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Showing 25 to 36 of 1811 entries
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Synthesis of CaCO3 Nanobelts for Drug Delivery in Cancer Therapy.

Nanoscale research letters

Sun D, Peng H, Wang S, Zhu D.
PMID: 26055480
Nanoscale Res Lett. 2015 Dec;10(1):948. doi: 10.1186/s11671-015-0948-6. Epub 2015 May 27.

Nanobelt carriers have demonstrated some advantages such as good biocompatibility, biodegradability, and strain-accommodating properties. We prepared an optimized nanobelt carrier formulation for drug (etoposide) as an oral delivery system and estimated the potential of calcium carbonate (CaCO3) nanobelts. The...

The Relation between Histopathologic Findings on Surgical Specimen and Outcomes in Patients with N2 Positive Stage IIIA Non-Small Cell Lung Cancer Receiving Preoperative Concurrent Radiochemotherapy and Surgery.

Cancer research and treatment

Kim BK, Kim KJ, Ahn YC, Lim DH, Park W, Han J, Park K, Kim KM, Kim J, Shim YM.
PMID: 26680981
Cancer Res Treat. 2003 Dec;35(6):497-501. doi: 10.4143/crt.2003.35.6.497.

PURPOSE: To evaluate the prognostic implication of histopathologic findings on the surgical specimens of N2 positive stage IIIA non-small cell lung cancer (NSCLC) patients who were treated with preoperative concurrent radiochemotherapy (CRCT) and surgery.MATERIALS AND METHODS: From May 1997...

A Literature Review and Case Report of Metastatic Pure Choriocarcinoma.

Case reports in oncological medicine

Lin D, Tan AJ, Singh-Rai R.
PMID: 26649213
Case Rep Oncol Med. 2015;2015:345018. doi: 10.1155/2015/345018. Epub 2015 Nov 16.

In 2012, testicular cancer was estimated to account for 940 disability adjusted life years in Australia; of these, 450 were years lost due to premature death and 500 were years of healthy life lost due to disease, disability, or...

26,26,26,27,27,27-Hexadeuterated-1,25-Dihydroxyvitamin D3 (1,25D-d6) As Adjuvant of Chemotherapy in Breast Cancer Cell Lines.

Cancers

Seoane S, Bermudez MA, Sendon-Lago J, Martinez-Ordoñez A, Abdul-Hadi S, Maestro M, Mouriño A, Perez-Fernandez R.
PMID: 24378752
Cancers (Basel). 2013 Dec 27;6(1):67-78. doi: 10.3390/cancers6010067.

It has been demonstrated that 1,25-dihydroxyvitamin D3 (1,25D) and some of its analogues have antitumor activity. 1,25D labeled with deuterium (26,26,26,27,27,27-hexadeuterated 1a,25-dihydroxyvitamin D3, or 1,25D-d6) is commonly used as internal standard for 1,25D liquid chromatography-mass spectrometry (LC-MS) quantification. In...

Caspase-dependent drug-induced apoptosis is regulated by cell surface sialylation in human B-cell lymphoma.

Oncology letters

Suzuki O, Abe M, Hashimoto Y.
PMID: 26622554
Oncol Lett. 2015 Aug;10(2):687-690. doi: 10.3892/ol.2015.3320. Epub 2015 Jun 04.

The important role of sialic acid in various biological phenomena is well-established. In order to further clarify the role of sialic acid in cell death induced by various stimuli, the present study compared the cell survival of the HBL-2...

Molecular Profiling of Refractory Adrenocortical Cancers and Predictive Biomarkers to Therapy.

Biomarkers in cancer

Millis SZ, Ejadi S, Demeure MJ.
PMID: 26715866
Biomark Cancer. 2015 Dec 17;7:69-76. doi: 10.4137/BIC.S34292. eCollection 2015.

PURPOSE: Current first-line chemotherapy for patients with metastatic adrenocortical cancer (ACC) includes doxorubicin, etoposide, cisplatin, and mitotane with a reported response rate of only 23.2%. New therapeutic leads for patients with refractory tumors are needed; there is no standard...

