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Showing 1429 to 1439 of 1439 entries
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Fabrication of pure-drug microneedles for delivery of montelukast sodium.

Drug delivery and translational research

Azizoglu E, Ozer O, Prausnitz MR.
PMID: 34480297
Drug Deliv Transl Res. 2021 Sep 03; doi: 10.1007/s13346-021-01047-9. Epub 2021 Sep 03.

Dissolving microneedle (MN) patches are usually formulated with a blend of drug and excipients added for mechanical strength and drug stabilization. In this study, we developed MNs made of pure drug to maximize drug loading capacity. MN patches were...

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Azizoglu E, Ozer O, Prausnitz MR. Fabrication of pure-drug microneedles for delivery of montelukast sodium. Drug Deliv Transl Res. 2021;doi: 10.1007/s13346-021-01047-9.
Azizoglu, E., Ozer, O., & Prausnitz, M. R. (2021). Fabrication of pure-drug microneedles for delivery of montelukast sodium. Drug delivery and translational research, . https://doi.org/10.1007/s13346-021-01047-9
Azizoglu, Erkan, et al. "Fabrication of pure-drug microneedles for delivery of montelukast sodium." Drug delivery and translational research vol. (2021). doi: https://doi.org/10.1007/s13346-021-01047-9
Azizoglu E, Ozer O, Prausnitz MR. Fabrication of pure-drug microneedles for delivery of montelukast sodium. Drug Deliv Transl Res. 2021 Sep 03; doi: 10.1007/s13346-021-01047-9. Epub 2021 Sep 03. PMID: 34480297.
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Comparison of Flow and Compression Properties of Four Lactose-Based Co-Processed Excipients: Cellactose.

Pharmaceutics

Dominik M, Vraníková B, Svačinová P, Elbl J, Pavloková S, Prudilová BB, Šklubalová Z, Franc A.
PMID: 34575562
Pharmaceutics. 2021 Sep 16;13(9). doi: 10.3390/pharmaceutics13091486.

The utilization of co-processed excipients (CPEs) represents a novel approach to the preparation of orally disintegrating tablets by direct compression. Flow, consolidation, and compression properties of four lactose-based CPEs-Cellactose

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Dominik M, Vraníková B, Svačinová P, et al. Comparison of Flow and Compression Properties of Four Lactose-Based Co-Processed Excipients: Cellactose. Pharmaceutics. 2021;13(9)doi: 10.3390/pharmaceutics13091486.
Dominik, M., Vraníková, B., Svačinová, P., Elbl, J., Pavloková, S., Prudilová, B. B., Šklubalová, Z., & Franc, A. (2021). Comparison of Flow and Compression Properties of Four Lactose-Based Co-Processed Excipients: Cellactose. Pharmaceutics, 13(9), . https://doi.org/10.3390/pharmaceutics13091486
Dominik, Martin, et al. "Comparison of Flow and Compression Properties of Four Lactose-Based Co-Processed Excipients: Cellactose." Pharmaceutics vol. 13,9 (2021). doi: https://doi.org/10.3390/pharmaceutics13091486
Dominik M, Vraníková B, Svačinová P, Elbl J, Pavloková S, Prudilová BB, Šklubalová Z, Franc A. Comparison of Flow and Compression Properties of Four Lactose-Based Co-Processed Excipients: Cellactose. Pharmaceutics. 2021 Sep 16;13(9). doi: 10.3390/pharmaceutics13091486. PMID: 34575562; PMCID: PMC8467879.
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Evaluation and Characterization of Tamarind Gum Polysaccharide: The Biopolymer.

Polymers

Malviya R, Sundram S, Fuloria S, Subramaniyan V, Sathasivam KV, Azad AK, Sekar M, Kumar DH, Chakravarthi S, Porwal O, Meenakshi DU, Fuloria NK.
PMID: 34577925
Polymers (Basel). 2021 Sep 07;13(18). doi: 10.3390/polym13183023.

