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Showing 3013 to 3024 of 3046 entries
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SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase.

Cell reports

Choi WY, Kim S, Aurass P, Huo W, Creasey EA, Edwards M, Lowe M, Isberg RR.
PMID: 34731604
Cell Rep. 2021 Nov 02;37(5):109894. doi: 10.1016/j.celrep.2021.109894.

Legionella pneumophila grows intracellularly within a replication vacuole via action of Icm/Dot-secreted proteins. One such protein, SdhA, maintains the integrity of the vacuolar membrane, thereby preventing cytoplasmic degradation of bacteria. We show here that SdhA binds and blocks the...

STATegra: Multi-Omics Data Integration - A Conceptual Scheme With a Bioinformatics Pipeline.

Frontiers in genetics

Planell N, Lagani V, Sebastian-Leon P, van der Kloet F, Ewing E, Karathanasis N, Urdangarin A, Arozarena I, Jagodic M, Tsamardinos I, Tarazona S, Conesa A, Tegner J, Gomez-Cabrero D.
PMID: 33747045
Front Genet. 2021 Mar 04;12:620453. doi: 10.3389/fgene.2021.620453. eCollection 2021.

Technologies for profiling samples using different omics platforms have been at the forefront since the human genome project. Large-scale multi-omics data hold the promise of deciphering different regulatory layers. Yet, while there is a myriad of bioinformatics tools, each...

Symptomatic Internal Carotid Artery Vasa Vasorum Treated With Surgical Occlusion.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

Hawkes C, Durant C, van Adel B.
PMID: 33766184
Can J Neurol Sci. 2021 Mar 26;1-2. doi: 10.1017/cjn.2021.49. Epub 2021 Mar 26.

No abstract available.

Monomers and Macromolecular Materials from Renewable Resources: State of the Art and Perspectives.

Molecules (Basel, Switzerland)

Gandini A, M Lacerda T.
PMID: 35011391
Molecules. 2021 Dec 28;27(1). doi: 10.3390/molecules27010159.

A progressively increasing concern about the environmental impacts of the whole polymer industry has boosted the design of less aggressive technologies that allow for the maximum use of carbon atoms, and reduced dependence on the fossil platform. Progresses related...

Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits.

Genome research

Orchard P, Manickam N, Ventresca C, Vadlamudi S, Varshney A, Rai V, Kaplan J, Lalancette C, Mohlke KL, Gallagher K, Burant CF, Parker SCJ.
PMID: 34815310
Genome Res. 2021 Nov 23; doi: 10.1101/gr.268482.120. Epub 2021 Nov 23.

Skeletal muscle accounts for the largest proportion of human body mass, on average, and is a key tissue in complex diseases and mobility. It is composed of several different cell and muscle fiber types. Here, we optimize single-nucleus ATAC-seq...

Unexpected Outcomes of Measuring Decision Regret: Using a Breast Cancer Decision-Making Case Example.

The patient

Oman K, Durand MA, Elwyn G, Yen RW, Marx C, Politi MC.
PMID: 34337674
Patient. 2021 Aug 02; doi: 10.1007/s40271-021-00543-x. Epub 2021 Aug 02.

Shared decision making can help patients feel supported and empowered when deciding between healthcare options. Decision regret can be a meaningful measure of the quality of that encounter. However, in a patient-engaged research study examining shared decision making for...

Discussion: Cone-Beam Computed Tomography: A User-Friendly, Practical Roadmap to the Planning and Execution of Every Rhinoplasty-A 5-Year Review.

Plastic and reconstructive surgery

Durand PD.
PMID: 33890888
Plast Reconstr Surg. 2021 May 01;147(5):763e-764e. doi: 10.1097/PRS.0000000000007912.

No abstract available.

Reduced organizational skills in adults with ADHD are due to deficits in persistence, not in strategies.

PeerJ

Durand G, Arbone IS, Wharton M.
PMID: 33194353
PeerJ. 2020 Sep 08;8:e9844. doi: 10.7717/peerj.9844. eCollection 2020.

BACKGROUND: Attention Deficit Hyperactivity Disorder (ADHD) is commonly associated with poor organizational skills, as per the definition of ADHD. However, the contribution of each of the following factors (and their interactions) to the aforementioned poor organization, while comparing individuals...

Low concentrations of glyphosate alone affect the pubertal male rat meiotic step: An in vitro study.

Toxicology in vitro : an international journal published in association with BIBRA

Antonine B, Guillaume M, Philippe D, Marie-Hélène P.
PMID: 34864054
Toxicol In Vitro. 2021 Dec 03;79:105291. doi: 10.1016/j.tiv.2021.105291. Epub 2021 Dec 03.

Glyphosate is the most used herbicide in the world. Controversial studies exist on its effect on the male reproductive system. We used the validated BioAlter® model to test the effects of low concentrations of Glyphosate. Pubertal rat seminiferous tubules...

The identification of needs and development of best practice guidance for the psychological support of frontline healthcare workers during and after COVID-19: A protocol for the FLoWS project.

HRB open research

Flynn J, O'Connor L, Hanlon M, Bellani G, Contreras M, Doherty A, Durand H, Fallon E, Gormley C, Laffey J, Molloy G, Sarma K, Strepparava MG, Russo S, Walsh J, McGuire BE.
PMID: 33870088
HRB Open Res. 2021 Jan 29;3:54. doi: 10.12688/hrbopenres.13117.2. eCollection 2020.

Recent estimates suggest that up to 34% of frontline workers in healthcare (FLWs) at the forefront of the COVID-19 pandemic response are reporting elevated symptoms of psychological distress due to resource constraints, ineffective treatments, and concerns about self-contamination. However,...

Multivariable passive ankle impedance in stroke patients: A preliminary study.

Journal of biomechanics

Moura Coelho R, Durand S, Martins J, Igo Krebs H.
PMID: 34749162
J Biomech. 2021 Oct 30;130:110829. doi: 10.1016/j.jbiomech.2021.110829. Epub 2021 Oct 30.

Multivariable ankle mechanical impedance was estimated in four stroke survivors, in coupled dorsi- plantarflexion and inversion-eversion. We applied external torque perturbation with an ankle robot and used multi-input, multi-output stochastic system identification methods to estimate impedance, in both paretic...

Changes in axial hydraulic conductivity along elongating leaf blades in relation to xylem maturation in tall fescue.

The New phytologist

Martre P, Durand JL, Cochard H.
PMID: 33862978
New Phytol. 2000 May;146(2):235-247. doi: 10.1046/j.1469-8137.2000.00641.x.

Xylem maturation in elongating leaf blades of tall fescue (Festuca arundinacea) was studied using staining and microcasting. Three distinctive regions were identified in the blade: (1) a basal region, in which elongation was occurring and protoxylem (PX) vessels were...

Showing 3013 to 3024 of 3046 entries