish the two...

Evaluation of an Injectable Hydrogel Based on Hyaluronic Acid-Chitosan/β-Glycerophosphate-Loaded Mesenchymal Stem Cells in Enhancing the Therapeutic Efficacy of Myocardial Infarction.

Macromolecular bioscience

Peng L, Li M, Zhao K, Ma C, Tang H, Li Y.
PMID: 34676668
Macromol Biosci. 2021 Oct 21;e2100286. doi: 10.1002/mabi.202100286. Epub 2021 Oct 21.

Myocardial infarction (MI), which is due to cardiac dysfunction, results in morbidity and mortality. Moreover, the cellular activity of transplanted mesenchymal stem cells (MSCs) generally limits their therapeutic efficacy in the treatment of MI. Here, inject able hyaluronic acid-chitosan/β-glycerophosphate...

Acquisition of Transmission Electron Microscope for Interdisciplinary Research.

[No authors listed]
UIID-NSF: 1078

This project from an EPSCoR state, involving interdisciplinary research in nanotechnology, nanodevices, materials science, chemistry, biomedical engineering, and related fields, aims at acquiring a high resolution Transmission Electron Microscope (TEM). The project investigates the properties of nanostructural materials and...

An entrepreneurial training model to enhance undergraduate training in biomedical research.

Hohmann C, Hughes-Darden C, Kamangar F, Silver G, Turner-Musa J, Haines RT, Jackson A, Aguila N, Sheikhattari P.
UIID-AD: 4828
2017; doi: 10.1186/s12919-017-0091-8.

Background: Undergraduate students who are interested in biomedical research typically work on a faculty member's research project, conduct one distinct task (e.g., running gels), and, step by step, enhance their skills. This "apprenticeship" model has been helpful in training...

Showing 9625 to 9634 of 9634 entries