Polymers from natural sources are widely used as excipients in the formulation of pharmaceutical dosage forms. The objective of this study was to extract and further characterize the tamarind gum polysaccharide (TGP) obtained from

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Malviya R, Sundram S, Fuloria S, et al. Evaluation and Characterization of Tamarind Gum Polysaccharide: The Biopolymer. Polymers (Basel). 2021;13(18)doi: 10.3390/polym13183023.
Malviya, R., Sundram, S., Fuloria, S., Subramaniyan, V., Sathasivam, K. V., Azad, A. K., Sekar, M., Kumar, D. H., Chakravarthi, S., Porwal, O., Meenakshi, D. U., & Fuloria, N. K. (2021). Evaluation and Characterization of Tamarind Gum Polysaccharide: The Biopolymer. Polymers, 13(18), . https://doi.org/10.3390/polym13183023
Malviya, Rishabha, et al. "Evaluation and Characterization of Tamarind Gum Polysaccharide: The Biopolymer." Polymers vol. 13,18 (2021). doi: https://doi.org/10.3390/polym13183023
Malviya R, Sundram S, Fuloria S, Subramaniyan V, Sathasivam KV, Azad AK, Sekar M, Kumar DH, Chakravarthi S, Porwal O, Meenakshi DU, Fuloria NK. Evaluation and Characterization of Tamarind Gum Polysaccharide: The Biopolymer. Polymers (Basel). 2021 Sep 07;13(18). doi: 10.3390/polym13183023. PMID: 34577925; PMCID: PMC8467713.
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Preparation and evaluation of vancomycin spray-dried powders for pulmonary delivery.

Pharmaceutical development and technology

Bahrainian S, Rouini M, Gilani K.
PMID: 33896355
Pharm Dev Technol. 2021 Jul;26(6):647-660. doi: 10.1080/10837450.2021.1915331. Epub 2021 May 05.

The aim of the current study was to achieve a dry powder formulation of vancomycin by spray drying whilst evaluating the effect of pH and excipient type and percentage used in formulation on particle characteristics and aerosolization performance. A...

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Bahrainian S, Rouini M, Gilani K. Preparation and evaluation of vancomycin spray-dried powders for pulmonary delivery. Pharm Dev Technol. 2021;26(6):647-660doi: 10.1080/10837450.2021.1915331.
Bahrainian, S., Rouini, M., & Gilani, K. (2021). Preparation and evaluation of vancomycin spray-dried powders for pulmonary delivery. Pharmaceutical development and technology, 26(6), 647-660. https://doi.org/10.1080/10837450.2021.1915331
Bahrainian, Sara, et al. "Preparation and evaluation of vancomycin spray-dried powders for pulmonary delivery." Pharmaceutical development and technology vol. 26,6 (2021): 647-660. doi: https://doi.org/10.1080/10837450.2021.1915331
Bahrainian S, Rouini M, Gilani K. Preparation and evaluation of vancomycin spray-dried powders for pulmonary delivery. Pharm Dev Technol. 2021 Jul;26(6):647-660. doi: 10.1080/10837450.2021.1915331. Epub 2021 May 05. PMID: 33896355.
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Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies.

Pharmaceutics

Majid H, Puzik A, Maier T, Merk R, Bartel A, Mueller HC, Burckhardt BB.
PMID: 34575485
Pharmaceutics. 2021 Sep 06;13(9). doi: 10.3390/pharmaceutics13091409.

Suitable ex vivo models are required as predictive tools of oromucosal permeability between in vitro characterizations and in vivo studies in order to support the development of novel intraoral formulations. To counter a lack of clinical relevance and observed...

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Majid H, Puzik A, Maier T, et al. Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies. Pharmaceutics. 2021;13(9)doi: 10.3390/pharmaceutics13091409.
Majid, H., Puzik, A., Maier, T., Merk, R., Bartel, A., Mueller, H. C., & Burckhardt, B. B. (2021). Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies. Pharmaceutics, 13(9), . https://doi.org/10.3390/pharmaceutics13091409
Majid, Haidara, et al. "Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies." Pharmaceutics vol. 13,9 (2021). doi: https://doi.org/10.3390/pharmaceutics13091409
Majid H, Puzik A, Maier T, Merk R, Bartel A, Mueller HC, Burckhardt BB. Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies. Pharmaceutics. 2021 Sep 06;13(9). doi: 10.3390/pharmaceutics13091409. PMID: 34575485; PMCID: PMC8472530.
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Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL-35.

Pharmaceutics

Wen C, Hu H, Zhang W, Liu X, Jiang X, Wang L.
PMID: 34575568
Pharmaceutics. 2021 Sep 17;13(9). doi: 10.3390/pharmaceutics13091492.

Pharmaceutical excipients (PEs) are substances included in drug formulations. Recent studies have revealed that some PEs can affect the activity of metabolic enzymes and drug transporters; however, the effects of PEs on CYP2C8 and its interaction potential with drugs...