Outcomes of adult medulloblastoma treated with a multimodality approach: A tertiary cancer center experience.

South Asian journal of cancer

Mallick S, Gandhi AK, Benson R, Sharma DN, Haresh KP, Gupta S, Julka PK, Rath GK.
PMID: 26981508
South Asian J Cancer. 2015 Oct-Dec;4(4):174-8. doi: 10.4103/2278-330X.175954.

OBJECTIVES: Adult medulloblastoma (AMB) is a rare central nervous system tumor. We aimed to analyze the treatment outcomes of AMB treated at our institute with surgery followed by craniospinal irradiation (CSI) and adjuvant chemotherapy.METHODS: We retrospectively evaluated the treatment...

A case of Takotsubo cardiomyopathy after chemotherapy.

Oxford medical case reports

Malley T, Watson E.
PMID: 27066260
Oxf Med Case Reports. 2016 Apr 07;2016(4):55-8. doi: 10.1093/omcr/omw014. eCollection 2016 Apr.

Here we present the case of a patient with diffuse large B-cell lymphoma who was admitted to hospital for an elective autologous peripheral blood stem cell transplant after cytotoxic treatment with lomustine, cytarabine, cyclophosphomide and etoposide (LACE). On the...

Immune Reactivity and Pseudoprogression or Tumor Flare in a Serially Biopsied Neuroendocrine Patient Treated with the Epigenetic Agent RRx-001.

Case reports in oncology

Carter CA, Schmitz B, Peterson PG, Quinn M, Degesys A, Jenkins J, Oronsky B, Scicinski J, Caroen S, Reid TR, Cabrales P, Brzezniak C.
PMID: 27065848
Case Rep Oncol. 2016 Mar 10;9(1):164-70. doi: 10.1159/000444633. eCollection 2016.

Neuroendocrine tumors (NETs) are grouped together as a single class on the basis of histologic appearance, immunoreactivity for the neuroendocrine markers chromogranin A and synaptophysin, and potential secretion of hormones, neurotransmitters, neuromodulators and neuropeptides. Nevertheless, despite these common characteristics,...

Biochemical remission by chemoradiotherapy in male mediastinal choriocarcinoma with diffuse lung metastasis: A case report.

Oncology letters

Zhang J, Wang ZJ, Yang B, Wei YY, Yang L, Hu Y, Hu YP.
PMID: 27073527
Oncol Lett. 2016 Apr;11(4):2615-2618. doi: 10.3892/ol.2016.4248. Epub 2016 Feb 18.

Primary mediastinal choriocarcinoma is a rare malignancy that is characterized by multiple metastases at the time of diagnosis, poor response to therapy and short survival times. There is no standard treatment for this disease. The present study described the...

Claudin 1 Promotes Migration and Increases Sensitivity to Tamoxifen and Anticancer Drugs in Luminal-like Human Breast Cancer Cells MCF7.

Cancer investigation

Zhou B, Blanchard A, Wang N, Ma X, Han J, Schroedter I, Leygue E, Myal Y.
PMID: 26279089
Cancer Invest. 2015 Aug 17; Epub 2015 Aug 17.

Downregulation of claudin 1, a critical tight junction protein, has been correlated with increased invasiveness in breast cancer. However, recent studies suggest that claudin 1 contributes to the progression of some molecular subtypes of breast cancer. In this study,...

Chemotherapy-induced endometrial pathology: mimicry of malignancy and viral endometritis.

American journal of translational research

Kim EK, Yoon G, Kim HS.
PMID: 27347355
Am J Transl Res. 2016 May 15;8(5):2459-67. eCollection 2016.

Chemotherapy is a common type of preoperative neoadjuvant treatment and postoperative adjuvant or palliative therapy for many different types of malignancies. Certain chemotherapeutic agents can induce bizarre epithelial atypia that mimics malignancy. Unfamiliarity with these changes could potentially cause...

Showing 25 to 36 of 1811 entries