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Showing 13 to 14 of 14 entries
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Chiral ammonium betaine-catalyzed highly stereoselective aza-henry reaction of α-aryl nitromethanes with aromatic N-Boc imines.

Chemistry, an Asian journal

Uraguchi D, Oyaizu K, Noguchi H, Ooi T.
PMID: 25338974
Chem Asian J. 2015 Feb;10(2):334-7. doi: 10.1002/asia.201402943. Epub 2014 Oct 22.

A highly stereoselective aza-Henry reaction of α-aryl nitromethanes with aromatic N-Boc imines was established by using C1 -symmetric chiral ammonium betaine as a bifunctional organic base catalyst. Various substituted aryl groups for both imines and nitromethanes were tolerated in...

Ethylenediamine derivatives efficiently react with oxidized RNA 3' ends providing access to mono and dually labelled RNA probes for enzymatic assays and in vivo translation.

Nucleic acids research

Mamot A, Sikorski PJ, Siekierska A, de Witte P, Kowalska J, Jemielity J.
PMID: 34591964
Nucleic Acids Res. 2021 Sep 30; doi: 10.1093/nar/gkab867. Epub 2021 Sep 30.

Development of RNA-based technologies relies on the ability to detect, manipulate, and modify RNA. Efficient, selective and scalable covalent modification of long RNA molecules remains a challenge. We report a chemical method for modification of RNA 3'-end based on...

Showing 13 to 14 of 14 entries