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Wen C, Hu H, Zhang W, et al. Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL-35. Pharmaceutics. 2021;13(9)doi: 10.3390/pharmaceutics13091492.
Wen, C., Hu, H., Zhang, W., Liu, X., Jiang, X., & Wang, L. (2021). Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL-35. Pharmaceutics, 13(9), . https://doi.org/10.3390/pharmaceutics13091492
Wen, Chengming, et al. "Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL-35." Pharmaceutics vol. 13,9 (2021). doi: https://doi.org/10.3390/pharmaceutics13091492
Wen C, Hu H, Zhang W, Liu X, Jiang X, Wang L. Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL-35. Pharmaceutics. 2021 Sep 17;13(9). doi: 10.3390/pharmaceutics13091492. PMID: 34575568; PMCID: PMC8467590.
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Temperature-dependence of riboflavin phosphorescence in cryosolvents.

Food chemistry

Wang Y, Corradini MG, Ludescher RD.
PMID: 34968903
Food Chem. 2021 Dec 23;376:131928. doi: 10.1016/j.foodchem.2021.131928. Epub 2021 Dec 23.

The molecular mobility of amorphous excipients is important for the stability of biomaterials during preservation, facilitating matrix formulation and product design. Phosphorescence spectroscopy is a sensitive optical method to study molecular mobility. However, there is a need to expand...

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Wang Y, Corradini MG, Ludescher RD. Temperature-dependence of riboflavin phosphorescence in cryosolvents. Food Chem. 2021;376:131928doi: 10.1016/j.foodchem.2021.131928.
Wang, Y., Corradini, M. G., & Ludescher, R. D. (2021). Temperature-dependence of riboflavin phosphorescence in cryosolvents. Food chemistry, 376131928. https://doi.org/10.1016/j.foodchem.2021.131928
Wang, Yan, et al. "Temperature-dependence of riboflavin phosphorescence in cryosolvents." Food chemistry vol. 376 (2021): 131928. doi: https://doi.org/10.1016/j.foodchem.2021.131928
Wang Y, Corradini MG, Ludescher RD. Temperature-dependence of riboflavin phosphorescence in cryosolvents. Food Chem. 2021 Dec 23;376:131928. doi: 10.1016/j.foodchem.2021.131928. Epub 2021 Dec 23. PMID: 34968903.
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Thermal analysis of mammalian stratum corneum using differential scanning calorimetry for advancing skin research and drug delivery.

International journal of pharmaceutics

Goh CF, Hadgraft J, Lane ME.
PMID: 34998922
Int J Pharm. 2022 Jan 05;614:121447. doi: 10.1016/j.ijpharm.2021.121447. Epub 2022 Jan 05.

For effective topical and transdermal drug delivery, it is necessary for most actives to penetrate and permeate through the stratum corneum (SC). Extensive investigation of the thermal behaviour of mammalian SC has been performed to understand the barrier function...

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Goh CF, Hadgraft J, Lane ME. Thermal analysis of mammalian stratum corneum using differential scanning calorimetry for advancing skin research and drug delivery. Int J Pharm. 2022;614:121447doi: 10.1016/j.ijpharm.2021.121447.
Goh, C. F., Hadgraft, J., & Lane, M. E. (2022). Thermal analysis of mammalian stratum corneum using differential scanning calorimetry for advancing skin research and drug delivery. International journal of pharmaceutics, 614121447. https://doi.org/10.1016/j.ijpharm.2021.121447
Goh, Choon Fu, et al. "Thermal analysis of mammalian stratum corneum using differential scanning calorimetry for advancing skin research and drug delivery." International journal of pharmaceutics vol. 614 (2022): 121447. doi: https://doi.org/10.1016/j.ijpharm.2021.121447
Goh CF, Hadgraft J, Lane ME. Thermal analysis of mammalian stratum corneum using differential scanning calorimetry for advancing skin research and drug delivery. Int J Pharm. 2022 Jan 05;614:121447. doi: 10.1016/j.ijpharm.2021.121447. Epub 2022 Jan 05. PMID: 34998922.
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Levothyroxine Sodium Pentahydrate Tablets - Formulation Considerations.

Journal of pharmaceutical sciences

Kaur N, Suryanarayanan R.
PMID: 34384799
J Pharm Sci. 2021 Dec;110(12):3743-3756. doi: 10.1016/j.xphs.2021.08.006. Epub 2021 Aug 10.

Even though levothyroxine sodium pentahydrate tablets have been in the market since 1955, there continue to be recalls due to sub potency. We have comprehensively reviewed the factors affecting its stability in solid oral dosage forms. A compilation of...

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Kaur N, Suryanarayanan R. Levothyroxine Sodium Pentahydrate Tablets - Formulation Considerations. J Pharm Sci. 2021;110(12):3743-3756doi: 10.1016/j.xphs.2021.08.006.
Kaur, N., & Suryanarayanan, R. (2021). Levothyroxine Sodium Pentahydrate Tablets - Formulation Considerations. Journal of pharmaceutical sciences, 110(12), 3743-3756. https://doi.org/10.1016/j.xphs.2021.08.006
Kaur, Navpreet, and Suryanarayanan, Raj. "Levothyroxine Sodium Pentahydrate Tablets - Formulation Considerations." Journal of pharmaceutical sciences vol. 110,12 (2021): 3743-3756. doi: https://doi.org/10.1016/j.xphs.2021.08.006
Kaur N, Suryanarayanan R. Levothyroxine Sodium Pentahydrate Tablets - Formulation Considerations. J Pharm Sci. 2021 Dec;110(12):3743-3756. doi: 10.1016/j.xphs.2021.08.006. Epub 2021 Aug 10. PMID: 34384799.
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Binder jetting 3D printing of challenging medicines: From low dose tablets to hydrophobic molecules.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Kozakiewicz-Latała M, Nartowski KP, Dominik A, Malec K, Gołkowska AM, Złocińska A, Rusińska M, Szymczyk-Ziółkowska P, Ziółkowski G, Górniak A, Karolewicz B.
PMID: 34785345
Eur J Pharm Biopharm. 2022 Jan;170:144-159. doi: 10.1016/j.ejpb.2021.11.001. Epub 2021 Nov 13.

Increasing access to additive manufacturing technologies utilising easily available desktop devices opened novel ways for formulation of personalized medicines. It is, however, challenging to propose a flexible and robust formulation platform which can be used for fabrication of tailored...

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Kozakiewicz-Latała M, Nartowski KP, Dominik A, et al. Binder jetting 3D printing of challenging medicines: From low dose tablets to hydrophobic molecules. Eur J Pharm Biopharm. 2021;170:144-159doi: 10.1016/j.ejpb.2021.11.001.
Kozakiewicz-Latała, M., Nartowski, K. P., Dominik, A., Malec, K., Gołkowska, A. M., Złocińska, A., Rusińska, M., Szymczyk-Ziółkowska, P., Ziółkowski, G., Górniak, A., & Karolewicz, B. (2022). Binder jetting 3D printing of challenging medicines: From low dose tablets to hydrophobic molecules. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 170144-159. https://doi.org/10.1016/j.ejpb.2021.11.001
Kozakiewicz-Latała, Marta, et al. "Binder jetting 3D printing of challenging medicines: From low dose tablets to hydrophobic molecules." European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V vol. 170 (2022): 144-159. doi: https://doi.org/10.1016/j.ejpb.2021.11.001
Kozakiewicz-Latała M, Nartowski KP, Dominik A, Malec K, Gołkowska AM, Złocińska A, Rusińska M, Szymczyk-Ziółkowska P, Ziółkowski G, Górniak A, Karolewicz B. Binder jetting 3D printing of challenging medicines: From low dose tablets to hydrophobic molecules. Eur J Pharm Biopharm. 2022 Jan;170:144-159. doi: 10.1016/j.ejpb.2021.11.001. Epub 2021 Nov 13. PMID: 34785345.
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The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation.

International journal of pharmaceutics: X

Bluemel O, Anuschek M, Buecheler JW, Hoelzl G, Bechtold-Peters K, Friess W.
PMID: 35024603
Int J Pharm X. 2021 Dec 25;4:100108. doi: 10.1016/j.ijpx.2021.100108. eCollection 2022 Dec.

Cryoconcentration upon large-scale freezing of monoclonal antibody (mAb) solutions leads to regions of different ratios of low molecular weight excipients, like buffer species or sugars, to protein. This study focused on the impact of the buffer species to mAb...

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Bluemel O, Anuschek M, Buecheler JW, et al. The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation. Int J Pharm X. 2021;4:100108doi: 10.1016/j.ijpx.2021.100108.
Bluemel, O., Anuschek, M., Buecheler, J. W., Hoelzl, G., Bechtold-Peters, K., & Friess, W. (2022). The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation. International journal of pharmaceutics: X, 4100108. https://doi.org/10.1016/j.ijpx.2021.100108
Bluemel, Oliver, et al. "The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation." International journal of pharmaceutics: X vol. 4 (2022): 100108. doi: https://doi.org/10.1016/j.ijpx.2021.100108
Bluemel O, Anuschek M, Buecheler JW, Hoelzl G, Bechtold-Peters K, Friess W. The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation. Int J Pharm X. 2021 Dec 25;4:100108. doi: 10.1016/j.ijpx.2021.100108. eCollection 2022 Dec. PMID: 35024603; PMCID: PMC8724966.
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Showing 1429 to 1439 of 1439 entries